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Items: 37

1.

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics.

Ruso-Julve F, Pombero A, Pilar-Cuéllar F, García-Díaz N, Garcia-Lopez R, Juncal-Ruiz M, Castro E, Díaz Á, Vazquez-Bourgón J, García-Blanco A, Garro-Martinez E, Pisonero H, Estirado A, Ayesa-Arriola R, López-Giménez J, Mayor F Jr, Valdizán E, Meana J, Gonzalez-Maeso J, Martínez S, Vaqué JP, Crespo-Facorro B.

Transl Psychiatry. 2019 Nov 18;9(1):306. doi: 10.1038/s41398-019-0647-7.

2.

High prevalence of non-alcoholic fatty liver disease among hidradenitis suppurativa patients independent of classic metabolic risk factors.

Durán-Vian C, Arias-Loste MT, Hernández JL, Fernández V, González M, Iruzubieta P, Rasines L, González-Vela C, Vaqué JP, Blanco R, Crespo J, González-López MA.

J Eur Acad Dermatol Venereol. 2019 Nov;33(11):2131-2136. doi: 10.1111/jdv.15764. Epub 2019 Jul 22.

PMID:
31260574
3.

Advanced-stage mycosis fungoides: role of the signal transducer and activator of transcription 3, nuclear factor-κB and nuclear factor of activated T cells pathways.

Pérez C, Mondéjar R, García-Díaz N, Cereceda L, León A, Montes S, Durán Vian C, Pérez Paredes MG, González-Morán A, Alegre de Miguel V, Sanz Anquela JM, Frias J, Limeres MA, González LM, Martín Dávila F, Beltrán M, Mollejo M, Méndez JR, González MA, González García J, López R, Gómez A, Izquierdo F, Ramos R, Camacho C, Rodriguez-Pinilla SM, Martínez N, Vaqué JP, Ortiz-Romero PL, Piris MA.

Br J Dermatol. 2020 Jan;182(1):147-155. doi: 10.1111/bjd.18098. Epub 2019 Jul 25.

PMID:
31049933
4.

Applied diagnostics in liver cancer. Efficient combinations of sorafenib with targeted inhibitors blocking AKT/mTOR.

Llerena S, García-Díaz N, Curiel-Olmo S, Agraz-Doblas A, García-Blanco A, Pisonero H, Varela M, Santibáñez M, Almaraz C, Cereceda L, Martínez N, Arias-Loste MT, Puente Á, Martín-Ramos L, de Lope CR, Castillo-Suescun F, Cagigas-Fernandez C, Isidro P, Lopez-López C, Lopez-Hoyos M, Llorca J, Agüero J, Crespo-Facorro B, Varela I, Piris MÁ, Crespo J, Vaqué JP.

Oncotarget. 2018 Jul 20;9(56):30869-30882. doi: 10.18632/oncotarget.25766. eCollection 2018 Jul 20.

5.

Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell lines.

Mondejar R, Pérez C, Onaindia A, Martinez N, González-Rincón J, Pisonero H, Vaqué JP, Cereceda L, Santibañez M, Sánchez-Beato M, Piris MA.

PLoS One. 2017 May 15;12(5):e0177524. doi: 10.1371/journal.pone.0177524. eCollection 2017.

6.

Splenic diffuse red pulp small B-cell lymphoma displays increased expression of cyclin D3 and recurrent CCND3 mutations.

Curiel-Olmo S, Mondéjar R, Almaraz C, Mollejo M, Cereceda L, Marès R, Derdak S, Campos-Martín Y, Batlle A, González de Villambrosía S, Gut M, Blanc J, Traverse-Glehen A, Verney A, Baseggio L, Camacho FI, Wotherspoon A, Stamatopoulos K, Xochelli A, Papadaki T, Kanellis G, Ponzoni M, García-Cosío M, Vaqué JP, Beltrán S, Gut I, Piris MA, Martínez N.

Blood. 2017 Feb 23;129(8):1042-1045. doi: 10.1182/blood-2016-11-751024. Epub 2017 Jan 9. No abstract available.

PMID:
28069605
7.

Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.

González-Vela MDC, Curiel-Olmo S, Derdak S, Beltran S, Santibañez M, Martínez N, Castillo-Trujillo A, Gut M, Sánchez-Pacheco R, Almaraz C, Cereceda L, Llombart B, Agraz-Doblas A, Revert-Arce J, López Guerrero JA, Mollejo M, Marrón PI, Ortiz-Romero P, Fernandez-Cuesta L, Varela I, Gut I, Cerroni L, Piris MÁ, Vaqué JP.

J Invest Dermatol. 2017 Jan;137(1):197-206. doi: 10.1016/j.jid.2016.08.015. Epub 2016 Sep 1.

8.

Erratum: Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures.

Curiel-Olmo S, García-Castaño A, Vidal R, Pisonero H, Varela I, León-Castillo A, Trillo E, González-Vela C, García-Diaz N, Almaraz C, Moreno T, Cereceda L, Madureira R, Martinez N, Ortiz-Romero P, Valdizán E, Piris MA, Vaqué JP.

Oncotarget. 2016 Feb 2;7(5):6352. doi: 10.18632/oncotarget.7118. No abstract available.

9.

Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures.

Curiel-Olmo S, García-Castaño A, Vidal R, Pisonero H, Varela I, León-Castillo A, Trillo E, González-Vela C, García-Diaz N, Almaraz C, Moreno T, Cereceda L, Madureira R, Martinez N, Ortiz-Romero P, Valdizán E, Piris MA, Vaqué JP.

Oncotarget. 2015 Sep 22;6(28):25452-65. doi: 10.18632/oncotarget.4545. Erratum in: Oncotarget. 2016 Feb 2;7(5):6352. Piris, M and Vaqué, J [Corrected to Piris, MA and Vaqué, JP].

10.

Mutated JAK kinases and deregulated STAT activity are potential therapeutic targets in cutaneous T-cell lymphoma.

Pérez C, González-Rincón J, Onaindia A, Almaráz C, García-Díaz N, Pisonero H, Curiel-Olmo S, Gómez S, Cereceda L, Madureira R, Hospital M, Suárez-Massa D, Rodriguez-Peralto JL, Postigo C, Leon-Castillo A, González-Vela C, Martinez N, Ortiz-Romero P, Sánchez-Beato M, Piris MÁ, Vaqué JP.

Haematologica. 2015 Nov;100(11):e450-3. doi: 10.3324/haematol.2015.132837. Epub 2015 Aug 20. No abstract available.

11.

Correction: Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimens.

Vaqué JP, Martínez N, Varela I, Fernández F, Mayorga M, Derdak S, Beltrán S, Moreno T, Almaraz C, De Las Heras G, Bayés M, Gut I, Crespo J, Piris MA.

PLoS One. 2015 Apr 10;10(4):e0125459. doi: 10.1371/journal.pone.0125459. eCollection 2015. No abstract available.

12.

Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimens.

Vaqué JP, Martínez N, Varela I, Fernández F, Mayorga M, Derdak S, Beltrán S, Moreno T, Almaraz C, De Las Heras G, Bayés M, Gut I, Crespo J, Piris MA.

PLoS One. 2015 Mar 16;10(3):e0119946. doi: 10.1371/journal.pone.0119946. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0125459.

13.

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS.

Cancer Cell. 2014 Jun 16;25(6):831-45. doi: 10.1016/j.ccr.2014.04.016. Epub 2014 May 29.

14.

B-cell lymphoma mutations: improving diagnostics and enabling targeted therapies.

Vaqué JP, Martínez N, Batlle-López A, Pérez C, Montes-Moreno S, Sánchez-Beato M, Piris MA.

Haematologica. 2014 Feb;99(2):222-31. doi: 10.3324/haematol.2013.096248. Review.

15.

PLCG1 mutations in cutaneous T-cell lymphomas.

Vaqué JP, Gómez-López G, Monsálvez V, Varela I, Martínez N, Pérez C, Domínguez O, Graña O, Rodríguez-Peralto JL, Rodríguez-Pinilla SM, González-Vela C, Rubio-Camarillo M, Martín-Sánchez E, Pisano DG, Papadavid E, Papadaki T, Requena L, García-Marco JA, Méndez M, Provencio M, Hospital M, Suárez-Massa D, Postigo C, San Segundo D, López-Hoyos M, Ortiz-Romero PL, Piris MA, Sánchez-Beato M.

Blood. 2014 Mar 27;123(13):2034-43. doi: 10.1182/blood-2013-05-504308. Epub 2014 Feb 4.

PMID:
24497536
16.

Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation.

Martínez N, Almaraz C, Vaqué JP, Varela I, Derdak S, Beltran S, Mollejo M, Campos-Martin Y, Agueda L, Rinaldi A, Kwee I, Gut M, Blanc J, Oscier D, Strefford JC, Martinez-Lopez J, Salar A, Sole F, Rodriguez-Peralto JL, Diez-Tascón C, García JF, Fraga M, Sebastián E, Alvés J, Menárguez J, González-Carreró J, Casado LF, Bayes M, Bertoni F, Gut I, Piris MA.

Leukemia. 2014 Jun;28(6):1334-40. doi: 10.1038/leu.2013.365. Epub 2013 Dec 3.

PMID:
24296945
17.

A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.

Vaqué JP, Dorsam RT, Feng X, Iglesias-Bartolome R, Forsthoefel DJ, Chen Q, Debant A, Seeger MA, Ksander BR, Teramoto H, Gutkind JS.

Mol Cell. 2013 Jan 10;49(1):94-108. doi: 10.1016/j.molcel.2012.10.018. Epub 2012 Nov 21.

18.

[The role of estrogen receptor alpha in breast cancer cell proliferation mediated by progestins].

Giulianelli S, Vaqué JP, Wargon V, Soldati R, Vanzulli SI, Martins R, Zeitlin E, Helguero L, Lamb C, Molinolo AA, Gutkind JS, Lanari C.

Medicina (B Aires). 2012;72(4):315-20. Spanish.

19.

MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).

Gómez-Casares MT, García-Alegria E, López-Jorge CE, Ferrándiz N, Blanco R, Alvarez S, Vaqué JP, Bretones G, Caraballo JM, Sánchez-Bailón P, Delgado MD, Martín-Perez J, Cigudosa JC, León J.

Oncogene. 2013 Apr 25;32(17):2239-46. doi: 10.1038/onc.2012.246. Epub 2012 Jun 18.

PMID:
22710719
20.

Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters.

Giulianelli S, Vaqué JP, Soldati R, Wargon V, Vanzulli SI, Martins R, Zeitlin E, Molinolo AA, Helguero LA, Lamb CA, Gutkind JS, Lanari C.

Cancer Res. 2012 May 1;72(9):2416-27. doi: 10.1158/0008-5472.CAN-11-3290. Epub 2012 Mar 6.

21.

Interleukin-21 expression and its association with proinflammatory cytokines in untreated chronic periodontitis patients.

Dutzan N, Vernal R, Vaque JP, García-Sesnich J, Hernandez M, Abusleme L, Dezerega A, Gutkind JS, Gamonal J.

J Periodontol. 2012 Jul;83(7):948-54. doi: 10.1902/jop.2011.110482. Epub 2011 Dec 19.

PMID:
22181687
22.

Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer.

Cerliani JP, Guillardoy T, Giulianelli S, Vaque JP, Gutkind JS, Vanzulli SI, Martins R, Zeitlin E, Lamb CA, Lanari C.

Cancer Res. 2011 May 15;71(10):3720-31. doi: 10.1158/0008-5472.CAN-10-3074. Epub 2011 Apr 4. Erratum in: Cancer Res. 2011 Sep 1;71(17):5941.

23.

MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.

Albajar M, Gómez-Casares MT, Llorca J, Mauleon I, Vaqué JP, Acosta JC, Bermúdez A, Donato N, Delgado MD, León J.

Mol Cancer Res. 2011 May;9(5):564-76. doi: 10.1158/1541-7786.MCR-10-0356. Epub 2011 Apr 1.

24.

Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.

Maruyama T, Li J, Vaque JP, Konkel JE, Wang W, Zhang B, Zhang P, Zamarron BF, Yu D, Wu Y, Zhuang Y, Gutkind JS, Chen W.

Nat Immunol. 2011 Jan;12(1):86-95. doi: 10.1038/ni.1965. Epub 2010 Dec 5.

25.

Activation of Ras and Rho GTPases and MAP Kinases by G-protein-coupled receptors.

Chiariello M, Vaqué JP, Crespo P, Gutkind JS.

Methods Mol Biol. 2010;661:137-50. doi: 10.1007/978-1-60761-795-2_8.

PMID:
20811981
26.

Ultrasensitive electrochemical immunosensor for oral cancer biomarker IL-6 using carbon nanotube forest electrodes and multilabel amplification.

Malhotra R, Patel V, Vaqué JP, Gutkind JS, Rusling JF.

Anal Chem. 2010 Apr 15;82(8):3118-23. doi: 10.1021/ac902802b.

27.

p73 plays a role in erythroid differentiation through GATA1 induction.

Marqués-García F, Ferrandiz N, Fernández-Alonso R, González-Cano L, Herreros-Villanueva M, Rosa-Garrido M, Fernández-García B, Vaque JP, Marqués MM, Alonso ME, Segovia JC, León J, Marín MC.

J Biol Chem. 2009 Aug 7;284(32):21139-56. doi: 10.1074/jbc.M109.026849. Epub 2009 Jun 9.

28.

Bobel-24 and derivatives induce caspase-independent death in pancreatic cancer regardless of apoptotic resistance.

Parreño M, Casanova I, Céspedes MV, Vaqué JP, Pavón MA, Leon J, Mangues R.

Cancer Res. 2008 Aug 1;68(15):6313-23. doi: 10.1158/0008-5472.CAN-08-1054.

29.

c-Myc inhibits Ras-mediated differentiation of pheochromocytoma cells by blocking c-Jun up-regulation.

Vaqué JP, Fernández-García B, García-Sanz P, Ferrandiz N, Bretones G, Calvo F, Crespo P, Marín MC, León J.

Mol Cancer Res. 2008 Feb;6(2):325-39. doi: 10.1158/1541-7786.MCR-07-0180.

30.

Nuclear compartmentalization and dynamics of the poly(A)-binding protein nuclear 1 (PABPN1) inclusions in supraoptic neurons under physiological and osmotic stress conditions.

Villagra NT, Bengoechea R, Vaqué JP, Llorca J, Berciano MT, Lafarga M.

Mol Cell Neurosci. 2008 Mar;37(3):622-33. doi: 10.1016/j.mcn.2007.12.012. Epub 2007 Dec 15.

PMID:
18255312
31.

Characterization of a new SUMO-1 nuclear body (SNB) enriched in pCREB, CBP, c-Jun in neuron-like UR61 cells.

Navascués J, Bengoechea R, Tapia O, Vaqué JP, Lafarga M, Berciano MT.

Chromosoma. 2007 Oct;116(5):441-51. Epub 2007 May 26.

PMID:
17549507
32.

MAP kinases and the control of nuclear events.

Turjanski AG, Vaqué JP, Gutkind JS.

Oncogene. 2007 May 14;26(22):3240-53. Review.

PMID:
17496919
33.

Novel triiodophenol derivatives induce caspase-independent mitochondrial cell death in leukemia cells inhibited by Myc.

Parreño M, Vaqué JP, Casanova I, Frade P, Céspedes MV, Pavón MA, Molins A, Camacho M, Vila L, Nomdedeu JF, Mangues R, León J.

Mol Cancer Ther. 2006 May;5(5):1166-75.

34.

p73 cooperates with Ras in the activation of MAP kinase signaling cascade.

Fernandez-Garcia B, Vaqué JP, Herreros-Villanueva M, Marques-Garcia F, Castrillo F, Fernandez-Medarde A, León J, Marín MC.

Cell Death Differ. 2007 Feb;14(2):254-65. Epub 2006 Apr 28.

35.

Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.

Vaqué JP, Navascues J, Shiio Y, Laiho M, Ajenjo N, Mauleon I, Matallanas D, Crespo P, León J.

J Biol Chem. 2005 Jan 14;280(2):1112-22. Epub 2004 Nov 4.

36.

C-myc expression in cell lines derived from chronic myeloid leukemia.

Gómez-Casares MT, Vaqué JP, Lemes A, Molero T, Delgado MD, León J.

Haematologica. 2004 Feb;89(2):241-3. No abstract available.

37.

H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism.

Delgado MD, Vaqué JP, Arozarena I, López-Ilasaca MA, Martínez C, Crespo P, León J.

Oncogene. 2000 Feb 10;19(6):783-90.

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