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Items: 9

1.

In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).

Naik PK, Lopus M, Aneja R, Vangapandu SN, Joshi HC.

J Comput Aided Mol Des. 2012 Feb;26(2):233-47. doi: 10.1007/s10822-011-9508-z. Epub 2011 Dec 15.

PMID:
22170255
2.

Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid.

Naik PK, Chatterji BP, Vangapandu SN, Aneja R, Chandra R, Kanteveri S, Joshi HC.

J Comput Aided Mol Des. 2011 May;25(5):443-54. doi: 10.1007/s10822-011-9430-4. Epub 2011 May 5.

PMID:
21544622
3.

Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent.

Aneja R, Liu M, Yates C, Gao J, Dong X, Zhou B, Vangapandu SN, Zhou J, Joshi HC.

Cancer Res. 2008 Mar 1;68(5):1495-503. doi: 10.1158/0008-5472.CAN-07-1874.

4.

Recent patents on proteases and kinases as anti-infective agents: a review.

Vangapandu SN, Aneja R, Chandra R, Joshi HC.

Recent Pat Antiinfect Drug Discov. 2006 Jun;1(2):209-24. Review.

PMID:
18221146
5.

Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog.

Aneja R, Vangapandu SN, Joshi HC.

Bioorg Med Chem. 2006 Dec 15;14(24):8352-8. Epub 2006 Sep 27.

PMID:
17008104
6.

Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.

Aneja R, Vangapandu SN, Lopus M, Viswesarappa VG, Dhiman N, Verma A, Chandra R, Panda D, Joshi HC.

Biochem Pharmacol. 2006 Aug 14;72(4):415-26. Epub 2006 May 10.

PMID:
16780803
7.

Rational design of the microtubule-targeting anti-breast cancer drug EM015.

Aneja R, Lopus M, Zhou J, Vangapandu SN, Ghaleb A, Yao J, Nettles JH, Zhou B, Gupta M, Panda D, Chandra R, Joshi HC.

Cancer Res. 2006 Apr 1;66(7):3782-91.

8.

Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma.

Aneja R, Vangapandu SN, Lopus M, Chandra R, Panda D, Joshi HC.

Mol Pharmacol. 2006 Jun;69(6):1801-9. Epub 2006 Mar 3. Erratum in: Mol Pharmacol. 2007 Aug;72(2):486.

PMID:
16517755
9.

Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.

Aneja R, Zhou J, Vangapandu SN, Zhou B, Chandra R, Joshi HC.

Blood. 2006 Mar 15;107(6):2486-92. Epub 2005 Nov 10.

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