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Items: 1 to 50 of 88

1.

Effectiveness of a community-based exercise training programme to increase physical activity level in patients with chronic obstructive pulmonary disease: A randomized controlled trial.

Varas AB, Córdoba S, Rodríguez-Andonaegui I, Rueda MR, García-Juez S, Vilaró J.

Physiother Res Int. 2018 Oct;23(4):e1740. doi: 10.1002/pri.1740. Epub 2018 Aug 31.

PMID:
30168228
2.

[Treatment of heparin-induced thrombocytopenia with rivaroxaban. Case report].

Rivera O G, Corsi S O, Pavlovic J A, Aizman S A, Varas A P.

Rev Med Chil. 2017 Sep;145(9):1213-1217. doi: 10.4067/s0034-98872017000901213. Spanish.

3.

Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells.

Martinez VG, Ontoria-Oviedo I, Ricardo CP, Harding SE, Sacedon R, Varas A, Zapata A, Sepulveda P, Vicente A.

Stem Cell Res Ther. 2017 Sep 29;8(1):208. doi: 10.1186/s13287-017-0659-2.

4.

BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in Bladder Cancer.

Martínez VG, Rubio C, Martínez-Fernández M, Segovia C, López-Calderón F, Garín MI, Teijeira A, Munera-Maravilla E, Varas A, Sacedón R, Guerrero F, Villacampa F, de la Rosa F, Castellano D, López-Collazo E, Paramio JM, Vicente Á, Dueñas M.

Clin Cancer Res. 2017 Dec 1;23(23):7388-7399. doi: 10.1158/1078-0432.CCR-17-1004. Epub 2017 Sep 19.

PMID:
28928159
5.

Characterization of human fibroblastic reticular cells as potential immunotherapeutic tools.

Valencia J, Jiménez E, Martínez VG, Del Amo BG, Hidalgo L, Entrena A, Fernández-Sevilla LM, Del Río F, Varas A, Vicente Á, Sacedón R.

Cytotherapy. 2017 May;19(5):640-653. doi: 10.1016/j.jcyt.2017.01.010. Epub 2017 Mar 2.

PMID:
28262465
6.

Au13-nAgn clusters: a remarkably simple trend.

Munoz F, Varas A, Rogan J, Valdivia JA, Kiwi M.

Phys Chem Chem Phys. 2015 Nov 11;17(45):30492-8. doi: 10.1039/c5cp05664k.

PMID:
26513198
7.

Anisotropy Effects on the Plasmonic Response of Nanoparticle Dimers.

Varas A, García-González P, García-Vidal FJ, Rubio A.

J Phys Chem Lett. 2015 May 21;6(10):1891-8. doi: 10.1021/acs.jpclett.5b00573. Epub 2015 May 6.

PMID:
26263265
8.

Blockade of bone morphogenetic protein signaling potentiates the pro-inflammatory phenotype induced by interleukin-17 and tumor necrosis factor-α combination in rheumatoid synoviocytes.

Varas A, Valencia J, Lavocat F, Martínez VG, Thiam NN, Hidalgo L, Fernández-Sevilla LM, Sacedón R, Vicente A, Miossec P.

Arthritis Res Ther. 2015 Jul 28;17:192. doi: 10.1186/s13075-015-0710-6.

9.

The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis.

Martínez VG, Sacedón R, Hidalgo L, Valencia J, Fernández-Sevilla LM, Hernández-López C, Vicente A, Varas A.

PLoS One. 2015 Jun 25;10(6):e0131453. doi: 10.1371/journal.pone.0131453. eCollection 2015.

10.

Mesenchymal stem cells derived from low risk acute lymphoblastic leukemia patients promote NK cell antitumor activity.

Entrena A, Varas A, Vázquez M, Melen GJ, Fernández-Sevilla LM, García-Castro J, Ramírez M, Zapata AG, Vicente Á.

Cancer Lett. 2015 Jul 28;363(2):156-65. doi: 10.1016/j.canlet.2015.04.012. Epub 2015 Apr 23.

PMID:
25917077
11.

A discrete population of IFN λ-expressing BDCA3hi dendritic cells is present in human thymus.

Martínez VG, Canseco NM, Hidalgo L, Valencia J, Entrena A, Fernández-Sevilla LM, Hernández-López C, Sacedón R, Vicente A, Varas A.

Immunol Cell Biol. 2015 Aug;93(7):673-8. doi: 10.1038/icb.2015.22. Epub 2015 Mar 10.

PMID:
25753268
12.

Real-space grids and the Octopus code as tools for the development of new simulation approaches for electronic systems.

Andrade X, Strubbe D, De Giovannini U, Larsen AH, Oliveira MJ, Alberdi-Rodriguez J, Varas A, Theophilou I, Helbig N, Verstraete MJ, Stella L, Nogueira F, Aspuru-Guzik A, Castro A, Marques MA, Rubio A.

Phys Chem Chem Phys. 2015 Dec 21;17(47):31371-96. doi: 10.1039/c5cp00351b.

PMID:
25721500
13.

Wnt5a signaling increases IL-12 secretion by human dendritic cells and enhances IFN-γ production by CD4+ T cells.

Valencia J, Martínez VG, Hidalgo L, Hernández-López C, Canseco NM, Vicente A, Varas A, Sacedón R.

Immunol Lett. 2014 Nov;162(1 Pt A):188-99. doi: 10.1016/j.imlet.2014.08.015. Epub 2014 Sep 6.

PMID:
25196330
14.

Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling.

Robson NC, Hidalgo L, Mc Alpine T, Wei H, Martínez VG, Entrena A, Melen GJ, MacDonald AS, Phythian-Adams A, Sacedón R, Maraskovsky E, Cebon J, Ramírez M, Vicente A, Varas A.

Cancer Res. 2014 Sep 15;74(18):5019-5031. doi: 10.1158/0008-5472.CAN-13-2845. Epub 2014 Jul 18.

15.

Autocrine activation of canonical BMP signaling regulates PD-L1 and PD-L2 expression in human dendritic cells.

Martínez VG, Hidalgo L, Valencia J, Hernández-López C, Entrena A, del Amo BG, Zapata AG, Vicente A, Sacedón R, Varas A.

Eur J Immunol. 2014 Apr;44(4):1031-8. doi: 10.1002/eji.201343693. Epub 2014 Feb 16.

16.

A strategy to find minimal energy nanocluster structures.

Rogan J, Varas A, Valdivia JA, Kiwi M.

J Comput Chem. 2013 Nov 5;34(29):2548-56. doi: 10.1002/jcc.23419. Epub 2013 Aug 26.

PMID:
24037778
17.

Copper(I)-catalyzed azide-alkyne cycloadditions in microflow: catalyst activity, high-T operation, and an integrated continuous copper scavenging unit.

Varas AC, Noël T, Wang Q, Hessel V.

ChemSusChem. 2012 Sep;5(9):1703-7. doi: 10.1002/cssc.201200323. Epub 2012 Jun 29.

PMID:
22753337
18.

[Subdural empyema secondary to sinusitis. A pediatric case report].

Varas AH, García IS, Galarraga LM, Aguirre MH, Romero JC, Iturbe EB.

An Sist Sanit Navar. 2011 Sep-Dec;34(3):519-22. Spanish.

19.

Expression of BMPRIA on human thymic NK cell precursors: role of BMP signaling in intrathymic NK cell development.

Hidalgo L, Martínez VG, Valencia J, Hernández-López C, Vázquez MN, Nuñez JR, Zapata AG, Sacedón R, Varas A, Vicente A.

Blood. 2012 Feb 23;119(8):1861-71. doi: 10.1182/blood-2011-07-370650. Epub 2011 Dec 30.

20.

Wnt5a skews dendritic cell differentiation to an unconventional phenotype with tolerogenic features.

Valencia J, Hernández-López C, Martínez VG, Hidalgo L, Zapata AG, Vicente Á, Varas A, Sacedón R.

J Immunol. 2011 Oct 15;187(8):4129-39. doi: 10.4049/jimmunol.1101243. Epub 2011 Sep 14.

21.

The canonical BMP signaling pathway is involved in human monocyte-derived dendritic cell maturation.

Martínez VG, Hernández-López C, Valencia J, Hidalgo L, Entrena A, Zapata AG, Vicente A, Sacedón R, Varas A.

Immunol Cell Biol. 2011 Jul;89(5):610-8. doi: 10.1038/icb.2010.135. Epub 2010 Nov 23.

PMID:
21102536
22.

Dissecting the functions of Gli transcription factors in T-cell development.

Varas A, Sacedón R.

Cell Cycle. 2010 Nov 15;9(22):4428-9. Epub 2010 Nov 15. No abstract available.

PMID:
21088481
23.

Resonance, criticality, and emergence in city traffic investigated in cellular automaton models.

Varas A, Cornejo MD, Toledo BA, Muñoz V, Rogan J, Zarama R, Valdivia JA.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Nov;80(5 Pt 2):056108. Epub 2009 Nov 19.

PMID:
20365044
24.

The CXCL12/CXCR4 pair in aged human thymus.

Hernández-López C, Varas A, Sacedón R, Martínez VG, Hidalgo L, Valencia J, Zapata AG, Vicente A.

Neuroimmunomodulation. 2010;17(3):217-20. doi: 10.1159/000258728. Epub 2010 Feb 4.

PMID:
20134207
25.

Transient beta-catenin stabilization modifies lineage output from human thymic CD34+CD1a- progenitors.

Valencia J, Hernández-López C, Martínez VG, Hidalgo L, Zapata AG, Vicente A, Varas A, Sacedón R.

J Leukoc Biol. 2010 Mar;87(3):405-14. doi: 10.1189/jlb.0509344. Epub 2009 Dec 1.

PMID:
19952356
26.

Interplay between BMP4 and IL-7 in human intrathymic precursor cells.

Varas A, Sacedón R, Hidalgo L, Martínez VG, Valencia J, Cejalvo T, Zapata A, Hernández-López C, Vicente A.

Cell Cycle. 2009 Dec 15;8(24):4119-26. Epub 2009 Dec 21.

PMID:
19923894
27.

CXCL12/CXCR4 signaling promotes human thymic dendritic cell survival regulating the Bcl-2/Bax ratio.

Hernández-López C, Valencia J, Hidalgo L, Martínez VG, Zapata AG, Sacedón R, Varas A, Vicente A.

Immunol Lett. 2008 Oct 30;120(1-2):72-8. doi: 10.1016/j.imlet.2008.07.006. Epub 2008 Aug 8.

PMID:
18692524
28.

Survival and function of human thymic dendritic cells are dependent on autocrine Hedgehog signaling.

Varas A, Hernández-López C, Valencia J, Mattavelli S, Martínez VG, Hidalgo L, Gutiérrez-Frías C, Zapata AG, Sacedón R, Vicente A.

J Leukoc Biol. 2008 Jun;83(6):1476-83. doi: 10.1189/jlb.1107792. Epub 2008 Mar 11.

PMID:
18334540
29.

Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development.

Cejalvo T, Sacedón R, Hernández-López C, Diez B, Gutierrez-Frías C, Valencia J, Zapata AG, Varas A, Vicente A.

Immunology. 2007 May;121(1):94-104.

30.

Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis.

Sacedón R, Díez B, Nuñez V, Hernández-López C, Gutierrez-Frías C, Cejalvo T, Outram SV, Crompton T, Zapata AG, Vicente A, Varas A.

J Immunol. 2005 Feb 1;174(3):1456-61.

31.

[Nonpenetrating deep trabeculectomy treated with mitomycin C, without implant. A prospective evaluation of 55 cases].

González Bouchon J, González Mathiesen I, González Galvez M, Marin R, Varas A, Montesinos TM.

J Fr Ophtalmol. 2004 Oct;27(8):907-11. French.

32.

Sonic hedgehog regulates early human thymocyte differentiation by counteracting the IL-7-induced development of CD34+ precursor cells.

Gutiérrez-Frías C, Sacedón R, Hernández-López C, Cejalvo T, Crompton T, Zapata AG, Varas A, Vicente A.

J Immunol. 2004 Oct 15;173(8):5046-53.

33.

Reduced thymocyte development in sonic hedgehog knockout embryos.

Shah DK, Hager-Theodorides AL, Outram SV, Ross SE, Varas A, Crompton T.

J Immunol. 2004 Feb 15;172(4):2296-306.

34.

Age-dependent changes in thymic macrophages and dendritic cells.

Varas A, Sacedón R, Hernandez-López C, Jiménez E, García-Ceca J, Arias-Díaz J, Zapata AG, Vicente A.

Microsc Res Tech. 2003 Dec 15;62(6):501-7. Review.

PMID:
14635143
35.

Expression of hedgehog proteins in the human thymus.

Sacedón R, Varas A, Hernández-López C, Gutiérrez-deFrías C, Crompton T, Zapata AG, Vicente A.

J Histochem Cytochem. 2003 Nov;51(11):1557-66.

36.

The role of morphogens in T-cell development.

Varas A, Hager-Theodorides AL, Sacedón R, Vicente A, Zapata AG, Crompton T.

Trends Immunol. 2003 Apr;24(4):197-206. Review.

PMID:
12697452
37.

Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation.

Hager-Theodorides AL, Outram SV, Shah DK, Sacedon R, Shrimpton RE, Vicente A, Varas A, Crompton T.

J Immunol. 2002 Nov 15;169(10):5496-504.

38.

Expression and function of the Eph A receptors and their ligands ephrins A in the rat thymus.

Muñoz JJ, Alonso-C LM, Sacedón R, Crompton T, Vicente A, Jiménez E, Varas A, Zapata AG.

J Immunol. 2002 Jul 1;169(1):177-84.

39.
40.

Diacylglycerol kinase alpha activity promotes survival of CD4+ 8+ double positive cells during thymocyte development.

Outram SV, Crompton T, Merida I, Varas A, Martinez-A C.

Immunology. 2002 Apr;105(4):391-8.

41.

Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development.

Hernández-López C, Varas A, Sacedón R, Jiménez E, Muñoz JJ, Zapata AG, Vicente A.

Blood. 2002 Jan 15;99(2):546-54.

42.

Distinct mechanisms contribute to generate and change the CD4:CD8 cell ratio during thymus development: a role for the Notch ligand, Jagged1.

Jiménez E, Vicente A, Sacedón R, Muñoz JJ, Weinmaster G, Zapata AG, Varas A.

J Immunol. 2001 May 15;166(10):5898-908.

43.

Role of glucocorticoids in early T-cell differentiation.

Sacedón R, Vicente A, Varas A, Jiménez E, Muñoz JJ, Zapata AG.

Ann N Y Acad Sci. 2000;917:732-40.

PMID:
11268401
44.

Erratum.

Outram SV, Varas A, Pepicelli CV, Crompton T.

Immunity. 2000 Oct 1;13(4):585. No abstract available.

45.

Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte.

Outram SV, Varas A, Pepicelli CV, Crompton T.

Immunity. 2000 Aug;13(2):187-97. Erratum in: Immunity 2000 Oct;13(4):585.

46.

Effect of melatonin treatment on 24-h variations in responses to mitogens and lymphocyte subset populations in rat submaxillary lymph nodes.

Castrillón PO, Esquifino AI, Varas A, Zapata A, Cutrera RA, Cardinali DP.

J Neuroendocrinol. 2000 Aug;12(8):758-65.

PMID:
10929088
47.

Analysis of the human neonatal thymus: evidence for a transient thymic involution.

Varas A, Jiménez E, Sacedón R, Rodríguez-Mahou M, Maroto E, Zapata AG, Vicente A.

J Immunol. 2000 Jun 15;164(12):6260-7.

48.

Early maturation of T-cell progenitors in the absence of glucocorticoids.

Sacedón R, Vicente A, Varas A, Jiménez E, Muñoz JJ, Zapata AG.

Blood. 1999 Oct 15;94(8):2819-26.

49.

Partial blockade of T-cell differentiation during ontogeny and marked alterations of the thymic microenvironment in transgenic mice with impaired glucocorticoid receptor function.

Sacedón R, Vicente A, Varas A, Morale MC, Barden N, Marchetti B, Zapata AG.

J Neuroimmunol. 1999 Aug 3;98(2):157-67.

PMID:
10430049
50.

Glucocorticoid-mediated regulation of thymic dendritic cell function.

Sacedón R, Vicente A, Varas A, Jiménez E, Muñoz JJ, Zapata AG.

Int Immunol. 1999 Aug;11(8):1217-24.

PMID:
10421779

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