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Items: 1 to 50 of 159

1.

Review article: biological mechanisms for symptom causation by individual FODMAP subgroups - the case for a more personalised approach to dietary restriction.

Wang XJ, Camilleri M, Vanner S, Tuck C.

Aliment Pharmacol Ther. 2019 Jul 15. doi: 10.1111/apt.15419. [Epub ahead of print] Review.

PMID:
31309595
2.

Patient Engagement and Multidisciplinary Involvement Has an Impact on Clinical Guideline Development and Decisions: A Comparison of Two Irritable Bowel Syndrome Guidelines Using the Same Data.

Moayyedi P, Marsiglio M, Andrews CN, Graff LA, Korownyk C, Kvern B, Lazarescu A, Liu L, MacQueen G, Paterson WG, Sidani S, Vanner SJ, Sinclair P, Marshall L, Fernandes A.

J Can Assoc Gastroenterol. 2019 Apr;2(1):30-36. doi: 10.1093/jcag/gwy072. Epub 2019 Jan 17.

PMID:
31294725
Free PMC Article
3.

Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS).

Moayyedi P, Andrews CN, MacQueen G, Korownyk C, Marsiglio M, Graff L, Kvern B, Lazarescu A, Liu L, Paterson WG, Sidani S, Vanner S.

J Can Assoc Gastroenterol. 2019 Apr;2(1):6-29. doi: 10.1093/jcag/gwy071. Epub 2019 Jan 17.

PMID:
31294724
Free PMC Article
4.

The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome.

Tuck CJ, Caminero A, Jiménez Vargas NN, Soltys CL, Jaramillo Polanco JO, Lopez Lopez CD, Constante M, Lourenssen SR, Verdu EF, Muir JG, Lomax AE, Reed DE, Vanner SJ.

Neurogastroenterol Motil. 2019 Jul 9:e13675. doi: 10.1111/nmo.13675. [Epub ahead of print]

PMID:
31290223
5.

Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2.

Zhao P, Pattison LA, Jensen DD, Jimenez-Vargas NN, Latorre R, Lieu T, Jaramillo JO, Lopez-Lopez C, Poole DP, Vanner SJ, Schmidt BL, Bunnett NW.

J Biol Chem. 2019 Jul 5;294(27):10649-10662. doi: 10.1074/jbc.RA118.006935. Epub 2019 May 29.

PMID:
31142616
6.

Exciting news from the editors of Neurogastroenterology and Motility.

Bredenoord AJ, Browning K, Galligan J, Corsetti M, Vanner S, Farmer AD.

Neurogastroenterol Motil. 2019 May 7:e13622. doi: 10.1111/nmo.13622. [Epub ahead of print] No abstract available.

PMID:
31062465
7.

Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission - confounded by the gut microbiome? Authors' reply.

Keshteli AH, Madsen KL, Mandal R, Boeckxstaens GE, Bercik P, De Palma G, Reed DE, Wishart D, Vanner S, Dieleman LA.

Aliment Pharmacol Ther. 2019 Apr;49(8):1088-1089. doi: 10.1111/apt.15200. No abstract available.

PMID:
30920043
8.

Activation of Peripheral Blood CD4+ T-Cells in IBS is not Associated with Gastrointestinal or Psychological Symptoms.

Nasser Y, Petes C, Simmers C, Basso L, Altier C, Gee K, Vanner SJ.

Sci Rep. 2019 Mar 6;9(1):3710. doi: 10.1038/s41598-019-40124-5.

9.

Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and potential biomarkers.

Keshteli AH, Madsen KL, Mandal R, Boeckxstaens GE, Bercik P, De Palma G, Reed DE, Wishart D, Vanner S, Dieleman LA.

Aliment Pharmacol Ther. 2019 Mar;49(6):723-732. doi: 10.1111/apt.15141. Epub 2019 Jan 31.

PMID:
30706502
10.

Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.

Balemans D, Aguilera-Lizarraga J, Florens MV, Jain P, Denadai-Souza A, Viola MF, Alpizar YA, Van Der Merwe S, Vanden Berghe P, Talavera K, Vanner S, Wouters MM, Boeckxstaens GE.

Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G338-G349. doi: 10.1152/ajpgi.00116.2018. Epub 2019 Jan 10.

PMID:
30629470
11.

Anti-Ro52 antibody acts on the S5-pore linker of hERG to chronically reduce channel expression.

Szendrey J, Lamothe SM, Vanner S, Guo J, Yang T, Li W, Davis J, Joneja M, Baranchuk A, Zhang S.

Cardiovasc Res. 2018 Dec 13. doi: 10.1093/cvr/cvy310. [Epub ahead of print]

PMID:
30544220
12.

Telomere length in the colon is related to colorectal adenoma prevalence.

Peacock SD, Massey TE, Vanner SJ, King WD.

PLoS One. 2018 Oct 17;13(10):e0205697. doi: 10.1371/journal.pone.0205697. eCollection 2018.

13.

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.

Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, Canals M, Veldhuis NA, Poole DP, McLean P, Hicks GA, Scheff N, Chen E, Bhattacharya A, Schmidt BL, Brierley SM, Vanner SJ, Bunnett NW.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7438-E7447. doi: 10.1073/pnas.1721891115. Epub 2018 Jul 16.

14.

Bulky DNA adduct levels in normal-appearing colon mucosa, and the prevalence of colorectal adenomas.

Ho V, Peacock S, Massey TE, Godschalk RW, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Biomarkers. 2018 Dec;23(8):735-741. doi: 10.1080/1354750X.2018.1485055. Epub 2018 Jul 23.

PMID:
29871536
15.

Co-expression of μ and δ opioid receptors by mouse colonic nociceptors.

Guerrero-Alba R, Valdez-Morales EE, Jiménez-Vargas NN, Bron R, Poole D, Reed D, Castro J, Campaniello M, Hughes PA, Brierley SM, Bunnett N, Lomax AE, Vanner S.

Br J Pharmacol. 2018 Jul;175(13):2622-2634. doi: 10.1111/bph.14222. Epub 2018 May 22.

16.

Breath Testing Consensus Guidelines for SIBO: RES IPSA LOCQUITOR.

Paterson W, Camilleri M, Simren M, Boeckxstaens G, Vanner SJ.

Am J Gastroenterol. 2017 Dec;112(12):1888-1889. doi: 10.1038/ajg.2017.233. No abstract available.

PMID:
29215610
17.

Dietary therapies for functional bowel symptoms: Recent advances, challenges, and future directions.

Tuck CJ, Vanner SJ.

Neurogastroenterol Motil. 2018 Jan;30(1). doi: 10.1111/nmo.13238. Epub 2017 Nov 2. Review.

PMID:
29094792
18.

Protease-Mediated Suppression of DRG Neuron Excitability by Commensal Bacteria.

Sessenwein JL, Baker CC, Pradhananga S, Maitland ME, Petrof EO, Allen-Vercoe E, Noordhof C, Reed DE, Vanner SJ, Lomax AE.

J Neurosci. 2017 Nov 29;37(48):11758-11768. doi: 10.1523/JNEUROSCI.1672-17.2017. Epub 2017 Oct 31.

19.

Exposure to meat-derived carcinogens and bulky DNA adduct levels in normal-appearing colon mucosa.

Ho V, Brunetti V, Peacock S, Massey TE, Godschalk RWL, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Mutat Res. 2017 Sep;821:5-12. doi: 10.1016/j.mrgentox.2017.06.005. Epub 2017 Jul 4.

PMID:
28735743
20.

News from the editors of Neurogastroenterology and Motility.

Galligan J, Bredenoord AJ, Vanner S, Browning K, Corsetti M, Farmer A.

Neurogastroenterol Motil. 2017 Aug;29(8). doi: 10.1111/nmo.13169. No abstract available.

PMID:
28699319
21.

A role for interleukin 17A in IBD-related neuroplasticity.

Cervi AL, Moynes DM, Chisholm SP, Nasser Y, Vanner SJ, Lomax AE.

Neurogastroenterol Motil. 2017 Nov;29(11). doi: 10.1111/nmo.13112. Epub 2017 May 30.

PMID:
28560787
22.

Sham acupuncture is as efficacious as true acupuncture for the treatment of IBS: A randomized placebo controlled trial.

Lowe C, Aiken A, Day AG, Depew W, Vanner SJ.

Neurogastroenterol Motil. 2017 Jul;29(7). doi: 10.1111/nmo.13040. Epub 2017 Mar 2.

PMID:
28251729
23.

Epithelial expression and function of trypsin-3 in irritable bowel syndrome.

Rolland-Fourcade C, Denadai-Souza A, Cirillo C, Lopez C, Jaramillo JO, Desormeaux C, Cenac N, Motta JP, Larauche M, Taché Y, Vanden Berghe P, Neunlist M, Coron E, Kirzin S, Portier G, Bonnet D, Alric L, Vanner S, Deraison C, Vergnolle N.

Gut. 2017 Oct;66(10):1767-1778. doi: 10.1136/gutjnl-2016-312094. Epub 2017 Jan 17.

24.

Emerging studies of human visceral nociceptors.

Reed DE, Vanner SJ.

Am J Physiol Gastrointest Liver Physiol. 2017 Mar 1;312(3):G201-G207. doi: 10.1152/ajpgi.00391.2016. Epub 2016 Dec 22. Review.

25.

Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis.

Guerrero-Alba R, Valdez-Morales EE, Jimenez-Vargas NN, Lopez-Lopez C, Jaramillo-Polanco J, Okamoto T, Nasser Y, Bunnett NW, Lomax AE, Vanner SJ.

Gut. 2017 Dec;66(12):2121-2131. doi: 10.1136/gutjnl-2016-311456. Epub 2016 Sep 2.

PMID:
27590998
26.

Rome IV Diagnostic Questionnaires and Tables for Investigators and Clinicians.

Palsson OS, Whitehead WE, van Tilburg MA, Chang L, Chey W, Crowell MD, Keefer L, Lembo AJ, Parkman HP, Rao SS, Sperber A, Spiegel B, Tack J, Vanner S, Walker LS, Whorwell P, Yang Y.

Gastroenterology. 2016 Feb 13. pii: S0016-5085(16)00180-3. doi: 10.1053/j.gastro.2016.02.014. [Epub ahead of print]

PMID:
27144634
27.

The Intestinal Microenvironment and Functional Gastrointestinal Disorders.

Barbara G, Feinle-Bisset C, Ghoshal UC, Quigley EM, Santos J, Vanner S, Vergnolle N, Zoetendal EG.

Gastroenterology. 2016 Feb 18. pii: S0016-5085(16)00219-5. doi: 10.1053/j.gastro.2016.02.028. [Epub ahead of print]

PMID:
27144620
28.

Fundamentals of Neurogastroenterology: Basic Science.

Vanner S, Greenwood-Van Meerveld B, Mawe G, Shea-Donohue T, Verdu EF, Wood J, Grundy D.

Gastroenterology. 2016 Feb 18. pii: S0016-5085(16)00184-0. doi: 10.1053/j.gastro.2016.02.018. [Epub ahead of print]

29.

Genetic and epigenetic variation in the DNMT3B and MTHFR genes and colorectal adenoma risk.

Ho V, Ashbury JE, Taylor S, Vanner S, King WD.

Environ Mol Mutagen. 2016 May;57(4):261-8. doi: 10.1002/em.22010. Epub 2016 Apr 8.

PMID:
27062459
30.

Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane.

Jensen DD, Zhao P, Jimenez-Vargas NN, Lieu T, Gerges M, Yeatman HR, Canals M, Vanner SJ, Poole DP, Bunnett NW.

J Biol Chem. 2016 May 20;291(21):11285-99. doi: 10.1074/jbc.M115.710681. Epub 2016 Mar 30.

32.

FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.

McIntosh K, Reed DE, Schneider T, Dang F, Keshteli AH, De Palma G, Madsen K, Bercik P, Vanner S.

Gut. 2017 Jul;66(7):1241-1251. doi: 10.1136/gutjnl-2015-311339. Epub 2016 Mar 14. Erratum in: Gut. 2019 Jul;68(7):1342.

PMID:
26976734
33.

Quantification of gene-specific methylation of DNMT3B and MTHFR using sequenom EpiTYPER®.

Ho V, Ashbury JE, Taylor S, Vanner S, King WD.

Data Brief. 2015 Nov 26;6:39-46. doi: 10.1016/j.dib.2015.11.039. eCollection 2016 Mar.

34.

Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome.

Wouters MM, Balemans D, Van Wanrooy S, Dooley J, Cibert-Goton V, Alpizar YA, Valdez-Morales EE, Nasser Y, Van Veldhoven PP, Vanbrabant W, Van der Merwe S, Mols R, Ghesquière B, Cirillo C, Kortekaas I, Carmeliet P, Peetermans WE, Vermeire S, Rutgeerts P, Augustijns P, Hellings PW, Belmans A, Vanner S, Bulmer DC, Talavera K, Vanden Berghe P, Liston A, Boeckxstaens GE.

Gastroenterology. 2016 Apr;150(4):875-87.e9. doi: 10.1053/j.gastro.2015.12.034. Epub 2016 Jan 2.

PMID:
26752109
35.

Stress increases descending inhibition in mouse and human colon.

Reed DE, Zhang Y, Beyak MJ, Lourenssen S, Blennerhassett MG, Paterson WG, Vanner SJ.

Neurogastroenterol Motil. 2016 Apr;28(4):569-80. doi: 10.1111/nmo.12755. Epub 2016 Jan 6.

PMID:
26744175
36.

Gene-specific DNA methylation of DNMT3B and MTHFR and colorectal adenoma risk.

Ho V, Ashbury JE, Taylor S, Vanner S, King WD.

Mutat Res. 2015 Dec;782:1-6. doi: 10.1016/j.mrfmmm.2015.09.005. Epub 2015 Oct 17.

PMID:
26485042
37.

Low-residue breakfast during the preparation for colonoscopy using a polyethylene glycol electrolyte solution: a randomised non-inferiority trial.

Flemming JA, Green J, Melicharkova A, Vanner S, Hookey L.

BMJ Open Gastroenterol. 2015 May 28;2(1):e000029. doi: 10.1136/bmjgast-2015-000029. eCollection 2015.

38.

Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA-Specified Leu-tRNA(UUA) Molecule.

Zhu XM, Hackl S, Thaker MN, Kalan L, Weber C, Urgast DS, Krupp EM, Brewer A, Vanner S, Szawiola A, Yim G, Feldmann J, Bechthold A, Wright GD, Zechel DL.

Chembiochem. 2015 Nov;16(17):2498-506. doi: 10.1002/cbic.201500402. Epub 2015 Oct 22.

PMID:
26374477
39.

Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe.

Barlow N, Nasser Y, Zhao P, Sharma N, Guerrero-Alba R, Edgington-Mitchell LE, Lieu T, Veldhuis NA, Poole DP, Conner JW, Lindström E, Craig AW, Graham B, Vanner SJ, Bunnett NW.

Neurogastroenterol Motil. 2015 Nov;27(11):1675-80. doi: 10.1111/nmo.12656. Epub 2015 Aug 24.

PMID:
26303377
40.

Mechanisms of Quality of Life and Social Support in Inflammatory Bowel Disease.

Katz L, Tripp DA, Ropeleski M, Depew W, Curtis Nickel J, Vanner S, Beyak MJ.

J Clin Psychol Med Settings. 2016 Mar;23(1):88-98. doi: 10.1007/s10880-015-9431-x.

PMID:
26280991
41.

Changing Biosynthetic Profiles by Expressing bldA in Streptomyces Strains.

Gessner A, Heitzler T, Zhang S, Klaus C, Murillo R, Zhao H, Vanner S, Zechel DL, Bechthold A.

Chembiochem. 2015 Oct 12;16(15):2244-52. doi: 10.1002/cbic.201500297. Epub 2015 Sep 23.

PMID:
26255983
42.

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain.

Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW.

J Biol Chem. 2015 May 29;290(22):13875-87. doi: 10.1074/jbc.M115.642736. Epub 2015 Apr 15.

43.

Concurrent psychological stress and infectious colitis is key to sustaining enhanced peripheral sensory signaling.

Spreadbury I, Ochoa-Cortes F, Ibeakanma C, Martin N, Hurlbut D, Vanner SJ.

Neurogastroenterol Motil. 2015 Mar;27(3):347-55. doi: 10.1111/nmo.12497. Epub 2014 Dec 17.

PMID:
25521605
44.

Meat-derived carcinogens, genetic susceptibility and colorectal adenoma risk.

Ho V, Peacock S, Massey TE, Ashbury JE, Vanner SJ, King WD.

Genes Nutr. 2014 Nov;9(6):430. doi: 10.1007/s12263-014-0430-6. Epub 2014 Sep 18.

45.

Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.

Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, McIntyre P, Vanner SJ, Korbmacher C, Bunnett NW.

J Biol Chem. 2014 Sep 26;289(39):27215-34. doi: 10.1074/jbc.M114.599712. Epub 2014 Aug 12. Erratum in: J Biol Chem. 2014 Dec 26;289(52):35858.

46.

A cross-sectional study of global DNA methylation and risk of colorectal adenoma.

King WD, Ashbury JE, Taylor SA, Tse MY, Pang SC, Louw JA, Vanner SJ.

BMC Cancer. 2014 Jul 7;14:488. doi: 10.1186/1471-2407-14-488.

47.

Biomarkers measured in buccal and blood leukocyte DNA as proxies for colon tissue global methylation.

Ashbury JE, Taylor SA, Tse MY, Pang SC, Louw JA, Vanner SJ, King WD.

Int J Mol Epidemiol Genet. 2014 May 29;5(2):120-4. eCollection 2014.

48.

Sustained neurochemical plasticity in central terminals of mouse DRG neurons following colitis.

Benson JR, Xu J, Moynes DM, Lapointe TK, Altier C, Vanner SJ, Lomax AE.

Cell Tissue Res. 2014 May;356(2):309-17. doi: 10.1007/s00441-014-1832-x. Epub 2014 Apr 9.

PMID:
24715114
49.

Response to Hassan et al.

Hookey L, Maelicharkova A, Vanner SJ, Flemming J.

Am J Gastroenterol. 2014 Apr;109(4):599-600. doi: 10.1038/ajg.2014.2. No abstract available.

PMID:
24698866
50.

Participation of interleukin 17A in neuroimmune interactions.

Moynes DM, Vanner SJ, Lomax AE.

Brain Behav Immun. 2014 Oct;41:1-9. doi: 10.1016/j.bbi.2014.03.004. Epub 2014 Mar 15.

PMID:
24642072

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