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Items: 40


E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1.

Drews CM, Case S, Vande Pol SB.

PLoS Pathog. 2019 Apr 19;15(4):e1007575. doi: 10.1371/journal.ppat.1007575. eCollection 2019 Apr.


Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization.

Webb Strickland S, Brimer N, Lyons C, Vande Pol SB.

Virology. 2018 Mar;516:127-138. doi: 10.1016/j.virol.2018.01.003. Epub 2018 Jan 12.


Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness.

Brimer N, Drews CM, Vande Pol SB.

PLoS Pathog. 2017 Dec 27;13(12):e1006781. doi: 10.1371/journal.ppat.1006781. eCollection 2017 Dec.


Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.

Petropoulos C, Oddou C, Emadali A, Hiriart-Bryant E, Boyault C, Faurobert E, Vande Pol S, Kim-Kaneyama JR, Kraut A, Coute Y, Block M, Albiges-Rizo C, Destaing O.

J Cell Biol. 2016 Jun 6;213(5):585-99. doi: 10.1083/jcb.201510036.


The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC.

Strickland SW, Vande Pol S.

J Virol. 2016 May 27;90(12):5611-5621. doi: 10.1128/JVI.00411-16. Print 2016 Jun 15.


Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.

Martinez-Zapien D, Ruiz FX, Poirson J, Mitschler A, Ramirez J, Forster A, Cousido-Siah A, Masson M, Vande Pol S, Podjarny A, Travé G, Zanier K.

Nature. 2016 Jan 28;529(7587):541-5. doi: 10.1038/nature16481. Epub 2016 Jan 20.


Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems.

Vande Pol S.

PLoS Pathog. 2015 Oct 15;11(10):e1005138. doi: 10.1371/journal.ppat.1005138. eCollection 2015 Oct. Review. No abstract available.


Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6.

Brimer N, Wade R, Vande Pol S.

J Virol. 2014 Sep 1;88(17):9927-33. doi: 10.1128/JVI.00552-14. Epub 2014 Jun 18.


Papillomavirus E6 PDZ interactions can be replaced by repression of p53 to promote episomal human papillomavirus genome maintenance.

Brimer N, Vande Pol SB.

J Virol. 2014 Mar;88(5):3027-30. doi: 10.1128/JVI.02360-13. Epub 2013 Dec 18.


Papillomavirus E6 oncoproteins.

Vande Pol SB, Klingelhutz AJ.

Virology. 2013 Oct;445(1-2):115-37. doi: 10.1016/j.virol.2013.04.026. Epub 2013 May 24. Review.


Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.

Zanier K, Charbonnier S, Sidi AO, McEwen AG, Ferrario MG, Poussin-Courmontagne P, Cura V, Brimer N, Babah KO, Ansari T, Muller I, Stote RH, Cavarelli J, Vande Pol S, Travé G.

Science. 2013 Feb 8;339(6120):694-8. doi: 10.1126/science.1229934.


Peptide interactions stabilize and restructure human papillomavirus type 16 E6 to interact with p53.

Ansari T, Brimer N, Vande Pol SB.

J Virol. 2012 Oct;86(20):11386-91. Epub 2012 Aug 15.


Paxillin contracts the osteoclast cytoskeleton.

Zou W, Deselm CJ, Broekelmann TJ, Mecham RP, Vande Pol S, Choi K, Teitelbaum SL.

J Bone Miner Res. 2012 Dec;27(12):2490-500. doi: 10.1002/jbmr.1706.


Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling.

Brimer N, Lyons C, Wallberg AE, Vande Pol SB.

Oncogene. 2012 Oct 25;31(43):4639-46. doi: 10.1038/onc.2011.589. Epub 2012 Jan 16.


Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.

Wade R, Brimer N, Lyons C, Vande Pol S.

J Biol Chem. 2011 Nov 4;286(44):37932-44. doi: 10.1074/jbc.M111.294504. Epub 2011 Sep 7.


Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway.

Jha S, Vande Pol S, Banerjee NS, Dutta AB, Chow LT, Dutta A.

Mol Cell. 2010 Jun 11;38(5):700-11. doi: 10.1016/j.molcel.2010.05.020.


E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo.

Zanier K, Ruhlmann C, Melin F, Masson M, Ould M'hamed Ould Sidi A, Bernard X, Fischer B, Brino L, Ristriani T, Rybin V, Baltzinger M, Vande Pol S, Hellwig P, Schultz P, Travé G.

J Mol Biol. 2010 Feb 12;396(1):90-104. doi: 10.1016/j.jmb.2009.11.022. Epub 2009 Nov 13.


Transformation by bovine papillomavirus type 1 E6 requires paxillin.

Wade R, Brimer N, Vande Pol S.

J Virol. 2008 Jun;82(12):5962-6. doi: 10.1128/JVI.02747-07. Epub 2008 Apr 2.


Human papillomavirus E6 regulates the cytoskeleton dynamics of keratinocytes through targeted degradation of p53.

Cooper B, Brimer N, Vande Pol SB.

J Virol. 2007 Nov;81(22):12675-9. Epub 2007 Sep 5.


Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins.

Jing M, Bohl J, Brimer N, Kinter M, Vande Pol SB.

J Virol. 2007 Mar;81(5):2231-9. Epub 2006 Dec 13.


Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein.

Brimer N, Lyons C, Vande Pol SB.

Virology. 2007 Feb 20;358(2):303-10. Epub 2006 Oct 4.


Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1.

Cooper B, Brimer N, Stoler M, Vande Pol SB.

Virology. 2006 Nov 10;355(1):102-14. Epub 2006 Aug 8.


Requirement of E6AP and the features of human papillomavirus E6 necessary to support degradation of p53.

Cooper B, Schneider S, Bohl J, Jiang Yh, Beaudet A, Vande Pol S.

Virology. 2003 Feb 1;306(1):87-99.


Competitive binding to a charged leucine motif represses transformation by a papillomavirus E6 oncoprotein.

Bohl J, Das K, Dasgupta B, Vande Pol SB.

Virology. 2000 May 25;271(1):163-70.


Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis.

Cross JV, Deak JC, Rich EA, Qian Y, Lewis M, Parrott LA, Mochida K, Gustafson D, Vande Pol S, Templeton DJ.

J Biol Chem. 1999 Oct 29;274(44):31150-4.


PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

Zheng P, Eastman J, Vande Pol S, Pimplikar SW.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14745-50.


Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.

Petricoin E 3rd, David M, Fang H, Grimley P, Larner AC, Vande Pol S.

Mol Cell Biol. 1994 Feb;14(2):1477-86.


Repression of bovine papillomavirus type 1 transcription by the E1 replication protein.

Sandler AB, Vande Pol SB, Spalholz BA.

J Virol. 1993 Sep;67(9):5079-87.

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