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Items: 1 to 50 of 328

1.

Argonaute-2 is associated to brown adipose tissue activation.

Roger E, Dumortier O, Pisani DF, Gautier N, Van Obberghen E, Hinault C.

Biochim Biophys Acta Mol Basis Dis. 2019 May 30. pii: S0925-4439(19)30189-9. doi: 10.1016/j.bbadis.2019.05.018. [Epub ahead of print]

PMID:
31152866
2.

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

Cancers (Basel). 2019 Feb 21;11(2). pii: E250. doi: 10.3390/cancers11020250.

3.

Spontaneous adverse event notifications by patients subsequent to the marketing of a new formulation of Levothyrox® amidst a drug media crisis: atypical profile as compared with other drugs.

Viard D, Parassol-Girard N, Romani S, Van Obberghen E, Rocher F, Berriri S, Drici MD.

Fundam Clin Pharmacol. 2018 Dec 21. doi: 10.1111/fcp.12446. [Epub ahead of print]

PMID:
30575110
4.

Contribution of the Long Noncoding RNA H19 to β-Cell Mass Expansion in Neonatal and Adult Rodents.

Sanchez-Parra C, Jacovetti C, Dumortier O, Lee K, Peyot ML, Guay C, Prentki M, Laybutt DR, Van Obberghen E, Regazzi R.

Diabetes. 2018 Nov;67(11):2254-2267. doi: 10.2337/db18-0201. Epub 2018 Aug 16.

5.

Evaluation of the Sensitivity of Inhomogeneous Magnetization Transfer (ihMT) MRI for Multiple Sclerosis.

Van Obberghen E, Mchinda S, le Troter A, Prevost VH, Viout P, Guye M, Varma G, Alsop DC, Ranjeva JP, Pelletier J, Girard O, Duhamel G.

AJNR Am J Neuroradiol. 2018 Apr;39(4):634-641. doi: 10.3174/ajnr.A5563. Epub 2018 Feb 22.

6.

Multiple immune disorders after natalizumab discontinuation: After the CIRIS, the SIRIS?

Van Obberghen EK, Cohen M, Rocher F, Lebrun-Frenay C.

Rev Neurol (Paris). 2017 Apr;173(4):222-224. doi: 10.1016/j.neurol.2017.03.008. Epub 2017 Mar 31.

PMID:
28372806
7.

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance.

Wagner R, Hakaste LH, Ahlqvist E, Heni M, Machann J, Schick F, Van Obberghen E, Stefan N, Gallwitz B, Tuomi T, Häring HU, Groop L, Fritsche A.

Diabetes. 2017 May;66(5):1373-1379. doi: 10.2337/db16-0354. Epub 2016 Dec 16.

8.

Age-Dependent Control of Energy Homeostasis by Brown Adipose Tissue in Progeny Subjected to Maternal Diet-Induced Fetal Programming.

Dumortier O, Roger E, Pisani DF, Casamento V, Gautier N, Lebrun P, Johnston H, Lopez P, Amri EZ, Jousse C, Fafournoux P, Prentki M, Hinault C, Van Obberghen E.

Diabetes. 2017 Mar;66(3):627-639. doi: 10.2337/db16-0956. Epub 2016 Dec 7.

9.

Shaping and preserving β-cell identity with microRNAs.

Dumortier O, Fabris G, Van Obberghen E.

Diabetes Obes Metab. 2016 Sep;18 Suppl 1:51-7. doi: 10.1111/dom.12722. Review.

PMID:
27615131
10.

Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes.

Pisani DF, Dumortier O, Beranger GE, Casamento V, Ghandour RA, Giroud M, Gautier N, Balaguer T, Chambard JC, Virtanen KA, Nuutila P, Niemi T, Taittonen M, Van Obberghen E, Hinault C, Amri EZ.

Adipocyte. 2015 Dec 9;5(2):186-95. doi: 10.1080/21623945.2015.1122854. eCollection 2016 Apr-Jun.

11.

RNA Activation of the Vascular Endothelial Growth Factor Gene (VEGF) Promoter by Double-Stranded RNA and Hypoxia: Role of Noncoding VEGF Promoter Transcripts.

Lopez P, Wagner KD, Hofman P, Van Obberghen E.

Mol Cell Biol. 2016 May 2;36(10):1480-93. doi: 10.1128/MCB.01096-15. Print 2016 May 15.

12.

Circulating microRNAs and diabetes: potential applications in medical practice.

Raffort J, Hinault C, Dumortier O, Van Obberghen E.

Diabetologia. 2015 Sep;58(9):1978-92. doi: 10.1007/s00125-015-3680-y. Epub 2015 Jul 9. Review.

PMID:
26155747
13.

Modulation of glucose metabolism by the renin-angiotensin-aldosterone system.

Favre GA, Esnault VL, Van Obberghen E.

Am J Physiol Endocrinol Metab. 2015 Mar 15;308(6):E435-49. doi: 10.1152/ajpendo.00391.2014. Epub 2015 Jan 6. Review.

14.

Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice.

Favre GA, Lebrun P, Lopez P, Butori C, Hofman P, Esnault VL, Van Obberghen E.

J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):396-409. doi: 10.1177/1470320314537695. Epub 2014 Nov 4.

PMID:
25371094
15.

Incidence and characteristics of acute kidney injury in severe diabetic ketoacidosis.

Orban JC, Maizière EM, Ghaddab A, Van Obberghen E, Ichai C.

PLoS One. 2014 Oct 22;9(10):e110925. doi: 10.1371/journal.pone.0110925. eCollection 2014.

16.

Maternal protein restriction leads to pancreatic failure in offspring: role of misexpressed microRNA-375.

Dumortier O, Hinault C, Gautier N, Patouraux S, Casamento V, Van Obberghen E.

Diabetes. 2014 Oct;63(10):3416-27. doi: 10.2337/db13-1431. Epub 2014 May 16.

17.

Fast urinary screening of oligosaccharidoses by MALDI-TOF/TOF mass spectrometry.

Bonesso L, Piraud M, Caruba C, Van Obberghen E, Mengual R, Hinault C.

Orphanet J Rare Dis. 2014 Feb 6;9:19. doi: 10.1186/1750-1172-9-19.

18.

[microRNA and diabetes: tiny things causing huge effects].

Hinault C, Dumortier O, Van Obberghen E.

Med Sci (Paris). 2013 Aug-Sep;29(8-9):785-90. doi: 10.1051/medsci/2013298019. Epub 2013 Sep 5. Review. French.

19.

MicroRNAs and metabolism crosstalk in energy homeostasis.

Dumortier O, Hinault C, Van Obberghen E.

Cell Metab. 2013 Sep 3;18(3):312-24. doi: 10.1016/j.cmet.2013.06.004. Epub 2013 Jul 11. Review.

20.

MicroRNAs in pancreas development.

Dumortier O, Van Obberghen E.

Diabetes Obes Metab. 2012 Oct;14 Suppl 3:22-8. doi: 10.1111/j.1463-1326.2012.01656.x. Review.

PMID:
22928561
21.

Adipocytes secrete leukotrienes: contribution to obesity-associated inflammation and insulin resistance in mice.

Mothe-Satney I, Filloux C, Amghar H, Pons C, Bourlier V, Galitzky J, Grimaldi PA, Féral CC, Bouloumié A, Van Obberghen E, Neels JG.

Diabetes. 2012 Sep;61(9):2311-9. doi: 10.2337/db11-1455. Epub 2012 Jun 11.

22.

Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E.

Fiory F, Lombardi A, Miele C, Giudicelli J, Beguinot F, Van Obberghen E.

Diabetologia. 2011 Nov;54(11):2941-52. doi: 10.1007/s00125-011-2280-8. Epub 2011 Aug 23. Erratum in: Diabetologia. 2012 Jan;55(1):272.

PMID:
21861178
23.

Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells.

Arous C, Naïmi M, Van Obberghen E.

Diabetologia. 2011 Apr;54(4):954-64. doi: 10.1007/s00125-010-2032-1. Epub 2011 Jan 15.

PMID:
21240477
24.

The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion.

Lebrun P, Cognard E, Gontard P, Bellon-Paul R, Filloux C, Berthault MF, Magnan C, Ruberte J, Luppo M, Pujol A, Pachera N, Herchuelz A, Bosch F, Van Obberghen E.

Diabetologia. 2010 Sep;53(9):1935-46. doi: 10.1007/s00125-010-1786-9. Epub 2010 May 25.

PMID:
20499047
25.

Function of microRNA-375 and microRNA-124a in pancreas and brain.

Baroukh NN, Van Obberghen E.

FEBS J. 2009 Nov;276(22):6509-21. doi: 10.1111/j.1742-4658.2009.07353.x. Review.

26.

Inflammation: where is the SPARC in adipose-tissue inflammation?

Naïmi M, Van Obberghen E.

Nat Rev Endocrinol. 2009 Dec;5(12):648-9. doi: 10.1038/nrendo.2009.220. No abstract available.

PMID:
19924149
27.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV.

Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E179-92. doi: 10.1152/ajpendo.00392.2009. Epub 2009 Nov 3.

28.

miR-139 impacts FoxO1 action by decreasing FoxO1 protein in mouse hepatocytes.

Hasseine LK, Hinault C, Lebrun P, Gautier N, Paul-Bellon R, Van Obberghen E.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1278-82. doi: 10.1016/j.bbrc.2009.10.135. Epub 2009 Oct 31.

PMID:
19883627
29.

Energetic cell sensors: a key to metabolic homeostasis.

Naïmi M, Arous C, Van Obberghen E.

Trends Endocrinol Metab. 2010 Feb;21(2):75-82. doi: 10.1016/j.tem.2009.09.003. Epub 2009 Oct 12. Review.

PMID:
19819719
30.

Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice.

Lebrun P, Cognard E, Bellon-Paul R, Gontard P, Filloux C, Jehl-Pietri C, Grimaldi P, Samson M, Pénicaud L, Ruberte J, Ferre T, Pujol A, Bosch F, Van Obberghen E.

Diabetologia. 2009 Oct;52(10):2201-12. doi: 10.1007/s00125-009-1474-9. Epub 2009 Aug 12.

PMID:
19672574
31.

In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs.

Cassese A, Esposito I, Fiory F, Barbagallo AP, Paturzo F, Mirra P, Ulianich L, Giacco F, Iadicicco C, Lombardi A, Oriente F, Van Obberghen E, Beguinot F, Formisano P, Miele C.

J Biol Chem. 2008 Dec 26;283(52):36088-99. doi: 10.1074/jbc.M801698200. Epub 2008 Oct 27.

32.

Effects of age, malnutrition and refeeding on the expression and secretion of ghrelin.

Schneider SM, Al-Jaouni R, Caruba C, Giudicelli J, Arab K, Suavet F, Ferrari P, Mothe-Satney I, Van Obberghen E, Hébuterne X.

Clin Nutr. 2008 Oct;27(5):724-31. doi: 10.1016/j.clnu.2008.07.006. Epub 2008 Sep 10.

PMID:
18783854
33.

Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.

Cursio R, Miele C, Filippa N, Colosetti P, Auberger P, Van Obberghen E, Gugenheim J.

Langenbecks Arch Surg. 2009 Jan;394(1):123-31. doi: 10.1007/s00423-008-0394-3. Epub 2008 Aug 5.

PMID:
18679708
34.

Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats.

Cursio R, Miele C, Filippa N, Van Obberghen E, Gugenheim J.

Transplant Proc. 2008 Jul-Aug;40(6):2042-5. doi: 10.1016/j.transproceed.2008.05.037.

PMID:
18675125
35.

[Nuclear FoxO1 as a bridge between metabolism and mitogenesis].

Naïmi M, Van Obberghen E.

Med Sci (Paris). 2008 Jun-Jul;24(6-7):635-9. doi: 10.1051/medsci/20082467635. French.

36.

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells.

El Ouaamari A, Baroukh N, Martens GA, Lebrun P, Pipeleers D, van Obberghen E.

Diabetes. 2008 Oct;57(10):2708-17. doi: 10.2337/db07-1614. Epub 2008 Jun 30.

37.

Nutritional and genetic determinants of vitamin B and homocysteine metabolisms in neural tube defects: a multicenter case-control study.

Candito M, Rivet R, Herbeth B, Boisson C, Rudigoz RC, Luton D, Journel H, Oury JF, Roux F, Saura R, Vernhet I, Gaucherand P, Muller F, Guidicelli B, Heckenroth H, Poulain P, Blayau M, Francannet C, Roszyk L, Brustié C, Staccini P, Gérard P, Fillion-Emery N, Guéant-Rodriguez RM, Van Obberghen E, Guéant JL.

Am J Med Genet A. 2008 May 1;146A(9):1128-33. doi: 10.1002/ajmg.a.32199.

PMID:
18386810
38.

5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.

Endocrinology. 2008 Apr;149(4):1490-8. doi: 10.1210/en.2007-1326. Epub 2008 Jan 10.

PMID:
18187546
39.

FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes.

Demozay D, Mas JC, Rocchi S, Van Obberghen E.

Diabetes. 2008 May;57(5):1216-26. doi: 10.2337/db07-0389. Epub 2008 Jan 3.

40.

SOCS proteins causing trouble in insulin action.

Lebrun P, Van Obberghen E.

Acta Physiol (Oxf). 2008 Jan;192(1):29-36. doi: 10.1111/j.1748-1716.2007.01782.x. Review.

PMID:
18171427
41.

MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines.

Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E.

J Biol Chem. 2007 Jul 6;282(27):19575-88. Epub 2007 Apr 26.

42.

Hrs is a positive regulator of VEGF and insulin signaling.

Hasseine LK, Murdaca J, Suavet F, Longnus S, Giorgetti-Peraldi S, Van Obberghen E.

Exp Cell Res. 2007 May 15;313(9):1927-42. Epub 2007 Mar 21.

PMID:
17445799
43.

Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.

Naïmi M, Gautier N, Chaussade C, Valverde AM, Accili D, Van Obberghen E.

Endocrinology. 2007 May;148(5):2424-34. Epub 2007 Feb 15. Erratum in: Endocrinology. 2007 Jul;148(7):3517.

44.

Spontaneous hypoglycaemia in the presence of both anti-insulin antibody and anti-insulin receptor antibody.

Bortolotti D, Mothe-Satney I, Ferrari P, Gautier N, Sonke J, Pallé S, Bernard G, Badetti JL, Fredenrich A, Van Obberghen E, Canivet B.

Diabetes Metab. 2006 Dec;32(6):598-603.

PMID:
17296513
45.

Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion.

Cursio R, Miele C, Filippa N, Van Obberghen E, Gugenheim J.

Transplant Proc. 2006 Dec;38(10):3362-5.

PMID:
17175272
46.

Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.

Chavey C, Boucher J, Monthouël-Kartmann MN, Sage EH, Castan-Laurell I, Valet P, Tartare-Deckert S, Van Obberghen E.

Obesity (Silver Spring). 2006 Nov;14(11):1890-7.

47.

Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.

Candito M, Naimi M, Boisson C, Rudigoz JC, Gaucherand P, Guéant JL, Luton D, Van Obberghen E.

Birth Defects Res A Clin Mol Teratol. 2007 Jan;79(1):62-4.

PMID:
17120234
48.

[Homocysteinemia and thrombophilic factors in unexplained decompression sickness].

Candito M, Candito E, Chatel M, van Obberghen E, Dunac A.

Rev Neurol (Paris). 2006 Sep;162(8-9):840-4. French.

PMID:
17028545
49.

Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver ischaemia-reperfusion injury.

Cursio R, Filippa N, Miele C, Van Obberghen E, Gugenheim J.

Br J Surg. 2006 Jun;93(6):752-61.

PMID:
16671069
50.

Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species.

Riboulet-Chavey A, Pierron A, Durand I, Murdaca J, Giudicelli J, Van Obberghen E.

Diabetes. 2006 May;55(5):1289-99.

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