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Items: 1 to 50 of 57

1.

Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: A multicentre, prospective study.

Van Loon E, Gazut S, Yazdani S, Lerut E, de Loor H, Coemans M, Noël LH, Thorrez L, Van Lommel L, Schuit F, Sprangers B, Kuypers D, Essig M, Gwinner W, Anglicheau D, Marquet P, Naesens M.

EBioMedicine. 2019 Aug;46:463-472. doi: 10.1016/j.ebiom.2019.07.028. Epub 2019 Aug 1.

2.

GC content of vertebrate exome landscapes reveal areas of accelerated protein evolution.

Huttener R, Thorrez L, In't Veld T, Granvik M, Snoeck L, Van Lommel L, Schuit F.

BMC Evol Biol. 2019 Jul 16;19(1):144. doi: 10.1186/s12862-019-1469-1.

3.

COX6A2 variants cause a muscle-specific cytochrome c oxidase deficiency.

Inoue M, Uchino S, Iida A, Noguchi S, Hayashi S, Takahashi T, Fujii K, Komaki H, Takeshita E, Nonaka I, Okada Y, Yoshizawa T, Van Lommel L, Schuit F, Goto YI, Mimaki M, Nishino I.

Ann Neurol. 2019 Aug;86(2):193-202. doi: 10.1002/ana.25517. Epub 2019 Jul 2.

PMID:
31155743
4.

Gene and Mirna Regulatory Networks During Different Stages of Crohn's Disease.

Verstockt S, De Hertogh G, Van der Goten J, Verstockt B, Vancamelbeke M, Machiels K, Van Lommel L, Schuit F, Van Assche G, Rutgeerts P, Ferrante M, Vermeire S, Arijs I, Cleynen I.

J Crohns Colitis. 2019 Jul 25;13(7):916-930. doi: 10.1093/ecco-jcc/jjz007.

PMID:
30657881
5.

Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation.

Yazdani S, Callemeyn J, Gazut S, Lerut E, de Loor H, Wevers M, Heylen L, Saison C, Koenig A, Thaunat O, Thorrez L, Kuypers D, Sprangers B, Noël LH, Van Lommel L, Schuit F, Essig M, Gwinner W, Anglicheau D, Marquet P, Naesens M.

Kidney Int. 2019 Jan;95(1):188-198. doi: 10.1016/j.kint.2018.08.027. Epub 2018 Nov 3.

6.

How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

Lemaire K, Granvik M, Schraenen A, Goyvaerts L, Van Lommel L, Gómez-Ruiz A, In 't Veld P, Gilon P, Schuit F.

PLoS One. 2017 Aug 9;12(8):e0181651. doi: 10.1371/journal.pone.0181651. eCollection 2017.

7.

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.

Crèvecoeur I, Gudmundsdottir V, Vig S, Marques Câmara Sodré F, D'Hertog W, Fierro AC, Van Lommel L, Gysemans C, Marchal K, Waelkens E, Schuit F, Brunak S, Overbergh L, Mathieu C.

Diabetologia. 2017 Mar;60(3):475-489. doi: 10.1007/s00125-016-4191-1. Epub 2017 Jan 12.

PMID:
28078386
8.

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC.

Arijs I, De Hertogh G, Lemmens B, Van Lommel L, de Bruyn M, Vanhove W, Cleynen I, Machiels K, Ferrante M, Schuit F, Van Assche G, Rutgeerts P, Vermeire S.

Gut. 2018 Jan;67(1):43-52. doi: 10.1136/gutjnl-2016-312293. Epub 2016 Oct 7.

PMID:
27802155
9.

Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis.

Breynaert C, de Bruyn M, Arijs I, Cremer J, Martens E, Van Lommel L, Geboes K, De Hertogh G, Schuit F, Ferrante M, Vermeire S, Ceuppens J, Opdenakker G, Van Assche G.

J Crohns Colitis. 2016 Nov;10(11):1336-1350. Epub 2016 May 17.

PMID:
27194531
10.

Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice.

Vangoitsenhoven R, Wolden-Kirk H, Lemaire K, Verstuyf A, Verlinden L, Yamamoto Y, Kato S, Van Lommel L, Schuit F, Van der Schueren B, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2016 Nov;164:309-317. doi: 10.1016/j.jsbmb.2016.02.011. Epub 2016 Feb 11.

PMID:
26877201
11.

Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.

Stijnen P, Brouwers B, Dirkx E, Ramos-Molina B, Van Lommel L, Schuit F, Thorrez L, Declercq J, Creemers JW.

Int J Obes (Lond). 2016 Jun;40(6):973-81. doi: 10.1038/ijo.2016.3. Epub 2016 Jan 20.

PMID:
26786350
12.

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Vanhove W, Peeters PM, Staelens D, Schraenen A, Van der Goten J, Cleynen I, De Schepper S, Van Lommel L, Reynaert NL, Schuit F, Van Assche G, Ferrante M, De Hertogh G, Wouters EF, Rutgeerts P, Vermeire S, Nys K, Arijs I.

Inflamm Bowel Dis. 2015 Nov;21(11):2673-82. doi: 10.1097/MIB.0000000000000535.

PMID:
26313692
13.

Prolactin receptors and placental lactogen drive male mouse pancreatic islets to pregnancy-related mRNA changes.

Goyvaerts L, Lemaire K, Arijs I, Auffret J, Granvik M, Van Lommel L, Binart N, in't Veld P, Schuit F, Schraenen A.

PLoS One. 2015 Mar 27;10(3):e0121868. doi: 10.1371/journal.pone.0121868. eCollection 2015.

14.

Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways.

Ferreira GB, Vanherwegen AS, Eelen G, Gutiérrez ACF, Van Lommel L, Marchal K, Verlinden L, Verstuyf A, Nogueira T, Georgiadou M, Schuit F, Eizirik DL, Gysemans C, Carmeliet P, Overbergh L, Mathieu C.

Cell Rep. 2015 Feb 10;10(5):711-725. doi: 10.1016/j.celrep.2015.01.013. Epub 2015 Feb 7.

15.

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Van der Goten J, Vanhove W, Lemaire K, Van Lommel L, Machiels K, Wollants WJ, De Preter V, De Hertogh G, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I.

PLoS One. 2014 Dec 29;9(12):e116117. doi: 10.1371/journal.pone.0116117. eCollection 2014.

16.

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A.

Cell Metab. 2014 Dec 2;20(6):979-90. doi: 10.1016/j.cmet.2014.11.004.

17.

A complex Xp11.22 deletion in a patient with syndromic autism: exploration of FAM120C as a positional candidate gene for autism.

De Wolf V, Crepel A, Schuit F, van Lommel L, Ceulemans B, Steyaert J, Seuntjens E, Peeters H, Devriendt K.

Am J Med Genet A. 2014 Dec;164A(12):3035-41. doi: 10.1002/ajmg.a.36752. Epub 2014 Sep 24.

PMID:
25258334
18.

Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.

Wolden-Kirk H, Rondas D, Bugliani M, Korf H, Van Lommel L, Brusgaard K, Christesen HT, Schuit F, Proost P, Masini M, Marchetti P, Eizirik DL, Overbergh L, Mathieu C.

Endocrinology. 2014 Mar;155(3):736-47. doi: 10.1210/en.2013-1409. Epub 2014 Jan 1.

PMID:
24424042
19.

Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease.

de Bruyn M, Machiels K, Vandooren J, Lemmens B, Van Lommel L, Breynaert C, Van der Goten J, Staelens D, Billiet T, De Hertogh G, Ferrante M, Van Assche G, Vermeire S, Opdenakker G, Schuit F, Rutgeerts P, Arijs I.

Inflamm Bowel Dis. 2014 Feb;20(2):339-52. doi: 10.1097/01.MIB.0000438430.15553.90.

PMID:
24378596
20.

Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration.

Mannaerts I, Schroyen B, Verhulst S, Van Lommel L, Schuit F, Nyssen M, van Grunsven LA.

PLoS One. 2013 Dec 17;8(12):e84071. doi: 10.1371/journal.pone.0084071. eCollection 2013.

21.

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

Breynaert C, Dresselaers T, Perrier C, Arijs I, Cremer J, Van Lommel L, Van Steen K, Ferrante M, Schuit F, Vermeire S, Rutgeerts P, Himmelreich U, Ceuppens JL, Geboes K, Van Assche G.

PLoS One. 2013 Jul 23;8(7):e68876. doi: 10.1371/journal.pone.0068876. Print 2013.

22.

Characterization of proposed human B-1 cells reveals pre-plasmablast phenotype.

Covens K, Verbinnen B, Geukens N, Meyts I, Schuit F, Van Lommel L, Jacquemin M, Bossuyt X.

Blood. 2013 Jun 27;121(26):5176-83. doi: 10.1182/blood-2012-12-471953. Epub 2013 Apr 23.

PMID:
23613519
23.

Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.

Quintens R, Singh S, Lemaire K, De Bock K, Granvik M, Schraenen A, Vroegrijk IO, Costa V, Van Noten P, Lambrechts D, Lehnert S, Van Lommel L, Thorrez L, De Faudeur G, Romijn JA, Shelton JM, Scorrano L, Lijnen HR, Voshol PJ, Carmeliet P, Mammen PP, Schuit F.

PLoS One. 2013;8(2):e56719. doi: 10.1371/journal.pone.0056719. Epub 2013 Feb 27.

24.

Unraveling the effects of 1,25OH2D3 on global gene expression in pancreatic islets.

Wolden-Kirk H, Overbergh L, Gysemans C, Brusgaard K, Naamane N, Van Lommel L, Schuit F, Eizirik DL, Christesen H, Mathieu C.

J Steroid Biochem Mol Biol. 2013 Jul;136:68-79. doi: 10.1016/j.jsbmb.2012.10.017. Epub 2012 Nov 5.

PMID:
23137852
25.

Endometrial gene expression in the early luteal phase is impacted by mode of triggering final oocyte maturation in recFSH stimulated and GnRH antagonist co-treated IVF cycles.

Humaidan P, Van Vaerenbergh I, Bourgain C, Alsbjerg B, Blockeel C, Schuit F, Van Lommel L, Devroey P, Fatemi H.

Hum Reprod. 2012 Nov;27(11):3259-72. doi: 10.1093/humrep/des279. Epub 2012 Aug 28.

PMID:
22930004
26.

β-cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion?

Schuit F, Van Lommel L, Granvik M, Goyvaerts L, de Faudeur G, Schraenen A, Lemaire K.

Diabetes. 2012 May;61(5):969-75. doi: 10.2337/db11-1564. No abstract available.

27.

Clusters of conserved beta cell marker genes for assessment of beta cell phenotype.

Martens GA, Jiang L, Hellemans KH, Stangé G, Heimberg H, Nielsen FC, Sand O, Van Helden J, Van Lommel L, Schuit F, Gorus FK, Pipeleers DG.

PLoS One. 2011;6(9):e24134. doi: 10.1371/journal.pone.0024134. Epub 2011 Sep 2. Erratum in: PLoS One. 2012;7(1). doi: 10.1371/annotation/a91571a6-acbb-456f-bcc5-f4a431e28516. PLoS One. 2012;7(1). doi:10.1371/annotation/13c6d084-a8fd-4019-a3cf-12a0d8abe309.. Van Lommel, Leentje [added], Schuit, Frans [added]. PLoS One. 2012;7(1). doi:10.1371/annotation/4aae21a9-e176-4feb-9f15-103b265d3335. PLoS One. 2012;7(1). doi:10.1371/annotation/7aa0ff33-5660-4b56-889a-4b86a273d522.

28.

Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment.

Arijs I, De Hertogh G, Machiels K, Van Steen K, Lemaire K, Schraenen A, Van Lommel L, Quintens R, Van Assche G, Vermeire S, Schuit F, Rutgeerts P.

Am J Gastroenterol. 2011 Apr;106(4):748-61. doi: 10.1038/ajg.2011.27. Epub 2011 Feb 15.

PMID:
21326222
29.

Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism.

Declercq J, Kumar A, Gysemans C, Di Pietro C, Schraenen A, Chintinne M, Lemaire K, Van Lommel L, Van De Casteele M, Heimberg H, Pipeleers D, Schuit FC, Mathieu C, Ectors N, Van de Ven WJ, Verfaillie CM.

Cell Transplant. 2011;20(8):1285-97. doi: 10.3727/096368910X550242. Epub 2011 Feb 3.

PMID:
21294959
30.

Progesterone rise on HCG day in GnRH antagonist/rFSH stimulated cycles affects endometrial gene expression.

Van Vaerenbergh I, Fatemi HM, Blockeel C, Van Lommel L, In't Veld P, Schuit F, Kolibianakis EM, Devroey P, Bourgain C.

Reprod Biomed Online. 2011 Mar;22(3):263-71. doi: 10.1016/j.rbmo.2010.11.002. Epub 2010 Nov 13.

PMID:
21273126
31.

The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.

Baeke F, Korf H, Overbergh L, Verstuyf A, Thorrez L, Van Lommel L, Waer M, Schuit F, Gysemans C, Mathieu C.

J Immunol. 2011 Jan 1;186(1):132-42. doi: 10.4049/jimmunol.1000695. Epub 2010 Dec 3.

32.

Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation.

Thorrez L, Laudadio I, Van Deun K, Quintens R, Hendrickx N, Granvik M, Lemaire K, Schraenen A, Van Lommel L, Lehnert S, Aguayo-Mazzucato C, Cheng-Xue R, Gilon P, Van Mechelen I, Bonner-Weir S, Lemaigre F, Schuit F.

Genome Res. 2011 Jan;21(1):95-105. doi: 10.1101/gr.109173.110. Epub 2010 Nov 18.

33.

EuroDia: a beta-cell gene expression resource.

Liechti R, Csárdi G, Bergmann S, Schütz F, Sengstag T, Boj SF, Servitja JM, Ferrer J, Van Lommel L, Schuit F, Klinger S, Thorens B, Naamane N, Eizirik DL, Marselli L, Bugliani M, Marchetti P, Lucas S, Holm C, Jongeneel CV, Xenarios I.

Database (Oxford). 2010 Oct 12;2010:baq024. doi: 10.1093/database/baq024.

34.

Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy.

Schraenen A, Lemaire K, de Faudeur G, Hendrickx N, Granvik M, Van Lommel L, Mallet J, Vodjdani G, Gilon P, Binart N, in't Veld P, Schuit F.

Diabetologia. 2010 Dec;53(12):2589-99. doi: 10.1007/s00125-010-1913-7. Epub 2010 Oct 7.

35.

mRNA expression analysis of cell cycle genes in islets of pregnant mice.

Schraenen A, de Faudeur G, Thorrez L, Lemaire K, Van Wichelen G, Granvik M, Van Lommel L, in't Veld P, Schuit F.

Diabetologia. 2010 Dec;53(12):2579-88. doi: 10.1007/s00125-010-1912-8. Epub 2010 Oct 1.

36.

Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease.

Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Lemaire K, Schraenen A, Perrier C, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P.

Inflamm Bowel Dis. 2010 Dec;16(12):2090-8. doi: 10.1002/ibd.21301.

PMID:
20848504
37.

Cyclooxygenase-2 network as predictive molecular marker for clinical pregnancy in in vitro fertilization.

Van Vaerenbergh I, Blockeel C, Van Lommel L, Ghislain V, In't Veld P, Schuit F, Fatemi HM, Devroey P, Bourgain C.

Fertil Steril. 2011 Jan;95(1):448-51, 451.e1-2. doi: 10.1016/j.fertnstert.2010.07.1061. Epub 2010 Aug 25.

PMID:
20800227
38.

Gene expression profile in the endometrium on the day of oocyte retrieval after ovarian stimulation with low-dose hCG in the follicular phase.

Blockeel C, Van Vaerenbergh I, Fatemi HM, Van Lommel L, Devroey P, Bourgain C.

Mol Hum Reprod. 2011 Jan;17(1):33-41. doi: 10.1093/molehr/gaq070. Epub 2010 Aug 12.

PMID:
20705718
39.

Seroreactivity against glycolytic enzymes in inflammatory bowel disease.

Vermeulen N, Vermeire S, Arijs I, Michiels G, Ballet V, Derua R, Waelkens E, Van Lommel L, Schuit F, Rutgeerts P, Bossuyt X.

Inflamm Bowel Dis. 2011 Feb;17(2):557-64. doi: 10.1002/ibd.21388.

PMID:
20629101
40.

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, Wielinga PY, Schraenen A, Lemaire K, Debray S, Van Lommel L, Pospisilik JA, Tschopp O, Schultze SM, Malipiero U, Esterbauer H, Ellingsgaard H, Rütti S, Schuit FC, Lutz TA, Böni-Schnetzler M, Konrad D, Donath MY.

Diabetologia. 2010 Aug;53(8):1795-806. doi: 10.1007/s00125-010-1747-3. Epub 2010 Apr 21.

PMID:
20407745
41.

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice.

Colsoul B, Schraenen A, Lemaire K, Quintens R, Van Lommel L, Segal A, Owsianik G, Talavera K, Voets T, Margolskee RF, Kokrashvili Z, Gilon P, Nilius B, Schuit FC, Vennekens R.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5208-13. doi: 10.1073/pnas.0913107107. Epub 2010 Mar 1.

42.

Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.

Arijs I, De Hertogh G, Lemaire K, Quintens R, Van Lommel L, Van Steen K, Leemans P, Cleynen I, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P.

PLoS One. 2009 Nov 24;4(11):e7984. doi: 10.1371/journal.pone.0007984.

43.

Gene expression during successful implantation in a natural cycle.

Van Vaerenbergh I, McIntire R, Van Lommel L, Devroey P, Giudice L, Bourgain C.

Fertil Steril. 2010 Jan;93(1):268.e15-8. doi: 10.1016/j.fertnstert.2009.08.057. Epub 2009 Oct 31.

44.

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18.

45.

Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis.

Arijs I, Li K, Toedter G, Quintens R, Van Lommel L, Van Steen K, Leemans P, De Hertogh G, Lemaire K, Ferrante M, Schnitzler F, Thorrez L, Ma K, Song XY, Marano C, Van Assche G, Vermeire S, Geboes K, Schuit F, Baribaud F, Rutgeerts P.

Gut. 2009 Dec;58(12):1612-9. doi: 10.1136/gut.2009.178665. Epub 2009 Aug 20.

PMID:
19700435
46.

Testing the hypothesis of tissue selectivity: the intersection-union test and a Bayesian approach.

Van Deun K, Hoijtink H, Thorrez L, Van Lommel L, Schuit F, Van Mechelen I.

Bioinformatics. 2009 Oct 1;25(19):2588-94. doi: 10.1093/bioinformatics/btp439. Epub 2009 Aug 11.

47.

In GnRH antagonist/rec-FSH stimulated cycles, advanced endometrial maturation on the day of oocyte retrieval correlates with altered gene expression.

Van Vaerenbergh I, Van Lommel L, Ghislain V, In't Veld P, Schuit F, Fatemi HM, Devroey P, Bourgain C.

Hum Reprod. 2009 May;24(5):1085-91. doi: 10.1093/humrep/den501. Epub 2009 Jan 27.

PMID:
19176542
48.

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations.

Bensellam M, Van Lommel L, Overbergh L, Schuit FC, Jonas JC.

Diabetologia. 2009 Mar;52(3):463-76. doi: 10.1007/s00125-008-1245-z. Epub 2009 Jan 23.

PMID:
19165461
49.

Interleukin-6 regulates pancreatic alpha-cell mass expansion.

Ellingsgaard H, Ehses JA, Hammar EB, Van Lommel L, Quintens R, Martens G, Kerr-Conte J, Pattou F, Berney T, Pipeleers D, Halban PA, Schuit FC, Donath MY.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13163-8. doi: 10.1073/pnas.0801059105. Epub 2008 Aug 21.

50.

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P.

Science. 2008 May 23;320(5879):1085-8. doi: 10.1126/science.1156849. Epub 2008 May 1.

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