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Items: 1 to 50 of 282

1.

Testosterone replacement in congenital hypogonadotropic hypogonadism maintains bone density but has only limited osteoanabolic effects.

Antonio L, Caerels S, Jardi F, Delaunay E, Vanderschueren D.

Andrology. 2019 May;7(3):302-306. doi: 10.1111/andr.12604. Epub 2019 Mar 8.

PMID:
30851011
2.

Androgen Receptor in Neurons Slows Age-Related Cortical Thinning in Male Mice.

Jardí F, Kim N, Laurent MR, Khalil R, Deboel L, Schollaert D, van Lenthe GH, Decallonne B, Carmeliet G, Claessens F, Vanderschueren D.

J Bone Miner Res. 2019 Mar;34(3):508-519. doi: 10.1002/jbmr.3625. Epub 2019 Jan 15.

PMID:
30496619
3.

In memoriam: Prof. Dr. Guido Verhoeven 26/03/1945-19/08/2018.

Vanderschueren D, Claessens F.

Andrology. 2018 Nov;6(6):810. doi: 10.1111/andr.12560. Epub 2018 Nov 18. No abstract available.

PMID:
30450788
4.

Long-term complications in patients with chronic hypoparathyroidism: a cross-sectional study.

David K, Moyson C, Vanderschueren D, Decallonne B.

Eur J Endocrinol. 2019 Jan 1;180(1):71-78. doi: 10.1530/EJE-18-0580.

PMID:
30407920
5.

Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women.

Antonio L, Pauwels S, Laurent MR, Vanschoubroeck D, Jans I, Billen J, Claessens F, Decallonne B, De Neubourg D, Vermeersch P, Vanderschueren D.

Int J Endocrinol. 2018 Sep 10;2018:7956951. doi: 10.1155/2018/7956951. eCollection 2018.

6.

Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism: Prospective results from the EMAS.

Rastrelli G, O'Neill TW, Ahern T, Bártfai G, Casanueva FF, Forti G, Keevil B, Giwercman A, Han TS, Slowikowska-Hilczer J, Lean MEJ, Pendleton N, Punab M, Antonio L, Tournoy J, Vanderschueren D, Maggi M, Huhtaniemi IT, Wu FCW; EMAS study group.

Clin Endocrinol (Oxf). 2018 Oct;89(4):459-469. doi: 10.1111/cen.13756. Epub 2018 Jul 23.

PMID:
29855071
7.

Prospective evaluation of hypogonadism in male metastatic renal cell carcinoma patients treated with targeted therapies.

Bastin J, Werbrouck E, Verbiest A, Punie K, Bechter O, Woei-A-Jin FJ, Wolter P, Wildiers H, Lerut E, Dumez H, Decallonne B, Clement P, Vanderschueren D, Albersen M, Oyen R, Schöffski P, Beuselinck B.

Acta Clin Belg. 2019 Jun;74(3):169-179. doi: 10.1080/17843286.2018.1476115. Epub 2018 May 18.

PMID:
29774795
8.

Androgen and estrogen actions on male physical activity: a story beyond muscle.

Jardí F, Laurent MR, Dubois V, Kim N, Khalil R, Decallonne B, Vanderschueren D, Claessens F.

J Endocrinol. 2018 Jul;238(1):R31-R52. doi: 10.1530/JOE-18-0125. Epub 2018 May 9. Review.

PMID:
29743340
9.

Age-related changes in female mouse cortical bone microporosity.

Hemmatian H, Laurent MR, Bakker AD, Vanderschueren D, Klein-Nulend J, van Lenthe GH.

Bone. 2018 Aug;113:1-8. doi: 10.1016/j.bone.2018.05.003. Epub 2018 May 5.

PMID:
29738854
10.

Reassessing Free-Testosterone Calculation by Liquid Chromatography-Tandem Mass Spectrometry Direct Equilibrium Dialysis.

Fiers T, Wu F, Moghetti P, Vanderschueren D, Lapauw B, Kaufman JM.

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2167-2174. doi: 10.1210/jc.2017-02360.

PMID:
29618085
11.

EAA clinical guideline on management of bone health in the andrological outpatient clinic.

Rochira V, Antonio L, Vanderschueren D.

Andrology. 2018 Mar;6(2):272-285. doi: 10.1111/andr.12470. Epub 2018 Mar 2. Review.

12.

Hypocalcemia after Denosumab in a Pulmonary Hypertension Patient Receiving Epoprostenol.

De Muynck B, Leys M, Cuypers J, Vanderschueren D, Delcroix M, Belge C.

Respiration. 2018;95(2):139-142. doi: 10.1159/000481713. Epub 2017 Oct 30.

13.

Testosterone boosts physical activity in male mice via dopaminergic pathways.

Jardí F, Laurent MR, Kim N, Khalil R, De Bundel D, Van Eeckhaut A, Van Helleputte L, Deboel L, Dubois V, Schollaert D, Decallonne B, Carmeliet G, Van den Bosch L, D'Hooge R, Claessens F, Vanderschueren D.

Sci Rep. 2018 Jan 17;8(1):957. doi: 10.1038/s41598-017-19104-0.

14.

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C.

J Clin Endocrinol Metab. 2018 Mar 1;103(3):991-1004. doi: 10.1210/jc.2017-02060. Erratum in: J Clin Endocrinol Metab. 2019 Jul 1;104(7):2580.

15.

Reproductive Hormone Levels Predict Changes in Frailty Status in Community-Dwelling Older Men: European Male Ageing Study Prospective Data.

Swiecicka A, Eendebak RJAH, Lunt M, O'Neill TW, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Slowikowska-Hilczer J, Lean MEJ, Pendleton N, Punab M, Vanderschueren D, Huhtaniemi IT, Wu FCW, Rutter MK; European Male Ageing Study Group.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):701-709. doi: 10.1210/jc.2017-01172.

16.

Elevated luteinizing hormone despite normal testosterone levels in older men-natural history, risk factors and clinical features.

Eendebak RJAH, Ahern T, Swiecicka A, Pye SR, O'Neill TW, Bartfai G, Casanueva FF, Maggi M, Forti G, Giwercman A, Han TS, Słowikowska-Hilczer J, Lean MEJ, Punab M, Pendleton N, Keevil BG, Vanderschueren D, Rutter MK, Tampubolon G, Goodacre R, Huhtaniemi IT, Wu FCW; EMAS Group.

Clin Endocrinol (Oxf). 2018 Mar;88(3):479-490. doi: 10.1111/cen.13524. Epub 2017 Dec 25.

PMID:
29178359
17.

Estradiol and Age-Related Bone Loss in Men.

Jardí F, Laurent MR, Claessens F, Vanderschueren D.

Physiol Rev. 2018 Jan 1;98(1):1. doi: 10.1152/physrev.00051.2017. No abstract available.

18.

Sex steroids and the kidney: role in renal calcium and phosphate handling.

Khalil R, Kim NR, Jardi F, Vanderschueren D, Claessens F, Decallonne B.

Mol Cell Endocrinol. 2018 Apr 15;465:61-72. doi: 10.1016/j.mce.2017.11.011. Epub 2017 Nov 16. Review.

PMID:
29155307
19.

Vitamin D supplementation in cutaneous malignant melanoma outcome (ViDMe): a randomized controlled trial.

De Smedt J, Van Kelst S, Boecxstaens V, Stas M, Bogaerts K, Vanderschueren D, Aura C, Vandenberghe K, Lambrechts D, Wolter P, Bechter O, Nikkels A, Strobbe T, Emri G, Marasigan V, Garmyn M.

BMC Cancer. 2017 Aug 23;17(1):562. doi: 10.1186/s12885-017-3538-4.

20.

Accuracy and reproducibility of mouse cortical bone microporosity as quantified by desktop microcomputed tomography.

Hemmatian H, Laurent MR, Ghazanfari S, Vanderschueren D, Bakker AD, Klein-Nulend J, van Lenthe GH.

PLoS One. 2017 Aug 10;12(8):e0182996. doi: 10.1371/journal.pone.0182996. eCollection 2017.

21.

Nonandrogenic Anabolic Hormones Predict Risk of Frailty: European Male Ageing Study Prospective Data.

Swiecicka A, Lunt M, Ahern T, O'Neill TW, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Lean MEJ, Pendleton N, Punab M, Slowikowska-Hilczer J, Vanderschueren D, Huhtaniemi IT, Wu FCW, Rutter MK; EMAS Study Group.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2798-2806. doi: 10.1210/jc.2017-00090.

22.

A shortened tamoxifen induction scheme to induce CreER recombinase without side effects on the male mouse skeleton.

Jardí F, Laurent MR, Dubois V, Khalil R, Deboel L, Schollaert D, Van Den Bosch L, Decallonne B, Carmeliet G, Claessens F, Vanderschueren D.

Mol Cell Endocrinol. 2017 Sep 5;452:57-63. doi: 10.1016/j.mce.2017.05.012. Epub 2017 May 11.

PMID:
28504114
23.

Glycemia but not the Metabolic Syndrome is Associated with Cognitive Decline: Findings from the European Male Ageing Study.

Overman MJ, Pendleton N, O'Neill TW, Bartfai G, Casanueva FF, Forti G, Rastrelli G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean MEJ, Punab M, Lee DM, Correa ES, Ahern T, Laurent MR, Verschueren SMP, Antonio L, Gielen E, Rutter MK, Vanderschueren D, Wu FCW, Tournoy J; EMAS study group.

Am J Geriatr Psychiatry. 2017 Jun;25(6):662-671. doi: 10.1016/j.jagp.2017.02.004. Epub 2017 Feb 7.

PMID:
28259698
24.

1β,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum.

Pauwels S, Jans I, Billen J, Heijboer A, Verstuyf A, Carmeliet G, Mathieu C, Maestro M, Waelkens E, Evenepoel P, Bouillon R, Vanderschueren D, Vermeersch P.

J Steroid Biochem Mol Biol. 2017 Oct;173:341-348. doi: 10.1016/j.jsbmb.2017.02.004. Epub 2017 Feb 11.

PMID:
28193495
25.

Hypervitaminosis D Associated With Tanning Bed Use: A Case Report.

Laurent MR, Gielen E, Pauwels S, Vanderschueren D, Bouillon R.

Ann Intern Med. 2017 Jan 17;166(2):155-156. doi: 10.7326/L16-0138. No abstract available.

PMID:
28114469
26.

Frailty and bone health in European men.

Cook MJ, Oldroyd A, Pye SR, Ward KA, Gielen E, Ravindrarajah R, Adams JE, Lee DM, Bartfai G, Boonen S, Casanueva F, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Pendleton N, Punab M, Vanderschueren D, Wu FC, O'Neill TW; EMAS Study Group.

Age Ageing. 2017 Jul 1;46(4):635-641. doi: 10.1093/ageing/afw205.

27.

Bone turnover predicts change in volumetric bone density and bone geometry at the radius in men.

Pye SR, Ward KA, Cook MJ, Laurent MR, Gielen E, Borghs H, Adams JE, Boonen S, Vanderschueren D, Wu FC, O'Neill TW.

Osteoporos Int. 2017 Mar;28(3):935-944. doi: 10.1007/s00198-016-3816-z. Epub 2016 Nov 4.

28.

Estrogens and Androgens in Skeletal Physiology and Pathophysiology.

Almeida M, Laurent MR, Dubois V, Claessens F, O'Brien CA, Bouillon R, Vanderschueren D, Manolagas SC.

Physiol Rev. 2017 Jan;97(1):135-187. Review.

29.

Androgens have antiresorptive effects on trabecular disuse osteopenia independent from muscle atrophy.

Laurent MR, Jardí F, Dubois V, Schollaert D, Khalil R, Gielen E, Carmeliet G, Claessens F, Vanderschueren D.

Bone. 2016 Dec;93:33-42. doi: 10.1016/j.bone.2016.09.011. Epub 2016 Sep 10.

PMID:
27622887
30.

Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis.

Laurent MR, Hammond GL, Blokland M, Jardí F, Antonio L, Dubois V, Khalil R, Sterk SS, Gielen E, Decallonne B, Carmeliet G, Kaufman JM, Fiers T, Huhtaniemi IT, Vanderschueren D, Claessens F.

Sci Rep. 2016 Oct 17;6:35539. doi: 10.1038/srep35539.

31.

Changes in prevalence of obesity and high waist circumference over four years across European regions: the European male ageing study (EMAS).

Han TS, Correa E, Lean ME, Lee DM, O'Neill TW, Bartfai G, Forti G, Giwercman A, Kula K, Pendleton N, Punab M, Rutter MK, Vanderschueren D, Huhtaniemi IT, Wu FC, Casanueva FF; and the EMAS Study Group.

Endocrine. 2017 Feb;55(2):456-469. doi: 10.1007/s12020-016-1135-y. Epub 2016 Oct 13.

32.

The androgen receptor gene CAG repeat 
in relation to 4-year changes in 
androgen-sensitive endpoints in 
community-dwelling older European men.

Eendebak RJ, Huhtaniemi IT, Pye SR, Ahern T, O'Neill TW, Bartfai G, Casanueva FF, Maggi M, Forti G, Alston RD, Giwercman A, Han TS, Kula K, Lean ME, Punab M, Pendleton N, Keevil BG, Vanderschueren D, Rutter MK, Tampubolon G, Goodacre R, Wu FC; EMAS Group.

Eur J Endocrinol. 2016 Dec;175(6):583-593. Epub 2016 Sep 15.

PMID:
27634944
33.

Effects of sex hormone-binding globulin (SHBG) on androgen bioactivity in vitro.

Laurent MR, Helsen C, Antonio L, Schollaert D, Joniau S, Vos MJ, Decallonne B, Hammond GL, Vanderschueren D, Claessens F.

Mol Cell Endocrinol. 2016 Dec 5;437:280-291. doi: 10.1016/j.mce.2016.08.041. Epub 2016 Aug 26.

PMID:
27576188
34.

Testosterone Treatment in Older Men.

Laurent MR, Antonio L, Vanderschueren D.

N Engl J Med. 2016 Jul 7;375(1):89-90. doi: 10.1056/NEJMc1603665. No abstract available.

PMID:
27406358
35.

Natural history, risk factors and clinical features of primary hypogonadism in ageing men: Longitudinal Data from the European Male Ageing Study.

Ahern T, Swiecicka A, Eendebak RJ, Carter EL, Finn JD, Pye SR, O'Neill TW, Antonio L, Keevil B, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Lean ME, Pendleton N, Punab M, Rastrelli G, Rutter MK, Vanderschueren D, Huhtaniemi IT, Wu FC; EMAS study group.

Clin Endocrinol (Oxf). 2016 Dec;85(6):891-901. doi: 10.1111/cen.13152. Epub 2016 Aug 18.

PMID:
27374987
36.

Evaluation of cognitive subdomains, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D in the European Male Ageing Study.

Overman MJ, Pendleton N, O'Neill TW, Bartfai G, Casanueva FF, Finn JD, Forti G, Rastrelli G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean MEJ, Punab M, Lee DM, Correa ES, Ahern T, Verschueren SMP, Antonio L, Gielen E, Rutter MK, Vanderschueren D, Wu FCW, Tournoy J; EMAS Study Group.

Eur J Nutr. 2017 Sep;56(6):2093-2103. doi: 10.1007/s00394-016-1247-4. Epub 2016 Jul 1.

PMID:
27370643
37.

Bone disorders: Mechanisms and targets.

Vanderschueren D, Laurent MR, Carmeliet G.

Mol Cell Endocrinol. 2016 Sep 5;432:1-2. doi: 10.1016/j.mce.2016.06.001. No abstract available.

PMID:
27288843
38.

Lower bone turnover and relative bone deficits in men with metabolic syndrome: a matter of insulin sensitivity? The European Male Ageing Study.

Laurent MR, Cook MJ, Gielen E, Ward KA, Antonio L, Adams JE, Decallonne B, Bartfai G, Casanueva FF, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Lean MEJ, Lee DM, Pendleton N, Punab M, Claessens F, Wu FCW, Vanderschueren D, Pye SR, O'Neill TW; EMAS Group.

Osteoporos Int. 2016 Nov;27(11):3227-3237. doi: 10.1007/s00198-016-3656-x. Epub 2016 Jun 7.

PMID:
27273111
39.

Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations.

Nielson CM, Jones KS, Bouillon R; Osteoporotic Fractures in Men (MrOS) Research Group, Chun RF, Jacobs J, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Zmuda JM, Lapidus J, Cauley JA, Schoenmakers I, Orwoll ES.

N Engl J Med. 2016 Apr 28;374(17):1695-6. doi: 10.1056/NEJMc1513502. Epub 2016 Mar 23. No abstract available.

40.

Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations.

Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Schepmoes AA, Zmuda JM, Lapidus J, Cauley JA, Bouillon R, Schoenmakers I, Orwoll ES; Osteoporotic Fractures in Men (MrOS) Research Group.

J Clin Endocrinol Metab. 2016 May;101(5):2226-34. doi: 10.1210/jc.2016-1104. Epub 2016 Mar 23.

41.

Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.

Antonio L, Wu FC, O'Neill TW, Pye SR, Ahern TB, Laurent MR, Huhtaniemi IT, Lean ME, Keevil BG, Rastrelli G, Forti G, Bartfai G, Casanueva FF, Kula K, Punab M, Giwercman A, Claessens F, Decallonne B, Vanderschueren D; European Male Ageing Study Study Group.

J Clin Endocrinol Metab. 2016 Jul;101(7):2647-57. doi: 10.1210/jc.2015-4106. Epub 2016 Feb 24.

PMID:
26909800
42.

Phosphorus metabolism in peritoneal dialysis- and haemodialysis-treated patients.

Evenepoel P, Meijers BK, Bammens B, Viaene L, Claes K, Sprangers B, Naesens M, Hoekstra T, Schlieper G, Vanderschueren D, Kuypers D.

Nephrol Dial Transplant. 2016 Sep;31(9):1508-14. doi: 10.1093/ndt/gfv414. Epub 2016 Jan 31.

PMID:
26908778
43.

Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men.

Srikanth P, Chun RF, Hewison M, Adams JS, Bouillon R, Vanderschueren D, Lane N, Cawthon PM, Dam T, Barrett-Connor E, Daniels LB, Shikany JM, Stefanick ML, Cauley JA, Orwoll ES, Nielson CM; Osteoporotic Fractures in Men (MrOS) Study Research Group.

Osteoporos Int. 2016 Jul;27(7):2291-2300. doi: 10.1007/s00198-016-3537-3. Epub 2016 Feb 23.

44.

Genetic variant in the osteoprotegerin gene is associated with aromatase inhibitor-related musculoskeletal toxicity in breast cancer patients.

Lintermans A, Van Asten K, Jongen L, Van Brussel T, Laenen A, Verhaeghe J, Vanderschueren D, Lambrechts D, Neven P.

Eur J Cancer. 2016 Mar;56:31-36. doi: 10.1016/j.ejca.2015.12.013. Epub 2016 Jan 19.

PMID:
26798969
45.

Low vitamin D and the risk of developing chronic widespread pain: results from the European male ageing study.

McCabe PS, Pye SR, Beth JM, Lee DM, Tajar A, Bartfai G, Boonen S, Bouillon R, Casanueva F, Finn JD, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Pendleton N, Punab M, Vanderschueren D, Wu FC, O'Neill TW; EMAS Study Group.

BMC Musculoskelet Disord. 2016 Jan 16;17:32. doi: 10.1186/s12891-016-0881-6.

46.

Determination of human reference values for serum total 1,25-dihydroxyvitamin D using an extensively validated 2D ID-UPLC-MS/MS method.

Dirks NF, Martens F, Vanderschueren D, Billen J, Pauwels S, Ackermans MT, Endert E, Heijer MD, Blankenstein MA, Heijboer AC.

J Steroid Biochem Mol Biol. 2016 Nov;164:127-133. doi: 10.1016/j.jsbmb.2015.12.003. Epub 2015 Dec 10.

PMID:
26690787
47.

Chronic widespread pain is associated with worsening frailty in European men.

Wade KF, Lee DM, McBeth J, Ravindrarajah R, Gielen E, Pye SR, Vanderschueren D, Pendleton N, Finn JD, Bartfai G, Casanueva FF, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Punab M, Wu FC, O'Neill TW.

Age Ageing. 2016 Mar;45(2):268-74. doi: 10.1093/ageing/afv170. Epub 2015 Dec 17.

48.

Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male Mice.

Dubois V, Laurent MR, Jardi F, Antonio L, Lemaire K, Goyvaerts L, Deldicque L, Carmeliet G, Decallonne B, Vanderschueren D, Claessens F.

Endocrinology. 2016 Feb;157(2):648-65. doi: 10.1210/en.2015-1713. Epub 2015 Nov 12.

PMID:
26562264
49.

Muscle-bone interactions: From experimental models to the clinic? A critical update.

Laurent MR, Dubois V, Claessens F, Verschueren SM, Vanderschueren D, Gielen E, Jardí F.

Mol Cell Endocrinol. 2016 Sep 5;432:14-36. doi: 10.1016/j.mce.2015.10.017. Epub 2015 Oct 23. Review.

PMID:
26506009
50.

Endocrine determinants of incident sarcopenia in middle-aged and elderly European men.

Gielen E, O'Neill TW, Pye SR, Adams JE, Wu FC, Laurent MR, Claessens F, Ward KA, Boonen S, Bouillon R, Vanderschueren D, Verschueren S.

J Cachexia Sarcopenia Muscle. 2015 Sep;6(3):242-52. doi: 10.1002/jcsm.12030. Epub 2015 Apr 27.

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