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Items: 16


Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.

Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, Garner B, Ittner A, Karl T, Don AS.

J Neurosci. 2019 Nov 27;39(48):9645-9659. doi: 10.1523/JNEUROSCI.0524-19.2019. Epub 2019 Oct 22.


Development and initial validation of the job loss grief scale.

van Eersel JHW, Taris TW, Boelen PA.

Anxiety Stress Coping. 2019 Jul;32(4):428-442. doi: 10.1080/10615806.2019.1619703. Epub 2019 May 19.


Tau exacerbates excitotoxic brain damage in an animal model of stroke.

Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, van der Hoven J, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, Housley GD, Klugmann M, Ke YD, Ittner LM.

Nat Commun. 2017 Sep 7;8(1):473. doi: 10.1038/s41467-017-00618-0.


Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology.

Ahmed RM, Irish M, van Eersel J, Ittner A, Ke YD, Volkerling A, van der Hoven J, Tanaka K, Karl T, Kassiou M, Kril JJ, Piguet O, Götz J, Kiernan MC, Halliday GM, Hodges JR, Ittner LM.

Neurosci Biobehav Rev. 2017 Mar;74(Pt A):126-138. doi: 10.1016/j.neubiorev.2017.01.004. Epub 2017 Jan 11. Review.


The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons.

Chua SW, Cornejo A, van Eersel J, Stevens CH, Vaca I, Cueto M, Kassiou M, Gladbach A, Macmillan A, Lewis L, Whan R, Ittner LM.

ACS Chem Neurosci. 2017 Apr 19;8(4):743-751. doi: 10.1021/acschemneuro.6b00433. Epub 2017 Jan 12.


Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration.

van Eersel J, Stevens CH, Przybyla M, Gladbach A, Stefanoska K, Chan CK, Ong WY, Hodges JR, Sutherland GT, Kril JJ, Abramowski D, Staufenbiel M, Halliday GM, Ittner LM.

Neuropathol Appl Neurobiol. 2015 Dec;41(7):906-25. doi: 10.1111/nan.12233. Epub 2015 May 30.


The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo.

Ittner AA, Bertz J, Chan TY, van Eersel J, Polly P, Ittner LM.

Diabetologia. 2014 Jul;57(7):1410-9. doi: 10.1007/s00125-014-3230-z. Epub 2014 Apr 15.


ERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke.

Gladbach A, van Eersel J, Bi M, Ke YD, Ittner LM.

J Neural Transm (Vienna). 2014 May;121(5):543-7. doi: 10.1007/s00702-013-1138-2. Epub 2013 Dec 14.


Lessons from tau-deficient mice.

Ke YD, Suchowerska AK, van der Hoven J, De Silva DM, Wu CW, van Eersel J, Ittner A, Ittner LM.

Int J Alzheimers Dis. 2012;2012:873270. doi: 10.1155/2012/873270. Epub 2012 Jun 6.


Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.

van Eersel J, Ke YD, Gladbach A, Bi M, Götz J, Kril JJ, Ittner LM.

PLoS One. 2011;6(7):e22850. doi: 10.1371/journal.pone.0022850. Epub 2011 Jul 29.


Brief update on different roles of tau in neurodegeneration.

Ittner A, Ke YD, van Eersel J, Gladbach A, Götz J, Ittner LM.

IUBMB Life. 2011 Jul;63(7):495-502. doi: 10.1002/iub.467. Review.


Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.

Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, Wölfing H, Chieng BC, Christie MJ, Napier IA, Eckert A, Staufenbiel M, Hardeman E, Götz J.

Cell. 2010 Aug 6;142(3):387-97. doi: 10.1016/j.cell.2010.06.036. Epub 2010 Jul 22.


Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.

van Eersel J, Ke YD, Liu X, Delerue F, Kril JJ, Götz J, Ittner LM.

Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13888-93. doi: 10.1073/pnas.1009038107. Epub 2010 Jul 19.


Animal models reveal role for tau phosphorylation in human disease.

Götz J, Gladbach A, Pennanen L, van Eersel J, Schild A, David D, Ittner LM.

Biochim Biophys Acta. 2010 Oct;1802(10):860-71. doi: 10.1016/j.bbadis.2009.09.008. Epub 2009 Sep 12. Review.


Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains.

van Eersel J, Bi M, Ke YD, Hodges JR, Xuereb JH, Gregory GC, Halliday GM, Götz J, Kril JJ, Ittner LM.

J Neural Transm (Vienna). 2009 Oct;116(10):1243-51. doi: 10.1007/s00702-009-0293-y. Epub 2009 Aug 20.


Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia.

Ittner LM, Fath T, Ke YD, Bi M, van Eersel J, Li KM, Gunning P, Götz J.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15997-6002. doi: 10.1073/pnas.0808084105. Epub 2008 Oct 2.

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