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Items: 15


A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.

Seeherman HJ, Berasi SP, Brown CT, Martinez RX, Juo ZS, Jelinsky S, Cain MJ, Grode J, Tumelty KE, Bohner M, Grinberg O, Orr N, Shoseyov O, Eyckmans J, Chen C, Morales PR, Wilson CG, Vanderploeg EJ, Wozney JM.

Sci Transl Med. 2019 Apr 24;11(489). pii: eaar4953. doi: 10.1126/scitranslmed.aar4953.


Sustained delivery of bioactive TGF-β1 from self-assembling peptide hydrogels induces chondrogenesis of encapsulated bone marrow stromal cells.

Kopesky PW, Byun S, Vanderploeg EJ, Kisiday JD, Frisbie DD, Grodzinsky AJ.

J Biomed Mater Res A. 2014 May;102(5):1275-85. doi: 10.1002/jbm.a.34789. Epub 2013 Jun 4.


Regional variations in the distribution and colocalization of extracellular matrix proteins in the juvenile bovine meniscus.

Vanderploeg EJ, Wilson CG, Imler SM, Ling CH, Levenston ME.

J Anat. 2012 Aug;221(2):174-86. doi: 10.1111/j.1469-7580.2012.01523.x. Epub 2012 Jun 18.


Effect of self-assembling peptide, chondrogenic factors, and bone marrow-derived stromal cells on osteochondral repair.

Miller RE, Grodzinsky AJ, Vanderploeg EJ, Lee C, Ferris DJ, Barrett MF, Kisiday JD, Frisbie DD.

Osteoarthritis Cartilage. 2010 Dec;18(12):1608-19. doi: 10.1016/j.joca.2010.09.004. Epub 2010 Sep 17.


Controlled delivery of transforming growth factor β1 by self-assembling peptide hydrogels induces chondrogenesis of bone marrow stromal cells and modulates Smad2/3 signaling.

Kopesky PW, Vanderploeg EJ, Kisiday JD, Frisbie DD, Sandy JD, Grodzinsky AJ.

Tissue Eng Part A. 2011 Jan;17(1-2):83-92. doi: 10.1089/ten.TEA.2010.0198. Epub 2010 Sep 22.


Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes.

Kopesky PW, Lee HY, Vanderploeg EJ, Kisiday JD, Frisbie DD, Plaas AH, Ortiz C, Grodzinsky AJ.

Matrix Biol. 2010 Jun;29(5):427-38. doi: 10.1016/j.matbio.2010.02.003. Epub 2010 Feb 12.


Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs.

Connelly JT, Vanderploeg EJ, Mouw JK, Wilson CG, Levenston ME.

Tissue Eng Part A. 2010 Jun;16(6):1913-23. doi: 10.1089/ten.TEA.2009.0561.


Mechanical injury of explants from the articulating surface of the inner meniscus.

Kisiday JD, Vanderploeg EJ, McIlwraith CW, Grodzinsky AJ, Frisbie DD.

Arch Biochem Biophys. 2010 Feb 15;494(2):138-44. doi: 10.1016/ Epub 2009 Nov 26.


Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications.

Wilson CG, Vanderploeg EJ, Zuo F, Sandy JD, Levenston ME.

Arthritis Res Ther. 2009;11(6):R173. doi: 10.1186/ar2862. Epub 2009 Nov 17.


Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage.

Sui Y, Lee JH, DiMicco MA, Vanderploeg EJ, Blake SM, Hung HH, Plaas AH, James IE, Song XY, Lark MW, Grodzinsky AJ.

Arthritis Rheum. 2009 Oct;60(10):2985-96. doi: 10.1002/art.24857.


Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells.

Kopesky PW, Vanderploeg EJ, Sandy JS, Kurz B, Grodzinsky AJ.

Tissue Eng Part A. 2010 Feb;16(2):465-77. doi: 10.1089/ten.TEA.2009.0158.


Can the meniscus affect the nature of a chondrocyte?

Vanderploeg EJ, Grodzinsky AJ.

Osteoarthritis Cartilage. 2009 Aug;17(8):969-70. doi: 10.1016/j.joca.2009.05.007. Epub 2009 May 19. No abstract available.


Articular chondrocytes derived from distinct tissue zones differentially respond to in vitro oscillatory tensile loading.

Vanderploeg EJ, Wilson CG, Levenston ME.

Osteoarthritis Cartilage. 2008 Oct;16(10):1228-36. doi: 10.1016/j.joca.2008.02.016. Epub 2008 Apr 8.


Oscillatory tension differentially modulates matrix metabolism and cytoskeletal organization in chondrocytes and fibrochondrocytes.

Vanderploeg EJ, Imler SM, Brodkin KR, García AJ, Levenston ME.

J Biomech. 2004 Dec;37(12):1941-52.


The influence of cyclic tension amplitude on chondrocyte matrix synthesis: experimental and finite element analyses.

Connelly JT, Vanderploeg EJ, Levenston ME.

Biorheology. 2004;41(3-4):377-87.


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