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Editorial: The Role of Myeloid-Derived Cells in the Progression of Liver Disease.

Korf H, Wiest R, Jalan R, van der Merwe S.

Front Immunol. 2019 Sep 18;10:2208. doi: 10.3389/fimmu.2019.02208. eCollection 2019. No abstract available.


Reversal of protein-losing enteropathy following surgical revision of a jejunal Roux-en-Y loop after liver transplantation: Look for lymphangiectasia!

Bronswijk M, Harlet R, Monbaliu D, Van der Merwe S, Pirenne J, Vanuytsels T.

Am J Transplant. 2019 Oct 2. doi: 10.1111/ajt.15630. [Epub ahead of print]


Combined versus single use 20 G fine-needle biopsy and 25 G fine-needle aspiration for endoscopic ultrasound-guided tissue sampling of solid gastrointestinal lesions.

van Riet PA, Giorgio Arcidiacono P, Petrone M, Quoc Nguyen N, Kitano M, Chang K, Larghi A, Iglesias-Garcia J, Giovannini M, van der Merwe S, Santo E, Baldaque-Silva F, Bucobo JC, Bruno MJ, Aslanian HR, Cahen DL, Farrell J.

Endoscopy. 2019 Jul 22. doi: 10.1055/a-0966-8755. [Epub ahead of print]


Agreement on endoscopic ultrasonography-guided tissue specimens: Comparing a 20-G fine-needle biopsy to a 25-G fine-needle aspiration needle among academic and non-academic pathologists.

van Riet PA, Cahen DL, Biermann K, Hansen B, Larghi A, Rindi G, Fellegara G, Arcidiacono P, Doglioni C, Liberta Decarli N, Iglesias-Garcia J, Abdulkader I, Lazare Iglesias H, Kitano M, Chikugo T, Yasukawa S, van der Valk H, Nguyen NQ, Ruszkiewicz A, Giovannini M, Poizat F, van der Merwe S, Roskams T, Santo E, Marmor S, Chang K, Lin F, Farrell J, Robert M, Bucobo JC, Heimann A, Baldaque-Silva F, Fernández Moro C, Bruno MJ.

Dig Endosc. 2019 Jul 10. doi: 10.1111/den.13424. [Epub ahead of print]


Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses.

Vieira-Silva S, Sabino J, Valles-Colomer M, Falony G, Kathagen G, Caenepeel C, Cleynen I, van der Merwe S, Vermeire S, Raes J.

Nat Microbiol. 2019 Jun 17. doi: 10.1038/s41564-019-0483-9. [Epub ahead of print]


Macrophages as Key Players during Adipose Tissue-Liver Crosstalk in Nonalcoholic Fatty Liver Disease.

Korf H, Boesch M, Meelberghs L, van der Merwe S.

Semin Liver Dis. 2019 Jul;39(3):291-300. doi: 10.1055/s-0039-1687851. Epub 2019 Apr 30.


Age Matching of Elderly Liver Grafts With Elderly Recipients Does Not Have a Synergistic Effect on Long-term Outcomes When Both Are Carefully Selected.

Gilbo N, Jochmans I, Sainz-Barriga M, Nevens F, van der Merwe S, Laleman W, Verslype C, Cassiman D, Verbeke L, van Malenstein H, Roskams T, Pirenne J, Monbaliu D.

Transplant Direct. 2019 Mar 26;5(4):e342. doi: 10.1097/TXD.0000000000000883. eCollection 2019 Apr.


Reply to: "Outcome of critically ill cirrhotic patients admitted to the ICU: The role of ACLF".

van der Merwe S, Laleman W, Langouche L, Meersseman P.

J Hepatol. 2019 Apr;70(4):804-805. doi: 10.1016/j.jhep.2019.01.001. Epub 2019 Jan 23. No abstract available.


Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.

Balemans D, Aguilera-Lizarraga J, Florens MV, Jain P, Denadai-Souza A, Viola MF, Alpizar YA, Van Der Merwe S, Vanden Berghe P, Talavera K, Vanner S, Wouters MM, Boeckxstaens GE.

Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G338-G349. doi: 10.1152/ajpgi.00116.2018. Epub 2019 Jan 10.


Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity.

Korf H, du Plessis J, van Pelt J, De Groote S, Cassiman D, Verbeke L, Ghesquière B, Fendt SM, Bird MJ, Talebi A, Van Haele M, Feio-Azevedo R, Meelberghs L, Roskams T, Mookerjee RP, Mehta G, Jalan R, Gustot T, Laleman W, Nevens F, van der Merwe SW.

Gut. 2019 Oct;68(10):1872-1883. doi: 10.1136/gutjnl-2018-316888. Epub 2018 Dec 22.


Engineering and Development of Chitosan-Based Nanocoatings for Ocular Contact Lenses.

Mehta P, Al-Kinani AA, Arshad MS, Singh N, van der Merwe SM, Chang MW, Alany RG, Ahmad Z.

J Pharm Sci. 2019 Apr;108(4):1540-1551. doi: 10.1016/j.xphs.2018.11.036. Epub 2018 Dec 1.


Biliary papillomatosis.

Struyve M, Van Der Merwe S.

Dig Endosc. 2019 Mar;31(2):209. doi: 10.1111/den.13299. Epub 2018 Dec 25. No abstract available.


A multicenter randomized trial comparing a 25-gauge EUS fine-needle aspiration device with a 20-gauge EUS fine-needle biopsy device.

van Riet PA, Larghi A, Attili F, Rindi G, Nguyen NQ, Ruszkiewicz A, Kitano M, Chikugo T, Aslanian H, Farrell J, Robert M, Adeniran A, Van Der Merwe S, Roskams T, Chang K, Lin F, Lee JG, Arcidiacono PG, Petrone M, Doglioni C, Iglesias-Garcia J, Abdulkader I, Giovannini M, Bories E, Poizat F, Santo E, Scapa E, Marmor S, Bucobo JC, Buscaglia JM, Heimann A, Wu M, Baldaque-Silva F, Moro CF, Erler NS, Biermann K, Poley JW, Cahen DL, Bruno MJ.

Gastrointest Endosc. 2019 Feb;89(2):329-339. doi: 10.1016/j.gie.2018.10.026. Epub 2018 Oct 24.


Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough.

Laleman W, Claria J, Van der Merwe S, Moreau R, Trebicka J.

Can J Gastroenterol Hepatol. 2018 Aug 1;2018:1027152. doi: 10.1155/2018/1027152. eCollection 2018. Review.


Thrombosis of a portal vein aneurysm: a case report with literature review.

De Vloo C, Matton T, Meersseman W, Maleux G, Houthoofd S, Op de Beeck K, Laleman W, Van Malenstein H, Nevens F, Verbeke L, Van der Merwe S, Verslype C.

Acta Clin Belg. 2019 Apr;74(2):115-120. doi: 10.1080/17843286.2018.1511298. Epub 2018 Aug 27. Review.


At similar weight loss, dietary composition determines the degree of glycemic improvement in diet-induced obese C57BL/6 mice.

Vangoitsenhoven R, van der Ende M, Corbeels K, Monteiro Carvalho Mori Cunha JP, Lannoo M, Bedossa P, van der Merwe S, Mertens A, Gesquiere I, Meulemans A, Matthys C, Mathieu C, Overbergh L, Van der Schueren B.

PLoS One. 2018 Jul 23;13(7):e0200779. doi: 10.1371/journal.pone.0200779. eCollection 2018.


No Superiority of Stents vs Balloon Dilatation for Dominant Strictures in Patients With Primary Sclerosing Cholangitis.

Ponsioen CY, Arnelo U, Bergquist A, Rauws EA, Paulsen V, Cantú P, Parzanese I, De Vries EM, van Munster KN, Said K, Chazouillères O, Desaint B, Kemgang A, Färkkilä M, Van der Merwe S, Van Steenbergen W, Marschall HU, Stotzer PO, Thorburn D, Pereira SP, Aabakken L.

Gastroenterology. 2018 Sep;155(3):752-759.e5. doi: 10.1053/j.gastro.2018.05.034. Epub 2018 May 24.


Improved survival after LTx-associated acute GVHD with mAb therapy targeting IL2RAb and soluble TNFAb: Single-center experience and systematic review.

Minnee RC, Fieuws S, Jochmans I, Aerts R, Sainz Barriga M, Debaveye Y, Maertens J, Vandenberghe P, Laleman W, van der Merwe S, Verslype C, Cassiman D, Ferdinande P, Nevens F, Pirenne J, Monbaliu D.

Am J Transplant. 2018 Dec;18(12):3007-3020. doi: 10.1111/ajt.14923. Epub 2018 Jun 23.


The intensive care unit course and outcome in acute-on-chronic liver failure are comparable to other populations.

Meersseman P, Langouche L, du Plessis J, Korf H, Mekeirele M, Laleman W, Nevens F, Wilmer A, Van den Berghe G, van der Merwe SW.

J Hepatol. 2018 Oct;69(4):803-809. doi: 10.1016/j.jhep.2018.04.025. Epub 2018 May 4.


Personalized subcutaneous administration of hepatitis B surface antibodies without nucleos(t)ide analogs for patients at risk of renal failure after liver transplantation: a prospective single center cohort study.

Bielen R, Robaeys G, Schelfhout S, Monbaliu D, Van der Merwe S, Pirenne J, Nevens F.

Transpl Int. 2018 May;31(5):503-509. doi: 10.1111/tri.13112. Epub 2018 Feb 2.


Nutritional supplements for people being treated for active tuberculosis: A technical summary.

Grobler L, Durao S, Van der Merwe SM, Wessels J, Naude CE.

S Afr Med J. 2017 Dec 13;108(1):16-18. doi: 10.7196/SAMJ.2017.v108i1.12839.


The economic impact of using single-operator cholangioscopy for the treatment of difficult bile duct stones and diagnosis of indeterminate bile duct strictures.

Deprez PH, Garces Duran R, Moreels T, Furneri G, Demma F, Verbeke L, Van der Merwe SW, Laleman W.

Endoscopy. 2018 Feb;50(2):109-118. doi: 10.1055/s-0043-121268. Epub 2017 Nov 24.


Pre-operative trans-catheter arterial chemo-embolization increases hepatic artery thrombosis after liver transplantation - a retrospective study.

Gilbo N, Van Praet L, Jochmans I, Sainz-Barriga M, Verslype C, Maleux G, Laleman W, van der Merwe S, Cassiman D, Nevens F, Monbaliu D, Pirenne J.

Transpl Int. 2018 Jan;31(1):71-81. doi: 10.1111/tri.13046. Epub 2017 Sep 12.


A biodegradable non-covered self-expandable stent to treat pancreatic duct strictures in chronic pancreatitis: a proof of principle.

Cahen DL, van der Merwe SW, Laleman W, Poley JW, Bruno MJ.

Gastrointest Endosc. 2018 Feb;87(2):486-491. doi: 10.1016/j.gie.2017.08.018. Epub 2017 Aug 24.


Ethyl Glucuronide in Hair Is an Accurate Biomarker of Chronic Excessive Alcohol Use in Patients With Alcoholic Cirrhosis.

Verbeek J, Crunelle CL, Leurquin-Sterk G, Michielsen PP, De Doncker M, Monbaliu D, Pirenne J, Roskams T, van der Merwe S, Cassiman D, Neels H, Nevens F.

Clin Gastroenterol Hepatol. 2018 Mar;16(3):454-456. doi: 10.1016/j.cgh.2017.08.019. Epub 2017 Aug 19. No abstract available.


A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study.

Laleman W, van der Merwe S, Verbeke L, Vanbeckevoort D, Aerts R, Prenen H, Van Cutsem E, Verslype C.

Endoscopy. 2017 Oct;49(10):977-982. doi: 10.1055/s-0043-113559. Epub 2017 Jul 21.


Adipose-derived exosomal MicroRNAs orchestrate gene regulation in the liver: Is this the missing link in nonalcoholic fatty liver disease?

Korf H, van der Merwe S.

Hepatology. 2017 Nov;66(5):1689-1691. doi: 10.1002/hep.29343. Epub 2017 Sep 29. No abstract available.


Accountable or not accountable: A profile comparison of alleged offenders referred to the Free State Psychiatric Complex Forensic Observation Ward in Bloemfontein from 2009 to 2012.

du Plessis ED, du Plessis HJ, Nel HC, Oosthuizen I, van der Merwe S, Zwiegers S, Joubert G.

S Afr J Psychiatr. 2017 May 31;23:1054. doi: 10.4102/sajpsychiatry.v23i0.1054. eCollection 2017.


Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice.

Verbeek J, Spincemaille P, Vanhorebeek I, Van den Berghe G, Vander Elst I, Windmolders P, van Pelt J, van der Merwe S, Bedossa P, Nevens F, Cammue B, Thevissen K, Cassiman D.

Lipids Health Dis. 2017 Feb 23;16(1):46. doi: 10.1186/s12944-017-0432-7.


EUS-guided biliary drainage or enteroscopy-assisted ERCP in patients with surgical anatomy and biliary obstruction: an international comparative study.

Khashab MA, El Zein MH, Sharzehi K, Marson FP, Haluszka O, Small AJ, Nakai Y, Park DH, Kunda R, Teoh AY, Peñas I, Perez-Miranda M, Kumbhari V, Van der Merwe S, Artifon EL, Ross AS.

Endosc Int Open. 2016 Dec;4(12):E1322-E1327. Epub 2016 Aug 30.


Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD.

du Plessis J, Korf H, van Pelt J, Windmolders P, Vander Elst I, Verrijken A, Hubens G, Van Gaal L, Cassiman D, Nevens F, Francque S, van der Merwe S.

PLoS One. 2016 Dec 19;11(12):e0166048. doi: 10.1371/journal.pone.0166048. eCollection 2016.


Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study.

Hermans E, Van der Merwe SW, Depreeuw J, Dekervel J, Radaelli E, Roskams T, van Pelt Jos J, Topal B, Verslype C, Prenen H, Van Steenbergen W, Nevens F, Lambrechts D, Amant F.

Endoscopy. 2016 Nov;48(11):1016-1022. Epub 2016 Sep 14.


 Percutaneous shunt reduction for the management of TIPS-induced acute liver decompensation: A follow-up study.

De Keyzer B, Nevens F, Laenen A, Heye S, Laleman W, Verslype C, van der Merwe S, Maleux G.

Ann Hepatol. 2016 Nov-Dec 2016;15(6):911-917.


Pharmaceutical and biomaterial engineering via electrohydrodynamic atomization technologies.

Mehta P, Haj-Ahmad R, Rasekh M, Arshad MS, Smith A, van der Merwe SM, Li X, Chang MW, Ahmad Z.

Drug Discov Today. 2017 Jan;22(1):157-165. doi: 10.1016/j.drudis.2016.09.021. Epub 2016 Sep 28. Review.


Expanded polytetrafluoroethylene-covered stent-grafts for transjugular intrahepatic portosystemic shunts in cirrhotic patients: Long-term patency and clinical outcome results.

Geeroms B, Laleman W, Laenen A, Heye S, Verslype C, van der Merwe S, Nevens F, Maleux G.

Eur Radiol. 2017 May;27(5):1795-1803. doi: 10.1007/s00330-016-4570-5. Epub 2016 Sep 15.


Usefulness of the single-operator cholangioscopy system SpyGlass in biliary disease: a single-center prospective cohort study and aggregated review.

Laleman W, Verraes K, Van Steenbergen W, Cassiman D, Nevens F, Van der Merwe S, Verslype C.

Surg Endosc. 2017 May;31(5):2223-2232. doi: 10.1007/s00464-016-5221-2. Epub 2016 Sep 7. Review.


Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD.

Sabino J, Vieira-Silva S, Machiels K, Joossens M, Falony G, Ballet V, Ferrante M, Van Assche G, Van der Merwe S, Vermeire S, Raes J.

Gut. 2016 Oct;65(10):1681-9. doi: 10.1136/gutjnl-2015-311004. Epub 2016 May 20.


Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.

Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD.

Gut. 2017 Apr;66(4):620-632. doi: 10.1136/gutjnl-2015-310904. Epub 2016 May 5.


Prospective international multicenter study on endoscopic ultrasound-guided biliary drainage for patients with malignant distal biliary obstruction after failed endoscopic retrograde cholangiopancreatography.

Khashab MA, Van der Merwe S, Kunda R, El Zein MH, Teoh AY, Marson FP, Fabbri C, Tarantino I, Varadarajulu S, Modayil RJ, Stavropoulos SN, Peñas I, Ngamruengphong S, Kumbhari V, Romagnuolo J, Shah R, Kalloo AN, Perez-Miranda M, Artifon EL.

Endosc Int Open. 2016 Apr;4(4):E487-96. doi: 10.1055/s-0042-102648. Epub 2016 Mar 30.


Ex vivo buccal drug delivery of ropinirole hydrochloride in the presence of permeation enhancers: the effect of charge.

Kontogiannidou E, Andreadis DA, Zografos AL, Nazar H, Klepetsanis P, van der Merwe SM, Fatouros DG.

Pharm Dev Technol. 2017 Dec;22(8):1017-1021. doi: 10.3109/10837450.2015.1135343. Epub 2016 Jan 21.


Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome.

Wouters MM, Balemans D, Van Wanrooy S, Dooley J, Cibert-Goton V, Alpizar YA, Valdez-Morales EE, Nasser Y, Van Veldhoven PP, Vanbrabant W, Van der Merwe S, Mols R, Ghesquière B, Cirillo C, Kortekaas I, Carmeliet P, Peetermans WE, Vermeire S, Rutgeerts P, Augustijns P, Hellings PW, Belmans A, Vanner S, Bulmer DC, Talavera K, Vanden Berghe P, Liston A, Boeckxstaens GE.

Gastroenterology. 2016 Apr;150(4):875-87.e9. doi: 10.1053/j.gastro.2015.12.034. Epub 2016 Jan 2.


Percutaneous shunt reduction for the management of TIPS-induced acute liver decompensation: A follow-up study.

De Keyzer B, Nevens F, Laenen A, Heye S, Laleman W, Verslype C, van der Merwe S, Maleux G.

Ann Hepatol. 2016 Nov - Dec;15(6):911-917. doi: 10.5604/16652681.1222110.


CD14(+) macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide.

Cassol E, Rossouw T, Malfeld S, Mahasha P, Slavik T, Seebregts C, Bond R, du Plessis J, Janssen C, Roskams T, Nevens F, Alfano M, Poli G, van der Merwe SW.

BMC Infect Dis. 2015 Oct 17;15:430. doi: 10.1186/s12879-015-1176-5.


Budd-Chiari syndrome: reassessment of a step-wise treatment strategy.

Martens P, Maleux GA, Devos T, Monbaliu D, Heye S, Verslype C, Laleman W, Cassiman D, Van der Merwe SW, Van Steenbergen W, Jochmans I, Aerts R, Pirenne J, Nevens F.

Acta Gastroenterol Belg. 2015 Jul-Sep;78(3):299-305.


A combination of molecular markers and clinical features improve the classification of pancreatic cysts.

Springer S, Wang Y, Dal Molin M, Masica DL, Jiao Y, Kinde I, Blackford A, Raman SP, Wolfgang CL, Tomita T, Niknafs N, Douville C, Ptak J, Dobbyn L, Allen PJ, Klimstra DS, Schattner MA, Schmidt CM, Yip-Schneider M, Cummings OW, Brand RE, Zeh HJ, Singhi AD, Scarpa A, Salvia R, Malleo G, Zamboni G, Falconi M, Jang JY, Kim SW, Kwon W, Hong SM, Song KB, Kim SC, Swan N, Murphy J, Geoghegan J, Brugge W, Fernandez-Del Castillo C, Mino-Kenudson M, Schulick R, Edil BH, Adsay V, Paulino J, van Hooft J, Yachida S, Nara S, Hiraoka N, Yamao K, Hijioka S, van der Merwe S, Goggins M, Canto MI, Ahuja N, Hirose K, Makary M, Weiss MJ, Cameron J, Pittman M, Eshleman JR, Diaz LA Jr, Papadopoulos N, Kinzler KW, Karchin R, Hruban RH, Vogelstein B, Lennon AM.

Gastroenterology. 2015 Nov;149(6):1501-10. doi: 10.1053/j.gastro.2015.07.041. Epub 2015 Aug 4.


Electrohydrodynamic Preparation of Nanomedicines.

Rasekh M, Smith A, Arshad MS, Gunduz O, Van der Merwe SM, Smith G, Ahmad Z.

Curr Top Med Chem. 2015;15(22):2316-27. Review.


Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease.

du Plessis J, van Pelt J, Korf H, Mathieu C, van der Schueren B, Lannoo M, Oyen T, Topal B, Fetter G, Nayler S, van der Merwe T, Windmolders P, Van Gaal L, Verrijken A, Hubens G, Gericke M, Cassiman D, Francque S, Nevens F, van der Merwe S.

Gastroenterology. 2015 Sep;149(3):635-48.e14. doi: 10.1053/j.gastro.2015.05.044. Epub 2015 May 28.


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