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Items: 13

1.

DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer.

Galle E, Thienpont B, Cappuyns S, Venken T, Busschaert P, Van Haele M, Van Cutsem E, Roskams T, van Pelt J, Verslype C, Dekervel J, Lambrechts D.

Clin Epigenetics. 2020 Feb 14;12(1):27. doi: 10.1186/s13148-020-0821-z.

2.

Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation.

Lo Re O, Mazza T, Giallongo S, Sanna P, Rappa F, Vinh Luong T, Li Volti G, Drovakova A, Roskams T, Van Haele M, Tsochatzis E, Vinciguerra M.

Theranostics. 2020 Jan 1;10(2):910-924. doi: 10.7150/thno.35045. eCollection 2020.

3.

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.

Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G.

Science. 2019 Nov 22;366(6468):1029-1034. doi: 10.1126/science.aaw9886.

PMID:
31754005
4.

Rapid clinical mutational testing of KRAS, BRAF and EGFR: a prospective comparative analysis of the Idylla technique with high-throughput next-generation sequencing.

Van Haele M, Vander Borght S, Ceulemans A, Wieërs M, Metsu S, Sagaert X, Weynand B.

J Clin Pathol. 2020 Jan;73(1):35-41. doi: 10.1136/jclinpath-2019-205970. Epub 2019 Jul 11.

PMID:
31296605
5.

Human Liver Regeneration: An Etiology Dependent Process.

Van Haele M, Snoeck J, Roskams T.

Int J Mol Sci. 2019 May 10;20(9). pii: E2332. doi: 10.3390/ijms20092332. Review.

6.

YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role.

Van Haele M, Moya IM, Karaman R, Rens G, Snoeck J, Govaere O, Nevens F, Verslype C, Topal B, Monbaliu D, Halder G, Roskams T.

Int J Mol Sci. 2019 Feb 1;20(3). pii: E638. doi: 10.3390/ijms20030638.

7.

High-throughput sequencing identifies aetiology-dependent differences in ductular reaction in human chronic liver disease.

Govaere O, Cockell S, Van Haele M, Wouters J, Van Delm W, Van den Eynde K, Bianchi A, van Eijsden R, Van Steenbergen W, Monbaliu D, Nevens F, Roskams T.

J Pathol. 2019 May;248(1):66-76. doi: 10.1002/path.5228. Epub 2019 Jan 30.

PMID:
30584802
8.

Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity.

Korf H, du Plessis J, van Pelt J, De Groote S, Cassiman D, Verbeke L, Ghesquière B, Fendt SM, Bird MJ, Talebi A, Van Haele M, Feio-Azevedo R, Meelberghs L, Roskams T, Mookerjee RP, Mehta G, Jalan R, Gustot T, Laleman W, Nevens F, van der Merwe SW.

Gut. 2019 Oct;68(10):1872-1883. doi: 10.1136/gutjnl-2018-316888. Epub 2018 Dec 22.

PMID:
30580251
9.

CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer.

Benkheil M, Van Haele M, Roskams T, Laporte M, Noppen S, Abbasi K, Delang L, Neyts J, Liekens S.

Exp Cell Res. 2018 Nov 15;372(2):168-177. doi: 10.1016/j.yexcr.2018.09.023. Epub 2018 Oct 2.

PMID:
30287142
10.

HCV-induced EGFR-ERK signaling promotes a pro-inflammatory and pro-angiogenic signature contributing to liver cancer pathogenesis.

Benkheil M, Paeshuyse J, Neyts J, Van Haele M, Roskams T, Liekens S.

Biochem Pharmacol. 2018 Sep;155:305-315. doi: 10.1016/j.bcp.2018.07.011. Epub 2018 Jul 21.

PMID:
30012461
11.

RNA-sequencing-based comparative analysis of human hepatic progenitor cells and their niche from alcoholic steatohepatitis livers.

Ceulemans A, Verhulst S, Van Haele M, Govaere O, Ventura JJ, van Grunsven LA, Roskams T.

Cell Death Dis. 2017 Nov 2;8(11):e3164. doi: 10.1038/cddis.2017.543.

12.

Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma.

Lo Re O, Fusilli C, Rappa F, Van Haele M, Douet J, Pindjakova J, Rocha SW, Pata I, Valčíková B, Uldrijan S, Yeung RS, Peixoto CA, Roskams T, Buschbeck M, Mazza T, Vinciguerra M.

Hepatology. 2018 Feb;67(2):636-650. doi: 10.1002/hep.29519. Epub 2018 Jan 2.

PMID:
28913935
13.

Hepatic Progenitor Cells: An Update.

Van Haele M, Roskams T.

Gastroenterol Clin North Am. 2017 Jun;46(2):409-420. doi: 10.1016/j.gtc.2017.01.011. Review.

PMID:
28506372

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