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Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis.

Saini S, Poelmans J, Korf H, Dooley JL, Liang S, Manshian BB, Verbeke R, Soenen SJ, Vande Velde G, Lentacker I, Lagrou K, Liston A, Gysemans C, De Smedt SC, Himmelreich U.

iScience. 2019 Sep 18;20:184-194. doi: 10.1016/j.isci.2019.09.022. [Epub ahead of print]


Automated computerized image analysis for the user-independent evaluation of disease severity in preclinical models of NAFLD/NASH.

De Rudder M, Bouzin C, Nachit M, Louvegny H, Vande Velde G, Julé Y, Leclercq IA.

Lab Invest. 2019 Sep 10. doi: 10.1038/s41374-019-0315-9. [Epub ahead of print]


AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice.

Pironet A, Syam N, Vandewiele F, Van den Haute C, Kerselaers S, Pinto S, Vande Velde G, Gijsbers R, Vennekens R.

Front Physiol. 2019 Jun 27;10:802. doi: 10.3389/fphys.2019.00802. eCollection 2019.


Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis.

Vanherp L, Ristani A, Poelmans J, Hillen A, Lagrou K, Janbon G, Brock M, Himmelreich U, Vande Velde G.

Dis Model Mech. 2019 Jun 17;12(6). pii: dmm039123. doi: 10.1242/dmm.039123.


Dermal exposure determines the outcome of repeated airway exposure in a long-term chemical-induced asthma-like mouse model.

Pollaris L, Van Den Broucke S, Decaesteker T, Cremer J, Seys S, Devos FC, Provoost S, Maes T, Verbeken E, Vande Velde G, Nemery B, Hoet PHM, Vanoirbeek JAJ.

Toxicology. 2019 Jun 1;421:84-92. doi: 10.1016/j.tox.2019.05.001. Epub 2019 May 6.


Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves.

Liesenborghs L, Meyers S, Lox M, Criel M, Claes J, Peetermans M, Trenson S, Vande Velde G, Vanden Berghe P, Baatsen P, Missiakas D, Schneewind O, Peetermans WE, Hoylaerts MF, Vanassche T, Verhamme P.

Eur Heart J. 2019 Oct 14;40(39):3248-3259. doi: 10.1093/eurheartj/ehz175.


Local pulmonary drug delivery in the preterm rabbit: feasibility and efficacy of daily intratracheal injections.

Salaets T, Gie A, Jimenez J, Aertgeerts M, Gheysens O, Vande Velde G, Koole M, Murgia X, Casiraghi C, Ricci F, Salomone F, Villetti G, Allegaert K, Deprest J, Toelen J.

Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1;316(4):L589-L597. doi: 10.1152/ajplung.00255.2018. Epub 2019 Jan 24.


A Label-free Multicolor Optical Surface Tomography (ALMOST) imaging method for nontransparent 3D samples.

Kerstens A, Corthout N, Pavie B, Huang Z, Vernaillen F, Vande Velde G, Munck S.

BMC Biol. 2019 Jan 7;17(1):1. doi: 10.1186/s12915-018-0614-4.


Monitoring of Fluconazole and Caspofungin Activity against In Vivo Candida glabrata Biofilms by Bioluminescence Imaging.

Persyn A, Rogiers O, Brock M, Vande Velde G, Lamkanfi M, Jacobsen ID, Himmelreich U, Lagrou K, Van Dijck P, Kucharíková S.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01555-18. doi: 10.1128/AAC.01555-18. Print 2019 Feb.


Translation from murine to human lung imaging using x-ray dark field radiography: A simulation study.

Vignero J, Marshall NW, Vande Velde G, Bliznakova K, Bosmans H.

PLoS One. 2018 Oct 29;13(10):e0206302. doi: 10.1371/journal.pone.0206302. eCollection 2018.


Fate of mesoangioblasts in a vaginal birth injury model: influence of the route of administration.

Mori da Cunha MGMC, Giacomazzi G, Callewaert G, Hympanova L, Russo F, Vande Velde G, Gijsbers R, Albersen M, Sampaolesi M, Deprest J.

Sci Rep. 2018 Jul 13;8(1):10604. doi: 10.1038/s41598-018-28967-w.


X-ray-Based 3D Virtual Histology-Adding the Next Dimension to Histological Analysis.

Albers J, Pacilé S, Markus MA, Wiart M, Vande Velde G, Tromba G, Dullin C.

Mol Imaging Biol. 2018 Oct;20(5):732-741. doi: 10.1007/s11307-018-1246-3. Review.


A Multimodal Imaging Approach Enables In Vivo Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis.

Poelmans J, Himmelreich U, Vanherp L, Zhai L, Hillen A, Holvoet B, Belderbos S, Brock M, Maertens J, Vande Velde G, Lagrou K.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00240-18. doi: 10.1128/AAC.00240-18. Print 2018 Jul.


Bioluminescence imaging increases in vivo screening efficiency for antifungal activity against device-associated Candida albicans biofilms.

Vande Velde G, Kucharíková S, Van Dijck P, Himmelreich U.

Int J Antimicrob Agents. 2018 Jul;52(1):42-51. doi: 10.1016/j.ijantimicag.2018.03.007. Epub 2018 Mar 20.


Bronchoscopic fibered confocal fluorescence microscopy for longitudinal in vivo assessment of pulmonary fungal infections in free-breathing mice.

Vanherp L, Poelmans J, Hillen A, Govaerts K, Belderbos S, Buelens T, Lagrou K, Himmelreich U, Vande Velde G.

Sci Rep. 2018 Feb 14;8(1):3009. doi: 10.1038/s41598-018-20545-4.


Irritant-induced asthma to hypochlorite in mice due to impairment of the airway barrier.

Van Den Broucke S, Pollaris L, Vande Velde G, Verbeken E, Nemery B, Vanoirbeek J, Hoet P.

Arch Toxicol. 2018 Apr;92(4):1551-1561. doi: 10.1007/s00204-018-2161-8. Epub 2018 Jan 24.


Genetically encoded iron-associated proteins as MRI reporters for molecular and cellular imaging.

Naumova AV, Vande Velde G.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Mar;10(2). doi: 10.1002/wnan.1482. Epub 2017 Jul 14. Review.


Image-based in vivo assessment of targeting accuracy of stereotactic brain surgery in experimental rodent models.

Rangarajan JR, Vande Velde G, van Gent F, De Vloo P, Dresselaers T, Depypere M, van Kuyck K, Nuttin B, Himmelreich U, Maes F.

Sci Rep. 2016 Nov 30;6:38058. doi: 10.1038/srep38058.


Longitudinal microcomputed tomography-derived biomarkers for lung metastasis detection in a syngeneic mouse model: added value to bioluminescence imaging.

Marien E, Hillen A, Vanderhoydonc F, Swinnen JV, Vande Velde G.

Lab Invest. 2017 Jan;97(1):24-33. doi: 10.1038/labinvest.2016.114. Epub 2016 Nov 21.


De novo design of a biologically active amyloid.

Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet P, Vande Velde G, Verfaillie C, Kaminski CF, De Strooper B, Hammarström P, Nilsson KP, Serpell L, Schymkowitz J, Rousseau F.

Science. 2016 Nov 11;354(6313). pii: aah4949.


The Use of Toll-like Receptor 4 Agonist to Reshape the Immune Signature in Ovarian Cancer.

Vindevogel E, Baert T, VAN Hoylandt A, Verbist G, Vande Velde G, Garg AD, Agostinis P, Vergote I, Coosemans AN.

Anticancer Res. 2016 Nov;36(11):5781-5792.


Searching for the Optimal Fluorophore to Label Antimicrobial Peptides.

Zhao C, Fernandez A, Avlonitis N, Vande Velde G, Bradley M, Read ND, Vendrell M.

ACS Comb Sci. 2016 Nov 14;18(11):689-696. Epub 2016 Oct 20.


Development of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging.

D'Hollander A, Mathieu E, Jans H, Vande Velde G, Stakenborg T, Van Dorpe P, Himmelreich U, Lagae L.

Int J Nanomedicine. 2016 Aug 4;11:3703-14. doi: 10.2147/IJN.S91340. eCollection 2016.


Refine, reduce, replace: Imaging of fibrosis and arthritis in animal models.

Marenzana M, Vande Velde G.

Best Pract Res Clin Rheumatol. 2015 Dec;29(6):715-40. doi: 10.1016/j.berh.2016.02.001. Epub 2016 Mar 14. Review.


Longitudinal, in vivo assessment of invasive pulmonary aspergillosis in mice by computed tomography and magnetic resonance imaging.

Poelmans J, Hillen A, Vanherp L, Govaerts K, Maertens J, Dresselaers T, Himmelreich U, Lagrou K, Vande Velde G.

Lab Invest. 2016 Jun;96(6):692-704. doi: 10.1038/labinvest.2016.45. Epub 2016 Mar 28.


Transplacental sildenafil rescues lung abnormalities in the rabbit model of diaphragmatic hernia.

Russo FM, Toelen J, Eastwood MP, Jimenez J, Miyague AH, Vande Velde G, DeKoninck P, Himmelreich U, Vergani P, Allegaert K, Deprest J.

Thorax. 2016 Jun;71(6):517-25. doi: 10.1136/thoraxjnl-2015-207949. Epub 2016 Mar 17.


Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors.

Leten C, Trekker J, Struys T, Roobrouck VD, Dresselaers T, Vande Velde G, Lambrichts I, Verfaillie CM, Himmelreich U.

Stem Cells Int. 2016;2016:4095072. doi: 10.1155/2016/4095072. Epub 2016 Jan 6.


Immediate postoperative changes in synthetic meshes - In vivo measurements.

Sindhwani N, Liaquat Z, Urbankova I, Vande Velde G, Feola A, Deprest J.

J Mech Behav Biomed Mater. 2015 Mar;55:228-235. doi: 10.1016/j.jmbbm.2015.10.015. Epub 2015 Oct 30.


Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume.

Vande Velde G, Poelmans J, De Langhe E, Hillen A, Vanoirbeek J, Himmelreich U, Lories RJ.

Dis Model Mech. 2016 Jan;9(1):91-8. doi: 10.1242/dmm.020321. Epub 2015 Nov 12.


Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach.

Leten C, Trekker J, Struys T, Dresselaers T, Gijsbers R, Vande Velde G, Lambrichts I, Van Der Linden A, Verfaillie CM, Himmelreich U.

Stem Cell Res Ther. 2015 Sep 7;6:163. doi: 10.1186/s13287-015-0157-3.


Visualization of delayed release of compounds from pH-sensitive capsules in vitro and in vivo in a hamster model.

Staelens D, Liang S, Appeltans B, Van de Wouwer M, Van den Mooter G, Van Assche G, Himmelreich U, Vande Velde G.

Contrast Media Mol Imaging. 2016 Jan-Feb;11(1):24-31. doi: 10.1002/cmmi.1654. Epub 2015 Jul 20.


A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis.

Verreet T, Quintens R, Van Dam D, Verslegers M, Tanori M, Casciati A, Neefs M, Leysen L, Michaux A, Janssen A, D'Agostino E, Vande Velde G, Baatout S, Moons L, Pazzaglia S, Saran A, Himmelreich U, De Deyn PP, Benotmane MA.

J Neurodev Disord. 2015;7(1):3. doi: 10.1186/1866-1955-7-3. Epub 2015 Jan 9.


Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity.

Vande Velde G, De Langhe E, Poelmans J, Bruyndonckx P, d'Agostino E, Verbeken E, Bogaerts R, Lories R, Himmelreich U.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1;309(3):L271-9. doi: 10.1152/ajplung.00098.2015. Epub 2015 May 29.


Correction: A Causal Relation between Bioluminescence and Oxygen to Quantify the Cell Niche.

Lambrechts D, Roeffaers M, Goossens K, Hofkens J, Vande Velde G, Van de Putte T, Schrooten J, Van Oosterwyck H.

PLoS One. 2015 May 28;10(5):e0128852. doi: 10.1371/journal.pone.0128852. eCollection 2015. No abstract available.


Candida albicans biofilm development on medically-relevant foreign bodies in a mouse subcutaneous model followed by bioluminescence imaging.

Kucharíková S, Vande Velde G, Himmelreich U, Van Dijck P.

J Vis Exp. 2015 Jan 27;(95):52239. doi: 10.3791/52239.


Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections.

Peetermans M, Vanassche T, Liesenborghs L, Claes J, Vande Velde G, Kwiecinksi J, Jin T, De Geest B, Hoylaerts MF, Lijnen RH, Verhamme P.

BMC Microbiol. 2014 Dec 17;14:310. doi: 10.1186/s12866-014-0310-7.


Controlling and monitoring stem cell safety in vivo in an experimental rodent model.

Leten C, Roobrouck VD, Struys T, Burns TC, Dresselaers T, Vande Velde G, Santermans J, Lo Nigro A, Ibrahimi A, Gijsbers R, Eggermont K, Lambrichts I, Verfaillie CM, Himmelreich U.

Stem Cells. 2014 Nov;32(11):2833-44. doi: 10.1002/stem.1819.


Bioluminescence imaging of stroke-induced endogenous neural stem cell response.

Vandeputte C, Reumers V, Aelvoet SA, Thiry I, De Swaef S, Van den Haute C, Pascual-Brazo J, Farr TD, Vande Velde G, Hoehn M, Himmelreich U, Van Laere K, Debyser Z, Gijsbers R, Baekelandt V.

Neurobiol Dis. 2014 Sep;69:144-55. doi: 10.1016/j.nbd.2014.05.014. Epub 2014 May 27.


A causal relation between bioluminescence and oxygen to quantify the cell niche.

Lambrechts D, Roeffaers M, Goossens K, Hofkens J, Vande Velde G, Van de Putte T, Schrooten J, Van Oosterwyck H.

PLoS One. 2014 May 19;9(5):e97572. doi: 10.1371/journal.pone.0097572. eCollection 2014. Erratum in: PLoS One. 2015;10(5):e0128852. Vande Velde, Greetje [added].


Reporter gene approaches for mapping cell fate decisions by MRI: promises and pitfalls.

Vande Velde G, Himmelreich U, Neeman M.

Contrast Media Mol Imaging. 2013 Nov-Dec;8(6):424-31. doi: 10.1002/cmmi.1590. Review.


Bioluminescence imaging of fungal biofilm development in live animals.

Vande Velde G, Kucharíková S, Van Dijck P, Himmelreich U.

Methods Mol Biol. 2014;1098:153-67. doi: 10.1007/978-1-62703-718-1_13.


Towards non-invasive monitoring of pathogen-host interactions during Candida albicans biofilm formation using in vivo bioluminescence.

Vande Velde G, Kucharíková S, Schrevens S, Himmelreich U, Van Dijck P.

Cell Microbiol. 2014 Jan;16(1):115-30. doi: 10.1111/cmi.12184. Epub 2013 Sep 12.


Resorbable scaffold based chronic neural electrode arrays.

Ceyssens F, van Kuyck K, Vande Velde G, Welkenhuysen M, Stappers L, Nuttin B, Puers R.

Biomed Microdevices. 2013 Jun;15(3):481-93. doi: 10.1007/s10544-013-9748-x.


In situ labeling and imaging of endogenous neural stem cell proliferation and migration.

Vande Velde G, Couillard-Després S, Aigner L, Himmelreich U, van der Linden A.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 Nov-Dec;4(6):663-79. doi: 10.1002/wnan.1192. Epub 2012 Aug 29. Review.


Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography.

De Langhe E, Vande Velde G, Hostens J, Himmelreich U, Nemery B, Luyten FP, Vanoirbeek J, Lories RJ.

PLoS One. 2012;7(8):e43123. doi: 10.1371/journal.pone.0043123. Epub 2012 Aug 13.


Quantitative evaluation of MRI-based tracking of ferritin-labeled endogenous neural stem cell progeny in rodent brain.

Vande Velde G, Raman Rangarajan J, Vreys R, Guglielmetti C, Dresselaers T, Verhoye M, Van der Linden A, Debyser Z, Baekelandt V, Maes F, Himmelreich U.

Neuroimage. 2012 Aug 1;62(1):367-80. doi: 10.1016/j.neuroimage.2012.04.040. Epub 2012 May 1.


MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes.

Soenen SJ, De Meyer SF, Dresselaers T, Vande Velde G, Pareyn IM, Braeckmans K, De Cuyper M, Himmelreich U, Vanhoorelbeke KI.

Biomaterials. 2011 Jun;32(17):4140-50. doi: 10.1016/j.biomaterials.2011.02.037. Epub 2011 Mar 17.


Evaluation of the specificity and sensitivity of ferritin as an MRI reporter gene in the mouse brain using lentiviral and adeno-associated viral vectors.

Vande Velde G, Rangarajan JR, Toelen J, Dresselaers T, Ibrahimi A, Krylychkina O, Vreys R, Van der Linden A, Maes F, Debyser Z, Himmelreich U, Baekelandt V.

Gene Ther. 2011 Jun;18(6):594-605. doi: 10.1038/gt.2011.2. Epub 2011 Feb 24.


Magnetic resonance imaging and spectroscopy methods for molecular imaging.

Vande Velde G, Baekelandt V, Dresselaers T, Himmelreich U.

Q J Nucl Med Mol Imaging. 2009 Dec;53(6):565-85. Review.

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