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Items: 41


Two Cases of Newly Characterized Neisseria Species, Brazil.

Mustapha MM, Lemos APS, Griffith MP, Evans DR, Marx R, Coltro ESF, Siebra CA, Timm L, Ribeiro H, Monteiro A, Pasculle AW, Marsh JW, Van Tyne D, Harrison LH, Sacchi CT.

Emerg Infect Dis. 2020 Feb;26(2):366-369. doi: 10.3201/eid2602.190191.


A mutation in the glycosyltransferase gene lafB causes daptomycin hypersusceptibility in Enterococcus faecium.

Mello SS, Van Tyne D, Lebreton F, Silva SQ, Nogueira MCL, Gilmore MS, Camargo ILBC.

J Antimicrob Chemother. 2020 Jan 1;75(1):36-45. doi: 10.1093/jac/dkz403.


Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae ST258 at a Tertiary Care Hospital over 8 Years.

Marsh JW, Mustapha MM, Griffith MP, Evans DR, Ezeonwuka C, Pasculle AW, Shutt KA, Sundermann A, Ayres AM, Shields RK, Babiker A, Cooper VS, Van Tyne D, Harrison LH.

mBio. 2019 Sep 3;10(5). pii: e01945-19. doi: 10.1128/mBio.01945-19.


Chicken Meat-Associated Enterococci: Influence of Agricultural Antibiotic Use and Connection to the Clinic.

Manson AL, Van Tyne D, Straub TJ, Clock S, Crupain M, Rangan U, Gilmore MS, Earl AM.

Appl Environ Microbiol. 2019 Oct 30;85(22). pii: e01559-19. doi: 10.1128/AEM.01559-19. Print 2019 Nov 15.


Patient-to-Patient Transmission of Klebsiella pneumoniae Carbapenemase Variants with Reduced Ceftazidime-Avibactam Susceptibility.

Munoz-Price LS, Reeme AE, Buchan BW, Mettus RT, Mustapha MM, Van Tyne D, Shields RK, Doi Y.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00955-19. doi: 10.1128/AAC.00955-19. Print 2019 Oct.


Outbreak of Vancomycin-resistant Enterococcus faecium in Interventional Radiology: Detection Through Whole Genome Sequencing-Based Surveillance.

Sundermann AJ, Babiker A, Marsh JW, Shutt KA, Mustapha MM, Pasculle AW, Ezeonwuka C, Saul MI, Pacey MP, Van Tyne D, Ayres AM, Cooper VS, Snyder GM, Harrison LH.

Clin Infect Dis. 2019 Jul 16. pii: ciz666. doi: 10.1093/cid/ciz666. [Epub ahead of print]


Pathogenicity of Enterococci.

Fiore E, Van Tyne D, Gilmore MS.

Microbiol Spectr. 2019 Jul;7(4). doi: 10.1128/microbiolspec.GPP3-0053-2018.


Reduced ceftazidime and ertapenem susceptibility due to production of OXA-2 in Klebsiella pneumoniae ST258.

Iovleva A, Mettus RT, McElheny CL, Mustapha MM, Van Tyne D, Shields RK, Pasculle AW, Cooper VS, Doi Y.

J Antimicrob Chemother. 2019 Aug 1;74(8):2203-2208. doi: 10.1093/jac/dkz183.


Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream.

Van Tyne D, Manson AL, Huycke MM, Karanicolas J, Earl AM, Gilmore MS.

Sci Transl Med. 2019 Apr 10;11(487). pii: eaat8418. doi: 10.1126/scitranslmed.aat8418.


Staphylococcus aureus from ocular and otolaryngology infections are frequently resistant to clinically important antibiotics and are associated with lineages of community and hospital origins.

Wurster JI, Bispo PJM, Van Tyne D, Cadorette JJ, Boody R, Gilmore MS.

PLoS One. 2018 Dec 6;13(12):e0208518. doi: 10.1371/journal.pone.0208518. eCollection 2018.


Molecular basis for the emergence of a new hospital endemic tigecycline-resistant Enterococcus faecalis ST103 lineage.

Dabul ANG, Avaca-Crusca JS, Navais RB, Merlo TP, Van Tyne D, Gilmore MS, Camargo ILBDC.

Infect Genet Evol. 2019 Jan;67:23-32. doi: 10.1016/j.meegid.2018.10.018. Epub 2018 Oct 25.


Long-Term Colonization Dynamics of Enterococcus faecalis in Implanted Devices in Research Macaques.

Lieberman MT, Van Tyne D, Dzink-Fox J, Ma EJ, Gilmore MS, Fox JG.

Appl Environ Microbiol. 2018 Aug 31;84(18). pii: e01336-18. doi: 10.1128/AEM.01336-18. Print 2018 Sep 15.


Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus.

Johnston T, Van Tyne D, Chen RF, Fawzi NL, Kwon B, Kelso MJ, Gilmore MS, Mylonakis E.

Sci Rep. 2018 May 4;8(1):7062. doi: 10.1038/s41598-018-25571-w.


A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.

Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.


Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM.

J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24.


Identification of a Functionally Unique Family of Penicillin-Binding Proteins.

Welsh MA, Taguchi A, Schaefer K, Van Tyne D, Lebreton F, Gilmore MS, Kahne D, Walker S.

J Am Chem Soc. 2017 Dec 13;139(49):17727-17730. doi: 10.1021/jacs.7b10170. Epub 2017 Nov 30.


Resistance in In Vitro Selected Tigecycline-Resistant Methicillin-Resistant Staphylococcus aureus Sequence Type 5 Is Driven by Mutations in mepR and mepA Genes.

Dabul ANG, Avaca-Crusca JS, Van Tyne D, Gilmore MS, Camargo ILBC.

Microb Drug Resist. 2018 Jun;24(5):519-526. doi: 10.1089/mdr.2017.0279. Epub 2017 Oct 17.


Raising the Alarmone: Within-Host Evolution of Antibiotic-Tolerant Enterococcus faecium.

Van Tyne D, Gilmore MS.

mBio. 2017 Feb 21;8(1). pii: e00066-17. doi: 10.1128/mBio.00066-17.


High-Quality Draft Genome Sequence of the Multidrug-Resistant Clinical Isolate Enterococcus faecium VRE16.

de Mello SS, Van Tyne D, Dabul AN, Gilmore MS, Camargo IL.

Genome Announc. 2016 Sep 22;4(5). pii: e00992-16. doi: 10.1128/genomeA.00992-16.


Novel Phagocytosis-Resistant Extended-Spectrum β-Lactamase-Producing Escherichia coli From Keratitis.

Van Tyne D, Ciolino JB, Wang J, Durand ML, Gilmore MS.

JAMA Ophthalmol. 2016 Nov 1;134(11):1306-1309. doi: 10.1001/jamaophthalmol.2016.3283.


Virulence Plasmids of Nonsporulating Gram-Positive Pathogens.

Van Tyne D, Gilmore MS.

Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.PLAS-0002-2013. Review.


Plasmodium falciparum gene expression measured directly from tissue during human infection.

Van Tyne D, Tan Y, Daily JP, Kamiza S, Seydel K, Taylor T, Mesirov JP, Wirth DF, Milner DA Jr.

Genome Med. 2014 Nov 29;6(11):110. doi: 10.1186/s13073-014-0110-6. eCollection 2014.


A delicate balance: maintaining mutualism to prevent disease.

Van Tyne D, Gilmore MS.

Cell Host Microbe. 2014 Oct 8;16(4):425-7. doi: 10.1016/j.chom.2014.09.019.


Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers.

Kumar AA, Lim C, Moreno Y, Mace CR, Syed A, Van Tyne D, Wirth DF, Duraisingh MT, Whitesides GM.

Am J Hematol. 2015 Jan;90(1):31-6. doi: 10.1002/ajh.23860. Epub 2014 Oct 18.


Friend turned foe: evolution of enterococcal virulence and antibiotic resistance.

Van Tyne D, Gilmore MS.

Annu Rev Microbiol. 2014;68:337-56. doi: 10.1146/annurev-micro-091213-113003. Epub 2014 Jun 18. Review.


Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal.

Ndiaye D, Dieye B, Ndiaye YD, Van Tyne D, Daniels R, Bei AK, Mbaye A, Valim C, Lukens A, Mboup S, Ndir O, Wirth DF, Volkman S.

Int J Parasitol Drugs Drug Resist. 2013 Aug 12;3:135-42. doi: 10.1016/j.ijpddr.2013.07.001. eCollection 2013 Dec.


Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal.

Van Tyne D, Dieye B, Valim C, Daniels RF, Sène PD, Lukens AK, Ndiaye M, Bei AK, Ndiaye YD, Hamilton EJ, Ndir O, Mboup S, Volkman SK, Wirth DF, Ndiaye D.

Malar J. 2013 Dec 6;12:441. doi: 10.1186/1475-2875-12-441.


Dual defensin strategy for targeting Enterococcus faecalis.

Gilmore MS, Lebreton F, Van Tyne D.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):19980-1. doi: 10.1073/pnas.1319939110. Epub 2013 Nov 27. No abstract available.


Structure, function, and biology of the Enterococcus faecalis cytolysin.

Van Tyne D, Martin MJ, Gilmore MS.

Toxins (Basel). 2013 Apr 29;5(5):895-911. doi: 10.3390/toxins5050895. Review.


Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal.

Daniels R, Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D, Mboup S, Sabeti PC, Ndiaye D, Wirth DF, Hartl DL, Volkman SK.

PLoS One. 2013 Apr 4;8(4):e60780. doi: 10.1371/journal.pone.0060780. Print 2013.


Modulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugs.

Van Tyne D, Uboldi AD, Healer J, Cowman AF, Wirth DF.

Antimicrob Agents Chemother. 2013 Jul;57(7):2937-41. doi: 10.1128/AAC.02574-12. Epub 2013 Apr 15.


Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite.

Park DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C, Ribacke U, Van Tyne D, Galinsky K, Galligan M, Becker JS, Ndiaye D, Mboup S, Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, Volkman SK.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13052-7. doi: 10.1073/pnas.1210585109. Epub 2012 Jul 23.


SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites.

Amambua-Ngwa A, Park DJ, Volkman SK, Barnes KG, Bei AK, Lukens AK, Sene P, Van Tyne D, Ndiaye D, Wirth DF, Conway DJ, Neafsey DE, Schaffner SF.

Mol Biol Evol. 2012 Nov;29(11):3249-53. doi: 10.1093/molbev/mss151. Epub 2012 Jun 11.


Live imaging of mitosomes and hydrogenosomes by HaloTag technology.

Martincová E, Voleman L, Najdrová V, De Napoli M, Eshar S, Gualdron M, Hopp CS, Sanin DE, Tembo DL, Van Tyne D, Walker D, Marcinčiková M, Tachezy J, Doležal P.

PLoS One. 2012;7(4):e36314. doi: 10.1371/journal.pone.0036314. Epub 2012 Apr 27.


Human cerebral malaria and Plasmodium falciparum genotypes in Malawi.

Milner DA Jr, Vareta J, Valim C, Montgomery J, Daniels RF, Volkman SK, Neafsey DE, Park DJ, Schaffner SF, Mahesh NC, Barnes KG, Rosen DM, Lukens AK, Van Tyne D, Wiegand RC, Sabeti PC, Seydel KB, Glover SJ, Kamiza S, Molyneux ME, Taylor TE, Wirth DF.

Malar J. 2012 Feb 7;11:35. doi: 10.1186/1475-2875-11-35.


Hybrid selection for sequencing pathogen genomes from clinical samples.

Melnikov A, Galinsky K, Rogov P, Fennell T, Van Tyne D, Russ C, Daniels R, Barnes KG, Bochicchio J, Ndiaye D, Sene PD, Wirth DF, Nusbaum C, Volkman SK, Birren BW, Gnirke A, Neafsey DE.

Genome Biol. 2011 Aug 11;12(8):R73. doi: 10.1186/gb-2011-12-8-r73.


A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs.

Broadbent KM, Park D, Wolf AR, Van Tyne D, Sims JS, Ribacke U, Volkman S, Duraisingh M, Wirth D, Sabeti PC, Rinn JL.

Genome Biol. 2011 Jun 20;12(6):R56. doi: 10.1186/gb-2011-12-6-r56.


Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC.

PLoS Genet. 2011 Apr;7(4):e1001383. doi: 10.1371/journal.pgen.1001383. Epub 2011 Apr 21.


Discrimination between closely related cellular metabolites by the SAM-I riboswitch.

Montange RK, Mondragón E, van Tyne D, Garst AD, Ceres P, Batey RT.

J Mol Biol. 2010 Feb 26;396(3):761-72. doi: 10.1016/j.jmb.2009.12.007. Epub 2009 Dec 16.


Cohesin regulates VSG monoallelic expression in trypanosomes.

Landeira D, Bart JM, Van Tyne D, Navarro M.

J Cell Biol. 2009 Jul 27;186(2):243-54. doi: 10.1083/jcb.200902119.


Structure of the SAM-II riboswitch bound to S-adenosylmethionine.

Gilbert SD, Rambo RP, Van Tyne D, Batey RT.

Nat Struct Mol Biol. 2008 Feb;15(2):177-82. doi: 10.1038/nsmb.1371. Epub 2008 Jan 20.


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