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Items: 1 to 50 of 89

1.

A lipid-mediated conformational switch modulates the thermosensing activity of DesK.

Inda ME, Vandenbranden M, Fernández A, de Mendoza D, Ruysschaert JM, Cybulski LE.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3579-84. doi: 10.1073/pnas.1317147111. Epub 2014 Feb 12.

2.

Cationic lipid nanocarriers activate Toll-like receptor 2 and NLRP3 inflammasome pathways.

Lonez C, Bessodes M, Scherman D, Vandenbranden M, Escriou V, Ruysschaert JM.

Nanomedicine. 2014 May;10(4):775-82. doi: 10.1016/j.nano.2013.12.003. Epub 2013 Dec 20.

PMID:
24361386
3.

Identification of peptides derived from the human antimicrobial peptide LL-37 active against biofilms formed by Pseudomonas aeruginosa using a library of truncated fragments.

Nagant C, Pitts B, Nazmi K, Vandenbranden M, Bolscher JG, Stewart PS, Dehaye JP.

Antimicrob Agents Chemother. 2012 Nov;56(11):5698-708. doi: 10.1128/AAC.00918-12. Epub 2012 Aug 20.

4.

Cationic lipids activate intracellular signaling pathways.

Lonez C, Vandenbranden M, Ruysschaert JM.

Adv Drug Deliv Rev. 2012 Dec;64(15):1749-58. doi: 10.1016/j.addr.2012.05.009. Epub 2012 May 23. Review.

PMID:
22634161
5.

Temperature-dependence of cationic lipid bilayer intermixing: possible role of interdigitation.

Oliveira TR, Duarte EL, Lamy MT, Vandenbranden M, Ruysschaert JM, Lonez C.

Langmuir. 2012 Mar 13;28(10):4640-7. doi: 10.1021/la3001569. Epub 2012 Feb 28.

PMID:
22332736
6.

The cationic lipid, diC14 amidine, extends the adjuvant properties of aluminum salts through a TLR-4- and caspase-1-independent mechanism.

Wilmar A, Lonez C, Vermeersch M, Andrianne M, Pérez-Morga D, Ruysschaert JM, Vandenbranden M, Leo O, Temmerman ST.

Vaccine. 2012 Jan 5;30(2):414-24. doi: 10.1016/j.vaccine.2011.10.071. Epub 2011 Nov 7.

PMID:
22075093
7.

Fusogenic activity of cationic lipids and lipid shape distribution.

Lonez C, Lensink MF, Kleiren E, Vanderwinden JM, Ruysschaert JM, Vandenbranden M.

Cell Mol Life Sci. 2010 Feb;67(3):483-94. doi: 10.1007/s00018-009-0197-x. Epub 2009 Nov 19.

PMID:
19924382
8.

Regulation by CRAMP of the responses of murine peritoneal macrophages to extracellular ATP.

Seil M, Kabré E, Nagant C, Vandenbranden M, Fontanils U, Marino A, Pochet S, Dehaye JP.

Biochim Biophys Acta. 2010 Mar;1798(3):569-78. doi: 10.1016/j.bbamem.2009.11.002. Epub 2009 Nov 11.

9.

Cationic lipids activate cellular cascades. Which receptors are involved?

Lonez C, Lensink MF, Vandenbranden M, Ruysschaert JM.

Biochim Biophys Acta. 2009 Jun;1790(6):425-30. doi: 10.1016/j.bbagen.2009.02.015. Epub 2009 Mar 6. Review.

PMID:
19269309
10.

Characterization of the cationic DiC(14)-amidine bilayer by mixed DMPC/DiC(14)-amidine molecular dynamics simulations shows an interdigitated nonlamellar bilayer phase.

Lensink MF, Lonez C, Ruysschaert JM, Vandenbranden M.

Langmuir. 2009 May 5;25(9):5230-8. doi: 10.1021/la804150p.

PMID:
19231818
11.

A hypoallergenic variant of Der p 1 as a candidate for mite allergy vaccines.

Walgraffe D, Mattéotti C, El Bakkoury M, Garcia L, Marchand C, Bullens D, Vandenbranden M, Jacquet A.

J Allergy Clin Immunol. 2009 May;123(5):1150-6. doi: 10.1016/j.jaci.2008.11.038. Epub 2009 Jan 18.

PMID:
19152967
12.

Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation.

Dumez ME, Teller N, Mercier F, Tanaka T, Vandenberghe I, Vandenbranden M, Devreese B, Luxen A, Frère JM, Matagne A, Jacquet A, Galleni M, Chevigné A.

J Biol Chem. 2008 Nov 7;283(45):30606-17. doi: 10.1074/jbc.M803041200. Epub 2008 Aug 25.

13.

Vitamin E transfer from lipid emulsions to plasma lipoproteins: mediation by multiple mechanisms.

Hacquebard M, Vandenbranden M, Malaisse WJ, Ruysschaert JM, Deckelbaum RJ, Carpentier YA.

Lipids. 2008 Jul;43(7):663-71. doi: 10.1007/s11745-008-3184-3. Epub 2008 May 29.

PMID:
18509690
14.

Cationic liposomal lipids: from gene carriers to cell signaling.

Lonez C, Vandenbranden M, Ruysschaert JM.

Prog Lipid Res. 2008 Sep;47(5):340-7. doi: 10.1016/j.plipres.2008.03.002. Epub 2008 Apr 1. Review.

PMID:
18424270
15.

Cationic lipid/DNA complexes induce TNF-alpha secretion in splenic macrophages.

Lonez C, Vandenbranden M, Elouahabi A, Ruysschaert JM.

Eur J Pharm Biopharm. 2008 Aug;69(3):817-23. doi: 10.1016/j.ejpb.2008.01.035. Epub 2008 Feb 9.

PMID:
18407478
16.

DiC14-amidine cationic liposomes stimulate myeloid dendritic cells through Toll-like receptor 4.

Tanaka T, Legat A, Adam E, Steuve J, Gatot JS, Vandenbranden M, Ulianov L, Lonez C, Ruysschaert JM, Muraille E, Tuynder M, Goldman M, Jacquet A.

Eur J Immunol. 2008 May;38(5):1351-7. doi: 10.1002/eji.200737998.

17.

DiC14-amidine confers new anti-inflammatory properties to phospholipids.

Lonez C, Legat A, Vandenbranden M, Ruysschaert JM.

Cell Mol Life Sci. 2008 Feb;65(4):620-30.

PMID:
18097635
18.

Sequence-optimised E2 constructs from BVDV-1b and BVDV-2 for DNA immunisation in cattle.

Couvreur B, Letellier C, Olivier F, Dehan P, Elouahabi A, Vandenbranden M, Ruysschaert JM, Hamers C, Pastoret PP, Kerkhofs P.

Vet Res. 2007 Nov-Dec;38(6):819-34. Epub 2007 Aug 31.

19.

Cationic lipids involved in gene transfer mobilize intracellular calcium.

Ouali M, Ruysschaert JM, Lonez C, Vandenbranden M.

Mol Membr Biol. 2007 May-Jun;24(3):225-32.

PMID:
17520479
20.

Free diC14-amidine liposomes inhibit the TNF-alpha secretion induced by CpG sequences and lipopolysaccharides: role of lipoproteins.

Lonez C, Vandenbranden M, Ouali M, Legat A, Ruysschaert JM, Elouahabi A.

Mol Membr Biol. 2006 May-Jun;23(3):227-34.

PMID:
16785206
21.

Modulation by LL-37 of the responses of salivary glands to purinergic agonists.

Pochet S, Tandel S, Querriére S, Tre-Hardy M, Garcia-Marcos M, De Lorenzi M, Vandenbranden M, Marino A, Devleeschouwer M, Dehaye JP.

Mol Pharmacol. 2006 Jun;69(6):2037-46. Epub 2006 Mar 2.

PMID:
16514052
22.

Vaccination with the recombinant allergen ProDer p 1 complexed with the cationic lipid DiC14-amidine prevents allergic responses to house dust mite.

Jacquet A, Vanderschrick JF, Vandenbranden M, Elouahabi A, Magi M, Garcia L, Ruysschaert JM.

Mol Ther. 2005 Jun;11(6):960-8.

23.

Lipid mixing between lipoplexes and plasma lipoproteins is a major barrier for intravenous transfection mediated by cationic lipids.

Tandia BM, Lonez C, Vandenbranden M, Ruysschaert JM, Elouahabi A.

J Biol Chem. 2005 Apr 1;280(13):12255-61. Epub 2005 Jan 20.

24.

Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo.

Ring BJ, Patterson BE, Mitchell MI, Vandenbranden M, Gillespie J, Bedding AW, Jewell H, Payne CD, Forgue ST, Eckstein J, Wrighton SA, Phillips DL.

Clin Pharmacol Ther. 2005 Jan;77(1):63-75.

PMID:
15637532
25.

Mistargeted MRPdeltaF728 mutant is rescued by intracellular GSH.

Buyse F, Vandenbranden M, Ruysschaert JM.

FEBS Lett. 2004 Dec 3;578(1-2):145-51.

26.

Heat denaturation affects the ProDer p 1 IgE reactivity and downregulates the development of the specific allergic response.

Magi M, Garcia L, Vandenbranden M, Palmantier R, Jacquet A.

J Allergy Clin Immunol. 2004 Sep;114(3):545-52.

PMID:
15356555
27.

Calorimetry of cationic liposome-DNA complex and intracellular visualization of the complexes.

Elouahabi A, Thiry M, Pector V, Ruysschaert JM, Vandenbranden M.

Methods Enzymol. 2003;373:313-32. No abstract available.

PMID:
14714412
28.

Atomoxetine hydrochloride: clinical drug-drug interaction prediction and outcome.

Sauer JM, Long AJ, Ring B, Gillespie JS, Sanburn NP, DeSante KA, Petullo D, VandenBranden MR, Jensen CB, Wrighton SA, Smith BP, Read HA, Witcher JW.

J Pharmacol Exp Ther. 2004 Feb;308(2):410-8. Epub 2003 Nov 10.

PMID:
14610241
29.
30.

Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridoma.

Van Laethem F, Liang X, Andris F, Urbain J, Vandenbranden M, Ruysschaert JM, Resh MD, Stulnig TM, Leo O.

J Immunol. 2003 Mar 15;170(6):2932-9.

31.

Free cationic liposomes inhibit the inflammatory response to cationic lipid-DNA complex injected intravenously and enhance its transfection efficiency.

Elouahabi A, Flamand V, Ozkan S, Paulart F, Vandenbranden M, Goldman M, Ruysschaert JM.

Mol Ther. 2003 Jan;7(1):81-8.

32.

Biophysical and transfection studies of the diC(14)-amidine/DNA complex.

Cherezov V, Qiu H, Pector V, Vandenbranden M, Ruysschaert JM, Caffrey M.

Biophys J. 2002 Jun;82(6):3105-17.

33.

Role of intracellular cationic liposome-DNA complex dissociation in transfection mediated by cationic lipids.

Cornelis S, Vandenbranden M, Ruysschaert JM, Elouahabi A.

DNA Cell Biol. 2002 Feb;21(2):91-7.

PMID:
11953008
34.

Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine.

Ring BJ, Eckstein JA, Gillespie JS, Binkley SN, VandenBranden M, Wrighton SA.

J Pharmacol Exp Ther. 2001 Jun;297(3):1044-50.

PMID:
11356927
35.

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank.

Fisher MB, Vandenbranden M, Findlay K, Burchell B, Thummel KE, Hall SD, Wrighton SA.

Pharmacogenetics. 2000 Nov;10(8):727-39.

PMID:
11186135
36.

Biophysical and structural properties of DNA.diC(14)-amidine complexes. Influence of the DNA/lipid ratio.

Pector V, Backmann J, Maes D, Vandenbranden M, Ruysschaert JM.

J Biol Chem. 2000 Sep 22;275(38):29533-8.

37.

In vitro glucuronidation using human liver microsomes and the pore-forming peptide alamethicin.

Fisher MB, Campanale K, Ackermann BL, VandenBranden M, Wrighton SA.

Drug Metab Dispos. 2000 May;28(5):560-6.

PMID:
10772635
38.

Occurrence of an HIV-1 gp160 endoproteolytic activity in low-density vesicles and evidence for a distinct density distribution from endogenously expressed furin and PC7/LPC convertases.

Wouters S, Decroly E, Vandenbranden M, Shober D, Fuchs R, Morel V, Leruth M, Seidah NG, Courtoy PJ, Ruysschaert JM.

FEBS Lett. 1999 Jul 30;456(1):97-102.

39.

Intracellular visualization of BrdU-labeled plasmid DNA/cationic liposome complexes.

El Ouahabi A, Thiry M, Schiffmann S, Fuks R, Nguyen-Tran H, Ruysschaert JM, Vandenbranden M.

J Histochem Cytochem. 1999 Sep;47(9):1159-66.

PMID:
10449537
40.

Three-dimensional quantitative structure activity relationship analyses of substrates for CYP2B6.

Ekins S, Bravi G, Ring BJ, Gillespie TA, Gillespie JS, Vandenbranden M, Wrighton SA, Wikel JH.

J Pharmacol Exp Ther. 1999 Jan;288(1):21-9.

PMID:
9862748
41.

Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments.

Wouters S, Leruth M, Decroly E, Vandenbranden M, Creemers JW, van de Loo JW, Ruysschaert JM, Courtoy PJ.

Biochem J. 1998 Dec 1;336 ( Pt 2):311-6.

42.

Alterations of the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices.

VandenBranden M, Wrighton SA, Ekins S, Gillespie JS, Binkley SN, Ring BJ, Gadberry MG, Mullins DC, Strom SC, Jensen CB.

Drug Metab Dispos. 1998 Nov;26(11):1063-8.

PMID:
9806947
43.

Further characterization of the expression in liver and catalytic activity of CYP2B6.

Ekins S, Vandenbranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV, Wrighton SA.

J Pharmacol Exp Ther. 1998 Sep;286(3):1253-9.

PMID:
9732386
44.

Physico-chemical characterization of a double long-chain cationic amphiphile (Vectamidine) by microelectrophoresis.

Pector V, Caspers J, Banerjee S, Deriemaeker L, Fuks R, El Ouahabi A, Vandenbranden M, Finsy R, Ruysschaert JM.

Biochim Biophys Acta. 1998 Jul 17;1372(2):339-46.

45.

Liver dihydropyrimidine dehydrogenase activity in human, cynomolgus monkey, rhesus monkey, dog, rat and mouse.

Sludden J, Hardy SC, VandenBranden MR, Wrighton SA, McLeod HL.

Pharmacology. 1998 May;56(5):276-80.

PMID:
9597696
46.
47.

Human immunodeficiency virus type-1-specific immune responses induced by DNA vaccination are greatly enhanced by mannan-coated diC14-amidine.

Sasaki S, Fukushima J, Arai H, Kusakabe KI, Hamajima K, Ishii N, Hirahara F, Okuda K, Kawamoto S, Ruysschaert JM, Vandenbranden M, Wahren B, Okuda K.

Eur J Immunol. 1997 Dec;27(12):3121-9.

PMID:
9464796
48.

The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids.

El Ouahabi A, Thiry M, Pector V, Fuks R, Ruysschaert JM, Vandenbranden M.

FEBS Lett. 1997 Sep 8;414(2):187-92.

49.

Examination of purported probes of human CYP2B6.

Ekins S, VandenBranden M, Ring BJ, Wrighton SA.

Pharmacogenetics. 1997 Jun;7(3):165-79.

PMID:
9241656
50.

The human drug metabolizing cytochromes P450.

Wrighton SA, VandenBranden M, Ring BJ.

J Pharmacokinet Biopharm. 1996 Oct;24(5):461-73. Review.

PMID:
9131485

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