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Items: 5

1.

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo.

Xu Y, Huang L, Kirschman JL, Vanover DA, Tiwari PM, Santangelo PJ, Shen X, Russell DG.

J Immunol. 2019 Jan 15;202(2):608-617. doi: 10.4049/jimmunol.1800924. Epub 2018 Dec 12.

PMID:
30541883
2.

High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.

Sago CD, Lokugamage MP, Paunovska K, Vanover DA, Monaco CM, Shah NN, Gamboa Castro M, Anderson SE, Rudoltz TG, Lando GN, Munnilal Tiwari P, Kirschman JL, Willett N, Jang YC, Santangelo PJ, Bryksin AV, Dahlman JE.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9944-E9952. doi: 10.1073/pnas.1811276115. Epub 2018 Oct 1. Erratum in: Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11427.

3.

In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity.

Loomis KH, Lindsay KE, Zurla C, Bhosle SM, Vanover DA, Blanchard EL, Kirschman JL, Bellamkonda RV, Santangelo PJ.

Bioconjug Chem. 2018 Sep 19;29(9):3072-3083. doi: 10.1021/acs.bioconjchem.8b00443. Epub 2018 Aug 13.

PMID:
30067354
4.

A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.

Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, Kalathoor S, Vanover DA, Santangelo PJ, Ahmed R, Bryksin AV, Dahlman JE.

Nano Lett. 2018 Mar 14;18(3):2148-2157. doi: 10.1021/acs.nanolett.8b00432. Epub 2018 Mar 5.

5.

Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction.

Bhosle SM, Loomis KH, Kirschman JL, Blanchard EL, Vanover DA, Zurla C, Habrant D, Edwards D, Baumhof P, Pitard B, Santangelo PJ.

Biomaterials. 2018 Mar;159:189-203. doi: 10.1016/j.biomaterials.2018.01.010. Epub 2018 Jan 6.

PMID:
29331806

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