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Items: 1 to 50 of 161

1.

Enhanced nucleotide excision repair in human fibroblasts pre-exposed to ionizing radiation.

Cramers P, Filon AR, Pines A, Kleinjans JC, Mullenders LH, van Zeeland AA.

Photochem Photobiol. 2012 Jan-Feb;88(1):147-53. doi: 10.1111/j.1751-1097.2011.01019.x. Epub 2011 Nov 17.

PMID:
22017241
2.

Impaired repair of ionizing radiation-induced DNA damage in Cockayne syndrome cells.

Cramers P, Verhoeven EE, Filon AR, Rockx DA, Santos SJ, van der Leer AA, Kleinjans JC, van Zeeland AA, Mullenders LH.

Radiat Res. 2011 Apr;175(4):432-43. doi: 10.1667/RR1972.1. Epub 2011 Feb 7.

PMID:
21299404
3.

Replication protein A safeguards genome integrity by controlling NER incision events.

Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, van Zeeland AA, Mullenders LH, Fousteri M.

J Cell Biol. 2011 Feb 7;192(3):401-15. doi: 10.1083/jcb.201006011. Epub 2011 Jan 31.

4.

Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra.

Vreeswijk MP, Meijers CM, Giphart-Gassler M, Vrieling H, van Zeeland AA, Mullenders LH, Loenen WA.

Mutat Res. 2009 Apr 26;663(1-2):7-14. doi: 10.1016/j.mrfmmm.2008.12.007. Epub 2008 Dec 27.

PMID:
19150617
5.

Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea.

van Zeeland AA, de Groot AJ, Mohn GR, van Steeg H, van Oostrom C, van Duijn-Goedhart AM, Mullenders LF, Jansen JG.

Mutat Res. 2008 Apr 2;640(1-2):131-8. doi: 10.1016/j.mrfmmm.2007.12.011. Epub 2007 Dec 31.

PMID:
18249417
6.

Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures.

de Vries FA, Zonneveld JB, de Groot AJ, Koning RI, van Zeeland AA, Pastink A.

Mutat Res. 2007 Feb 3;615(1-2):143-52. Epub 2006 Dec 16.

PMID:
17208257
7.
8.

Pre-exposure to low doses: modulation of X-ray-induced dna damage and repair?

Cramers P, Atanasova P, Vrolijk H, Darroudi F, van Zeeland AA, Huiskamp R, Mullenders LH, Kleinjans JC.

Radiat Res. 2005 Oct;164(4 Pt 1):383-90.

PMID:
16187740
9.

Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe.

de Vries FA, Zonneveld JB, van Duijn-Goedhart A, Roodbergen M, Boei J, van Buul PP, Essers J, van Steeg H, van Zeeland AA, van Benthem J, Pastink A.

DNA Repair (Amst). 2005 Sep 28;4(10):1121-8.

PMID:
16009599
10.

Transcription-coupled repair: impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors.

van Zeeland AA, Vreeswijk MP, de Gruijl FR, van Kranen HJ, Vrieling H, Mullenders LF.

Mutat Res. 2005 Sep 4;577(1-2):170-8. Review.

PMID:
15949822
11.

Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation.

de Vries FA, de Boer E, van den Bosch M, Baarends WM, Ooms M, Yuan L, Liu JG, van Zeeland AA, Heyting C, Pastink A.

Genes Dev. 2005 Jun 1;19(11):1376-89.

12.

The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions.

Moser J, Volker M, Kool H, Alekseev S, Vrieling H, Yasui A, van Zeeland AA, Mullenders LH.

DNA Repair (Amst). 2005 May 2;4(5):571-82.

PMID:
15811629
13.

Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation.

Boerma M, van der Wees CG, Vrieling H, Svensson JP, Wondergem J, van der Laarse A, Mullenders LH, van Zeeland AA.

BMC Genomics. 2005 Jan 18;6:6.

14.

Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts.

Riou L, Eveno E, van Hoffen A, van Zeeland AA, Sarasin A, Mullenders LH.

Cancer Res. 2004 Feb 1;64(3):889-94.

15.

Deficient global genome repair of UV-induced cyclobutane pyrimidine dimers in terminally differentiated myocytes and proliferating fibroblasts from the rat heart.

van der Wees CG, Vreeswijk MP, Persoon M, van der Laarse A, van Zeeland AA, Mullenders LH.

DNA Repair (Amst). 2003 Dec 9;2(12):1297-308.

PMID:
14642560
16.

Nucleotide excision repair and its interplay with transcription.

van Hoffen A, Balajee AS, van Zeeland AA, Mullenders LH.

Toxicology. 2003 Nov 15;193(1-2):79-90. Review.

PMID:
14599769
17.

Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions.

Rademakers S, Volker M, Hoogstraten D, Nigg AL, Moné MJ, Van Zeeland AA, Hoeijmakers JH, Houtsmuller AB, Vermeulen W.

Mol Cell Biol. 2003 Aug;23(16):5755-67.

18.

32nd annual meeting of European Environmental Mutagen Society. DNA damage and repair fundamental aspects and contribution to human disorders.

Tudek B, Ciesla Z, Janion C, Boiteux S, Bebenek K, Shinagawa H, Bartsch H, Laval J, van Zeeland AA, Mullenders LF, Szyfter K, Collins A, Kruszewski M.

DNA Repair (Amst). 2003 Jun 11;2(6):765-81. No abstract available.

PMID:
12767355
19.

Separation of neonatal rat ventricular myocytes and non-myocytes by centrifugal elutriation.

Boerma M, van der Wees CG, Wondergem J, van der Laarse A, Persoon M, van Zeeland AA, Mullenders LH.

Pflugers Arch. 2002 Jun;444(3):452-6. Epub 2002 Apr 4.

PMID:
12111256
20.

Local UV-induced DNA damage in cell nuclei results in local transcription inhibition.

Moné MJ, Volker M, Nikaido O, Mullenders LH, van Zeeland AA, Verschure PJ, Manders EM, van Driel R.

EMBO Rep. 2001 Nov;2(11):1013-7.

21.

Effect of cigarette smoke exposure on the modulation of 8-oxo-2'-deoxyguanosine in rat lungs as analyzed by 32P-postlabeling and HPLC-ECD.

Arif JM, Vadhanam MV, De Groot AJ, Van Zeeland AA, Gairola CG, Gupta RC.

Int J Oncol. 2001 Oct;19(4):763-6.

PMID:
11562752
22.

Sequential assembly of the nucleotide excision repair factors in vivo.

Volker M, Moné MJ, Karmakar P, van Hoffen A, Schul W, Vermeulen W, Hoeijmakers JH, van Driel R, van Zeeland AA, Mullenders LH.

Mol Cell. 2001 Jul;8(1):213-24.

23.

DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice.

Wijnhoven SW, Kool HJ, Mullenders LH, Slater R, van Zeeland AA, Vrieling H.

Carcinogenesis. 2001 Jul;22(7):1099-106.

PMID:
11408355
24.

Gene and sequence specificity of DNA damage induction and repair: consequences for mutagenesis.

van Zeeland AA, Mullenders LH, Vrieling H.

Mutat Res. 2001 Feb 25;485(1):15-21. Review.

PMID:
11341990
25.

Loss of heterozygosity in somatic cells of the mouse. An important step in cancer initiation?

Wijnhoven SW, Kool HJ, van Teijlingen CM, van Zeeland AA, Vrieling H.

Mutat Res. 2001 Jan 25;473(1):23-36. Review.

PMID:
11166024
26.

The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice.

Wijnhoven SW, Kool HJ, van Oostrom CT, Beems RB, Mullenders LH, van Zeeland AA, van der Horst GT, Vrieling H, van Steeg H.

Cancer Res. 2000 Oct 15;60(20):5681-7.

27.

Age-dependent spontaneous mutagenesis in Xpc mice defective in nucleotide excision repair.

Wijnhoven SW, Kool HJ, Mullenders LH, van Zeeland AA, Friedberg EC, van der Horst GT, van Steeg H, Vrieling H.

Oncogene. 2000 Oct 12;19(43):5034-7.

28.

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis.

van Oosten M, Rebel H, Friedberg EC, van Steeg H, van der Horst GT, van Kranen HJ, Westerman A, van Zeeland AA, Mullenders LH, de Gruijl FR.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11268-73.

29.

UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II.

Rockx DA, Mason R, van Hoffen A, Barton MC, Citterio E, Bregman DB, van Zeeland AA, Vrieling H, Mullenders LH.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10503-8.

30.

The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.

Van Sloun PP, Jansen JG, Weeda G, Mullenders LH, van Zeeland AA, Lohman PH, Vrieling H.

Nucleic Acids Res. 1999 Aug 15;27(16):3276-82.

31.

Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.

van Hoffen A, Kalle WH, de Jong-Versteeg A, Lehmann AR, van Zeeland AA, Mullenders LH.

Nucleic Acids Res. 1999 Jul 15;27(14):2898-904.

32.

Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo.

Bol SA, van Steeg H, van Oostrom CT, Tates AD, Vrieling H, de Groot AJ, Mullenders LH, van Zeeland AA, Jansen JG.

Mutagenesis. 1999 May;14(3):317-22.

PMID:
10374999
33.

Mutation in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens.

van Zeeland AA, Vrieling H.

IARC Sci Publ. 1999;(146):355-65. Review. No abstract available.

PMID:
10353394
34.
35.
36.

Postgraduate studies in radiation biology in Europe.

Trott KR, Lohmann PH, Natarajan AT, van Zeeland AA, Schibilla H, Chadwick K, Kellerer AM, Steinhäusler F.

Radiat Environ Biophys. 1998 Oct;37(3):139-42.

PMID:
9840481
37.

Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouse.

Wijnhoven SW, Van Sloun PP, Kool HJ, Weeda G, Slater R, Lohman PH, van Zeeland AA, Vrieling H.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13759-64.

38.

Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers.

Vreeswijk MP, Overkamp MW, Westland BE, van Hees-Stuivenberg S, Vrieling H, Zdzienicka MZ, van Zeeland AA, Mullenders LH.

Mutat Res. 1998 Oct 21;409(1):49-56.

PMID:
9806502
39.

Determination of spontaneous loss of heterozygosity mutations in Aprt heterozygous mice.

Van Sloun PP, Wijnhoven SW, Kool HJ, Slater R, Weeda G, van Zeeland AA, Lohman PH, Vrieling H.

Nucleic Acids Res. 1998 Nov 1;26(21):4888-94.

40.

Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.

Elder RH, Jansen JG, Weeks RJ, Willington MA, Deans B, Watson AJ, Mynett KJ, Bailey JA, Cooper DP, Rafferty JA, Heeran MC, Wijnhoven SW, van Zeeland AA, Margison GP.

Mol Cell Biol. 1998 Oct;18(10):5828-37.

41.

UV-induced alterations in the spatial distribution of the basal transcription factor TFIIH: an early event in nucleotide excision repair.

Karmarkar P, Leer-van Hoffen A, Natarajan AT, van Zeeland AA, Mullenders LH.

Mutat Res. 1998 Aug 3;404(1-2):129-31.

PMID:
9729332
42.

Transcription coupled repair and its impact on mutagenesis.

Vrieling H, van Zeeland AA, Mullenders LH.

Mutat Res. 1998 May 25;400(1-2):135-42. Review. No abstract available.

PMID:
9685614
43.

Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.

Bol SA, van Steeg H, Jansen JG, Van Oostrom C, de Vries A, de Groot AJ, Tates AD, Vrieling H, van Zeeland AA, Mullenders LH.

Cancer Res. 1998 Jul 1;58(13):2850-6.

44.

Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes.

Abrahams PJ, Houweling A, Cornelissen-Steijger PD, Jaspers NG, Darroudi F, Meijers CM, Mullenders LH, Filon R, Arwert F, Pinedo HM, Natarajan AP, Terleth C, Van Zeeland AA, van der Eb AJ.

Mutat Res. 1998 Mar;407(2):189-201.

PMID:
9637247
45.
46.

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

Op het Veld CW, Jansen J, Zdzienicka MZ, Vrieling H, van Zeeland AA.

Mutat Res. 1998 Feb 26;398(1-2):83-92.

PMID:
9626968
47.

Lack of transcription-coupled repair of acetylaminofluorene DNA adducts in human fibroblasts contrasts their efficient inhibition of transcription.

van Oosterwijk MF, Filon R, de Groot AJ, van Zeeland AA, Mullenders LH.

J Biol Chem. 1998 May 29;273(22):13599-604.

48.

Impairment of nucleotide excision repair by apoptosis in UV-irradiated mouse cells.

Vreeswijk MP, Westland BE, Hess MT, Naegeli H, Vrieling H, van Zeeland AA, Mullenders LH.

Cancer Res. 1998 May 1;58(9):1978-85.

49.

Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents.

Op het Veld CW, van Hees-Stuivenberg S, van Zeeland AA, Jansen JG.

Mutagenesis. 1997 Nov;12(6):417-24.

PMID:
9412994
50.

DNA repair of UV photoproducts and mutagenesis in human mitochondrial DNA.

Pascucci B, Versteegh A, van Hoffen A, van Zeeland AA, Mullenders LH, Dogliotti E.

J Mol Biol. 1997 Oct 24;273(2):417-27.

PMID:
9344749

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