Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 18

1.

Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells.

Van Hoecke L, Raes L, Stremersch S, Brans T, Fraire JC, Roelandt R, Declercq W, Vandenabeele P, Raemdonck K, Braeckmans K, Saelens X.

Int J Mol Sci. 2019 Aug 30;20(17). pii: E4254. doi: 10.3390/ijms20174254.

2.

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice.

Joe PT, Christopoulou I, van Hoecke L, Schepens B, Ysenbaert T, Heirman C, Thielemans K, Saelens X, Aerts JL.

J Transl Med. 2019 Jul 25;17(1):242. doi: 10.1186/s12967-019-1991-3.

3.

Therapeutic anti-tumor immunity directed against neo-epitopes by intratumor delivery of mRNA encoding MLKL.

Van Hoecke L, Saelens X.

Cell Stress. 2018 Oct 2;2(10):279-281. doi: 10.15698/cst2018.10.160.

4.

Mx1 in Hematopoietic Cells Protects against Thogoto Virus Infection.

Spitaels J, Van Hoecke L, Roose K, Kochs G, Saelens X.

J Virol. 2019 Jul 17;93(15). pii: e00193-19. doi: 10.1128/JVI.00193-19. Print 2019 Aug 1.

PMID:
31092574
5.

How mRNA therapeutics are entering the monoclonal antibody field.

Van Hoecke L, Roose K.

J Transl Med. 2019 Feb 22;17(1):54. doi: 10.1186/s12967-019-1804-8. Review.

6.

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.

Van Hoecke L, Van Lint S, Roose K, Van Parys A, Vandenabeele P, Grooten J, Tavernier J, De Koker S, Saelens X.

Nat Commun. 2018 Aug 24;9(1):3417. doi: 10.1038/s41467-018-05979-8.

7.

Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy.

Merckx P, De Backer L, Van Hoecke L, Guagliardo R, Echaide M, Baatsen P, Olmeda B, Saelens X, Pérez-Gil J, De Smedt SC, Raemdonck K.

Acta Biomater. 2018 Sep 15;78:236-246. doi: 10.1016/j.actbio.2018.08.012. Epub 2018 Aug 15.

PMID:
30118853
8.

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.

Nuhn L, Van Hoecke L, Deswarte K, Schepens B, Li Y, Lambrecht BN, De Koker S, David SA, Saelens X, De Geest BG.

Biomaterials. 2018 Sep;178:643-651. doi: 10.1016/j.biomaterials.2018.03.026. Epub 2018 Mar 16.

PMID:
29573820
9.

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

Van Herck S, Van Hoecke L, Louage B, Lybaert L, De Coen R, Kasmi S, Esser-Kahn AP, David SA, Nuhn L, Schepens B, Saelens X, De Geest BG.

Bioconjug Chem. 2018 Mar 21;29(3):748-760. doi: 10.1021/acs.bioconjchem.7b00641. Epub 2017 Dec 13.

PMID:
29172458
10.

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12.

De Koker S, Van Hoecke L, De Beuckelaer A, Roose K, Deswarte K, Willart MA, Bogaert P, Naessens T, De Geest BG, Saelens X, Lambrecht BN, Grooten J.

Sci Rep. 2017 Jul 20;7(1):5986. doi: 10.1038/s41598-017-06236-6.

11.

Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration.

Van Hoecke L, Job ER, Saelens X, Roose K.

J Vis Exp. 2017 May 4;(123). doi: 10.3791/55398.

12.

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.

Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S.

Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201601412. Epub 2017 Apr 24.

PMID:
28436620
13.

Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1.

Verhelst J, Van Hoecke L, Spitaels J, De Vlieger D, Kolpe A, Saelens X.

J Biol Chem. 2017 Feb 10;292(6):2226-2236. doi: 10.1074/jbc.M116.748806. Epub 2016 Dec 23.

14.

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice.

Smet M, Van Hoecke L, De Beuckelaer A, Vander Beken S, Naessens T, Vergote K, Willart M, Lambrecht BN, Gustafsson JÅ, Steffensen KR, Grooten J.

Immun Inflamm Dis. 2016 Aug 2;4(3):350-61. doi: 10.1002/iid3.118. eCollection 2016 Sep.

15.

Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.

De Beuckelaer A, Pollard C, Van Lint S, Roose K, Van Hoecke L, Naessens T, Udhayakumar VK, Smet M, Sanders N, Lienenklaus S, Saelens X, Weiss S, Vanham G, Grooten J, De Koker S.

Mol Ther. 2016 Nov;24(11):2012-2020. doi: 10.1038/mt.2016.161. Epub 2016 Aug 10.

16.

Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.

Lambricht L, Vanvarenberg K, De Beuckelaer A, Van Hoecke L, Grooten J, Ucakar B, Lipnik P, Sanders NN, Lienenklaus S, Préat V, Vandermeulen G.

Mol Ther. 2016 Sep;24(9):1686-96. doi: 10.1038/mt.2016.122. Epub 2016 Jun 20.

17.

Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity.

Smet M, Pollard C, De Beuckelaer A, Van Hoecke L, Vander Beken S, De Koker S, Al Dulayymi JR, Huygen K, Verschoor J, Baird MS, Grooten J.

Eur J Immunol. 2016 Sep;46(9):2149-54. doi: 10.1002/eji.201646357. Epub 2016 Jul 29.

18.

GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation.

Naessens T, Schepens B, Smet M, Pollard C, Van Hoecke L, De Beuckelaer A, Willart M, Lambrecht B, De Koker S, Saelens X, Grooten J.

J Allergy Clin Immunol. 2016 Mar;137(3):700-9.e9. doi: 10.1016/j.jaci.2015.09.031. Epub 2015 Nov 10.

PMID:
26560044

Supplemental Content

Loading ...
Support Center