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Items: 47

1.

Quantification of Melanosome Transfer Using Immunofluorescence Microscopy and Automated Image Analysis.

Sridharan A, John Lim SY, Wright GD, Vardy LA.

Methods Mol Biol. 2019 Jun 4. doi: 10.1007/7651_2019_241. [Epub ahead of print]

PMID:
31161578
2.

Polyamine Regulator AMD1 Promotes Cell Migration in Epidermal Wound Healing.

Lim HK, Rahim AB, Leo VI, Das S, Lim TC, Uemura T, Igarashi K, Common J, Vardy LA.

J Invest Dermatol. 2018 Dec;138(12):2653-2665. doi: 10.1016/j.jid.2018.05.029. Epub 2018 Jun 12.

PMID:
29906410
3.

MINDY1 Is a Downstream Target of the Polyamines and Promotes Embryonic Stem Cell Self-Renewal.

James C, Zhao TY, Rahim A, Saxena P, Muthalif NA, Uemura T, Tsuneyoshi N, Ong S, Igarashi K, Lim CY, Dunn NR, Vardy LA.

Stem Cells. 2018 Aug;36(8):1170-1178. doi: 10.1002/stem.2830. Epub 2018 Apr 22.

PMID:
29644784
4.

5-Methylcytosine RNA Methylation in Arabidopsis Thaliana.

Cui X, Liang Z, Shen L, Zhang Q, Bao S, Geng Y, Zhang B, Leo V, Vardy LA, Lu T, Gu X, Yu H.

Mol Plant. 2017 Nov 6;10(11):1387-1399. doi: 10.1016/j.molp.2017.09.013. Epub 2017 Sep 28.

5.

MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease.

Martinez EC, Lilyanna S, Wang P, Vardy LA, Jiang X, Armugam A, Jeyaseelan K, Richards AM.

J Mol Cell Cardiol. 2017 Nov;112:27-39. doi: 10.1016/j.yjmcc.2017.08.013. Epub 2017 Sep 1.

PMID:
28865712
6.

Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells.

Itahana Y, Zhang J, Göke J, Vardy LA, Han R, Iwamoto K, Cukuroglu E, Robson P, Pouladi MA, Colman A, Itahana K.

Sci Rep. 2016 Jun 27;6:28112. doi: 10.1038/srep28112.

7.

Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells.

Carlevaro-Fita J, Rahim A, Guigó R, Vardy LA, Johnson R.

RNA. 2016 Jun;22(6):867-82. doi: 10.1261/rna.053561.115. Epub 2016 Apr 18.

8.

Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation.

Wong QW, Vaz C, Lee QY, Zhao TY, Luo R, Archer SK, Preiss T, Tanavde V, Vardy LA.

PLoS One. 2016 Jan 22;11(1):e0143235. doi: 10.1371/journal.pone.0143235. eCollection 2016.

9.

Analysis of mRNA Translation Rate in Mouse Embryonic Stem Cells.

Rahim AB, Vardy LA.

Methods Mol Biol. 2016;1341:143-55. doi: 10.1007/7651_2015_233.

PMID:
26084596
10.

Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress.

Giannakakis A, Zhang J, Jenjaroenpun P, Nama S, Zainolabidin N, Aau MY, Yarmishyn AA, Vaz C, Ivshina AV, Grinchuk OV, Voorhoeve M, Vardy LA, Sampath P, Kuznetsov VA, Kurochkin IV, Guccione E.

Sci Rep. 2015 May 29;5:9737. doi: 10.1038/srep09737.

11.

Natriuretic peptide receptor 3 (NPR3) is regulated by microRNA-100.

Wong LL, Wee AS, Lim JY, Ng JY, Chong JP, Liew OW, Lilyanna S, Martinez EC, Ackers-Johnson MA, Vardy LA, Armugam A, Jeyaseelan K, Ng TP, Lam CS, Foo RS, Richards AM, Chen YT.

J Mol Cell Cardiol. 2015 May;82:13-21. doi: 10.1016/j.yjmcc.2015.02.019. Epub 2015 Feb 28.

PMID:
25736855
12.

Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation.

Tan SM, Altschuler G, Zhao TY, Ang HS, Yang H, Lim B, Vardy L, Hide W, Thomson AM, Lareu RR.

Nucleic Acids Res. 2014 Jul;42(12):7997-8007. doi: 10.1093/nar/gku430. Epub 2014 May 23.

13.

RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors.

Wong QW, Li J, Ng SR, Lim SG, Yang H, Vardy LA.

RNA Biol. 2014;11(1):33-41. doi: 10.4161/rna.27427. Epub 2013 Dec 20.

14.

Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.

Ramot Y, Vardy LA.

Exp Dermatol. 2013 Nov;22(11):697-8. doi: 10.1111/exd.12244.

PMID:
24433178
15.

A paucity of liver disease in Canadian Inuit with chronic hepatitis B virus, subgenotype B6 infection.

Minuk GY, Macrury S, Uhanova J, Caouette S, Coleman N, Cummings K, Larke B, Vardy L, Triet Huyn C, Osiowy C.

J Viral Hepat. 2013 Dec;20(12):890-6. doi: 10.1111/jvh.12121. Epub 2013 May 29.

PMID:
24304459
16.

p27 is regulated independently of Skp2 in the absence of Cdk2.

Kotoshiba S, Gopinathan L, Pfeiffenberger E, Rahim A, Vardy LA, Nakayama K, Nakayama KI, Kaldis P.

Biochim Biophys Acta. 2014 Feb;1843(2):436-45. doi: 10.1016/j.bbamcr.2013.11.005. Epub 2013 Nov 21.

17.

Understanding translational control mechanisms of the mTOR pathway in CHO cells by polysome profiling.

Courtes FC, Vardy L, Wong NS, Bardor M, Yap MG, Lee DY.

N Biotechnol. 2014 Sep 25;31(5):514-23. doi: 10.1016/j.nbt.2013.10.003. Epub 2013 Oct 22.

PMID:
24157712
18.

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.

Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E.

Genes Dev. 2013 Sep 1;27(17):1903-16. doi: 10.1101/gad.219899.113.

19.

Translatome analysis of CHO cells to identify key growth genes.

Courtes FC, Lin J, Lim HL, Ng SW, Wong NS, Koh G, Vardy L, Yap MG, Loo B, Lee DY.

J Biotechnol. 2013 Sep 10;167(3):215-24. doi: 10.1016/j.jbiotec.2013.07.010. Epub 2013 Jul 19.

PMID:
23876478
20.

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence.

Dreesen O, Chojnowski A, Ong PF, Zhao TY, Common JE, Lunny D, Lane EB, Lee SJ, Vardy LA, Stewart CL, Colman A.

J Cell Biol. 2013 Mar 4;200(5):605-17. doi: 10.1083/jcb.201206121. Epub 2013 Feb 25.

21.

A role for polyamine regulators in ESC self-renewal.

Zhao T, Goh KJ, Ng HH, Vardy LA.

Cell Cycle. 2012 Dec 15;11(24):4517-23. doi: 10.4161/cc.22772. Epub 2012 Nov 19. Review.

22.

miR-Sens--a retroviral dual-luciferase reporter to detect microRNA activity in primary cells.

Beillard E, Ong SC, Giannakakis A, Guccione E, Vardy LA, Voorhoeve PM.

RNA. 2012 May;18(5):1091-100. doi: 10.1261/rna.031831.111. Epub 2012 Mar 14.

23.

AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells.

Zhang D, Zhao T, Ang HS, Chong P, Saiki R, Igarashi K, Yang H, Vardy LA.

Genes Dev. 2012 Mar 1;26(5):461-73. doi: 10.1101/gad.182998.111.

24.

Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors.

Brown S, Teo A, Pauklin S, Hannan N, Cho CH, Lim B, Vardy L, Dunn NR, Trotter M, Pedersen R, Vallier L.

Stem Cells. 2011 Aug;29(8):1176-85. doi: 10.1002/stem.666.

25.

Transcriptional consequences of genomic structural aberrations in breast cancer.

Inaki K, Hillmer AM, Ukil L, Yao F, Woo XY, Vardy LA, Zawack KF, Lee CW, Ariyaratne PN, Chan YS, Desai KV, Bergh J, Hall P, Putti TC, Ong WL, Shahab A, Cacheux-Rataboul V, Karuturi RK, Sung WK, Ruan X, Bourque G, Ruan Y, Liu ET.

Genome Res. 2011 May;21(5):676-87. doi: 10.1101/gr.113225.110. Epub 2011 Apr 5.

26.

Dietary sodium intake among Canadian adults with and without hypertension.

Shi Y, de Groh M, Morrison H, Robinson C, Vardy L.

Chronic Dis Can. 2011 Mar;31(2):79-87.

27.

PCBP1 suppresses the translation of metastasis-associated PRL-3 phosphatase.

Wang H, Vardy LA, Tan CP, Loo JM, Guo K, Li J, Lim SG, Zhou J, Chng WJ, Ng SB, Li HX, Zeng Q.

Cancer Cell. 2010 Jul 13;18(1):52-62. doi: 10.1016/j.ccr.2010.04.028.

28.

Cancer prevention and population-based screening.

Luciani S, Vardy L, Paci E, Adewole I, Sasco A, Calvacante T; ICCC-3 Session C Group.

Tumori. 2009 Sep-Oct;95(5):597-609.

PMID:
19999950
29.

Regulation of Cyclin A protein in meiosis and early embryogenesis.

Vardy L, Pesin JA, Orr-Weaver TL.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1838-43. doi: 10.1073/pnas.0813237106. Epub 2009 Jan 30.

30.

Regulating translation of maternal messages: multiple repression mechanisms.

Vardy L, Orr-Weaver TL.

Trends Cell Biol. 2007 Nov;17(11):547-54. Epub 2007 Oct 29.

PMID:
18029182
31.

The Drosophila PNG kinase complex regulates the translation of cyclin B.

Vardy L, Orr-Weaver TL.

Dev Cell. 2007 Jan;12(1):157-66.

32.

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.

Tadros W, Goldman AL, Babak T, Menzies F, Vardy L, Orr-Weaver T, Hughes TR, Westwood JT, Smibert CA, Lipshitz HD.

Dev Cell. 2007 Jan;12(1):143-55.

33.
34.

Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator.

Lee LA, Lee E, Anderson MA, Vardy L, Tahinci E, Ali SM, Kashevsky H, Benasutti M, Kirschner MW, Orr-Weaver TL.

Dev Cell. 2005 Mar;8(3):435-42.

35.

Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.

Sato M, Vardy L, Angel Garcia M, Koonrugsa N, Toda T.

Mol Biol Cell. 2004 Apr;15(4):1609-22. Epub 2004 Jan 23.

36.

Viral hepatitis in a Canadian First Nations community.

Minuk GY, Zhang M, Wong SG, Uhanova J, Bernstein CN, Martin B, Dawood MR, Vardy L, Giulvi A.

Can J Gastroenterol. 2003 Oct;17(10):593-6.

PMID:
14571297
37.

Deletion of Mia1/Alp7 activates Mad2-dependent spindle assembly checkpoint in fission yeast.

Sato M, Koonrugsa N, Toda T, Vardy L, Tournier S, Millar JB.

Nat Cell Biol. 2003 Sep;5(9):764-6; author reply 766. No abstract available.

PMID:
12951601
40.

Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.

Ochotorena IL, Hirata D, Kominami K, Potashkin J, Sahin F, Wentz-Hunter K, Gould KL, Sato K, Yoshida Y, Vardy L, Toda T.

J Cell Sci. 2001 Aug;114(Pt 16):2911-20.

43.
44.

Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

Radcliffe PA, Hirata D, Vardy L, Toda T.

Mol Biol Cell. 1999 Sep;10(9):2987-3001.

46.

Effects on mood of a life-styles program for the rehabilitation of injured workers.

Hannah TE, Kozma A, Stones M, Mosher D, Vardy L.

J Occup Med. 1989 May;31(5):454-7.

PMID:
2715854
47.

Perceived benefits of a lifestyles modification program in the rehabilitation of Worker's Compensation recipients.

Hannah TE, Hannah E, Mosher D, Vardy L.

Can J Public Health. 1988 Sep-Oct;79(5):323-6. No abstract available.

PMID:
2972353

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