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Items: 13

1.

A Computational Pipeline for the Diagnosis of CVID Patients.

Emmaneel A, Bogaert DJ, Van Gassen S, Tavernier SJ, Dullaers M, Haerynck F, Saeys Y.

Front Immunol. 2019 Aug 30;10:2009. doi: 10.3389/fimmu.2019.02009. eCollection 2019.

2.

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.

Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN.

J Allergy Clin Immunol. 2019 Jul 20. pii: S0091-6749(19)30943-1. doi: 10.1016/j.jaci.2019.06.041. [Epub ahead of print]

PMID:
31330218
3.

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients.

Venken K, Jacques P, Mortier C, Labadia ME, Decruy T, Coudenys J, Hoyt K, Wayne AL, Hughes R, Turner M, Van Gassen S, Martens L, Smith D, Harcken C, Wahle J, Wang CT, Verheugen E, Schryvers N, Varkas G, Cypers H, Wittoek R, Piette Y, Gyselbrecht L, Van Calenbergh S, Van den Bosch F, Saeys Y, Nabozny G, Elewaut D.

Nat Commun. 2019 Jan 2;10(1):9. doi: 10.1038/s41467-018-07911-6.

4.

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.

Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB.

Nat Commun. 2018 Dec 17;9(1):5340. doi: 10.1038/s41467-018-07758-x.

5.

Myeloid cell heterogeneity in cancer: not a single cell alike.

Kiss M, Van Gassen S, Movahedi K, Saeys Y, Laoui D.

Cell Immunol. 2018 Aug;330:188-201. doi: 10.1016/j.cellimm.2018.02.008. Epub 2018 Feb 14. Review.

PMID:
29482836
6.

Response to Orlova et al. "Science not art: statistically sound methods for identifying subsets in multi-dimensional flow and mass cytometry data sets".

Saeys Y, Van Gassen S, Lambrecht B.

Nat Rev Immunol. 2017 Dec 22;18(1):78. doi: 10.1038/nri.2017.151. No abstract available.

PMID:
29269765
7.

An immune clock of human pregnancy.

Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, El-Sayed YY, Quaintance C, Gibbs R, Darmstadt GL, Shaw GM, Stevenson DK, Tibshirani R, Nolan GP, Lewis DB, Angst MS, Gaudilliere B.

Sci Immunol. 2017 Sep 1;2(15). pii: eaan2946. doi: 10.1126/sciimmunol.aan2946.

8.

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.

Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GHL, Chung TJK, Chan DKH, Tan KK, Hon TLK, Fossum E, Bogen B, Choolani M, Chan JKY, Larbi A, Luche H, Henri S, Saeys Y, Newell EW, Lambrecht BN, Malissen B, Ginhoux F.

Immunity. 2016 Sep 20;45(3):669-684. doi: 10.1016/j.immuni.2016.08.015. Epub 2016 Sep 13.

9.

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.

Sichien D, Scott CL, Martens L, Vanderkerken M, Van Gassen S, Plantinga M, Joeris T, De Prijck S, Vanhoutte L, Vanheerswynghels M, Van Isterdael G, Toussaint W, Madeira FB, Vergote K, Agace WW, Clausen BE, Hammad H, Dalod M, Saeys Y, Lambrecht BN, Guilliams M.

Immunity. 2016 Sep 20;45(3):626-640. doi: 10.1016/j.immuni.2016.08.013. Epub 2016 Sep 13.

10.

Computational flow cytometry: helping to make sense of high-dimensional immunology data.

Saeys Y, Van Gassen S, Lambrecht BN.

Nat Rev Immunol. 2016 Jul;16(7):449-62. doi: 10.1038/nri.2016.56. Epub 2016 Jun 20. Review.

PMID:
27320317
11.

A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes.

Aghaeepour N, Chattopadhyay P, Chikina M, Dhaene T, Van Gassen S, Kursa M, Lambrecht BN, Malek M, McLachlan GJ, Qian Y, Qiu P, Saeys Y, Stanton R, Tong D, Vens C, Walkowiak S, Wang K, Finak G, Gottardo R, Mosmann T, Nolan GP, Scheuermann RH, Brinkman RR.

Cytometry A. 2016 Jan;89(1):16-21. doi: 10.1002/cyto.a.22732. Epub 2015 Oct 8.

12.

FloReMi: Flow density survival regression using minimal feature redundancy.

Van Gassen S, Vens C, Dhaene T, Lambrecht BN, Saeys Y.

Cytometry A. 2016 Jan;89(1):22-9. doi: 10.1002/cyto.a.22734. Epub 2015 Aug 4.

13.

FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data.

Van Gassen S, Callebaut B, Van Helden MJ, Lambrecht BN, Demeester P, Dhaene T, Saeys Y.

Cytometry A. 2015 Jul;87(7):636-45. doi: 10.1002/cyto.a.22625. Epub 2015 Jan 8.

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