Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1.

Verbinnen I, Boens S, Ferreira M, Szekér K, Van Wijk L, Van Eynde A, Bollen M.

Oncogenesis. 2020 Mar 2;9(3):30. doi: 10.1038/s41389-020-0214-3.

2.

Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation.

Verbinnen I, Jonkhout M, Liakath-Ali K, Szekér K, Ferreira M, Boens S, Rouget R, Nikolic M, Schlenner S, Van Eynde A, Bollen M.

J Invest Dermatol. 2020 Jan 21. pii: S0022-202X(20)30035-X. doi: 10.1016/j.jid.2020.01.008. [Epub ahead of print]

PMID:
31972250
3.

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JTM, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2018 Nov 30;38(6). pii: BSR-20150194_COR. doi: 10.1042/BSR-20150194_COR. Print 2018 Dec 21. No abstract available.

4.

The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2.

Ferreira M, Verbinnen I, Fardilha M, Van Eynde A, Bollen M.

J Biol Chem. 2018 Nov 23;293(47):18031-18039. doi: 10.1074/jbc.AC118.005577. Epub 2018 Oct 10.

5.

A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions.

Wu D, De Wever V, Derua R, Winkler C, Beullens M, Van Eynde A, Bollen M.

J Biol Chem. 2018 Sep 28;293(39):15152-15162. doi: 10.1074/jbc.RA118.004132. Epub 2018 Aug 16.

6.

Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.

Ferreira M, Beullens M, Bollen M, Van Eynde A.

Biochim Biophys Acta Mol Cell Res. 2019 Jan;1866(1):16-30. doi: 10.1016/j.bbamcr.2018.07.019. Epub 2018 Jul 26. Review.

7.

Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks.

Winkler C, Rouget R, Wu D, Beullens M, Van Eynde A, Bollen M.

J Cell Sci. 2018 Jul 9;131(13). pii: jcs214932. doi: 10.1242/jcs.214932.

8.

The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis.

Ferreira M, Boens S, Winkler C, Szekér K, Verbinnen I, Van Eynde A, Fardilha M, Bollen M.

Sci Rep. 2017 Oct 17;7(1):13364. doi: 10.1038/s41598-017-13809-y.

9.

Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.

Kig C, Beullens M, Beke L, Van Eynde A, Linders JT, Brehmer D, Bollen M.

J Biol Chem. 2017 Aug 4;292(31):12786. doi: 10.1074/jbc.A113.471433. No abstract available.

10.

Split-BioID: a proximity biotinylation assay for dimerization-dependent protein interactions.

De Munter S, Görnemann J, Derua R, Lesage B, Qian J, Heroes E, Waelkens E, Van Eynde A, Beullens M, Bollen M.

FEBS Lett. 2017 Jan;591(2):415-424. doi: 10.1002/1873-3468.12548. Epub 2017 Jan 12.

11.

Brief Report: The Deletion of the Phosphatase Regulator NIPP1 Causes Progenitor Cell Expansion in the Adult Liver.

Boens S, Verbinnen I, Verhulst S, Szekér K, Ferreira M, Gevaert T, Baes M, Roskams T, van Grunsven LA, Van Eynde A, Bollen M.

Stem Cells. 2016 Aug;34(8):2256-62. doi: 10.1002/stem.2375. Epub 2016 Jun 20.

12.

The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth.

Winkler C, De Munter S, Van Dessel N, Lesage B, Heroes E, Boens S, Beullens M, Van Eynde A, Bollen M.

J Cell Sci. 2015 Dec 15;128(24):4526-37. doi: 10.1242/jcs.175588. Epub 2015 Nov 5.

13.

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JT, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2015 Oct 2;35(6). pii: e00267. doi: 10.1042/BSR20150194. Erratum in: Biosci Rep. 2018 Nov 30;38(6):.

14.

DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate Cancer.

Litovkin K, Van Eynde A, Joniau S, Lerut E, Laenen A, Gevaert T, Gevaert O, Spahn M, Kneitz B, Gramme P, Helleputte T, Isebaert S, Haustermans K, Bollen M.

PLoS One. 2015 Jun 18;10(6):e0130651. doi: 10.1371/journal.pone.0130651. eCollection 2015.

15.

Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits.

Verheyen T, Görnemann J, Verbinnen I, Boens S, Beullens M, Van Eynde A, Bollen M.

Nucleic Acids Res. 2015 Jul 13;43(12):5771-84. doi: 10.1093/nar/gkv500. Epub 2015 May 18.

16.

Protein phosphatase PP1-NIPP1 activates mesenchymal genes in HeLa cells.

Van Dessel N, Boens S, Lesage B, Winkler C, Görnemann J, Van Eynde A, Bollen M.

FEBS Lett. 2015 May 22;589(12):1314-21. doi: 10.1016/j.febslet.2015.04.017. Epub 2015 Apr 20.

17.

Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer.

Litovkin K, Joniau S, Lerut E, Laenen A, Gevaert O, Spahn M, Kneitz B, Isebaert S, Haustermans K, Beullens M, Van Eynde A, Bollen M.

J Cancer Res Clin Oncol. 2014 Nov;140(11):1849-61. doi: 10.1007/s00432-014-1738-8. Epub 2014 Jun 18.

PMID:
24938434
18.

Interactor-guided dephosphorylation by protein phosphatase-1.

Boens S, Szekér K, Van Eynde A, Bollen M.

Methods Mol Biol. 2013;1053:271-81. doi: 10.1007/978-1-62703-562-0_16. Review.

PMID:
23860659
19.

Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.

Kig C, Beullens M, Beke L, Van Eynde A, Linders JT, Brehmer D, Bollen M.

J Biol Chem. 2013 Aug 16;288(33):24200-12. doi: 10.1074/jbc.M113.471433. Epub 2013 Jul 8. Retraction in: J Biol Chem. 2017 Aug 4;292(31):12786.

20.

NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes.

Minnebo N, Görnemann J, O'Connell N, Van Dessel N, Derua R, Vermunt MW, Page R, Beullens M, Peti W, Van Eynde A, Bollen M.

Nucleic Acids Res. 2013 Jan;41(2):842-54. doi: 10.1093/nar/gks1255. Epub 2012 Dec 13.

21.

A role for PP1/NIPP1 in steering migration of human cancer cells.

Martin-Granados C, Prescott AR, Van Dessel N, Van Eynde A, Arocena M, Klaska IP, Görnemann J, Beullens M, Bollen M, Forrester JV, McCaig CD.

PLoS One. 2012;7(7):e40769. doi: 10.1371/journal.pone.0040769. Epub 2012 Jul 16.

22.

PP1/Repo-man dephosphorylates mitotic histone H3 at T3 and regulates chromosomal aurora B targeting.

Qian J, Lesage B, Beullens M, Van Eynde A, Bollen M.

Curr Biol. 2011 May 10;21(9):766-73. doi: 10.1016/j.cub.2011.03.047. Epub 2011 Apr 21.

23.

Growth inhibition properties of the putative prostate cancer biomarkers PSP94 and CRISP-3.

Van Eynde A, Litovkin K, Bollen M.

Asian J Androl. 2011 Mar;13(2):205-6. doi: 10.1038/aja.2010.120. Epub 2010 Nov 22. No abstract available. Erratum in: Asian J Androl. 2011 Mar;13(2):348.

24.

Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription.

Ammosova T, Yedavalli VR, Niu X, Jerebtsova M, Van Eynde A, Beullens M, Bollen M, Jeang KT, Nekhai S.

J Biol Chem. 2011 Feb 4;286(5):3798-804. doi: 10.1074/jbc.M110.196493. Epub 2010 Nov 22.

25.

The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets.

Van Dessel N, Beke L, Görnemann J, Minnebo N, Beullens M, Tanuma N, Shima H, Van Eynde A, Bollen M.

Nucleic Acids Res. 2010 Nov;38(21):7500-12. doi: 10.1093/nar/gkq643. Epub 2010 Jul 29.

26.

Docking motif-guided mapping of the interactome of protein phosphatase-1.

Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A, Nicolaescu E, Lesage B, Bollen M.

Chem Biol. 2009 Apr 24;16(4):365-71. doi: 10.1016/j.chembiol.2009.02.012.

27.

The transcriptional repression by NIPP1 is mediated by Polycomb group proteins.

Roy N, Van Eynde A, Beke L, Nuytten M, Bollen M.

Biochim Biophys Acta. 2007 Sep-Oct;1769(9-10):541-5. Epub 2007 Aug 8.

PMID:
17804093
28.

The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing.

Nuytten M, Beke L, Van Eynde A, Ceulemans H, Beullens M, Van Hummelen P, Fuks F, Bollen M.

Oncogene. 2008 Feb 28;27(10):1449-60. Epub 2007 Sep 3.

PMID:
17724462
29.

The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2.

Beke L, Nuytten M, Van Eynde A, Beullens M, Bollen M.

Oncogene. 2007 Jul 5;26(31):4590-5. Epub 2007 Jan 22.

PMID:
17237810
30.

The KH-Tudor domain of a-kinase anchoring protein 149 mediates RNA-dependent self-association.

Rogne M, Landsverk HB, Van Eynde A, Beullens M, Bollen M, Collas P, Küntziger T.

Biochemistry. 2006 Dec 19;45(50):14980-9.

PMID:
17154535
31.

The translation initiation factor eIF2beta is an interactor of protein phosphatase-1.

Wakula P, Beullens M, van Eynde A, Ceulemans H, Stalmans W, Bollen M.

Biochem J. 2006 Dec 1;400(2):377-83.

32.

The Polycomb group protein EZH2 directly controls DNA methylation.

Viré E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C, Morey L, Van Eynde A, Bernard D, Vanderwinden JM, Bollen M, Esteller M, Di Croce L, de Launoit Y, Fuks F.

Nature. 2006 Feb 16;439(7078):871-4. Epub 2005 Dec 14. Erratum in: Nature. 2007 Apr 12;446(7137):824.

PMID:
16357870
33.

Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D.

Jansen S, Stefan C, Creemers JW, Waelkens E, Van Eynde A, Stalmans W, Bollen M.

J Cell Sci. 2005 Jul 15;118(Pt 14):3081-9. Epub 2005 Jun 28.

34.

Interactor-mediated nuclear translocation and retention of protein phosphatase-1.

Lesage B, Beullens M, Nuytten M, Van Eynde A, Keppens S, Himpens B, Bollen M.

J Biol Chem. 2004 Dec 31;279(53):55978-84. Epub 2004 Oct 22.

35.

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation.

Van Eynde A, Nuytten M, Dewerchin M, Schoonjans L, Keppens S, Beullens M, Moons L, Carmeliet P, Stalmans W, Bollen M.

Mol Cell Biol. 2004 Jul;24(13):5863-74.

36.

Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1.

Vulsteke V, Beullens M, Boudrez A, Keppens S, Van Eynde A, Rider MH, Stalmans W, Bollen M.

J Biol Chem. 2004 Mar 5;279(10):8642-7. Epub 2003 Dec 29.

37.

Validation of interactions with protein phosphatase-1.

Van Eynde A, Bollen M.

Methods Enzymol. 2003;366:144-56. No abstract available.

PMID:
14674247
38.
39.
40.

Nuclear and subnuclear targeting sequences of the protein phosphatase-1 regulator NIPP1.

Jagiello I, Van Eynde A, Vulsteke V, Beullens M, Boudrez A, Keppens S, Stalmans W, Bollen M.

J Cell Sci. 2000 Nov;113 Pt 21:3761-8.

41.

NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry.

Boudrez A, Beullens M, Groenen P, Van Eynde A, Vulsteke V, Jagiello I, Murray M, Krainer AR, Stalmans W, Bollen M.

J Biol Chem. 2000 Aug 18;275(33):25411-7.

42.

Mapping of the RNA-binding and endoribonuclease domains of NIPP1, a nuclear targeting subunit of protein phosphatase 1.

Jin Q, Beullens M, Jagiello I, Van Eynde A, Vulsteke V, Stalmans W, Bollen M.

Biochem J. 1999 Aug 15;342 ( Pt 1):13-9.

43.

Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1.

Beullens M, Van Eynde A, Vulsteke V, Connor J, Shenolikar S, Stalmans W, Bollen M.

J Biol Chem. 1999 May 14;274(20):14053-61.

44.

Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1.

Ceulemans H, Van Eynde A, Pérez-Callejón E, Beullens M, Stalmans W, Bollen M.

Eur J Biochem. 1999 May;262(1):36-42.

45.

Organization and alternate splice products of the gene encoding nuclear inhibitor of protein phosphatase-1 (NIPP-1).

Van Eynde A, Pérez-Callejón E, Schoenmakers E, Jacquemin M, Stalmans W, Bollen M.

Eur J Biochem. 1999 Apr;261(1):291-300.

46.

Inhibition of translation by mRNA encoding NIPP-1, a nuclear inhibitor of protein phosphatase-1.

Wera S, Van Eynde A, Stalmans W, Bollen M.

Eur J Biochem. 1997 Jul 1;247(1):411-5.

47.

Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing.

Van Eynde A, Wera S, Beullens M, Torrekens S, Van Leuven F, Stalmans W, Bollen M.

J Biol Chem. 1995 Nov 24;270(47):28068-74.

48.

Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase-1.

Renouf S, Beullens M, Wera S, Van Eynde A, Sikela J, Stalmans W, Bollen M.

FEBS Lett. 1995 Nov 13;375(1-2):75-8.

49.

Full activation of a nuclear species of protein phosphatase-1 by phosphorylation with protein kinase A and casein kinase-2.

Van Eynde A, Beullens M, Stalmans W, Bollen M.

Biochem J. 1994 Feb 1;297 ( Pt 3):447-9. Erratum in: Biochem J 1994 May 1;299(Pt 3):903.

50.

Inactivation of nuclear inhibitory polypeptides of protein phosphatase-1 (NIPP-1) by protein kinase A.

Beullens M, Van Eynde A, Bollen M, Stalmans W.

J Biol Chem. 1993 Jun 25;268(18):13172-7.

Supplemental Content

Loading ...
Support Center