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Items: 1 to 50 of 103

1.

Does microplastic ingestion by zooplankton affect predator-prey interactions? An experimental study on larviphagy.

Van Colen C, Vanhove B, Diem A, Moens T.

Environ Pollut. 2019 Oct 23:113479. doi: 10.1016/j.envpol.2019.113479. [Epub ahead of print]

PMID:
31679869
2.

Interleukin-7 receptor blockade by an anti-CD127 monoclonal antibody in nonhuman primate kidney transplantation.

Mai HL, Nguyen TVH, Branchereau J, Poirier N, Renaudin K, Mary C, Belarif L, Minault D, Hervouet J, Le Bas-Berdardet S, Soulillou JP, Vanhove B, Blancho G, Brouard S.

Am J Transplant. 2019 Jul 25. doi: 10.1111/ajt.15543. [Epub ahead of print]

PMID:
31344323
3.
4.

SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid-derived suppressor cells.

Pengam S, Durand J, Usal C, Gauttier V, Dilek N, Martinet B, Daguin V, Mary C, Thepenier V, Teppaz G, Renaudin K, Blancho G, Vanhove B, Poirier N.

Am J Transplant. 2019 Jun 17. doi: 10.1111/ajt.15497. [Epub ahead of print]

PMID:
31207067
5.

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

Segovia M, Russo S, Jeldres M, Mahmoud YD, Perez V, Duhalde M, Charnet P, Rousset M, Victoria S, Veigas F, Louvet C, Vanhove B, Floto RA, Anegon I, Cuturi MC, Girotti MR, Rabinovich GA, Hill M.

Cancer Cell. 2019 May 13;35(5):767-781.e6. doi: 10.1016/j.ccell.2019.04.003.

6.

Selective Costimulation Blockade With Antagonist Anti-CD28 Therapeutics in Transplantation.

Vanhove B, Poirier N, Soulillou JP, Blancho G.

Transplantation. 2019 Sep;103(9):1783-1789. doi: 10.1097/TP.0000000000002740.

7.

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

Belarif L, Danger R, Kermarrec L, Nerrière-Daguin V, Pengam S, Durand T, Mary C, Kerdreux E, Gauttier V, Kucik A, Thepenier V, Martin JC, Chang C, Rahman A, Guen NS, Braudeau C, Abidi A, David G, Malard F, Takoudju C, Martinet B, Gérard N, Neveu I, Neunlist M, Coron E, MacDonald TT, Desreumaux P, Mai HL, Le Bas-Bernardet S, Mosnier JF, Merad M, Josien R, Brouard S, Soulillou JP, Blancho G, Bourreille A, Naveilhan P, Vanhove B, Poirier N.

J Clin Invest. 2019 Apr 2;129(5):1910-1925. doi: 10.1172/JCI121668. eCollection 2019 Apr 2.

8.

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.

Belarif L, Mary C, Jacquemont L, Mai HL, Danger R, Hervouet J, Minault D, Thepenier V, Nerrière-Daguin V, Nguyen E, Pengam S, Largy E, Delobel A, Martinet B, Le Bas-Bernardet S, Brouard S, Soulillou JP, Degauque N, Blancho G, Vanhove B, Poirier N.

Nat Commun. 2018 Oct 26;9(1):4483. doi: 10.1038/s41467-018-06804-y.

9.

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.

Watkins BK, Tkachev V, Furlan SN, Hunt DJ, Betz K, Yu A, Brown M, Poirier N, Zheng HB, Taraseviciute A, Colonna L, Mary C, Blancho G, Soulillou JP, Panoskaltsis-Mortari A, Sharma P, Garcia A, Strobert E, Hamby K, Garrett A, Deane T, Blazar BR, Vanhove B, Kean LS.

J Clin Invest. 2018 Aug 31;128(9):3991-4007. doi: 10.1172/JCI98793. Epub 2018 Aug 13.

10.

CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo.

Langenhorst D, Haack S, Göb S, Uri A, Lühder F, Vanhove B, Hünig T, Beyersdorf N.

Front Immunol. 2018 May 16;9:1060. doi: 10.3389/fimmu.2018.01060. eCollection 2018.

11.

A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice.

Besançon A, Goncalves T, Valette F, Mary C, Vanhove B, Chatenoud L, You S.

Diabetologia. 2018 Aug;61(8):1811-1816. doi: 10.1007/s00125-018-4638-7. Epub 2018 May 29.

PMID:
29845333
12.

Dynamic human immune and tumour cells cross-talk in PDX-humanised mice warrants checkpoint inhibitor cancer immunotherapies assessment.

Poirier N, Vanhove B.

Gut. 2018 Oct;67(10):1753-1754. doi: 10.1136/gutjnl-2018-316467. Epub 2018 Apr 26. No abstract available.

PMID:
29700013
13.

Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders.

Vanhove B, Poirier N, Fakhouri F, Laurent L, 't Hart B, Papotto PH, Rizzo LV, Zaitsu M, Issa F, Wood K, Soulillou JP, Blancho G.

Antibodies (Basel). 2017 Nov 21;6(4). pii: E19. doi: 10.3390/antib6040019. Review.

14.

CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity.

Dillinger B, Ahmadi-Erber S, Soukup K, Halfmann A, Schrom S, Vanhove B, Steinberger P, Geyeregger R, Ladisch S, Dohnal AM.

Front Immunol. 2017 Sep 20;8:1152. doi: 10.3389/fimmu.2017.01152. eCollection 2017.

15.

Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses.

Zaitsu M, Issa F, Hester J, Vanhove B, Wood KJ.

JCI Insight. 2017 Oct 5;2(19). pii: 89381. doi: 10.1172/jci.insight.89381.

16.

Rituximab-based first-line treatment of cGVHD after allogeneic SCT: results of a phase 2 study.

Malard F, Labopin M, Yakoub-Agha I, Chantepie S, Guillaume T, Blaise D, Tabrizi R, Magro L, Vanhove B, Blancho G, Moreau P, Gaugler B, Chevallier P, Mohty M.

Blood. 2017 Nov 16;130(20):2186-2195. doi: 10.1182/blood-2017-05-786137. Epub 2017 Sep 1.

PMID:
28864814
17.

Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28.

Laurent L, Le Fur A, Bloas RL, Néel M, Mary C, Moreau A, Poirier N, Vanhove B, Fakhouri F.

Eur J Immunol. 2017 Aug;47(8):1368-1376. doi: 10.1002/eji.201746923. Epub 2017 Jul 10.

18.

Inhibition of effector antigen-specific T cells by intradermal administration of heme oxygenase-1 inducers.

Simon T, Pogu J, Rémy S, Brau F, Pogu S, Maquigneau M, Fonteneau JF, Poirier N, Vanhove B, Blancho G, Piaggio E, Anegon I, Blancou P.

J Autoimmun. 2017 Jul;81:44-55. doi: 10.1016/j.jaut.2017.03.005. Epub 2017 Mar 23.

PMID:
28342735
19.

Novel CD28 antagonist mPEG PV1-Fab' mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production.

Papotto PH, Marengo EB, Sardinha LR, Carvalho KI, de Carvalho AE, Castillo-Mendez S, Jank CC, Vanhove B, Goldberg AC, Rizzo LV.

PLoS One. 2017 Mar 1;12(3):e0171822. doi: 10.1371/journal.pone.0171822. eCollection 2017.

20.

Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.

Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR.

Transplantation. 2016 Dec;100(12):2630-2639. doi: 10.1097/TP.0000000000001465.

21.

First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28.

Poirier N, Blancho G, Hiance M, Mary C, Van Assche T, Lempoels J, Ramael S, Wang W, Thepenier V, Braudeau C, Salabert N, Josien R, Anderson I, Gourley I, Soulillou JP, Coquoz D, Vanhove B.

J Immunol. 2016 Dec 15;197(12):4593-4602. Epub 2016 Nov 14.

22.

Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats.

Jung CJ, Ménoret S, Brusselle L, Tesson L, Usal C, Chenouard V, Remy S, Ouisse LH, Poirier N, Vanhove B, de Jong PJ, Anegon I.

Sci Rep. 2016 Aug 17;6:31455. doi: 10.1038/srep31455.

23.

Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection.

Ville S, Poirier N, Branchereau J, Charpy V, Pengam S, Nerriere-Daguin V, Le Bas-Bernardet S, Coulon F, Mary C, Chenouard A, Hervouet J, Minault D, Nedellec S, Renaudin K, Vanhove B, Blancho G.

J Am Soc Nephrol. 2016 Dec;27(12):3577-3588. Epub 2016 May 9.

24.

Cell Therapy for Parkinson's Disease: A Translational Approach to Assess the Role of Local and Systemic Immunosuppression.

Aron Badin R, Vadori M, Vanhove B, Nerriere-Daguin V, Naveilhan P, Neveu I, Jan C, Lévèque X, Venturi E, Mermillod P, Van Camp N, Dollé F, Guillermier M, Denaro L, Manara R, Citton V, Simioni P, Zampieri P, D'avella D, Rubello D, Fante F, Boldrin M, De Benedictis GM, Cavicchioli L, Sgarabotto D, Plebani M, Stefani AL, Brachet P, Blancho G, Soulillou JP, Hantraye P, Cozzi E.

Am J Transplant. 2016 Jul;16(7):2016-29. doi: 10.1111/ajt.13704. Epub 2016 Mar 3.

25.

Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates.

Poirier N, Chevalier M, Mary C, Hervouet J, Minault D, Baker P, Ville S, Le Bas-Bernardet S, Dilek N, Belarif L, Cassagnau E, Scobie L, Blancho G, Vanhove B.

J Immunol. 2016 Jan 1;196(1):274-83. doi: 10.4049/jimmunol.1501810. Epub 2015 Nov 23.

26.

Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis.

Vierboom MP, Breedveld E, Kap YS, Mary C, Poirier N, 't Hart BA, Vanhove B.

Clin Exp Immunol. 2016 Mar;183(3):405-18. doi: 10.1111/cei.12739. Epub 2015 Dec 16.

27.

Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates.

Poirier N, Chevalier M, Mary C, Hervouet J, Minault D, Le Bas-Bernardet S, Belarif L, Daguin V, Cassagnau E, Vanhove B, Blancho G.

Exp Dermatol. 2016 Mar;25(3):233-4. doi: 10.1111/exd.12891. Epub 2016 Feb 10. No abstract available.

PMID:
26513536
28.

Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?

Ville S, Poirier N, Blancho G, Vanhove B.

Front Immunol. 2015 Aug 10;6:411. doi: 10.3389/fimmu.2015.00411. eCollection 2015. Review.

29.

Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.

Louveau A, Nerrière-Daguin V, Vanhove B, Naveilhan P, Neunlist M, Nicot A, Boudin H.

Glia. 2015 Dec;63(12):2298-312. doi: 10.1002/glia.22894. Epub 2015 Jul 27.

PMID:
26212105
30.

Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis.

Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart BA, Vanhove B.

J Immunol. 2015 Jul 15;195(2):749. doi: 10.4049/jimmunol.1501150. No abstract available.

31.

Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons.

Le Bas-Bernardet S, Tillou X, Branchereau J, Dilek N, Poirier N, Châtelais M, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Takeuchi Y, Diswall M, Breimer ME, Klar N, Daha MR, Simioni P, Robson SC, Nottle MB, Salvaris EJ, Cowan PJ, d'Apice AJ, Sachs DH, Yamada K, Lagutina I, Duchi R, Perota A, Lazzari G, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G.

Am J Transplant. 2015 Feb;15(2):358-70. doi: 10.1111/ajt.12988.

32.

Selective blockade of CD28-mediated T cell costimulation protects rhesus monkeys against acute fatal experimental autoimmune encephalomyelitis.

Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Crossan CL, Scobie L, 't Hart BA, Vanhove B.

J Immunol. 2015 Feb 15;194(4):1454-66. doi: 10.4049/jimmunol.1402563. Epub 2015 Jan 14. Erratum in: J Immunol. 2015 Jul 15;195(2):749. Crossan, Claire L [added].

33.

FR104, an antagonist anti-CD28 monovalent fab' antibody, prevents alloimmunization and allows calcineurin inhibitor minimization in nonhuman primate renal allograft.

Poirier N, Dilek N, Mary C, Ville S, Coulon F, Branchereau J, Tillou X, Charpy V, Pengam S, Nerriere-Daguin V, Hervouet J, Minault D, Le Bas-Bernardet S, Renaudin K, Vanhove B, Blancho G.

Am J Transplant. 2015 Jan;15(1):88-100. doi: 10.1111/ajt.12964. Epub 2014 Dec 8.

34.

Local control of the host immune response performed with mesenchymal stem cells: perspectives for functional intracerebral xenotransplantation.

Lévêque X, Mathieux E, Nerrière-Daguin V, Thinard R, Kermarrec L, Durand T, Haudebourg T, Vanhove B, Lescaudron L, Neveu I, Naveilhan P.

J Cell Mol Med. 2015 Jan;19(1):124-34. doi: 10.1111/jcmm.12414. Epub 2014 Oct 14.

35.

hCTLA4-Ig transgene expression in keratocytes modulates rejection of corneal xenografts in a pig to non-human primate anterior lamellar keratoplasty model.

Vabres B, Le Bas-Bernardet S, Riochet D, Chérel Y, Minault D, Hervouet J, Ducournau Y, Moreau A, Daguin V, Coulon F, Pallier A, Brouard S, Robson SC, Nottle MB, Cowan PJ, Venturi E, Mermillod P, Brachet P, Galli C, Lagutina I, Duchi R, Bach JM, Blancho G, Soulillou JP, Vanhove B.

Xenotransplantation. 2014 Sep-Oct;21(5):431-43. doi: 10.1111/xen.12107. Epub 2014 Jul 8.

PMID:
25040113
36.

Advantages of Papio anubis for preclinical testing of immunotoxicity of candidate therapeutic antagonist antibodies targeting CD28.

Poirier N, Mary C, Le Bas-Bernardet S, Daguin V, Belarif L, Chevalier M, Hervouet J, Minault D, Ville S, Charpy V, Blancho G, Vanhove B.

MAbs. 2014 May-Jun;6(3):697-707. doi: 10.4161/mabs.28375. Epub 2014 Mar 5.

37.

IL-7 receptor blockade following T cell depletion promotes long-term allograft survival.

Mai HL, Boeffard F, Longis J, Danger R, Martinet B, Haspot F, Vanhove B, Brouard S, Soulillou JP.

J Clin Invest. 2014 Apr;124(4):1723-33. doi: 10.1172/JCI66287. Epub 2014 Feb 24.

38.

Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.

Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clémenceau B, Blancho G, Vanhove B.

PLoS One. 2013 Dec 23;8(12):e83139. doi: 10.1371/journal.pone.0083139. eCollection 2013.

39.

Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts.

Scobie L, Padler-Karavani V, Le Bas-Bernardet S, Crossan C, Blaha J, Matouskova M, Hector RD, Cozzi E, Vanhove B, Charreau B, Blancho G, Bourdais L, Tallacchini M, Ribes JM, Yu H, Chen X, Kracikova J, Broz L, Hejnar J, Vesely P, Takeuchi Y, Varki A, Soulillou JP.

J Immunol. 2013 Sep 15;191(6):2907-15. doi: 10.4049/jimmunol.1301195. Epub 2013 Aug 14.

40.

Antagonist properties of monoclonal antibodies targeting human CD28: role of valency and the heavy-chain constant domain.

Mary C, Coulon F, Poirier N, Dilek N, Martinet B, Blancho G, Vanhove B.

MAbs. 2013 Jan-Feb;5(1):47-55. doi: 10.4161/mabs.22697. Epub 2012 Dec 5.

41.

Reply to "Biologics in organ transplantation".

Vanhove B, Azimzadeh A.

Transpl Int. 2013 Apr;26(4):e25. doi: 10.1111/tri.12009. Epub 2012 Nov 12. No abstract available.

42.

Gene transfer of human CD40Ig does not prevent rejection in a non-human primate kidney allotransplantation model.

Angin M, Poirier N, Dilek N, Le Guiner C, Toromanoff A, Blancher A, Cherel Y, Deschamps JY, Tillou X, Renaudin K, Minault D, Hervouet J, Blancho G, Vanhove B, Anegon I, Le Mauff B.

Transpl Immunol. 2012 Dec;27(4):139-45. doi: 10.1016/j.trim.2012.10.004. Epub 2012 Oct 23.

PMID:
23098770
43.

Expression of heme oxygenase-1 in neural stem/progenitor cells as a potential mechanism to evade host immune response.

Bonnamain V, Mathieux E, Thinard R, Thébault P, Nerrière-Daguin V, Lévêque X, Anegon I, Vanhove B, Neveu I, Naveilhan P.

Stem Cells. 2012 Oct;30(10):2342-53. doi: 10.1002/stem.1199.

44.

Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance.

Dilek N, Vuillefroy de Silly R, Blancho G, Vanhove B.

Front Immunol. 2012 Jul 17;3:208. doi: 10.3389/fimmu.2012.00208. eCollection 2012.

45.

Preclinical efficacy and immunological safety of FR104, an antagonist anti-CD28 monovalent Fab' antibody.

Poirier N, Mary C, Dilek N, Hervouet J, Minault D, Blancho G, Vanhove B.

Am J Transplant. 2012 Oct;12(10):2630-40. doi: 10.1111/j.1600-6143.2012.04164.x. Epub 2012 Jul 3.

46.

CD28-specific immunomodulating antibodies: what can be learned from experimental models?

Poirier N, Blancho G, Vanhove B.

Am J Transplant. 2012 Jul;12(7):1682-90. doi: 10.1111/j.1600-6143.2012.04032.x. Epub 2012 Apr 4. Review.

47.

Control of transplant tolerance and intragraft regulatory T cell localization by myeloid-derived suppressor cells and CCL5.

Dilek N, Poirier N, Usal C, Martinet B, Blancho G, Vanhove B.

J Immunol. 2012 May 1;188(9):4209-16. doi: 10.4049/jimmunol.1101512. Epub 2012 Mar 26.

48.

Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.

Vuillefroy de Silly R, Coulon F, Poirier N, Jovanovic V, Brouard S, Ferchaud-Roucher V, Blancho G, Vanhove B.

Blood. 2012 Mar 15;119(11):2633-43. doi: 10.1182/blood-2011-04-350546. Epub 2012 Jan 19.

PMID:
22262763
49.

Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons.

Le Bas-Bernardet S, Tillou X, Poirier N, Dilek N, Chatelais M, Devallière J, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Cowan PJ, d'Apice AJ, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G.

Transplant Proc. 2011 Nov;43(9):3426-30. doi: 10.1016/j.transproceed.2011.09.024.

PMID:
22099813
50.

TNF blockade abrogates the induction of T cell-dependent humoral responses in an allotransplantation model.

FrancoSalinas G, Mai HL, Jovanovic V, Moizant F, Vanhove B, Boeffard F, Usal C, Tak PP, Soulillou JP, Baeten D, Brouard S.

J Leukoc Biol. 2011 Aug;90(2):367-75. doi: 10.1189/jlb.0710392. Epub 2011 May 11.

PMID:
21562051

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