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Items: 1 to 50 of 119

1.

Biomarkers in Vestibular Schwannoma-Associated Hearing Loss.

Lassaletta L, Calvino M, Morales-Puebla JM, Lapunzina P, Rodriguez-de la Rosa L, Varela-Nieto I, Martinez-Glez V.

Front Neurol. 2019 Sep 18;10:978. doi: 10.3389/fneur.2019.00978. eCollection 2019. Review.

2.

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity.

Cervantes B, Arana L, Murillo-Cuesta S, Bruno M, Alkorta I, Varela-Nieto I.

J Clin Med. 2019 Sep 14;8(9). pii: E1464. doi: 10.3390/jcm8091464.

3.

TGFβ2-induced senescence during early inner ear development.

Gibaja A, Aburto MR, Pulido S, Collado M, Hurle JM, Varela-Nieto I, Magariños M.

Sci Rep. 2019 Apr 11;9(1):5912. doi: 10.1038/s41598-019-42040-0.

4.

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.

Celaya AM, Sánchez-Pérez I, Bermúdez-Muñoz JM, Rodríguez-de la Rosa L, Pintado-Berninches L, Perona R, Murillo-Cuesta S, Varela-Nieto I.

Elife. 2019 Apr 2;8. pii: e39159. doi: 10.7554/eLife.39159.

5.

Neuroglial Involvement in Abnormal Glutamate Transport in the Cochlear Nuclei of the Igf1 -/- Mouse.

Fuentes-Santamaría V, Alvarado JC, Rodríguez-de la Rosa L, Juiz JM, Varela-Nieto I.

Front Cell Neurosci. 2019 Mar 1;13:67. doi: 10.3389/fncel.2019.00067. eCollection 2019.

6.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.

Partearroyo T, Murillo-Cuesta S, Vallecillo N, Bermúdez-Muñoz JM, Rodríguez-de la Rosa L, Mandruzzato G, Celaya AM, Zeisel SH, Pajares MA, Varela-Moreiras G, Varela-Nieto I.

FASEB J. 2019 May;33(5):5942-5956. doi: 10.1096/fj.201801533R. Epub 2019 Feb 12.

7.

Complementary and distinct roles of autophagy, apoptosis and senescence during early inner ear development.

Varela-Nieto I, Palmero I, Magariños M.

Hear Res. 2019 May;376:86-96. doi: 10.1016/j.heares.2019.01.014. Epub 2019 Jan 23. Review.

PMID:
30711386
8.

Editorial: Hormones and Neural Aging: Lessons From Experimental Models.

Varela-Nieto I, Chowen JA, García-Segura LM.

Front Aging Neurosci. 2018 Nov 15;10:374. doi: 10.3389/fnagi.2018.00374. eCollection 2018. No abstract available.

9.

Modelling physical resilience in ageing mice.

Schosserer M, Banks G, Dogan S, Dungel P, Fernandes A, Marolt Presen D, Matheu A, Osuchowski M, Potter P, Sanfeliu C, Tuna BG, Varela-Nieto I, Bellantuono I.

Mech Ageing Dev. 2019 Jan;177:91-102. doi: 10.1016/j.mad.2018.10.001. Epub 2018 Oct 2. Review.

10.

Tackling frailty and functional decline: Background of the action group A3 of the European innovation partnership for active and healthy ageing.

Cano A, Dargent G, Carriazo A, López-Samaniego L, Apostolo J, Campos E, Holland C, Varela-Nieto I, Luz Sánchez-Sánchez M, Illario M, Iaccarino G, Roller RE, Goossens E, Vollenbroek-Hutten M, Pais S, Schena F, Musian D, Alvino S, Maggio M, Liotta G, Ussai S, Orfila F, O'Caoimh R, Paul C, Pazzi S, Romano V, Obbia P.

Maturitas. 2018 Sep;115:69-73. doi: 10.1016/j.maturitas.2018.06.009. Epub 2018 Jun 20. Review.

PMID:
30049350
11.

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

Wesdorp M, Murillo-Cuesta S, Peters T, Celaya AM, Oonk A, Schraders M, Oostrik J, Gomez-Rosas E, Beynon AJ, Hartel BP, Okkersen K, Koenen HJPM, Weeda J, Lelieveld S, Voermans NC, Joosten I, Hoyng CB, Lichtner P, Kunst HPM, Feenstra I, de Bruijn SE; DOOFNL Consortium, Admiraal RJC, Yntema HG, van Wijk E, Del Castillo I, Serra P, Varela-Nieto I, Pennings RJE, Kremer H.

Am J Hum Genet. 2018 Jul 5;103(1):74-88. doi: 10.1016/j.ajhg.2018.05.011. Epub 2018 Jun 28.

12.

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss.

Espino Guarch M, Font-Llitjós M, Murillo-Cuesta S, Errasti-Murugarren E, Celaya AM, Girotto G, Vuckovic D, Mezzavilla M, Vilches C, Bodoy S, Sahún I, González L, Prat E, Zorzano A, Dierssen M, Varela-Nieto I, Gasparini P, Palacín M, Nunes V.

Elife. 2018 Jan 22;7. pii: e31511. doi: 10.7554/eLife.31511.

13.

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss.

Rodríguez-de la Rosa L, Lassaletta L, Calvino M, Murillo-Cuesta S, Varela-Nieto I.

Front Aging Neurosci. 2017 Dec 12;9:411. doi: 10.3389/fnagi.2017.00411. eCollection 2017. Review.

14.

The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea.

García-Alcántara F, Murillo-Cuesta S, Pulido S, Bermúdez-Muñoz JM, Martínez-Vega R, Milo M, Varela-Nieto I, Rivera T.

Hear Res. 2018 Feb;358:10-21. doi: 10.1016/j.heares.2017.12.004. Epub 2017 Dec 14.

PMID:
29304389
15.

Usefulness of Electrical Auditory Brainstem Responses to Assess the Functionality of the Cochlear Nerve Using an Intracochlear Test Electrode.

Lassaletta L, Polak M, Huesers J, Díaz-Gómez M, Calvino M, Varela-Nieto I, Gavilán J.

Otol Neurotol. 2017 Dec;38(10):e413-e420. doi: 10.1097/MAO.0000000000001584.

PMID:
29076926
16.

Autophagy in the Vertebrate Inner Ear.

Magariños M, Pulido S, Aburto MR, de Iriarte Rodríguez R, Varela-Nieto I.

Front Cell Dev Biol. 2017 May 26;5:56. doi: 10.3389/fcell.2017.00056. eCollection 2017. Review.

17.

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss.

Partearroyo T, Vallecillo N, Pajares MA, Varela-Moreiras G, Varela-Nieto I.

Front Mol Neurosci. 2017 Apr 25;10:107. doi: 10.3389/fnmol.2017.00107. eCollection 2017. Review.

18.

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection.

Murillo-Cuesta S, Vallecillo N, Cediel R, Celaya AM, Lassaletta L, Varela-Nieto I, Contreras J.

J Vis Exp. 2017 Mar 8;(121). doi: 10.3791/54951.

19.

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice.

Martínez-Vega R, Murillo-Cuesta S, Partearroyo T, Varela-Moreiras G, Varela-Nieto I, Pajares MA.

Front Aging Neurosci. 2016 Aug 31;8:209. doi: 10.3389/fnagi.2016.00209. eCollection 2016.

20.

Autophagy resolves early retinal inflammation in Igf1-deficient mice.

Arroba AI, Rodríguez-de la Rosa L, Murillo-Cuesta S, Vaquero-Villanueva L, Hurlé JM, Varela-Nieto I, Valverde ÁM.

Dis Model Mech. 2016 Sep 1;9(9):965-74. doi: 10.1242/dmm.026344. Epub 2016 Jul 21.

21.

Frailty in mouse ageing: A conceptual approach.

von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, Cardoso AL, Novella S, Lepperdinger G, Trendelenburg AU, van Os R.

Mech Ageing Dev. 2016 Dec;160:34-40. doi: 10.1016/j.mad.2016.07.004. Epub 2016 Jul 18. Review.

22.

Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.

Buniello A, Ingham NJ, Lewis MA, Huma AC, Martinez-Vega R, Varela-Nieto I, Vizcay-Barrena G, Fleck RA, Houston O, Bardhan T, Johnson SL, White JK, Yuan H, Marcotti W, Steel KP.

EMBO Mol Med. 2016 Mar 1;8(3):191-207. doi: 10.15252/emmm.201505523.

23.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de Figueiredo RC, de la Fuente J, De Martino L, De Matteis A, De Meyer GR, De Milito A, De Santi M, de Souza W, De Tata V, De Zio D, Debnath J, Dechant R, Decuypere JP, Deegan S, Dehay B, Del Bello B, Del Re DP, Delage-Mourroux R, Delbridge LM, Deldicque L, Delorme-Axford E, Deng Y, Dengjel J, Denizot M, Dent P, Der CJ, Deretic V, Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Di Domenico F, Di Nardo A, Di Paola S, Di Pietro A, Di Renzo L, DiAntonio A, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dickey CA, Dickson RC, Diederich M, Digard P, Dikic I, Dinesh-Kumar SP, Ding C, Ding WX, Ding Z, Dini L, Distler JH, Diwan A, Djavaheri-Mergny M, Dmytruk K, Dobson RC, Doetsch V, Dokladny K, Dokudovskaya S, Donadelli M, Dong XC, Dong X, Dong Z, Donohue TM Jr, Doran KS, D'Orazi G, Dorn GW 2nd, Dosenko V, Dridi S, Drucker L, Du J, Du LL, Du L, du Toit A, Dua P, Duan L, Duann P, Dubey VK, Duchen MR, Duchosal MA, Duez H, Dugail I, Dumit VI, Duncan MC, Dunlop EA, Dunn WA Jr, Dupont N, Dupuis L, Durán RV, Durcan TM, Duvezin-Caubet S, Duvvuri U, Eapen V, Ebrahimi-Fakhari D, Echard A, Eckhart L, Edelstein CL, Edinger AL, Eichinger L, Eisenberg T, Eisenberg-Lerner A, Eissa NT, El-Deiry WS, El-Khoury V, Elazar Z, Eldar-Finkelman H, Elliott CJ, Emanuele E, Emmenegger U, Engedal N, Engelbrecht AM, Engelender S, Enserink JM, Erdmann R, Erenpreisa J, Eri R, Eriksen JL, Erman A, Escalante R, Eskelinen EL, Espert L, Esteban-Martínez L, Evans TJ, Fabri M, Fabrias G, Fabrizi C, Facchiano A, Færgeman NJ, Faggioni A, Fairlie WD, Fan C, Fan D, Fan J, Fang S, Fanto M, Fanzani A, Farkas T, Faure M, Favier FB, Fearnhead H, Federici M, Fei E, Felizardo TC, Feng H, Feng Y, Feng Y, Ferguson TA, Fernández ÁF, Fernandez-Barrena MG, Fernandez-Checa JC, Fernández-López A, Fernandez-Zapico ME, Feron O, Ferraro E, Ferreira-Halder CV, Fesus L, Feuer R, Fiesel FC, Filippi-Chiela EC, Filomeni G, Fimia GM, Fingert JH, Finkbeiner S, Finkel T, Fiorito F, Fisher PB, Flajolet M, Flamigni F, Florey O, Florio S, Floto RA, Folini M, Follo C, Fon EA, Fornai F, Fortunato F, Fraldi A, Franco R, Francois A, François A, Frankel LB, Fraser ID, Frey N, Freyssenet DG, Frezza C, Friedman SL, Frigo DE, Fu D, Fuentes JM, Fueyo J, Fujitani Y, Fujiwara Y, Fujiya M, Fukuda M, Fulda S, Fusco C, Gabryel B, Gaestel M, Gailly P, Gajewska M, Galadari S, Galili G, Galindo I, Galindo MF, Galliciotti G, Galluzzi L, Galluzzi L, Galy V, Gammoh N, Gandy S, Ganesan AK, Ganesan S, Ganley IG, Gannagé M, Gao FB, Gao F, Gao JX, García Nannig L, García Véscovi E, Garcia-Macía M, Garcia-Ruiz C, Garg AD, Garg PK, Gargini R, Gassen NC, Gatica D, Gatti E, Gavard J, Gavathiotis E, Ge L, Ge P, Ge S, Gean PW, Gelmetti V, Genazzani AA, Geng J, Genschik P, Gerner L, Gestwicki JE, Gewirtz DA, Ghavami S, Ghigo E, Ghosh D, Giammarioli AM, Giampieri F, Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Giordano A, Giorgini F, Giovannetti E, Girardin SE, Gispert S, Giuliano S, Gladson CL, Glavic A, Gleave M, Godefroy N, Gogal RM Jr, Gokulan K, Goldman GH, Goletti D, Goligorsky MS, Gomes AV, Gomes LC, Gomez H, Gomez-Manzano C, Gómez-Sánchez R, Gonçalves DA, Goncu E, Gong Q, Gongora C, Gonzalez CB, Gonzalez-Alegre P, Gonzalez-Cabo P, González-Polo RA, Goping IS, Gorbea C, Gorbunov NV, Goring DR, Gorman AM, Gorski SM, Goruppi S, Goto-Yamada S, Gotor C, Gottlieb RA, Gozes I, Gozuacik D, Graba Y, Graef M, Granato GE, Grant GD, Grant S, Gravina GL, Green DR, Greenhough A, Greenwood MT, Grimaldi B, Gros F, Grose C, Groulx JF, Gruber F, Grumati P, Grune T, Guan JL, Guan KL, Guerra B, Guillen C, Gulshan K, Gunst J, Guo C, Guo L, Guo M, Guo W, Guo XG, Gust AA, Gustafsson ÅB, Gutierrez E, Gutierrez MG, Gwak HS, Haas A, Haber JE, Hadano S, Hagedorn M, Hahn DR, Halayko AJ, Hamacher-Brady A, Hamada K, Hamai A, Hamann A, Hamasaki M, Hamer I, Hamid Q, Hammond EM, Han F, Han W, Handa JT, Hanover JA, Hansen M, Harada M, Harhaji-Trajkovic L, Harper JW, Harrath AH, 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C-Raf deficiency leads to hearing loss and increased noise susceptibility.

de Iriarte Rodríguez R, Magariños M, Pfeiffer V, Rapp UR, Varela-Nieto I.

Cell Mol Life Sci. 2015 Oct;72(20):3983-98. doi: 10.1007/s00018-015-1919-x. Epub 2015 May 15.

33.

Transforming growth factor β1 inhibition protects from noise-induced hearing loss.

Murillo-Cuesta S, Rodríguez-de la Rosa L, Contreras J, Celaya AM, Camarero G, Rivera T, Varela-Nieto I.

Front Aging Neurosci. 2015 Mar 20;7:32. doi: 10.3389/fnagi.2015.00032. eCollection 2015.

34.

Swept-sine noise-induced damage as a hearing loss model for preclinical assays.

Sanz L, Murillo-Cuesta S, Cobo P, Cediel-Algovia R, Contreras J, Rivera T, Varela-Nieto I, Avendaño C.

Front Aging Neurosci. 2015 Feb 16;7:7. doi: 10.3389/fnagi.2015.00007. eCollection 2015. Erratum in: Front Aging Neurosci. 2015;7:79.

35.

Targeting cholesterol homeostasis to fight hearing loss: a new perspective.

Malgrange B, Varela-Nieto I, de Medina P, Paillasse MR.

Front Aging Neurosci. 2015 Jan 29;7:3. doi: 10.3389/fnagi.2015.00003. eCollection 2015. Review.

36.

Erratum to: IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei.

Fuentes-Santamaría V, Alvarado JC, Rodríguez-de la Rosa L, Murillo-Cuesta S, Contreras J, Juiz JM, Varela-Nieto I.

Brain Struct Funct. 2016 Mar;221(2):1205. doi: 10.1007/s00429-014-0945-z. No abstract available.

PMID:
25416135
37.

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.

Martínez-Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel SH, Martínez-Álvarez C, Varela-Moreiras G, Varela-Nieto I, Pajares MA.

FASEB J. 2015 Feb;29(2):418-32. doi: 10.1096/fj.14-259283. Epub 2014 Nov 10.

38.

IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei.

Fuentes-Santamaría V, Alvarado JC, Rodríguez-de la Rosa L, Murillo-Cuesta S, Contreras J, Juiz JM, Varela-Nieto I.

Brain Struct Funct. 2016 Mar;221(2):709-34. doi: 10.1007/s00429-014-0934-2. Epub 2014 Nov 7. Erratum in: Brain Struct Funct. 2016 Mar;221(2):1205.

PMID:
25378055
39.

Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r fl/fl double transgenic mice.

López IP, Rodriguez-de la Rosa L, Pais RS, Piñeiro-Hermida S, Torrens R, Contreras J, Varela-Nieto I, Pichel JG.

Transgenic Res. 2015 Apr;24(2):279-94. doi: 10.1007/s11248-014-9837-5. Epub 2014 Sep 20.

PMID:
25238791
40.

Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex.

García-Díaz B, Riquelme R, Varela-Nieto I, Jiménez AJ, de Diego I, Gómez-Conde AI, Matas-Rico E, Aguirre JÁ, Chun J, Pedraza C, Santín LJ, Fernández O, Rodríguez de Fonseca F, Estivill-Torrús G.

Brain Struct Funct. 2015 Nov;220(6):3701-20. doi: 10.1007/s00429-014-0885-7. Epub 2014 Sep 17.

PMID:
25226845
41.

Treatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice.

Rodríguez-de la Rosa L, López-Herradón A, Portal-Núñez S, Murillo-Cuesta S, Lozano D, Cediel R, Varela-Nieto I, Esbrit P.

PLoS One. 2014 Feb 4;9(2):e87536. doi: 10.1371/journal.pone.0087536. eCollection 2014.

42.

Programmed cell senescence during mammalian embryonic development.

Muñoz-Espín D, Cañamero M, Maraver A, Gómez-López G, Contreras J, Murillo-Cuesta S, Rodríguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M.

Cell. 2013 Nov 21;155(5):1104-18. doi: 10.1016/j.cell.2013.10.019. Epub 2013 Nov 14.

43.

IGF-I deficiency and hearing loss: molecular clues and clinical implications.

Varela-Nieto I, Murillo-Cuesta S, Rodríguez-de la Rosa L, Lassatetta L, Contreras J.

Pediatr Endocrinol Rev. 2013 Jul;10(4):460-72. Review.

PMID:
23957197
44.

Early development of the vertebrate inner ear.

Magariños M, Contreras J, Aburto MR, Varela-Nieto I.

Anat Rec (Hoboken). 2012 Nov;295(11):1775-90. doi: 10.1002/ar.22575. Epub 2012 Oct 8. Review.

45.

Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation.

Aburto MR, Sánchez-Calderón H, Hurlé JM, Varela-Nieto I, Magariños M.

Cell Death Dis. 2012 Oct 4;3:e394. doi: 10.1038/cddis.2012.132.

46.

Age-related functional and structural retinal modifications in the Igf1-/- null mouse.

Rodriguez-de la Rosa L, Fernandez-Sanchez L, Germain F, Murillo-Cuesta S, Varela-Nieto I, de la Villa P, Cuenca N.

Neurobiol Dis. 2012 May;46(2):476-85. doi: 10.1016/j.nbd.2012.02.013. Epub 2012 Feb 28.

PMID:
22402333
47.

AKT signaling mediates IGF-I survival actions on otic neural progenitors.

Aburto MR, Magariños M, Leon Y, Varela-Nieto I, Sanchez-Calderon H.

PLoS One. 2012;7(1):e30790. doi: 10.1371/journal.pone.0030790. Epub 2012 Jan 23.

48.

Drug delivery to the inner ear: strategies and their therapeutic implications for sensorineural hearing loss.

Rivera T, Sanz L, Camarero G, Varela-Nieto I.

Curr Drug Deliv. 2012 May;9(3):231-42. Review.

PMID:
22283653
49.

Autophagy during vertebrate development.

Aburto MR, Hurlé JM, Varela-Nieto I, Magariños M.

Cells. 2012 Aug 2;1(3):428-48. doi: 10.3390/cells1030428.

50.

Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function.

Murillo-Cuesta S, Camarero G, González-Rodríguez A, De La Rosa LR, Burks DJ, Avendaño C, Valverde AM, Varela-Nieto I.

Mol Med. 2012 Mar 30;18:260-9. doi: 10.2119/molmed.2011.00328.

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