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Items: 25


Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells.

Dosch AR, Dai X, Gaidarski Iii AA, Shi C, Castellanos JA, VanSaun MN, Merchant NB, Nagathihalli NS.

Oncotarget. 2019 Feb 1;10(10):1056-1069. doi: 10.18632/oncotarget.26621. eCollection 2019 Feb 1.


Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer.

Totiger TM, Srinivasan S, Jala VR, Lamichhane P, Dosch AR, Gaidarski AA 3rd, Joshi C, Rangappa S, Castellanos J, Vemula PK, Chen X, Kwon D, Kashikar N, VanSaun M, Merchant NB, Nagathihalli NS.

Mol Cancer Ther. 2019 Feb;18(2):301-311. doi: 10.1158/1535-7163.MCT-18-0464. Epub 2018 Nov 7.


Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer.

Srinivasan S, Totiger T, Shi C, Castellanos J, Lamichhane P, Dosch AR, Messaggio F, Kashikar N, Honnenahally K, Ban Y, Merchant NB, VanSaun M, Nagathihalli NS.

Cancer Res. 2018 Nov 1;78(21):6146-6158. doi: 10.1158/0008-5472.CAN-18-0579. Epub 2018 Sep 19.


Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.

Nagathihalli NS, Castellanos JA, Lamichhane P, Messaggio F, Shi C, Dai X, Rai P, Chen X, VanSaun MN, Merchant NB.

Cancer Res. 2018 Nov 1;78(21):6235-6246. doi: 10.1158/0008-5472.CAN-18-0634. Epub 2018 Aug 28.


Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth.

Messaggio F, Mendonsa AM, Castellanos J, Nagathihalli NS, Gorden L, Merchant NB, VanSaun MN.

Oncotarget. 2017 Aug 3;8(49):85378-85391. doi: 10.18632/oncotarget.19905. eCollection 2017 Oct 17.


Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells.

Nagathihalli NS, Castellanos JA, VanSaun MN, Dai X, Ambrose M, Guo Q, Xiong Y, Merchant NB.

Oncotarget. 2016 Oct 4;7(40):65982-65992. doi: 10.18632/oncotarget.11786.


Modulation of the leptin receptor mediates tumor growth and migration of pancreatic cancer cells.

Mendonsa AM, Chalfant MC, Gorden LD, VanSaun MN.

PLoS One. 2015 Apr 28;10(4):e0126686. doi: 10.1371/journal.pone.0126686. eCollection 2015.


Host and tumor derived MMP13 regulate extravasation and establishment of colorectal metastases in the liver.

Mendonsa AM, VanSaun MN, Ustione A, Piston DW, Fingleton BM, Gorden DL.

Mol Cancer. 2015 Feb 22;14:49. doi: 10.1186/s12943-014-0282-0.


New tools for the quantitative assessment of prodrug delivery and neurotoxicity.

Samuelson LE, Scherer RL, VanSaun MN, Fan KH, Dozier EA, Carter KJ, Koyama T, Shyr Y, Aschner M, Stanwood GD, Bornhop DJ, Matrisian LM, McIntyre JO.

Neurotoxicology. 2015 Mar;47:88-98. doi: 10.1016/j.neuro.2015.02.005. Epub 2015 Feb 27.


Hepatocellular proliferation correlates with inflammatory cell and cytokine changes in a murine model of nonalchoholic fatty liver disease.

Vansaun MN, Mendonsa AM, Lee Gorden D.

PLoS One. 2013 Sep 9;8(9):e73054. doi: 10.1371/journal.pone.0073054. eCollection 2013.


Targeting the Wnt pathway in synovial sarcoma models.

Barham W, Frump AL, Sherrill TP, Garcia CB, Saito-Diaz K, VanSaun MN, Fingleton B, Gleaves L, Orton D, Capecchi MR, Blackwell TS, Lee E, Yull F, Eid JE.

Cancer Discov. 2013 Nov;3(11):1286-301. doi: 10.1158/2159-8290.CD-13-0138. Epub 2013 Aug 6.


Molecular pathways: adiponectin and leptin signaling in cancer.

Vansaun MN.

Clin Cancer Res. 2013 Apr 15;19(8):1926-32. doi: 10.1158/1078-0432.CCR-12-0930. Epub 2013 Jan 25. Review.


Increased metastases are associated with inflammation and matrix metalloproteinase-9 activity at incision sites in a murine model of peritoneal dissemination of colorectal cancer.

Lee IK, Vansaun MN, Shim JH, Matrisian LM, Gorden DL.

J Surg Res. 2013 Apr;180(2):252-9. doi: 10.1016/j.jss.2012.04.074. Epub 2012 May 18.


Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2.

Garcia CB, Shaffer CM, Alfaro MP, Smith AL, Sun J, Zhao Z, Young PP, VanSaun MN, Eid JE.

Oncogene. 2012 May 3;31(18):2323-34. doi: 10.1038/onc.2011.418. Epub 2011 Sep 26.


Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model.

Gorden DL, Ivanova PT, Myers DS, McIntyre JO, VanSaun MN, Wright JK, Matrisian LM, Brown HA.

PLoS One. 2011;6(8):e22775. doi: 10.1371/journal.pone.0022775. Epub 2011 Aug 9.


High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model.

VanSaun MN, Lee IK, Washington MK, Matrisian L, Gorden DL.

Am J Pathol. 2009 Jul;175(1):355-64. doi: 10.2353/ajpath.2009.080703. Epub 2009 Jun 18.


Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon.

Scherer RL, VanSaun MN, McIntyre JO, Matrisian LM.

Mol Imaging. 2008 May-Jun;7(3):118-31.


Metastasis Research Society-American Association For Cancer Research Joint Conference on Metastasis.

Welch DR, Cooper CR, Hurst DR, Lynch CC, Martin MD, Vaidya KS, VanSaun MN, Mastro AM.

Cancer Res. 2008 Dec 1;68(23):9578-82. doi: 10.1158/0008-5472.CAN-08-3360. No abstract available.


Activation of Matrix Metalloproteinase-3 is altered at the frog neuromuscular junction following changes in synaptic activity.

VanSaun M, Humburg BC, Arnett MG, Pence M, Werle MJ.

Dev Neurobiol. 2007 Sep 15;67(11):1488-97.


Matrix metalloproteinases and cellular motility in development and disease.

VanSaun MN, Matrisian LM.

Birth Defects Res C Embryo Today. 2006 Mar;78(1):69-79. Review.


Regulation of the rapsyn promoter by kaiso and delta-catenin.

Rodova M, Kelly KF, VanSaun M, Daniel JM, Werle MJ.

Mol Cell Biol. 2004 Aug;24(16):7188-96.


Structural alterations at the neuromuscular junctions of matrix metalloproteinase 3 null mutant mice.

VanSaun M, Herrera AA, Werle MJ.

J Neurocytol. 2003 Nov;32(9):1129-42.


Activity dependent removal of agrin from synaptic basal lamina by matrix metalloproteinase 3.

Werle MJ, VanSaun M.

J Neurocytol. 2003 Jun-Sep;32(5-8):905-13. Review.


Matrix metalloproteinase-3 removes agrin from synaptic basal lamina

VanSaun M, Werle MJ.

J Neurobiol. 2000 Sep 5;44(3):369. No abstract available.


Matrix metalloproteinase-3 removes agrin from synaptic basal lamina.

VanSaun M, Werle MJ.

J Neurobiol. 2000 May;43(2):140-9. Erratum in: J Neurobiol 2000 Sep 5;44(3):369.


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