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Items: 1 to 50 of 82

1.

Targeting Ferroptosis to Iron Out Cancer.

Hassannia B, Vandenabeele P, Vanden Berghe T.

Cancer Cell. 2019 Jun 10;35(6):830-849. doi: 10.1016/j.ccell.2019.04.002. Epub 2019 May 16. Review.

PMID:
31105042
2.

Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy.

Elvas F, Vanden Berghe T, Adriaenssens Y, Vandenabeele P, Augustyns K, Staelens S, Stroobants S, Van der Veken P, Wyffels L.

Org Biomol Chem. 2019 May 15;17(19):4801-4824. doi: 10.1039/c9ob00657e.

PMID:
31033991
3.

Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB.

Webb LV, Barbarulo A, Huysentruyt J, Vanden Berghe T, Takahashi N, Ley S, Vandenabeele P, Seddon B.

Immunity. 2019 Feb 19;50(2):348-361.e4. doi: 10.1016/j.immuni.2019.01.004. Epub 2019 Feb 5.

4.

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis.

Saavedra PHV, Huang L, Ghazavi F, Kourula S, Vanden Berghe T, Takahashi N, Vandenabeele P, Lamkanfi M.

Nat Commun. 2018 Nov 19;9(1):4846. doi: 10.1038/s41467-018-07386-5.

5.

MLKL Reveals Its Friendly Face: A Role in Nerve Regeneration.

Vandenabeele P, Declercq W, Roelandt R, Vanden Berghe T.

Mol Cell. 2018 Nov 1;72(3):397-399. doi: 10.1016/j.molcel.2018.10.025.

PMID:
30388406
6.

Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids.

Vanden Berghe T, Hoste E.

Cell Death Differ. 2019 Jan;26(1):83-98. doi: 10.1038/s41418-018-0196-2. Epub 2018 Sep 10.

7.

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.

Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T.

J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25.

8.

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

Annibaldi A, Wicky John S, Vanden Berghe T, Swatek KN, Ruan J, Liccardi G, Bianchi K, Elliott PR, Choi SM, Van Coillie S, Bertin J, Wu H, Komander D, Vandenabeele P, Silke J, Meier P.

Mol Cell. 2018 Feb 15;69(4):566-580.e5. doi: 10.1016/j.molcel.2018.01.027.

9.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

10.

Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich's ataxia fibroblasts.

De Samber B, Meul E, Laforce B, De Paepe B, Smet J, De Bruyne M, De Rycke R, Bohic S, Cloetens P, Van Coster R, Vandenabeele P, Vanden Berghe T.

PLoS One. 2018 Jan 17;13(1):e0190495. doi: 10.1371/journal.pone.0190495. eCollection 2018. Erratum in: PLoS One. 2018 Apr 30;13(4):e0194850.

11.

Feasibility study for clinical application of caspase-3 inhibitors in Pemphigus vulgaris.

Hariton WVJ, Galichet A, Vanden Berghe T, Overmiller AM, Mahoney MG, Declercq W, Müller EJ.

Exp Dermatol. 2017 Dec;26(12):1274-1277. doi: 10.1111/exd.13458.

PMID:
29105150
12.

How do we fit ferroptosis in the family of regulated cell death?

Fearnhead HO, Vandenabeele P, Vanden Berghe T.

Cell Death Differ. 2017 Dec;24(12):1991-1998. doi: 10.1038/cdd.2017.149. Epub 2017 Oct 6. Review.

13.

Preconditioning with Lipopolysaccharide or Lipoteichoic Acid Protects against Staphylococcus aureus Mammary Infection in Mice.

Breyne K, Steenbrugge J, Demeyere K, Vanden Berghe T, Meyer E.

Front Immunol. 2017 Jul 24;8:833. doi: 10.3389/fimmu.2017.00833. eCollection 2017.

14.

Heavy metal suicide.

Linkermann A, Stockwell B, Vanden Berghe T.

Am J Physiol Renal Physiol. 2017 Oct 1;313(4):F959-F960. doi: 10.1152/ajprenal.00273.2017. Epub 2017 May 31. No abstract available.

15.

Initiation and execution mechanisms of necroptosis: an overview.

Grootjans S, Vanden Berghe T, Vandenabeele P.

Cell Death Differ. 2017 Jul;24(7):1184-1195. doi: 10.1038/cdd.2017.65. Epub 2017 May 12. Review.

16.

Impact of caspase-1/11, -3, -7, or IL-1β/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.

Kip E, Nazé F, Suin V, Vanden Berghe T, Francart A, Lamoral S, Vandenabeele P, Beyaert R, Van Gucht S, Kalai M.

Cell Death Discov. 2017 Mar 6;3:17012. doi: 10.1038/cddiscovery.2017.12. eCollection 2017.

17.

RIPK1 prevents aberrant ZBP1-initiated necroptosis.

Vanden Berghe T, Kaiser WJ.

Oncotarget. 2017 Jan 3;8(1):1-2. doi: 10.18632/oncotarget.13926. No abstract available.

18.

A real-time fluorometric method for the simultaneous detection of cell death type and rate.

Grootjans S, Hassannia B, Delrue I, Goossens V, Wiernicki B, Dondelinger Y, Bertrand MJ, Krysko DV, Vuylsteke M, Vandenabeele P, Vanden Berghe T.

Nat Protoc. 2016 Aug;11(8):1444-54. doi: 10.1038/nprot.2016.085. Epub 2016 Jul 14.

PMID:
27414760
19.

Molecular crosstalk between apoptosis, necroptosis, and survival signaling.

Vanden Berghe T, Kaiser WJ, Bertrand MJ, Vandenabeele P.

Mol Cell Oncol. 2015 Apr 8;2(4):e975093. doi: 10.4161/23723556.2014.975093. eCollection 2015 Oct-Dec. Review.

20.

An outline of necrosome triggers.

Vanden Berghe T, Hassannia B, Vandenabeele P.

Cell Mol Life Sci. 2016 Jun;73(11-12):2137-52. doi: 10.1007/s00018-016-2189-y. Epub 2016 Apr 6. Review.

21.

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties.

Hofmans S, Vanden Berghe T, Devisscher L, Hassannia B, Lyssens S, Joossens J, Van Der Veken P, Vandenabeele P, Augustyns K.

J Med Chem. 2016 Mar 10;59(5):2041-53. doi: 10.1021/acs.jmedchem.5b01641. Epub 2016 Feb 8.

PMID:
26696014
22.

Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue.

Vesela B, Svandova E, Vanden Berghe T, Tucker AS, Vandenabeele P, Matalova E.

J Mol Histol. 2015 Oct;46(4-5):443-55. doi: 10.1007/s10735-015-9636-1. Epub 2015 Aug 8.

PMID:
26253163
23.

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

Vanden Berghe T, Hulpiau P, Martens L, Vandenbroucke RE, Van Wonterghem E, Perry SW, Bruggeman I, Divert T, Choi SM, Vuylsteke M, Shestopalov VI, Libert C, Vandenabeele P.

Immunity. 2015 Jul 21;43(1):200-9. doi: 10.1016/j.immuni.2015.06.011. Epub 2015 Jul 7.

24.

Take my breath away: necrosis in kidney transplants kills the lungs!

Vanden Berghe T, Linkermann A.

Kidney Int. 2015 Apr;87(4):680-2. doi: 10.1038/ki.2015.13.

PMID:
25826542
25.

Mitochondria and NADPH oxidases are the major sources of TNF-α/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells.

Babu D, Leclercq G, Goossens V, Vanden Berghe T, Van Hamme E, Vandenabeele P, Lefebvre RA.

Cell Signal. 2015 Jun;27(6):1141-58. doi: 10.1016/j.cellsig.2015.02.019. Epub 2015 Feb 26.

PMID:
25725292
26.

Synchronized renal tubular cell death involves ferroptosis.

Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10.

27.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Review.

28.

Necroptosis, in vivo detection in experimental disease models.

Jouan-Lanhouet S, Riquet F, Duprez L, Vanden Berghe T, Takahashi N, Vandenabeele P.

Semin Cell Dev Biol. 2014 Nov;35:2-13. doi: 10.1016/j.semcdb.2014.08.010. Epub 2014 Aug 23. Review.

PMID:
25160988
29.

Non-apoptotic functions of caspase-7 during osteogenesis.

Svandova E, Lesot H, Vanden Berghe T, Tucker AS, Sharpe PT, Vandenabeele P, Matalova E.

Cell Death Dis. 2014 Aug 14;5:e1366. doi: 10.1038/cddis.2014.330.

30.

Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock.

Vanden Berghe T, Demon D, Bogaert P, Vandendriessche B, Goethals A, Depuydt B, Vuylsteke M, Roelandt R, Van Wonterghem E, Vandenbroecke J, Choi SM, Meyer E, Krautwald S, Declercq W, Takahashi N, Cauwels A, Vandenabeele P.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):282-91. doi: 10.1164/rccm.201308-1535OC.

PMID:
24456467
31.

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P.

Nat Rev Mol Cell Biol. 2014 Feb;15(2):135-47. doi: 10.1038/nrm3737. Review.

PMID:
24452471
32.

An inactivating caspase-11 passenger mutation muddles sepsis research.

Vanden Berghe T, Goethals A, Demon D, Bogaert P, Mak TW, Cauwels A, Vandenabeele P.

Am J Respir Crit Care Med. 2013 Jul 1;188(1):120-1. doi: 10.1164/rccm.201210-1775LE. No abstract available.

PMID:
23815731
33.

Caspase-7 participates in differentiation of cells forming dental hard tissues.

Matalova E, Lesot H, Svandova E, Vanden Berghe T, Sharpe PT, Healy C, Vandenabeele P, Tucker AS.

Dev Growth Differ. 2013 Jun;55(5):615-21. doi: 10.1111/dgd.12066. Epub 2013 May 29.

PMID:
23713787
34.

Determination of apoptotic and necrotic cell death in vitro and in vivo.

Vanden Berghe T, Grootjans S, Goossens V, Dondelinger Y, Krysko DV, Takahashi N, Vandenabeele P.

Methods. 2013 Jun 1;61(2):117-29. doi: 10.1016/j.ymeth.2013.02.011. Epub 2013 Mar 7. Review.

PMID:
23473780
35.

Caspase-7 in molar tooth development.

Matalova E, Vanden Berghe T, Svandova E, Vandenabeele P, Healy C, Sharpe PT, Tucker AS.

Arch Oral Biol. 2012 Nov;57(11):1474-81. doi: 10.1016/j.archoralbio.2012.06.009. Epub 2012 Aug 1.

PMID:
22858065
36.

Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis.

Duprez L, Bertrand MJ, Vanden Berghe T, Dondelinger Y, Festjens N, Vandenabeele P.

J Biol Chem. 2012 Apr 27;287(18):14863-72. doi: 10.1074/jbc.M111.288670. Epub 2012 Feb 23.

37.

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome.

Duprez L, Takahashi N, Van Hauwermeiren F, Vandendriessche B, Goossens V, Vanden Berghe T, Declercq W, Libert C, Cauwels A, Vandenabeele P.

Immunity. 2011 Dec 23;35(6):908-18. doi: 10.1016/j.immuni.2011.09.020.

38.

Beclin1: a role in membrane dynamics and beyond.

Wirawan E, Lippens S, Vanden Berghe T, Romagnoli A, Fimia GM, Piacentini M, Vandenabeele P.

Autophagy. 2012 Jan;8(1):6-17. doi: 10.4161/auto.8.1.16645. Epub 2012 Jan 1. Review.

PMID:
22170155
39.

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members.

Vanlangenakker N, Bertrand MJ, Bogaert P, Vandenabeele P, Vanden Berghe T.

Cell Death Dis. 2011 Nov 17;2:e230. doi: 10.1038/cddis.2011.111.

40.

Many stimuli pull the necrotic trigger, an overview.

Vanlangenakker N, Vanden Berghe T, Vandenabeele P.

Cell Death Differ. 2012 Jan;19(1):75-86. doi: 10.1038/cdd.2011.164. Epub 2011 Nov 11. Review.

41.

Autophagy: for better or for worse.

Wirawan E, Vanden Berghe T, Lippens S, Agostinis P, Vandenabeele P.

Cell Res. 2012 Jan;22(1):43-61. doi: 10.1038/cr.2011.152. Epub 2011 Sep 13. Review.

42.

Fine-tuning nucleophosmin in macrophage differentiation and activation.

Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, Jacquel A, Cally R, Manoury B, Vanden Berghe T, Vandenabeele P, Droin N, Solary E.

Blood. 2011 Oct 27;118(17):4694-704. doi: 10.1182/blood-2011-03-341255. Epub 2011 Aug 29.

43.

Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor κB signaling.

Kersse K, Lamkanfi M, Bertrand MJ, Vanden Berghe T, Vandenabeele P.

J Biol Chem. 2011 Oct 14;286(41):35874-82. doi: 10.1074/jbc.M111.242321. Epub 2011 Aug 23.

44.

NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation.

Provoost S, Maes T, Pauwels NS, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Tournoy KG.

J Immunol. 2011 Sep 15;187(6):3331-7. doi: 10.4049/jimmunol.1004062. Epub 2011 Aug 15.

45.

The death-fold superfamily of homotypic interaction motifs.

Kersse K, Verspurten J, Vanden Berghe T, Vandenabeele P.

Trends Biochem Sci. 2011 Oct;36(10):541-52. doi: 10.1016/j.tibs.2011.06.006. Epub 2011 Jul 26. Review.

PMID:
21798745
46.

Programmed necrosis from molecules to health and disease.

Galluzzi L, Vanden Berghe T, Vanlangenakker N, Buettner S, Eisenberg T, Vandenabeele P, Madeo F, Kroemer G.

Int Rev Cell Mol Biol. 2011;289:1-35. doi: 10.1016/B978-0-12-386039-2.00001-8. Review.

PMID:
21749897
47.

Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD.

Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG.

Eur Respir J. 2011 Nov;38(5):1019-28. doi: 10.1183/09031936.00158110. Epub 2011 May 26.

48.

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality.

Remijsen Q, Kuijpers TW, Wirawan E, Lippens S, Vandenabeele P, Vanden Berghe T.

Cell Death Differ. 2011 Apr;18(4):581-8. doi: 10.1038/cdd.2011.1. Epub 2011 Feb 4. Review.

49.

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation.

Remijsen Q, Vanden Berghe T, Wirawan E, Asselbergh B, Parthoens E, De Rycke R, Noppen S, Delforge M, Willems J, Vandenabeele P.

Cell Res. 2011 Feb;21(2):290-304. doi: 10.1038/cr.2010.150. Epub 2010 Nov 9.

50.

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.

Vanlangenakker N, Vanden Berghe T, Bogaert P, Laukens B, Zobel K, Deshayes K, Vucic D, Fulda S, Vandenabeele P, Bertrand MJ.

Cell Death Differ. 2011 Apr;18(4):656-65. doi: 10.1038/cdd.2010.138. Epub 2010 Nov 5.

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