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Items: 1 to 50 of 75

1.

Combination Therapies Targeting HDAC and IKK in Solid Tumors.

Vancurova I, Uddin MM, Zou Y, Vancura A.

Trends Pharmacol Sci. 2018 Mar;39(3):295-306. doi: 10.1016/j.tips.2017.11.008. Epub 2017 Dec 9. Review.

PMID:
29233541
2.

Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells.

Gatla HR, Zou Y, Uddin MM, Vancurova I.

Oncotarget. 2017 Aug 7;8(41):70798-70810. doi: 10.18632/oncotarget.19990. eCollection 2017 Sep 19.

3.

Metformin induces protein acetylation in cancer cells.

Vancura A, Vancurova I.

Oncotarget. 2017 Jun 20;8(25):39939-39940. doi: 10.18632/oncotarget.17829. No abstract available.

4.

HDAC/IKK inhibition therapies in solid tumors.

Vancurova I, Gatla HR, Vancura A.

Oncotarget. 2017 May 23;8(21):34030-34031. doi: 10.18632/oncotarget.17512. No abstract available.

5.

Histone Deacetylase (HDAC) Inhibition Induces IκB Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells.

Gatla HR, Zou Y, Uddin MM, Singha B, Bu P, Vancura A, Vancurova I.

J Biol Chem. 2017 Mar 24;292(12):5043-5054. doi: 10.1074/jbc.M116.771014. Epub 2017 Feb 6.

6.

N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway.

Pekson R, Poltoratsky V, Gorasiya S, Sundaram S, Ashby CR, Vancurova I, Reznik SE.

Mol Med. 2016 Oct 24;22. doi: 10.2119/molmed.2016.00017. [Epub ahead of print]

7.

Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer Cells.

Galdieri L, Gatla H, Vancurova I, Vancura A.

J Biol Chem. 2016 Nov 25;291(48):25154-25166. Epub 2016 Oct 12.

8.

DMF: a promising therapeutic option in CTCL.

Vancurova I.

Blood. 2016 Aug 11;128(6):745-6. doi: 10.1182/blood-2016-06-722462. No abstract available.

9.

Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients.

Hensler M, Vančurová I, Becht E, Palata O, Strnad P, Tesařová P, Čabiňaková M, Švec D, Kubista M, Bartůňková J, Špíšek R, Sojka L.

Oncoimmunology. 2015 Dec 10;5(4):e1102827. eCollection 2016 Apr.

10.

IKK inhibition increases bortezomib effectiveness in ovarian cancer.

Singha B, Gatla HR, Phyo S, Patel A, Chen ZS, Vancurova I.

Oncotarget. 2015 Sep 22;6(28):26347-58. doi: 10.18632/oncotarget.4613.

11.

Anticancer drug bortezomib increases interleukin-8 expression in human monocytes.

Sanacora S, Urdinez J, Chang TP, Vancurova I.

Biochem Biophys Res Commun. 2015 May 1;460(2):375-9. doi: 10.1016/j.bbrc.2015.03.041. Epub 2015 Mar 16.

12.

Transcriptional regulation of chemokine expression in ovarian cancer.

Singha B, Gatla HR, Vancurova I.

Biomolecules. 2015 Mar 17;5(1):223-43. doi: 10.3390/biom5010223. Review.

13.

Bortezomib inhibits expression of TGF-β1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.

Chang TP, Poltoratsky V, Vancurova I.

J Immunol. 2015 Mar 15;194(6):2942-53. doi: 10.4049/jimmunol.1402610. Epub 2015 Feb 13.

14.

Bcl3 regulates pro-survival and pro-inflammatory gene expression in cutaneous T-cell lymphoma.

Chang TP, Vancurova I.

Biochim Biophys Acta. 2014 Nov;1843(11):2620-30. doi: 10.1016/j.bbamcr.2014.07.012. Epub 2014 Jul 30.

15.

Analysis of TGFβ1 and IL-10 transcriptional regulation in CTCL cells by chromatin immunoprecipitation.

Chang TP, Kim M, Vancurova I.

Methods Mol Biol. 2014;1172:329-41. doi: 10.1007/978-1-4939-0928-5_30.

PMID:
24908319
16.

Chromatin immunoprecipitation analysis of bortezomib-mediated inhibition of NFκB recruitment to IL-1β and TNFα gene promoters in human macrophages.

Sanacora S, Chang TP, Vancurova I.

Methods Mol Biol. 2014;1172:315-27. doi: 10.1007/978-1-4939-0928-5_29.

PMID:
24908318
17.

Quantitative analysis of bortezomib-induced IL-8 gene expression in ovarian cancer cells.

Singha B, Phyo SA, Gatla HR, Vancurova I.

Methods Mol Biol. 2014;1172:295-304. doi: 10.1007/978-1-4939-0928-5_27.

PMID:
24908316
18.

Western analysis of intracellular interleukin-8 in human mononuclear leukocytes.

Miskolci V, Hodgson L, Cox D, Vancurova I.

Methods Mol Biol. 2014;1172:285-93. doi: 10.1007/978-1-4939-0928-5_26.

19.

Evaluating cytoplasmic and nuclear levels of inflammatory cytokines in cancer cells by western blotting.

Gatla HR, Singha B, Persaud V, Vancurova I.

Methods Mol Biol. 2014;1172:271-83. doi: 10.1007/978-1-4939-0928-5_25.

PMID:
24908314
20.

Anti-inflammatory actions of endogenous and exogenous interleukin-10 versus glucocorticoids on macrophage functions of the newly born.

Kasat K, Patel H, Predtechenska O, Vancurova I, Davidson D.

J Perinatol. 2014 May;34(5):380-5. doi: 10.1038/jp.2014.16. Epub 2014 Feb 13.

21.

High hydrostatic pressure induces immunogenic cell death in human tumor cells.

Fucikova J, Moserova I, Truxova I, Hermanova I, Vancurova I, Partlova S, Fialova A, Sojka L, Cartron PF, Houska M, Rob L, Bartunkova J, Spisek R.

Int J Cancer. 2014 Sep 1;135(5):1165-77. doi: 10.1002/ijc.28766. Epub 2014 Feb 20.

22.

Proteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cells.

Singha B, Gatla HR, Manna S, Chang TP, Sanacora S, Poltoratsky V, Vancura A, Vancurova I.

J Biol Chem. 2014 Jan 31;289(5):2687-700. doi: 10.1074/jbc.M113.502641. Epub 2013 Dec 11.

23.

NFκB function and regulation in cutaneous T-cell lymphoma.

Chang TP, Vancurova I.

Am J Cancer Res. 2013 Nov 1;3(5):433-45. Review.

24.

Proteasome inhibition by bortezomib increases IL-8 expression in androgen-independent prostate cancer cells: the role of IKKα.

Manna S, Singha B, Phyo SA, Gatla HR, Chang TP, Sanacora S, Ramaswami S, Vancurova I.

J Immunol. 2013 Sep 1;191(5):2837-46. doi: 10.4049/jimmunol.1300895. Epub 2013 Jul 26.

25.
26.

Gene expression profile of endotoxin-stimulated leukocytes of the term new born: control of cytokine gene expression by interleukin-10.

Davidson D, Zaytseva A, Miskolci V, Castro-Alcaraz S, Vancurova I, Patel H.

PLoS One. 2013;8(1):e53641. doi: 10.1371/journal.pone.0053641. Epub 2013 Jan 11.

27.

Novel human multiple myeloma cell line UHKT-893.

Uherková L, Vančurová I, Vyhlídalová I, Pleschnerová M, Spička I, Mihalová R, Březinová J, Hodný Z, Cermáková K, Polanská V, Marinov I, Jedelský PL, Kuželová K, Stöckbauer P.

Leuk Res. 2013 Mar;37(3):320-6. doi: 10.1016/j.leukres.2012.12.004. Epub 2013 Jan 3.

PMID:
23290585
28.

Regulation and function of nuclear IκBα in inflammation and cancer.

Vancurova I, Vancura A.

Am J Clin Exp Immunol. 2012 May 25;1(1):56-66. Print 2012.

29.

Chromatin immunoprecipitation analysis of NFκB transcriptional regulation by nuclear IκBα in human macrophages.

Ramaswami S, Manna S, Juvekar A, Kennedy S, Vancura A, Vancurova I.

Methods Mol Biol. 2012;809:121-34. doi: 10.1007/978-1-61779-376-9_8.

PMID:
22113272
30.

Electrophoretic mobility shift assay analysis of NFκB transcriptional regulation by nuclear IκBα.

Juvekar A, Ramaswami S, Manna S, Chang TP, Zubair A, Vancurova I.

Methods Mol Biol. 2012;809:49-62. doi: 10.1007/978-1-61779-376-9_3.

PMID:
22113267
31.

Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.

Juvekar A, Manna S, Ramaswami S, Chang TP, Vu HY, Ghosh CC, Celiker MY, Vancurova I.

Mol Cancer Res. 2011 Feb;9(2):183-94. doi: 10.1158/1541-7786.MCR-10-0368. Epub 2011 Jan 11.

32.

Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IκBα.

Ghosh CC, Ramaswami S, Juvekar A, Vu HY, Galdieri L, Davidson D, Vancurova I.

J Immunol. 2010 Sep 15;185(6):3685-93. doi: 10.4049/jimmunol.0902230. Epub 2010 Aug 9.

33.

Transcriptional control of cytokine release from monocytes of the newborn: effects of endogenous and exogenous interleukin-10 versus dexamethasone.

Chusid LA, Pereira-Argenziano L, Miskolci V, Vancurova I, Davidson D.

Neonatology. 2010;97(2):108-16. doi: 10.1159/000235807. Epub 2009 Aug 28.

34.

Interleukin-10 versus dexamethasone: effects on polymorphonuclear leukocyte functions of the newborn.

Citarella BV, Miskolci V, Vancurova I, Davidson D.

Pediatr Res. 2009 Apr;65(4):425-9. doi: 10.1203/PDR.0b013e318199384d.

35.

Analysis of nucleocytoplasmic shuttling of NF kappa B proteins in human leukocytes.

Ghosh CC, Vu HY, Mujo T, Vancurova I.

Methods Mol Biol. 2008;457:279-92.

PMID:
19066035
36.

Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.

Vu HY, Juvekar A, Ghosh C, Ramaswami S, Le DH, Vancurova I.

Arch Biochem Biophys. 2008 Jul 15;475(2):156-63. doi: 10.1016/j.abb.2008.04.026. Epub 2008 Apr 29.

37.

NFkappaB is persistently activated in continuously stimulated human neutrophils.

Miskolci V, Rollins J, Vu HY, Ghosh CC, Davidson D, Vancurova I.

Mol Med. 2007 Mar-Apr;13(3-4):134-42.

38.

Modulation of rat intestinal nuclear factor NF-kappaB by gum arabic.

Wapnir RA, Sherry B, Codipilly CN, Goodwin LO, Vancurova I.

Dig Dis Sci. 2008 Jan;53(1):80-7. Epub 2007 May 8.

PMID:
17486449
40.

TNFalpha release from peripheral blood leukocytes depends on a CRM1-mediated nuclear export.

Miskolci V, Ghosh CC, Rollins J, Romero C, Vu HY, Robinson S, Davidson D, Vancurova I.

Biochem Biophys Res Commun. 2006 Dec 15;351(2):354-60. Epub 2006 Oct 16.

PMID:
17064665
41.

Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway.

Hu M, Du Q, Vancurova I, Lin X, Miller EJ, Simms HH, Wang P.

Crit Care Med. 2005 Nov;33(11):2571-8.

PMID:
16276182
42.

NF-kappaB protects lung epithelium against hyperoxia-induced nonapoptotic cell death-oncosis.

Franek WR, Morrow DM, Zhu H, Vancurova I, Miskolci V, Darley-Usmar K, Simms HH, Mantell LL.

Free Radic Biol Med. 2004 Nov 15;37(10):1670-9.

PMID:
15477018
43.

Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils.

Miskolci V, Castro-Alcaraz S, Nguyen P, Vancura A, Davidson D, Vancurova I.

Arch Biochem Biophys. 2003 Sep 1;417(1):44-52.

PMID:
12921778
44.

Interleukin-10 inhibits proinflammatory chemokine release by neutrophils of the newborn without suppression of nuclear factor-kappa B.

Tryzmel J, Miskolci V, Castro-Alcaraz S, Vancurova I, Davidson D.

Pediatr Res. 2003 Sep;54(3):382-6. Epub 2003 Jun 4.

PMID:
12788980
45.

NF-kappa B regulation in human neutrophils by nuclear I kappa B alpha: correlation to apoptosis.

Castro-Alcaraz S, Miskolci V, Kalasapudi B, Davidson D, Vancurova I.

J Immunol. 2002 Oct 1;169(7):3947-53.

46.
47.

Zinc supplementation in oral rehydration solutions: experimental assessment and mechanisms of action.

Altaf W, Perveen S, Rehman KU, Teichberg S, Vancurova I, Harper RG, Wapnir RA.

J Am Coll Nutr. 2002 Feb;21(1):26-32.

PMID:
11838884
48.
49.
50.

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