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Items: 20

1.

A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation.

Hoffman KS, Vargas-Rodriguez O, Bak DW, Mukai T, Woodward LK, Weerapana E, Söll D, Reynolds NM.

J Biol Chem. 2019 Aug 23;294(34):12855-12865. doi: 10.1074/jbc.RA119.008219. Epub 2019 Jul 11.

PMID:
31296657
2.

Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases.

Crnković A, Vargas-Rodriguez O, Söll D.

Int J Mol Sci. 2019 May 9;20(9). pii: E2294. doi: 10.3390/ijms20092294. Review.

3.

Engineered Aminoacyl-tRNA Synthetases with Improved Selectivity toward Noncanonical Amino Acids.

Kwok HS, Vargas-Rodriguez O, Melnikov SV, Söll D.

ACS Chem Biol. 2019 Apr 19;14(4):603-612. doi: 10.1021/acschembio.9b00088. Epub 2019 Apr 9.

4.

Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.

Melnikov SV, Khabibullina NF, Mairhofer E, Vargas-Rodriguez O, Reynolds NM, Micura R, Söll D, Polikanov YS.

Nucleic Acids Res. 2019 Feb 28;47(4):2089-2100. doi: 10.1093/nar/gky1211.

5.

Upgrading aminoacyl-tRNA synthetases for genetic code expansion.

Vargas-Rodriguez O, Sevostyanova A, Söll D, Crnković A.

Curr Opin Chem Biol. 2018 Oct;46:115-122. doi: 10.1016/j.cbpa.2018.07.014. Epub 2018 Jul 27. Review.

6.

Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNACys and elongation factor SelB.

Vargas-Rodriguez O, Englert M, Merkuryev A, Mukai T, Söll D.

RNA Biol. 2018;15(4-5):471-479. doi: 10.1080/15476286.2018.1474074. Epub 2018 Jun 18.

7.

Publisher Correction: Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

Song Y, Zhou H, Vo MN, Shi Y, Nawaz MH, Vargas-Rodriguez O, Diedrich JK, Yates JR 3rd, Kishi S, Musier-Forsyth K, Schimmel P.

Nat Commun. 2018 Mar 13;9(1):1113. doi: 10.1038/s41467-018-03594-1.

8.

Effects of Heterologous tRNA Modifications on the Production of Proteins Containing Noncanonical Amino Acids.

Crnković A, Vargas-Rodriguez O, Merkuryev A, Söll D.

Bioengineering (Basel). 2018 Feb 2;5(1). pii: E11. doi: 10.3390/bioengineering5010011.

9.

Engineering posttranslational proofreading to discriminate nonstandard amino acids.

Kunjapur AM, Stork DA, Kuru E, Vargas-Rodriguez O, Landon M, Söll D, Church GM.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):619-624. doi: 10.1073/pnas.1715137115. Epub 2018 Jan 4.

10.

Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

Song Y, Zhou H, Vo MN, Shi Y, Nawaz MH, Vargas-Rodriguez O, Diedrich JK, Yates JR, Kishi S, Musier-Forsyth K, Schimmel P.

Nat Commun. 2017 Dec 22;8(1):2281. doi: 10.1038/s41467-017-02201-z. Erratum in: Nat Commun. 2018 Mar 13;9(1):1113.

11.

Conformational and chemical selection by a trans-acting editing domain.

Danhart EM, Bakhtina M, Cantara WA, Kuzmishin AB, Ma X, Sanford BL, Vargas-Rodriguez O, Košutić M, Goto Y, Suga H, Nakanishi K, Micura R, Foster MP, Musier-Forsyth K.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6774-E6783. doi: 10.1073/pnas.1703925114. Epub 2017 Aug 2. Erratum in: Proc Natl Acad Sci U S A. 2017 Nov 13;:. Vargas-Rodriguez, Oscar [added].

12.

The central role of tRNA in genetic code expansion.

Reynolds NM, Vargas-Rodriguez O, Söll D, Crnković A.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):3001-3008. doi: 10.1016/j.bbagen.2017.03.012. Epub 2017 Mar 18. Review.

13.

A genomically modified Escherichia coli strain carrying an orthogonal E. coli histidyl-tRNA synthetase•tRNAHis pair.

Englert M, Vargas-Rodriguez O, Reynolds NM, Wang YS, Söll D, Umehara T.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):3009-3015. doi: 10.1016/j.bbagen.2017.03.003. Epub 2017 Mar 10.

14.

Transfer RNAs with novel cloverleaf structures.

Mukai T, Vargas-Rodriguez O, Englert M, Tripp HJ, Ivanova NN, Rubin EM, Kyrpides NC, Söll D.

Nucleic Acids Res. 2017 Mar 17;45(5):2776-2785. doi: 10.1093/nar/gkw898.

15.

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli.

Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5588-97. doi: 10.1073/pnas.1605856113. Epub 2016 Sep 6.

16.

Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation.

Liu Z, Vargas-Rodriguez O, Goto Y, Novoa EM, Ribas de Pouplana L, Suga H, Musier-Forsyth K.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6027-32. doi: 10.1073/pnas.1423664112. Epub 2015 Apr 27.

17.

Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific.

Novoa EM, Vargas-Rodriguez O, Lange S, Goto Y, Suga H, Musier-Forsyth K, Ribas de Pouplana L.

J Biol Chem. 2015 Apr 17;290(16):10495-503. doi: 10.1074/jbc.M115.640060. Epub 2015 Feb 27.

18.

Structural biology: wobble puts RNA on target.

Vargas-Rodriguez O, Musier-Forsyth K.

Nature. 2014 Jun 26;510(7506):480-1. doi: 10.1038/nature13502. Epub 2014 Jun 11. No abstract available.

PMID:
24919145
19.

Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation.

Das M, Vargas-Rodriguez O, Goto Y, Suga H, Musier-Forsyth K.

Nucleic Acids Res. 2014 Apr;42(6):3943-53. doi: 10.1093/nar/gkt1332. Epub 2013 Dec 25.

20.

Exclusive use of trans-editing domains prevents proline mistranslation.

Vargas-Rodriguez O, Musier-Forsyth K.

J Biol Chem. 2013 May 17;288(20):14391-9. doi: 10.1074/jbc.M113.467795. Epub 2013 Apr 5.

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