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Items: 9

1.

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma.

Pérez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, Sebastian ES, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, González-Barca E, Muncunill J, Navarro JT, Piris MA, Cossio FP, Esteller M.

Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7. No abstract available.

2.

Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study.

Otaegui D, Masdeu C, Aldaba E, Vara Y, Zubia A, San Sebastian E, Alcalá M, Villafruela S, Cossío FP, Rodriguez-Gascón A.

Biomed Chromatogr. 2015 Aug;29(8):1249-58. doi: 10.1002/bmc.3414. Epub 2015 Jan 23.

PMID:
25616154
3.

Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development.

San Sebastián E, Zimmerman T, Zubia A, Vara Y, Martin E, Sirockin F, Dejaegere A, Stote RH, Lopez X, Pantoja-Uceda D, Valcárcel M, Mendoza L, Vidal-Vanaclocha F, Cossío FP, Blanco FJ.

J Med Chem. 2013 Feb 14;56(3):735-47. doi: 10.1021/jm3016848. Epub 2013 Jan 22.

PMID:
23339734
4.

Synthesis of 11C-labeled Kendine 91, a histone deacetylase inhibitor.

Aginagalde M, Gómez-Vallejo V, Vara Y, Cossío FP, Llop J.

Appl Radiat Isot. 2012 Oct;70(10):2552-7. doi: 10.1016/j.apradiso.2012.05.016. Epub 2012 Jun 7.

PMID:
22871301
5.

Regioselective preparation of benzo[b]furans from phenols and α-bromoketones.

Arias L, Vara Y, Cossío FP.

J Org Chem. 2012 Jan 6;77(1):266-75. doi: 10.1021/jo201841y. Epub 2011 Dec 12.

PMID:
22122090
6.

Formation of γ-oxoacids and 1H-pyrrol-2(5H)-ones from α,β-unsaturated ketones and ethyl nitroacetate.

Aginagalde M, Bello T, Masdeu C, Vara Y, Arrieta A, Cossío FP.

J Org Chem. 2010 Nov 5;75(21):7435-8. doi: 10.1021/jo101388x.

PMID:
20886821
7.

Tandem [8 + 2] cycloaddition--[2 + 6 + 2] dehydrogenation reactions involving imidazo[1,2-a]pyridines and imidazo[1,2-a]pyrimidines.

Aginagalde M, Vara Y, Arrieta A, Zangi R, Cebolla VL, Delgado-Camón A, Cossío FP.

J Org Chem. 2010 May 7;75(9):2776-84. doi: 10.1021/jo9022815.

PMID:
19921806
8.

Trans-stereoselectivity in the reaction between homophthalic anhydride and imines.

Vara Y, Bello T, Aldaba E, Arrieta A, Pizarro JL, Arriortua MI, Lopez X, Cossío FP.

Org Lett. 2008 Nov 6;10(21):4759-62. doi: 10.1021/ol801757r. Epub 2008 Sep 25.

PMID:
18816130
9.

Regiochemistry of the microwave-assisted reaction between aromatic amines and alpha-bromoketones to yield substituted 1H-indoles.

Vara Y, Aldaba E, Arrieta A, Pizarro JL, Arriortua MI, Cossío FP.

Org Biomol Chem. 2008 May 21;6(10):1763-72. doi: 10.1039/b719641e. Epub 2008 Mar 25.

PMID:
18452011

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