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Items: 1 to 50 of 218

1.

Correction to: The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.

Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P.

Cell Death Differ. 2019 Sep 5. doi: 10.1038/s41418-019-0405-7. [Epub ahead of print]

PMID:
31488891
2.

A carbonic anhydrase pseudogene sensitizes select Brucella lineages to low CO2 tension.

Varesio LM, Willett JW, Fiebig A, Crosson S.

J Bacteriol. 2019 Sep 3. pii: JB.00509-19. doi: 10.1128/JB.00509-19. [Epub ahead of print]

PMID:
31481543
3.

The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.

Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P.

Cell Death Differ. 2019 Jul 8. doi: 10.1038/s41418-019-0386-6. [Epub ahead of print] Erratum in: Cell Death Differ. 2019 Sep 5;:.

PMID:
31285546
4.

A Proteomic Analysis of GSD-1a in Mouse Livers: Evidence for Metabolic Reprogramming, Inflammation, and Macrophage Polarization.

Cangelosi D, Resaz R, Petretto A, Segalerba D, Ognibene M, Raggi F, Mastracci L, Grillo F, Bosco MC, Varesio L, Sica A, Colombo I, Eva A.

J Proteome Res. 2019 Jul 5;18(7):2965-2978. doi: 10.1021/acs.jproteome.9b00309. Epub 2019 Jun 20.

PMID:
31173686
5.

Regulation of the Erythrobacter litoralis DSM 8509 general stress response by visible light.

Fiebig A, Varesio LM, Alejandro Navarreto X, Crosson S.

Mol Microbiol. 2019 Aug;112(2):442-460. doi: 10.1111/mmi.14310. Epub 2019 Jun 7.

PMID:
31125464
6.

Characterization of high- and low-risk hepatocellular adenomas by magnetic resonance imaging in an animal model of glycogen storage disease type 1A.

Resaz R, Rosa F, Grillo F, Basso L, Segalerba D, Puglisi A, Bosco MC, Mastracci L, Neumaier CE, Varesio L, Eva A.

Dis Model Mech. 2019 Apr 5;12(4). pii: dmm038026. doi: 10.1242/dmm.038026.

7.

Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus.

Herrou J, Willett JW, Fiebig A, Varesio LM, Czyż DM, Cheng JX, Ultee E, Briegel A, Bigelow L, Babnigg G, Kim Y, Crosson S.

Mol Microbiol. 2019 Mar;111(3):637-661. doi: 10.1111/mmi.14178. Epub 2019 Jan 21.

PMID:
30536925
8.

Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration.

Parodi M, Raggi F, Cangelosi D, Manzini C, Balsamo M, Blengio F, Eva A, Varesio L, Pietra G, Moretta L, Mingari MC, Vitale M, Bosco MC.

Front Immunol. 2018 Oct 16;9:2358. doi: 10.3389/fimmu.2018.02358. eCollection 2018.

9.

Favorable prognostic role of tropomodulins in neuroblastoma.

Bettinsoli P, Ferrari-Toninelli G, Bonini SA, Guarienti M, Cangelosi D, Varesio L, Memo M.

Oncotarget. 2018 Jun 5;9(43):27092-27103. doi: 10.18632/oncotarget.25491. eCollection 2018 Jun 5.

10.

CHL1 gene acts as a tumor suppressor in human neuroblastoma.

Ognibene M, Pagnan G, Marimpietri D, Cangelosi D, Cilli M, Benedetti MC, Boldrini R, Garaventa A, Frassoni F, Eva A, Varesio L, Pistoia V, Pezzolo A.

Oncotarget. 2018 May 25;9(40):25903-25921. doi: 10.18632/oncotarget.25403. eCollection 2018 May 25.

11.

Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study.

Berbegall AP, Bogen D, Pötschger U, Beiske K, Bown N, Combaret V, Defferrari R, Jeison M, Mazzocco K, Varesio L, Vicha A, Ash S, Castel V, Coze C, Ladenstein R, Owens C, Papadakis V, Ruud E, Amann G, Sementa AR, Navarro S, Ambros PF, Noguera R, Ambros IM.

Br J Cancer. 2018 May;118(11):1502-1512. doi: 10.1038/s41416-018-0098-6. Epub 2018 May 14.

12.

Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis.

Corrias MV, Parodi S, Tchirkov A, Lammens T, Vicha A, Pasqualini C, Träger C, Yáñez Y, Dallorso S, Varesio L, Luksch R, Laureys G, Valteau-Couanet D, Canete A, Pöetschger U, Ladenstein R, Burchill SA.

Pediatr Blood Cancer. 2018 Jul;65(7):e27052. doi: 10.1002/pbc.27052. Epub 2018 Mar 30.

13.

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.

Depuydt P, Boeva V, Hocking TD, Cannoodt R, Ambros IM, Ambros PF, Asgharzadeh S, Attiyeh EF, Combaret V, Defferrari R, Fischer M, Hero B, Hogarty MD, Irwin MS, Koster J, Kreissman S, Ladenstein R, Lapouble E, Laureys G, London WB, Mazzocco K, Nakagawara A, Noguera R, Ohira M, Park JR, Pötschger U, Theissen J, Tonini GP, Valteau-Couanet D, Varesio L, Versteeg R, Speleman F, Maris JM, Schleiermacher G, De Preter K.

J Natl Cancer Inst. 2018 Oct 1;110(10):1084-1093. doi: 10.1093/jnci/djy022.

14.

Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.

Ognibene M, Cangelosi D, Morini M, Segalerba D, Bosco MC, Sementa AR, Eva A, Varesio L.

PLoS One. 2017 Nov 8;12(11):e0187206. doi: 10.1371/journal.pone.0187206. eCollection 2017.

15.

Regulation of Human Macrophage M1-M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1.

Raggi F, Pelassa S, Pierobon D, Penco F, Gattorno M, Novelli F, Eva A, Varesio L, Giovarelli M, Bosco MC.

Front Immunol. 2017 Sep 7;8:1097. doi: 10.3389/fimmu.2017.01097. eCollection 2017.

16.

Constitutional 3p26.3 terminal microdeletion in an adolescent with neuroblastoma.

Pezzolo A, Sementa AR, Lerone M, Morini M, Ognibene M, Defferrari R, Mazzocco K, Conte M, Gigliotti AR, Garaventa A, Pistoia V, Varesio L.

Cancer Biol Ther. 2017 May 4;18(5):285-289. doi: 10.1080/15384047.2017.1312231. Epub 2017 Apr 12.

17.

First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential.

Balbi C, Piccoli M, Barile L, Papait A, Armirotti A, Principi E, Reverberi D, Pascucci L, Becherini P, Varesio L, Mogni M, Coviello D, Bandiera T, Pozzobon M, Cancedda R, Bollini S.

Stem Cells Transl Med. 2017 May;6(5):1340-1355. doi: 10.1002/sctm.16-0297. Epub 2017 Mar 8.

18.

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Mediators of Anti-Inflammatory Effects: Endorsement of Macrophage Polarization.

Lo Sicco C, Reverberi D, Balbi C, Ulivi V, Principi E, Pascucci L, Becherini P, Bosco MC, Varesio L, Franzin C, Pozzobon M, Cancedda R, Tasso R.

Stem Cells Transl Med. 2017 Mar;6(3):1018-1028. doi: 10.1002/sctm.16-0363. Epub 2017 Jan 31.

19.

Artificial neural network classifier predicts neuroblastoma patients' outcome.

Cangelosi D, Pelassa S, Morini M, Conte M, Bosco MC, Eva A, Sementa AR, Varesio L.

BMC Bioinformatics. 2016 Nov 8;17(Suppl 12):347. doi: 10.1186/s12859-016-1194-3.

20.

Therapeutic Potential of Targeting TREM-1 in Inflammatory Diseases and Cancer.

Bosco MC, Raggi F, Varesio L.

Curr Pharm Des. 2016;22(41):6209-6233. doi: 10.2174/1381612822666160826110539. Review.

PMID:
27568730
21.

Analysis of the Expression and Single-Nucleotide Variant Frequencies of the Butyrophilin-like 2 Gene in Patients With Uveal Melanoma.

Amaro A, Parodi F, Diedrich K, Angelini G, Götz C, Viaggi S, Maric I, Coviello D, Pistillo MP, Morabito A, Mandalà M, Ghiorzo P, Visconti P, Gualco M, Anselmi L, Puzone R, Lanza F, Mosci C, Raggi F, Bosco MC, Varesio L, Zeschnigk M, Spano L, Queirolo P, Pfeffer U.

JAMA Ophthalmol. 2016 Oct 1;134(10):1125-1133. doi: 10.1001/jamaophthalmol.2016.2691.

PMID:
27532663
22.

The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity.

Lazzarini E, Balbi C, Altieri P, Pfeffer U, Gambini E, Canepa M, Varesio L, Bosco MC, Coviello D, Pompilio G, Brunelli C, Cancedda R, Ameri P, Bollini S.

Sci Rep. 2016 Jul 21;6:29994. doi: 10.1038/srep29994.

23.

Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1.

Voena C, Varesio LM, Zhang L, Menotti M, Poggio T, Panizza E, Wang Q, Minero VG, Fagoonee S, Compagno M, Altruda F, Monti S, Chiarle R.

Oncotarget. 2016 May 31;7(22):33316-30. doi: 10.18632/oncotarget.8955.

24.

Regulation of Langerhans cell functions in a hypoxic environment.

Pierobon D, Raggi F, Cambieri I, Pelassa S, Occhipinti S, Cappello P, Novelli F, Musso T, Eva A, Castagnoli C, Varesio L, Giovarelli M, Bosco MC.

J Mol Med (Berl). 2016 Aug;94(8):943-55. doi: 10.1007/s00109-016-1400-9. Epub 2016 Mar 10.

25.

Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.

Ceccon M, Merlo MEB, Mologni L, Poggio T, Varesio LM, Menotti M, Bombelli S, Rigolio R, Manazza AD, Di Giacomo F, Ambrogio C, Giudici G, Casati C, Mastini C, Compagno M, Turner SD, Gambacorti-Passerini C, Chiarle R, Voena C.

Oncogene. 2016 Jul 21;35(29):3854-3865. doi: 10.1038/onc.2015.456. Epub 2015 Dec 14.

26.

Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients.

Stigliani S, Scaruffi P, Lagazio C, Persico L, Carlini B, Varesio L, Morandi F, Morini M, Gigliotti AR, Esposito MR, Viscardi E, Cecinati V, Conte M, Corrias MV.

Oncotarget. 2015 May 30;6(15):13295-308.

27.

Dbl oncogene expression in MCF-10 A epithelial cells disrupts mammary acinar architecture, induces EMT and angiogenic factor secretion.

Vanni C, Ognibene M, Finetti F, Mancini P, Cabodi S, Segalerba D, Torrisi MR, Donnini S, Bosco MC, Varesio L, Eva A.

Cell Cycle. 2015;14(9):1426-37. doi: 10.1080/15384101.2015.1021516.

28.

The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma.

Amoroso F, Capece M, Rotondo A, Cangelosi D, Ferracin M, Franceschini A, Raffaghello L, Pistoia V, Varesio L, Adinolfi E.

Oncogene. 2015 Oct 8;34(41):5240-51. doi: 10.1038/onc.2014.444. Epub 2015 Jan 26.

PMID:
25619831
29.

Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling.

Lee S, Rahnenführer J, Lang M, De Preter K, Mestdagh P, Koster J, Versteeg R, Stallings RL, Varesio L, Asgharzadeh S, Schulte JH, Fielitz K, Schwermer M, Morik K, Schramm A.

PLoS One. 2014 Oct 8;9(10):e108818. doi: 10.1371/journal.pone.0108818. eCollection 2014.

30.

Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-α deficiency.

Resaz R, Vanni C, Segalerba D, Sementa AR, Mastracci L, Grillo F, Murgia D, Bosco MC, Chou JY, Barbieri O, Varesio L, Eva A.

Dis Model Mech. 2014 Sep;7(9):1083-91. doi: 10.1242/dmm.014878.

31.

Use of Attribute Driven Incremental Discretization and Logic Learning Machine to build a prognostic classifier for neuroblastoma patients.

Cangelosi D, Muselli M, Parodi S, Blengio F, Becherini P, Versteeg R, Conte M, Varesio L.

BMC Bioinformatics. 2014;15 Suppl 5:S4. doi: 10.1186/1471-2105-15-S5-S4. Epub 2014 May 6.

32.

A digital repository with an extensible data model for biobanking and genomic analysis management.

Izzo M, Mortola F, Arnulfo G, Fato MM, Varesio L.

BMC Genomics. 2014;15 Suppl 3:S3. doi: 10.1186/1471-2164-15-S3-S3. Epub 2014 May 6.

33.

Identification of a novel mouse Dbl proto-oncogene splice variant: evidence that SEC14 domain is involved in GEF activity regulation.

Ognibene M, Vanni C, Blengio F, Segalerba D, Mancini P, De Marco P, Torrisi MR, Bosco MC, Varesio L, Eva A.

Gene. 2014 Mar 10;537(2):220-9. doi: 10.1016/j.gene.2013.12.064. Epub 2014 Jan 9.

PMID:
24412292
34.

Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages.

Raggi F, Blengio F, Eva A, Pende D, Varesio L, Bosco MC.

Innate Immun. 2014 Oct;20(7):721-34. doi: 10.1177/1753425913507095. Epub 2013 Oct 16.

PMID:
24131792
35.

Spermine metabolism and radiation-derived reactive oxygen species for future therapeutic implications in cancer: an additive or adaptive response.

Amendola R, Cervelli M, Tempera G, Fratini E, Varesio L, Mariottini P, Agostinelli E.

Amino Acids. 2014 Mar;46(3):487-98. doi: 10.1007/s00726-013-1579-9. Epub 2013 Sep 3. Review.

PMID:
23999645
36.

Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC.

Balsamo M, Manzini C, Pietra G, Raggi F, Blengio F, Mingari MC, Varesio L, Moretta L, Bosco MC, Vitale M.

Eur J Immunol. 2013 Oct;43(10):2756-64. doi: 10.1002/eji.201343448. Epub 2013 Aug 5.

37.

Logic Learning Machine creates explicit and stable rules stratifying neuroblastoma patients.

Cangelosi D, Blengio F, Versteeg R, Eggert A, Garaventa A, Gambini C, Conte M, Eva A, Muselli M, Varesio L.

BMC Bioinformatics. 2013;14 Suppl 7:S12. doi: 10.1186/1471-2105-14-S7-S12. Epub 2013 Apr 22.

38.

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression.

Pierobon D, Bosco MC, Blengio F, Raggi F, Eva A, Filippi M, Musso T, Novelli F, Cappello P, Varesio L, Giovarelli M.

Eur J Immunol. 2013 Apr;43(4):949-66. doi: 10.1002/eji.201242709. Epub 2013 Mar 6.

39.

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.

Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH.

Nat Genet. 2012 Nov;44(11):1199-206. doi: 10.1038/ng.2436. Epub 2012 Oct 7.

PMID:
23042116
40.

The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform.

Cattelani S, Ferrari-Amorotti G, Galavotti S, Defferrari R, Tanno B, Cialfi S, Vergalli J, Fragliasso V, Guerzoni C, Manzotti G, Soliera AR, Menin C, Bertorelle R, McDowell HP, Inserra A, Belli ML, Varesio L, Tweddle D, Tonini GP, Altavista P, Dominici C, Raschellà G, Calabretta B.

Neoplasia. 2012 Jul;14(7):634-43.

41.

Dendritic cell reprogramming by the hypoxic environment.

Bosco MC, Varesio L.

Immunobiology. 2012 Dec;217(12):1241-9. doi: 10.1016/j.imbio.2012.07.023. Epub 2012 Jul 27.

PMID:
22901977
42.

Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway.

Petecchia L, Sabatini F, Usai C, Caci E, Varesio L, Rossi GA.

Lab Invest. 2012 Aug;92(8):1140-8.

43.

Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome.

Cornero A, Acquaviva M, Fardin P, Versteeg R, Schramm A, Eva A, Bosco MC, Blengio F, Barzaghi S, Varesio L.

BMC Bioinformatics. 2012 Mar 28;13 Suppl 4:S13. doi: 10.1186/1471-2105-13-S4-S13.

44.

The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells.

Blengio F, Raggi F, Pierobon D, Cappello P, Eva A, Giovarelli M, Varesio L, Bosco MC.

Immunobiology. 2013 Jan;218(1):76-89. doi: 10.1016/j.imbio.2012.02.002. Epub 2012 Feb 10.

PMID:
22465745
45.

The tumor suppressor hamartin enhances Dbl protein transforming activity through interaction with ezrin.

Ognibene M, Vanni C, Segalerba D, Mancini P, Merello E, Torrisi MR, Bosco MC, Varesio L, Eva A.

J Biol Chem. 2011 Aug 26;286(34):29973-83. doi: 10.1074/jbc.M111.270785. Epub 2011 Jun 28.

46.

Treatment of newborn G6pc(-/-) mice with bone marrow-derived myelomonocytes induces liver repair.

Resaz R, Emionite L, Vanni C, Astigiano S, Puppo M, Lavieri R, Segalerba D, Pezzolo A, Bosco MC, Oberto A, Eva C, Chou JY, Varesio L, Barbieri O, Eva A.

J Hepatol. 2011 Dec;55(6):1263-71. doi: 10.1016/j.jhep.2011.02.033. Epub 2011 Apr 13.

47.

Hypoxia: a double-edged sword of immunity.

Sica A, Melillo G, Varesio L.

J Mol Med (Berl). 2011 Jul;89(7):657-65. doi: 10.1007/s00109-011-0724-8. Epub 2011 Feb 19. Review.

PMID:
21336851
48.

High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.

Ognibene M, Barbieri O, Vanni C, Mastracci L, Astigiano S, Emionite L, Salani B, Fedele M, Resaz R, Tenca C, Fais F, Sabatini F, De Santanna A, Altruda F, Varesio L, Hirsch E, Eva A.

J Mol Med (Berl). 2011 May;89(5):493-504. doi: 10.1007/s00109-010-0712-4. Epub 2011 Jan 11.

PMID:
21221514
49.

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.

Bosco MC, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, Eva A, Novelli F, Cappello P, Giovarelli M, Varesio L.

Blood. 2011 Mar 3;117(9):2625-39. doi: 10.1182/blood-2010-06-292136. Epub 2010 Dec 10.

50.

Identification of multiple hypoxia signatures in neuroblastoma cell lines by l1-l2 regularization and data reduction.

Fardin P, Cornero A, Barla A, Mosci S, Acquaviva M, Rosasco L, Gambini C, Verri A, Varesio L.

J Biomed Biotechnol. 2010;2010:878709. doi: 10.1155/2010/878709. Epub 2010 Jun 28.

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