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Items: 11

1.

Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.

Gil-Garcia M, Bañó-Polo M, Varejão N, Jamroz M, Kuriata A, Díaz-Caballero M, Lascorz J, Morel B, Navarro S, Reverter D, Kmiecik S, Ventura S.

Mol Pharm. 2018 Sep 4;15(9):3846-3859. doi: 10.1021/acs.molpharmaceut.8b00341. Epub 2018 Aug 6.

PMID:
30036481
2.

DNA activates the Nse2/Mms21 SUMO E3 ligase in the Smc5/6 complex.

Varejão N, Ibars E, Lascorz J, Colomina N, Torres-Rosell J, Reverter D.

EMBO J. 2018 Jun 15;37(12). pii: e98306. doi: 10.15252/embj.201798306. Epub 2018 May 16.

PMID:
29769404
3.

Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.

Varejão N, De-Andrade RA, Almeida RV, Anobom CD, Foguel D, Reverter D.

Structure. 2018 Feb 6;26(2):199-208.e3. doi: 10.1016/j.str.2017.12.004. Epub 2018 Jan 4.

PMID:
29307486
4.

pCramoll and rCramoll lectins induce cell death in human prostate adenocarcinoma (PC-3) cells by impairment of mitochondrial homeostasis.

de Oliveira Figueirôa E, Aranda-Souza MÂ, Varejão N, Rossato FA, Costa RAP, Figueira TR, da Silva LCN, Castilho RF, Vercesi AE, Dos Santos Correia MT.

Toxicol In Vitro. 2017 Sep;43:40-46. doi: 10.1016/j.tiv.2017.05.016. Epub 2017 May 25.

5.

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.

Sant'Anna R, Almeida MR, Varejāo N, Gallego P, Esperante S, Ferreira P, Pereira-Henriques A, Palhano FL, de Carvalho M, Foguel D, Reverter D, Saraiva MJ, Ventura S.

Sci Rep. 2017 Mar 24;7:44709. doi: 10.1038/srep44709.

6.

Encapsulation into Stealth Liposomes Enhances the Antitumor Action of Recombinant Cratylia mollis Lectin Expressed in Escherichia coli.

da Cunha CR, da Silva LC, Almeida FJ, Ferraz MS, Varejão N, Cartaxo MF, de Miranda RC, de Aguiar FC Jr, Santos NP, Coelho LC, Santos-Magalhães NS, Correia MT.

Front Microbiol. 2016 Sep 16;7:1355. eCollection 2016.

7.

The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.

Sant'Anna R, Braga C, Varejão N, Pimenta KM, Graña-Montes R, Alves A, Cortines J, Cordeiro Y, Ventura S, Foguel D.

J Biol Chem. 2014 Oct 10;289(41):28324-37. doi: 10.1074/jbc.M114.563981. Epub 2014 Aug 1.

8.

Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy.

Ferreira P, Sant'Anna R, Varejão N, Lima C, Novis S, Barbosa RV, Caldeira CM, Rumjanek FD, Ventura S, Cruz MW, Foguel D.

PLoS One. 2013 Dec 17;8(12):e82484. doi: 10.1371/journal.pone.0082484. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/2ea264c2-d70c-4a2e-b877-c084dc3a49db. Sant'Anna, Oliveira [corrected to Sant'Anna, Ricardo].

9.

Characterization of the unfolding process of the tetrameric and dimeric forms of Cratylia mollis seed lectin (CRAMOLL 1): effects of natural fragmentation on protein stability.

Varejão N, Correia MT, Foguel D.

Biochemistry. 2011 Aug 30;50(34):7330-40. doi: 10.1021/bi200320x. Epub 2011 Aug 3.

PMID:
21790141
10.

Heterologous expression and purification of a biologically active legume lectin from Cratylia mollis seeds (CRAMOLL 1).

Varejão N, Almeida Mda S, De Cicco NN, Atella GC, Coelho LC, Correia MA, Foguel D.

Biochim Biophys Acta. 2010 Sep;1804(9):1917-24. doi: 10.1016/j.bbapap.2010.06.004. Epub 2010 Jun 9.

PMID:
20538076
11.

[Intramuscular use of 10 percent sodium thiopental].

Fortes JD, Giordano HP, Varejão N.

Rev Bras Anestesiol. 1966 Oct-Dec;16(4):444-6. Portuguese. No abstract available.

PMID:
6011880

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