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Items: 14


Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice.

Ballegeer M, Van Looveren K, Timmermans S, Eggermont M, Vandevyver S, Thery F, Dendoncker K, Souffriau J, Vandewalle J, Van Wyngene L, De Rycke R, Takahashi N, Vandenabeele P, Tuckermann J, Reichardt HM, Impens F, Beyaert R, De Bosscher K, Vandenbroucke RE, Libert C.

J Clin Invest. 2018 Jun 25. pii: 96636. doi: 10.1172/JCI96636. [Epub ahead of print]


Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor.

Petta I, Bougarne N, Vandewalle J, Dejager L, Vandevyver S, Ballegeer M, Desmet S, Thommis J, De Cauwer L, Lievens S, Libert C, Tavernier J, De Bosscher K.

Sci Rep. 2017 Aug 21;7(1):8941. doi: 10.1038/s41598-017-09246-6.


Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1.

Puimège L, Van Hauwermeiren F, Steeland S, Van Ryckeghem S, Vandewalle J, Lodens S, Dejager L, Vandevyver S, Staelens J, Timmermans S, Vandenbroucke RE, Libert C.

EMBO Mol Med. 2015 Aug;7(8):1004-17. doi: 10.15252/emmm.201405010.


Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation.

Dejager L, Dendoncker K, Eggermont M, Souffriau J, Van Hauwermeiren F, Willart M, Van Wonterghem E, Naessens T, Ballegeer M, Vandevyver S, Hammad H, Lambrecht B, De Bosscher K, Grooten J, Libert C.

Mucosal Immunol. 2015 Nov;8(6):1212-25. doi: 10.1038/mi.2015.12. Epub 2015 Mar 11.


Comprehensive overview of the structure and regulation of the glucocorticoid receptor.

Vandevyver S, Dejager L, Libert C.

Endocr Rev. 2014 Aug;35(4):671-93. doi: 10.1210/er.2014-1010. Epub 2014 Jun 17. Review.


Dominance of the strongest: inflammatory cytokines versus glucocorticoids.

Dejager L, Vandevyver S, Petta I, Libert C.

Cytokine Growth Factor Rev. 2014 Feb;25(1):21-33. doi: 10.1016/j.cytogfr.2013.12.006. Epub 2013 Dec 24. Review.


An acute phase protein ready to go therapeutic for sepsis.

Vandevyver S, Dejager L, Vandenbroucke RE, Libert C.

EMBO Mol Med. 2014 Jan;6(1):2-3. doi: 10.1002/emmm.201303524. No abstract available.


Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis.

Dejager L, Vandevyver S, Ballegeer M, Van Wonterghem E, An LL, Riggs J, Kolbeck R, Libert C.

J Infect Dis. 2014 Mar;209(6):960-70. doi: 10.1093/infdis/jit600. Epub 2013 Nov 11.


LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome.

Pinheiro I, Dejager L, Petta I, Vandevyver S, Puimège L, Mahieu T, Ballegeer M, Van Hauwermeiren F, Riccardi C, Vuylsteke M, Libert C.

EMBO Mol Med. 2013 Mar;5(3):456-70. doi: 10.1002/emmm.201201683.


New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation.

Vandevyver S, Dejager L, Tuckermann J, Libert C.

Endocrinology. 2013 Mar;154(3):993-1007. doi: 10.1210/en.2012-2045. Epub 2013 Feb 5. Review.


Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.

Vandevyver S, Dejager L, Van Bogaert T, Kleyman A, Liu Y, Tuckermann J, Libert C.

J Clin Invest. 2012 Jun;122(6):2130-40. doi: 10.1172/JCI60006. Epub 2012 May 15.


On the trail of the glucocorticoid receptor: into the nucleus and back.

Vandevyver S, Dejager L, Libert C.

Traffic. 2012 Mar;13(3):364-74. doi: 10.1111/j.1600-0854.2011.01288.x. Epub 2011 Oct 17. Review.


Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock.

Van Bogaert T, Vandevyver S, Dejager L, Van Hauwermeiren F, Pinheiro I, Petta I, Engblom D, Kleyman A, Schütz G, Tuckermann J, Libert C.

J Biol Chem. 2011 Jul 29;286(30):26555-67. doi: 10.1074/jbc.M110.212365. Epub 2011 Jun 6.


Strategies to inhibit the toxicity of systemic TNF treatment.

Van Hauwermeiren F, Puimège L, Vandevyver S, Van Bogaert T, Vanlaere I, Huys L, Dejager L, Libert C.

Adv Exp Med Biol. 2011;691:481-4. doi: 10.1007/978-1-4419-6612-4_49. Review. No abstract available.


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