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Items: 1 to 50 of 1031

1.

Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice.

Rosenstand K, Andersen K, Terp R, Gennemark P, Ellman DG, Reznichenko A, Lambertsen KL, Vanhoutte PM, Hansen PBL, Svenningsen P.

J Physiol Biochem. 2020 Feb;76(1):135-145. doi: 10.1007/s13105-020-00728-2. Epub 2020 Feb 3.

PMID:
32016773
2.

From Signaling Molecules to Circuits and Behaviors: Cell-Type-Specific Adaptations to Psychostimulant Exposure in the Striatum.

Salery M, Trifilieff P, Caboche J, Vanhoutte P.

Biol Psychiatry. 2019 Nov 9. pii: S0006-3223(19)31849-9. doi: 10.1016/j.biopsych.2019.11.001. [Epub ahead of print] Review.

3.

Cardiomyocyte-Specific JunD Overexpression Increases Infarct Size following Ischemia/Reperfusion Cardiac Injury by Downregulating Sirt3.

Akhmedov A, Montecucco F, Costantino S, Vdovenko D, Schaub Clerigué A, Gaul DS, Burger F, Roth A, Carbone F, Liberale L, Amrollahi-Sharifabadi M, Vellone VG, Eriksson U, Matter CM, Crowe LA, Vallée JP, Paneni F, Vanhoutte PM, Camici GG, Mach F, Lüscher TF.

Thromb Haemost. 2020 Jan;120(1):168-180. doi: 10.1055/s-0039-3400299. Epub 2019 Dec 13.

PMID:
31858519
4.

Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.

Yildirim F, Ng CW, Kappes V, Ehrenberger T, Rigby SK, Stivanello V, Gipson TA, Soltis AR, Vanhoutte P, Caboche J, Housman DE, Fraenkel E.

Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24840-24851. doi: 10.1073/pnas.1908113116. Epub 2019 Nov 19.

PMID:
31744868
5.

Piezo Ion Channels in Cardiovascular Mechanobiology.

Douguet D, Patel A, Xu A, Vanhoutte PM, Honoré E.

Trends Pharmacol Sci. 2019 Dec;40(12):956-970. doi: 10.1016/j.tips.2019.10.002. Epub 2019 Nov 5. Review.

PMID:
31704174
6.

Vascular adenosine monophosphate-activated protein kinase: Enhancer, brake or both?

Chen H, Vanhoutte PM, Leung SWS.

Basic Clin Pharmacol Toxicol. 2019 Oct 31. doi: 10.1111/bcpt.13357. [Epub ahead of print] Review.

PMID:
31671245
7.

Hypoxic augmentation: The tale of a strange contraction.

Vanhoutte PM, Leung SWS.

Basic Clin Pharmacol Toxicol. 2019 Jul 16. doi: 10.1111/bcpt.13295. [Epub ahead of print] Review.

PMID:
31310708
8.

CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease.

Kacher R, Lamazière A, Heck N, Kappes V, Mounier C, Despres G, Dembitskaya Y, Perrin E, Christaller W, Sasidharan Nair S, Messent V, Cartier N, Vanhoutte P, Venance L, Saudou F, Néri C, Caboche J, Betuing S.

Brain. 2019 Aug 1;142(8):2432-2450. doi: 10.1093/brain/awz174.

PMID:
31286142
9.

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues.

Konja D, Luo C, Sun WY, Yang K, Man AWC, Xu A, Vanhoutte PM, Wang Y.

J Vis Exp. 2019 Jun 3;(148). doi: 10.3791/59688.

PMID:
31205306
10.

Acute activation of endothelial AMPK surprisingly inhibits endothelium-dependent hyperpolarization-like relaxations in rat mesenteric arteries.

Chen H, Vanhoutte PM, Leung SWS.

Br J Pharmacol. 2019 Aug;176(16):2905-2921. doi: 10.1111/bph.14716. Epub 2019 Jul 4.

PMID:
31116877
11.

Endothelial muscarinic M3 -receptors: A Σ-target?

Vanhoutte PM.

Acta Physiol (Oxf). 2019 May;226(1):e13273. doi: 10.1111/apha.13273. Epub 2019 Mar 29. No abstract available.

PMID:
30848554
12.

Modulation and functions of dopamine receptor heteromers in drugs of abuse-induced adaptations.

Andrianarivelo A, Saint-Jour E, Walle R, Trifilieff P, Vanhoutte P.

Neuropharmacology. 2019 Jul 1;152:42-50. doi: 10.1016/j.neuropharm.2018.12.003. Epub 2018 Dec 4. Review.

13.

Periarterial fat from two human vascular beds is not a source of aldosterone to promote vasoconstriction.

Assersen KB, Jensen PS, Briones AM, Rasmussen LM, Marcussen N, Toft A, Vanhoutte PM, Jensen BL, Hansen PBL.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1670-F1682. doi: 10.1152/ajprenal.00391.2018. Epub 2018 Oct 3.

14.

The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.

Ydegaard R, Andersen H, Oxlund CS, Jacobsen IA, Hansen PBL, Jürgensen JF, Peluso AA, Vanhoutte PM, Staehr M, Svenningsen P, Jensen BL.

Acta Physiol (Oxf). 2019 Jan;225(1):e13189. doi: 10.1111/apha.13189. Epub 2018 Oct 11.

PMID:
30240139
15.

Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury.

Sun WY, Bai B, Luo C, Yang K, Li D, Wu D, Félétou M, Villeneuve N, Zhou Y, Yang J, Xu A, Vanhoutte PM, Wang Y.

JCI Insight. 2018 Sep 6;3(17). pii: 120196. doi: 10.1172/jci.insight.120196. eCollection 2018 Sep 6.

16.

Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.

Guo Y, Xu C, Man AWC, Bai B, Luo C, Huang Y, Xu A, Vanhoutte PM, Wang Y.

Cardiovasc Res. 2019 Mar 1;115(3):678-690. doi: 10.1093/cvr/cvy212.

PMID:
30165439
17.

CYP46A1 protects against NMDA-mediated excitotoxicity in Huntington's disease: Analysis of lipid raft content.

Boussicault L, Kacher R, Lamazière A, Vanhoutte P, Caboche J, Betuing S, Potier MC.

Biochimie. 2018 Oct;153:70-79. doi: 10.1016/j.biochi.2018.07.019. Epub 2018 Aug 11.

PMID:
30107216
18.

Low but not high frequency of intermittent hypoxia suppresses endothelium-dependent, oxidative stress-mediated contractions in carotid arteries of obese mice.

Lee MYK, Ge G, Fung ML, Vanhoutte PM, Mak JCW, Ip MSM.

J Appl Physiol (1985). 2018 Nov 1;125(5):1384-1395. doi: 10.1152/japplphysiol.00224.2018. Epub 2018 Aug 9.

19.

Dysregulated Neurotransmission induces Trans-synaptic degeneration in reconstructed Neuronal Networks.

Deleglise B, Lassus B, Soubeyre V, Doulazmi M, Brugg B, Vanhoutte P, Peyrin JM.

Sci Rep. 2018 Aug 2;8(1):11596. doi: 10.1038/s41598-018-29918-1.

20.

Activation of NQO-1 mediates the augmented contractions of isolated arteries due to biased activity of soluble guanylyl cyclase in their smooth muscle.

Detremmerie CMS, Leung SWS, Vanhoutte PM.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Nov;391(11):1221-1235. doi: 10.1007/s00210-018-1548-7. Epub 2018 Jul 30.

PMID:
30062552
22.

EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia.

Ying F, Cai Y, Wong HK, Chen XY, Huang IB, Vanhoutte PM, Xia Z, Xu A, Tang EHC.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1029-1040. doi: 10.1016/j.bbalip.2018.06.003. Epub 2018 Jun 8.

PMID:
29890224
23.

Apolipoprotein E favours the blunting by high-fat diet of prostacyclin receptor activation in the mouse aorta.

Cheng Y, Vanhoutte PM, Leung SWS.

Br J Pharmacol. 2018 Sep;175(17):3453-3469. doi: 10.1111/bph.14386. Epub 2018 Jul 22.

24.

Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome.

Tong KL, Mahmood Zuhdi AS, Wan Ahmad WA, Vanhoutte PM, de Magalhaes JP, Mustafa MR, Wong PF.

Int J Mol Sci. 2018 May 15;19(5). pii: E1467. doi: 10.3390/ijms19051467.

25.

Nitric Oxide: From Good to Bad.

Vanhoutte PM.

Ann Vasc Dis. 2018 Mar 25;11(1):41-51. doi: 10.3400/avd.ra.17-00134. Review.

26.

Deletion of Rap1 disrupts redox balance and impairs endothelium-dependent relaxations.

Wong KHK, Cai Y, Ying F, Chen X, Vanhoutte PM, Tang EHC.

J Mol Cell Cardiol. 2018 Feb;115:1-9. doi: 10.1016/j.yjmcc.2017.12.009. Epub 2017 Dec 23.

PMID:
29277598
27.

Paeonol Attenuates LPS-Induced Endothelial Dysfunction and Apoptosis by Inhibiting BMP4 and TLR4 Signaling Simultaneously but Independently.

Choy KW, Lau YS, Murugan D, Vanhoutte PM, Mustafa MR.

J Pharmacol Exp Ther. 2018 Mar;364(3):420-432. doi: 10.1124/jpet.117.245217. Epub 2017 Dec 19.

PMID:
29259041
28.

L-arginine and Arginase Products Potentiate Dexmedetomidine-induced Contractions in the Rat Aorta.

Wong ESW, Man RYK, Ng KFJ, Leung SWS, Vanhoutte PM.

Anesthesiology. 2018 Mar;128(3):564-573. doi: 10.1097/ALN.0000000000002032.

PMID:
29251642
29.

High dengue virus load differentially modulates human microvascular endothelial barrier function during early infection.

Soe HJ, Khan AM, Manikam R, Samudi Raju C, Vanhoutte P, Sekaran SD.

J Gen Virol. 2017 Dec;98(12):2993-3007. doi: 10.1099/jgv.0.000981. Epub 2017 Nov 24.

PMID:
29182510
30.

Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.

Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y.

ESC Heart Fail. 2017 Nov;4(4):563-575. doi: 10.1002/ehf2.12183. Epub 2017 Jun 27.

31.

Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.

Doytcheva P, Bächler T, Tarasco E, Marzolla V, Engeli M, Pellegrini G, Stivala S, Rohrer L, Tona F, Camici GG, Vanhoutte PM, Matter CM, Lutz TA, Lüscher TF, Osto E.

J Am Heart Assoc. 2017 Nov 14;6(11). pii: e006441. doi: 10.1161/JAHA.117.006441.

32.

Paradoxical lack of increase in endothelin-1 levels in obese mice - possible role of endothelin-B receptors.

Baretella O, Chung SK, Xu A, Vanhoutte PM.

Acta Pharmacol Sin. 2017 Dec;38(12):1699-1700. doi: 10.1038/aps.2017.155. Epub 2017 Nov 9. No abstract available.

33.

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

Thuesen AD, Andersen K, Lyngsø KS, Burton M, Brasch-Andersen C, Vanhoutte PM, Hansen PBL.

Pflugers Arch. 2018 Feb;470(2):355-365. doi: 10.1007/s00424-017-2068-x. Epub 2017 Oct 29.

PMID:
29082441
34.

Cocaine increases dopaminergic connectivity in the nucleus accumbens.

Dos Santos M, Cahill EN, Bo GD, Vanhoutte P, Caboche J, Giros B, Heck N.

Brain Struct Funct. 2018 Mar;223(2):913-923. doi: 10.1007/s00429-017-1532-x. Epub 2017 Oct 12.

PMID:
29027032
35.

Corrigendum to 'Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats' [Eur. J. Pharmacol. 773 (2016) 78-84].

Mokhtar SS, Vanhoutte PM, Leung SWS, Suppian R, Yusof MI, Rasool AHG.

Eur J Pharmacol. 2017 Oct 5;812:264. doi: 10.1016/j.ejphar.2017.08.032. No abstract available.

PMID:
28915977
36.

Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.

Erdozain AM, De Gois S, Bernard V, Gorgievski V, Pietrancosta N, Dumas S, Macedo CE, Vanhoutte P, Ortega JE, Meana JJ, Tzavara ET, Vialou V, Giros B.

Neuropsychopharmacology. 2018 Apr;43(5):1041-1051. doi: 10.1038/npp.2017.217. Epub 2017 Sep 14.

37.

Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone.

Detremmerie C, Vanhoutte PM, Leung S.

Acta Pharm Sin B. 2017 Jul;7(4):401-408. doi: 10.1016/j.apsb.2017.06.003. Epub 2017 Jul 3. Review.

38.

Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice.

Ling WC, Mustafa MR, Vanhoutte PM, Murugan DD.

Vascul Pharmacol. 2018 Mar;102:11-20. doi: 10.1016/j.vph.2017.05.003. Epub 2017 May 26.

PMID:
28552746
39.

Rapid Synaptogenesis in the Nucleus Accumbens Is Induced by a Single Cocaine Administration and Stabilized by Mitogen-Activated Protein Kinase Interacting Kinase-1 Activity.

Dos Santos M, Salery M, Forget B, Garcia Perez MA, Betuing S, Boudier T, Vanhoutte P, Caboche J, Heck N.

Biol Psychiatry. 2017 Dec 1;82(11):806-818. doi: 10.1016/j.biopsych.2017.03.014. Epub 2017 Mar 29.

40.

Prostaglandin E2 regulates renal function in C57/BL6 mouse with 5/6 nephrectomy.

Jin J, Tang Q, Li Z, Zhao Z, Zhang Z, Lu L, Zhu T, Vanhoutte PM, Leung SW, Tu R, Shi Y.

Life Sci. 2017 Apr 1;174:68-76. doi: 10.1016/j.lfs.2017.03.001. Epub 2017 Mar 2.

PMID:
28263803
41.

12th International Symposium for Mechanisms of Vasodilatation: Celebrating the 30th Anniversary of the Announcement of NO as a Vasodilator Molecule.

Miller VM, Webb RC, Vanhoutte PM.

J Cardiovasc Pharmacol. 2017 May;69(5):245-247. doi: 10.1097/FJC.0000000000000478. No abstract available.

PMID:
28221269
42.

Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice.

Baretella O, Chung SK, Xu A, Vanhoutte PM.

Acta Pharmacol Sin. 2017 Apr;38(4):498-512. doi: 10.1038/aps.2016.138. Epub 2017 Feb 20.

43.

Macro- and microvascular endothelial dysfunction in diabetes.

Shi Y, Vanhoutte PM.

J Diabetes. 2017 May;9(5):434-449. doi: 10.1111/1753-0407.12521. Epub 2017 Mar 1. Review.

PMID:
28044409
44.

An old wheel gets a new CART ….

Vanhoutte PM.

Eur Heart J. 2017 Feb 14;38(7):497-499. doi: 10.1093/eurheartj/ehw508. No abstract available.

PMID:
28039337
45.

Salvage esophagectomy after failure of definitive radiochemotherapy for esophageal cancer.

Farinella E, Safar A, Nasser HA, Bouazza F, Liberale G, Paesmans M, Marechal R, Van Laethem JL, Hendlisz A, VanHoutte P, El Nakadi I.

J Surg Oncol. 2016 Dec;114(7):833-837. doi: 10.1002/jso.24429. Epub 2016 Oct 25.

PMID:
27778349
46.

Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1.

Bai B, Man AW, Yang K, Guo Y, Xu C, Tse HF, Han W, Bloksgaard M, De Mey JG, Vanhoutte PM, Xu A, Wang Y.

Oncotarget. 2016 Jun 28;7(26):39065-39081. doi: 10.18632/oncotarget.9687.

47.

Erratum. APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice. Diabetes 2011;60:3044-3054.

Wang Y, Cheng KK, Lam KS, Wu D, Wang Y, Huang Y, Vanhoutte PM, Sweeney G, Li Y, Xu A.

Diabetes. 2016 Oct;65(10):3219. doi: 10.2337/db16-er10c. No abstract available.

48.

Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway. Diabetes 2010;59:2949-2959.

Chang J, Li Y, Huang Y, Lam KS, Hoo RL, Wong WT, Cheng KK, Wang Y, Vanhoutte PM, Xu A.

Diabetes. 2016 Oct;65(10):3219. doi: 10.2337/db16-er10b. No abstract available.

49.

Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR.

Ling WC, Murugan DD, Lau YS, Vanhoutte PM, Mustafa MR.

Sci Rep. 2016 Sep 12;6:33048. doi: 10.1038/srep33048.

50.

Activity-Regulated Cytoskeleton-Associated Protein Accumulates in the Nucleus in Response to Cocaine and Acts as a Brake on Chromatin Remodeling and Long-Term Behavioral Alterations.

Salery M, Dos Santos M, Saint-Jour E, Moumné L, Pagès C, Kappès V, Parnaudeau S, Caboche J, Vanhoutte P.

Biol Psychiatry. 2017 Apr 1;81(7):573-584. doi: 10.1016/j.biopsych.2016.05.025. Epub 2016 Jun 16.

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