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Items: 17


Three New Cs for CRISPR: Collateral, Communicate, Cooperate.

Varble A, Marraffini LA.

Trends Genet. 2019 Jun;35(6):446-456. doi: 10.1016/j.tig.2019.03.009. Epub 2019 Apr 27. Review.


Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci.

Varble A, Meaden S, Barrangou R, Westra ER, Marraffini LA.

Nat Microbiol. 2019 Jun;4(6):956-963. doi: 10.1038/s41564-019-0400-2. Epub 2019 Mar 18.


Sociodemographic Factors Associated With Engagement in Diabetes Self-management Education Among People With Diabetes in the United States.

Adjei Boakye E, Varble A, Rojek R, Peavler O, Trainer AK, Osazuwa-Peters N, Hinyard L.

Public Health Rep. 2018 Nov;133(6):685-691. doi: 10.1177/0033354918794935. Epub 2018 Sep 17.


Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts.

Goldberg GW, McMillan EA, Varble A, Modell JW, Samai P, Jiang W, Marraffini LA.

Nat Commun. 2018 Jan 4;9(1):61. doi: 10.1038/s41467-017-02557-2.


Sustained reduction in rates of hospital-onset Clostridium difficile infection using an automated electronic health record protocol.

Khoury JA, Sistrunk WW, Hixson F, Duncan M, Perry A, Varble A, Bryant AM.

Am J Infect Control. 2018 May;46(5):542-548. doi: 10.1016/j.ajic.2017.09.029. Epub 2017 Nov 21.


Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape.

Pyenson NC, Gayvert K, Varble A, Elemento O, Marraffini LA.

Cell Host Microbe. 2017 Sep 13;22(3):343-353.e3. doi: 10.1016/j.chom.2017.07.016. Epub 2017 Aug 17.


The vesicular stomatitis virus matrix protein inhibits NF-κB activation in mouse L929 cells.

Varble AJ, Ried CD, Hammond WJ, Marquis KA, Woodruff MC, Ferran MC.

Virology. 2016 Dec;499:99-104. doi: 10.1016/j.virol.2016.09.009. Epub 2016 Sep 17.


In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus.

Benitez AA, Panis M, Xue J, Varble A, Shim JV, Frick AL, López CB, Sachs D, tenOever BR.

Cell Rep. 2015 Jun 23;11(11):1714-26. doi: 10.1016/j.celrep.2015.05.032. Epub 2015 Jun 11.


Influenza A virus transmission bottlenecks are defined by infection route and recipient host.

Varble A, Albrecht RA, Backes S, Crumiller M, Bouvier NM, Sachs D, García-Sastre A, tenOever BR.

Cell Host Microbe. 2014 Nov 12;16(5):691-700. doi: 10.1016/j.chom.2014.09.020. Epub 2014 Oct 23.


Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense.

Moy RH, Cole BS, Yasunaga A, Gold B, Shankarling G, Varble A, Molleston JM, tenOever BR, Lynch KW, Cherry S.

Cell. 2014 Aug 14;158(4):764-777. doi: 10.1016/j.cell.2014.06.023.


The Mammalian response to virus infection is independent of small RNA silencing.

Backes S, Langlois RA, Schmid S, Varble A, Shim JV, Sachs D, tenOever BR.

Cell Rep. 2014 Jul 10;8(1):114-25. doi: 10.1016/j.celrep.2014.05.038. Epub 2014 Jun 19.


An in vivo RNAi screening approach to identify host determinants of virus replication.

Varble A, Benitez AA, Schmid S, Sachs D, Shim JV, Rodriguez-Barrueco R, Panis M, Crumiller M, Silva JM, Sachidanandam R, tenOever BR.

Cell Host Microbe. 2013 Sep 11;14(3):346-56. doi: 10.1016/j.chom.2013.08.007.


Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses.

Langlois RA, Varble A, Chua MA, García-Sastre A, tenOever BR.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12117-22. doi: 10.1073/pnas.1206039109. Epub 2012 Jul 9.


Implications of RNA virus-produced miRNAs.

Varble A, ten Oever BR.

RNA Biol. 2011 Mar-Apr;8(2):190-4. Epub 2011 Mar 1.


Noncanonical cytoplasmic processing of viral microRNAs.

Shapiro JS, Varble A, Pham AM, Tenoever BR.

RNA. 2010 Nov;16(11):2068-74. doi: 10.1261/rna.2303610. Epub 2010 Sep 14.


Engineered RNA viral synthesis of microRNAs.

Varble A, Chua MA, Perez JT, Manicassamy B, García-Sastre A, tenOever BR.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11519-24. doi: 10.1073/pnas.1003115107. Epub 2010 Jun 7.


Influenza A virus-generated small RNAs regulate the switch from transcription to replication.

Perez JT, Varble A, Sachidanandam R, Zlatev I, Manoharan M, García-Sastre A, tenOever BR.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11525-30. doi: 10.1073/pnas.1001984107. Epub 2010 Jun 1.

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