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Items: 1 to 50 of 947

1.

Piezo Ion Channels in Cardiovascular Mechanobiology.

Douguet D, Patel A, Xu A, Vanhoutte PM, Honoré E.

Trends Pharmacol Sci. 2019 Dec;40(12):956-970. doi: 10.1016/j.tips.2019.10.002. Epub 2019 Nov 5. Review.

PMID:
31704174
2.

Vascular adenosine monophosphate-activated protein kinase: Enhancer, brake or both?

Chen H, Vanhoutte PM, Leung SWS.

Basic Clin Pharmacol Toxicol. 2019 Oct 31. doi: 10.1111/bcpt.13357. [Epub ahead of print] Review.

PMID:
31671245
3.

Hypoxic augmentation: The tale of a strange contraction.

Vanhoutte PM, Leung SWS.

Basic Clin Pharmacol Toxicol. 2019 Jul 16. doi: 10.1111/bcpt.13295. [Epub ahead of print] Review.

PMID:
31310708
4.

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues.

Konja D, Luo C, Sun WY, Yang K, Man AWC, Xu A, Vanhoutte PM, Wang Y.

J Vis Exp. 2019 Jun 3;(148). doi: 10.3791/59688.

PMID:
31205306
5.

Acute activation of endothelial AMPK surprisingly inhibits endothelium-dependent hyperpolarization-like relaxations in rat mesenteric arteries.

Chen H, Vanhoutte PM, Leung SWS.

Br J Pharmacol. 2019 Aug;176(16):2905-2921. doi: 10.1111/bph.14716. Epub 2019 Jul 4.

PMID:
31116877
6.

Endothelial muscarinic M3 -receptors: A Σ-target?

Vanhoutte PM.

Acta Physiol (Oxf). 2019 May;226(1):e13273. doi: 10.1111/apha.13273. Epub 2019 Mar 29. No abstract available.

PMID:
30848554
7.

Periarterial fat from two human vascular beds is not a source of aldosterone to promote vasoconstriction.

Assersen KB, Jensen PS, Briones AM, Rasmussen LM, Marcussen N, Toft A, Vanhoutte PM, Jensen BL, Hansen PBL.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1670-F1682. doi: 10.1152/ajprenal.00391.2018. Epub 2018 Oct 3.

8.

The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.

Ydegaard R, Andersen H, Oxlund CS, Jacobsen IA, Hansen PBL, Jürgensen JF, Peluso AA, Vanhoutte PM, Staehr M, Svenningsen P, Jensen BL.

Acta Physiol (Oxf). 2019 Jan;225(1):e13189. doi: 10.1111/apha.13189. Epub 2018 Oct 11.

PMID:
30240139
9.

Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury.

Sun WY, Bai B, Luo C, Yang K, Li D, Wu D, Félétou M, Villeneuve N, Zhou Y, Yang J, Xu A, Vanhoutte PM, Wang Y.

JCI Insight. 2018 Sep 6;3(17). pii: 120196. doi: 10.1172/jci.insight.120196. eCollection 2018 Sep 6.

10.

Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.

Guo Y, Xu C, Man AWC, Bai B, Luo C, Huang Y, Xu A, Vanhoutte PM, Wang Y.

Cardiovasc Res. 2019 Mar 1;115(3):678-690. doi: 10.1093/cvr/cvy212.

PMID:
30165439
11.

Low but not high frequency of intermittent hypoxia suppresses endothelium-dependent, oxidative stress-mediated contractions in carotid arteries of obese mice.

Lee MYK, Ge G, Fung ML, Vanhoutte PM, Mak JCW, Ip MSM.

J Appl Physiol (1985). 2018 Nov 1;125(5):1384-1395. doi: 10.1152/japplphysiol.00224.2018. Epub 2018 Aug 9.

12.

Activation of NQO-1 mediates the augmented contractions of isolated arteries due to biased activity of soluble guanylyl cyclase in their smooth muscle.

Detremmerie CMS, Leung SWS, Vanhoutte PM.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Nov;391(11):1221-1235. doi: 10.1007/s00210-018-1548-7. Epub 2018 Jul 30.

PMID:
30062552
14.

EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia.

Ying F, Cai Y, Wong HK, Chen XY, Huang IB, Vanhoutte PM, Xia Z, Xu A, Tang EHC.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1029-1040. doi: 10.1016/j.bbalip.2018.06.003. Epub 2018 Jun 8.

PMID:
29890224
15.

Apolipoprotein E favours the blunting by high-fat diet of prostacyclin receptor activation in the mouse aorta.

Cheng Y, Vanhoutte PM, Leung SWS.

Br J Pharmacol. 2018 Sep;175(17):3453-3469. doi: 10.1111/bph.14386. Epub 2018 Jul 22.

16.

Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome.

Tong KL, Mahmood Zuhdi AS, Wan Ahmad WA, Vanhoutte PM, de Magalhaes JP, Mustafa MR, Wong PF.

Int J Mol Sci. 2018 May 15;19(5). pii: E1467. doi: 10.3390/ijms19051467.

17.

Nitric Oxide: From Good to Bad.

Vanhoutte PM.

Ann Vasc Dis. 2018 Mar 25;11(1):41-51. doi: 10.3400/avd.ra.17-00134. Review.

18.

Deletion of Rap1 disrupts redox balance and impairs endothelium-dependent relaxations.

Wong KHK, Cai Y, Ying F, Chen X, Vanhoutte PM, Tang EHC.

J Mol Cell Cardiol. 2018 Feb;115:1-9. doi: 10.1016/j.yjmcc.2017.12.009. Epub 2017 Dec 23.

PMID:
29277598
19.

Paeonol Attenuates LPS-Induced Endothelial Dysfunction and Apoptosis by Inhibiting BMP4 and TLR4 Signaling Simultaneously but Independently.

Choy KW, Lau YS, Murugan D, Vanhoutte PM, Mustafa MR.

J Pharmacol Exp Ther. 2018 Mar;364(3):420-432. doi: 10.1124/jpet.117.245217. Epub 2017 Dec 19.

PMID:
29259041
20.

L-arginine and Arginase Products Potentiate Dexmedetomidine-induced Contractions in the Rat Aorta.

Wong ESW, Man RYK, Ng KFJ, Leung SWS, Vanhoutte PM.

Anesthesiology. 2018 Mar;128(3):564-573. doi: 10.1097/ALN.0000000000002032.

PMID:
29251642
21.

Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.

Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y.

ESC Heart Fail. 2017 Nov;4(4):563-575. doi: 10.1002/ehf2.12183. Epub 2017 Jun 27.

22.

Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.

Doytcheva P, Bächler T, Tarasco E, Marzolla V, Engeli M, Pellegrini G, Stivala S, Rohrer L, Tona F, Camici GG, Vanhoutte PM, Matter CM, Lutz TA, Lüscher TF, Osto E.

J Am Heart Assoc. 2017 Nov 14;6(11). pii: e006441. doi: 10.1161/JAHA.117.006441.

23.

Paradoxical lack of increase in endothelin-1 levels in obese mice - possible role of endothelin-B receptors.

Baretella O, Chung SK, Xu A, Vanhoutte PM.

Acta Pharmacol Sin. 2017 Dec;38(12):1699-1700. doi: 10.1038/aps.2017.155. Epub 2017 Nov 9. No abstract available.

24.

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

Thuesen AD, Andersen K, Lyngsø KS, Burton M, Brasch-Andersen C, Vanhoutte PM, Hansen PBL.

Pflugers Arch. 2018 Feb;470(2):355-365. doi: 10.1007/s00424-017-2068-x. Epub 2017 Oct 29.

PMID:
29082441
25.

Corrigendum to 'Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats' [Eur. J. Pharmacol. 773 (2016) 78-84].

Mokhtar SS, Vanhoutte PM, Leung SWS, Suppian R, Yusof MI, Rasool AHG.

Eur J Pharmacol. 2017 Oct 5;812:264. doi: 10.1016/j.ejphar.2017.08.032. No abstract available.

PMID:
28915977
26.

Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone.

Detremmerie C, Vanhoutte PM, Leung S.

Acta Pharm Sin B. 2017 Jul;7(4):401-408. doi: 10.1016/j.apsb.2017.06.003. Epub 2017 Jul 3. Review.

27.

Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice.

Ling WC, Mustafa MR, Vanhoutte PM, Murugan DD.

Vascul Pharmacol. 2018 Mar;102:11-20. doi: 10.1016/j.vph.2017.05.003. Epub 2017 May 26.

PMID:
28552746
28.

Prostaglandin E2 regulates renal function in C57/BL6 mouse with 5/6 nephrectomy.

Jin J, Tang Q, Li Z, Zhao Z, Zhang Z, Lu L, Zhu T, Vanhoutte PM, Leung SW, Tu R, Shi Y.

Life Sci. 2017 Apr 1;174:68-76. doi: 10.1016/j.lfs.2017.03.001. Epub 2017 Mar 2.

PMID:
28263803
29.

12th International Symposium for Mechanisms of Vasodilatation: Celebrating the 30th Anniversary of the Announcement of NO as a Vasodilator Molecule.

Miller VM, Webb RC, Vanhoutte PM.

J Cardiovasc Pharmacol. 2017 May;69(5):245-247. doi: 10.1097/FJC.0000000000000478. No abstract available.

PMID:
28221269
30.

Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice.

Baretella O, Chung SK, Xu A, Vanhoutte PM.

Acta Pharmacol Sin. 2017 Apr;38(4):498-512. doi: 10.1038/aps.2016.138. Epub 2017 Feb 20.

31.

Macro- and microvascular endothelial dysfunction in diabetes.

Shi Y, Vanhoutte PM.

J Diabetes. 2017 May;9(5):434-449. doi: 10.1111/1753-0407.12521. Epub 2017 Mar 1. Review.

PMID:
28044409
32.

An old wheel gets a new CART ….

Vanhoutte PM.

Eur Heart J. 2017 Feb 14;38(7):497-499. doi: 10.1093/eurheartj/ehw508. No abstract available.

PMID:
28039337
33.

Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1.

Bai B, Man AW, Yang K, Guo Y, Xu C, Tse HF, Han W, Bloksgaard M, De Mey JG, Vanhoutte PM, Xu A, Wang Y.

Oncotarget. 2016 Jun 28;7(26):39065-39081. doi: 10.18632/oncotarget.9687.

34.

Erratum. APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice. Diabetes 2011;60:3044-3054.

Wang Y, Cheng KK, Lam KS, Wu D, Wang Y, Huang Y, Vanhoutte PM, Sweeney G, Li Y, Xu A.

Diabetes. 2016 Oct;65(10):3219. doi: 10.2337/db16-er10c. No abstract available.

35.

Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway. Diabetes 2010;59:2949-2959.

Chang J, Li Y, Huang Y, Lam KS, Hoo RL, Wong WT, Cheng KK, Wang Y, Vanhoutte PM, Xu A.

Diabetes. 2016 Oct;65(10):3219. doi: 10.2337/db16-er10b. No abstract available.

36.

Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR.

Ling WC, Murugan DD, Lau YS, Vanhoutte PM, Mustafa MR.

Sci Rep. 2016 Sep 12;6:33048. doi: 10.1038/srep33048.

37.

Endothelium-Dependent Contractions: Prostacyclin and Endothelin-1, Partners in Crime?

Baretella O, Vanhoutte PM.

Adv Pharmacol. 2016;77:177-208. doi: 10.1016/bs.apha.2016.04.006. Epub 2016 Jun 6.

PMID:
27451098
38.

Thirty Years of Saying NO: Sources, Fate, Actions, and Misfortunes of the Endothelium-Derived Vasodilator Mediator.

Vanhoutte PM, Zhao Y, Xu A, Leung SW.

Circ Res. 2016 Jul 8;119(2):375-96. doi: 10.1161/CIRCRESAHA.116.306531. Review.

PMID:
27390338
39.

Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production.

Detremmerie CM, Chen Z, Li Z, Alkharfy KM, Leung SW, Xu A, Gao Y, Vanhoutte PM.

J Pharmacol Exp Ther. 2016 Sep;358(3):558-68. doi: 10.1124/jpet.116.234153. Epub 2016 Jun 22.

PMID:
27335436
40.

Endothelium-dependent hyperpolarizations in health and disease.

Hansen PB, De Mey JG, Vanhoutte PM.

Acta Physiol (Oxf). 2017 Jan;219(1):97-99. doi: 10.1111/apha.12716. Epub 2016 Jun 16. No abstract available.

PMID:
27199187
41.

Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe-/- Mice.

Li J, Lin S, Vanhoutte PM, Woo CW, Xu A.

Circulation. 2016 Jun 14;133(24):2434-46. doi: 10.1161/CIRCULATIONAHA.115.019645. Epub 2016 Apr 25.

PMID:
27143680
42.

Regenerated Endothelium and Its Senescent Response to Aggregating Platelets.

Vanhoutte PM.

Circ J. 2016;80(4):783-90. doi: 10.1253/circj.CJ-16-0179. Epub 2016 Mar 10. Review.

43.

Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats.

Mokhtar SS, Vanhoutte PM, Leung SW, Suppian R, Yusof MI, Rasool AH.

Eur J Pharmacol. 2016 Feb 15;773:78-84. doi: 10.1016/j.ejphar.2016.01.013. Epub 2016 Jan 26. Erratum in: Eur J Pharmacol. 2017 Oct 5;812:264.

PMID:
26825543
44.

Endothelium-dependent hyperpolarizations: Quo vadis?

Félétou M, Vanhoutte PM.

Acta Physiol (Oxf). 2017 Jan;219(1):100-107. doi: 10.1111/apha.12657. Epub 2016 Feb 12. No abstract available.

PMID:
26820582
45.

Endothelium dependent hyperpolarization-type relaxation compensates for attenuated nitric oxide-mediated responses in subcutaneous arteries of diabetic patients.

Mokhtar SS, Vanhoutte PM, Leung SW, Yusof MI, Wan Sulaiman WA, Mat Saad AZ, Suppian R, Rasool AH.

Nitric Oxide. 2016 Feb 29;53:35-44. doi: 10.1016/j.niox.2015.12.007. Epub 2016 Jan 6.

PMID:
26768833
46.

3',5'-cIMP as Potential Second Messenger in the Vascular Wall.

Leung SWS, Gao Y, Vanhoutte PM.

Handb Exp Pharmacol. 2017;238:209-228. doi: 10.1007/164_2015_39. Review.

PMID:
26721675
47.

Endothelial dysfunction and vascular disease - a 30th anniversary update.

Vanhoutte PM, Shimokawa H, Feletou M, Tang EH.

Acta Physiol (Oxf). 2017 Jan;219(1):22-96. doi: 10.1111/apha.12646. Epub 2016 Jan 25. Review.

PMID:
26706498
48.

Toll-like receptors mediating vascular malfunction: Lessons from receptor subtypes.

Wang Y, Song E, Bai B, Vanhoutte PM.

Pharmacol Ther. 2016 Feb;158:91-100. doi: 10.1016/j.pharmthera.2015.12.005. Epub 2015 Dec 15. Review.

PMID:
26702901
49.

Endothelial Lessons.

Vanhoutte PM.

Curr Vasc Pharmacol. 2016;14(2):175-80. Review.

PMID:
26638800
50.

Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter?

Leung SW, Vanhoutte PM.

Acta Physiol (Oxf). 2017 Jan;219(1):108-123. doi: 10.1111/apha.12628. Epub 2015 Dec 1. Review.

PMID:
26548576

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