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Items: 19

1.

Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.

Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2018 Apr;10(4). pii: e8300. doi: 10.15252/emmm.201708300.

2.

The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection.

Gorlé N, Blaecher C, Bauwens E, Vandendriessche C, Balusu S, Vandewalle J, Van Cauwenberghe C, Van Wonterghem E, Van Imschoot G, Liu C, Ducatelle R, Libert C, Haesebrouck F, Smet A, Vandenbroucke RE.

Brain Behav Immun. 2018 Mar;69:35-47. doi: 10.1016/j.bbi.2017.12.010. Epub 2017 Dec 16.

PMID:
29258921
3.

Lymphoblast-derived integration-free iPSC lines from a female and male Alzheimer's disease patient expressing different copy numbers of a coding CNV in the Alzheimer risk gene CR1.

Schröter F, Sleegers K, Van Cauwenberghe C, Bohndorf M, Wruck W, Van Broeckhoven C, Adjaye J.

Stem Cell Res. 2016 Nov;17(3):560-563. doi: 10.1016/j.scr.2016.10.003. Epub 2016 Oct 19.

4.

Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.

Van Cauwenberghe C, Vandendriessche C, Libert C, Vandenbroucke RE.

Mamm Genome. 2016 Aug;27(7-8):300-19. doi: 10.1007/s00335-016-9647-6. Epub 2016 May 30. Review.

PMID:
27240590
5.

The effect of aging on brain barriers and the consequences for Alzheimer's disease development.

Gorlé N, Van Cauwenberghe C, Libert C, Vandenbroucke RE.

Mamm Genome. 2016 Aug;27(7-8):407-20. doi: 10.1007/s00335-016-9637-8. Epub 2016 May 3. Review.

PMID:
27143113
6.

Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation.

Van den Bossche T, Sleegers K, Cuyvers E, Engelborghs S, Sieben A, De Roeck A, Van Cauwenberghe C, Vermeulen S, Van den Broeck M, Laureys A, Peeters K, Mattheijssens M, Vandenbulcke M, Vandenberghe R, Martin JJ, De Deyn PP, Cras P, Van Broeckhoven C; Belgian Neurology Consortium.

Neurology. 2016 Jun 7;86(23):2126-33. doi: 10.1212/WNL.0000000000002628. Epub 2016 Apr 1.

7.

The genetic landscape of Alzheimer disease: clinical implications and perspectives.

Van Cauwenberghe C, Van Broeckhoven C, Sleegers K.

Genet Med. 2016 May;18(5):421-30. doi: 10.1038/gim.2015.117. Epub 2015 Aug 27. Review.

8.

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations.

Bettens K, Vermeulen S, Van Cauwenberghe C, Heeman B, Asselbergh B, Robberecht C, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, Sleegers K.

Mol Neurodegener. 2015 Jul 16;10:30. doi: 10.1186/s13024-015-0024-9.

9.

Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study.

Cuyvers E, De Roeck A, Van den Bossche T, Van Cauwenberghe C, Bettens K, Vermeulen S, Mattheijssens M, Peeters K, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K.

Lancet Neurol. 2015 Aug;14(8):814-822. doi: 10.1016/S1474-4422(15)00133-7. Epub 2015 Jun 30.

PMID:
26141617
10.

A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42.

Sleegers K, Bettens K, De Roeck A, Van Cauwenberghe C, Cuyvers E, Verheijen J, Struyfs H, Van Dongen J, Vermeulen S, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C; BELNEU consortium.

Alzheimers Dement. 2015 Dec;11(12):1452-1460. doi: 10.1016/j.jalz.2015.02.013. Epub 2015 Jun 15.

11.

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

Jansen MP, Sas L, Sieuwerts AM, Van Cauwenberghe C, Ramirez-Ardila D, Look M, Ruigrok-Ritstier K, Finetti P, Bertucci F, Timmermans MM, van Deurzen CH, Martens JW, Simon I, Roepman P, Linn SC, van Dam P, Kok M, Lardon F, Vermeulen PB, Foekens JA, Dirix L, Berns EM, Van Laere S.

Mol Oncol. 2015 Jun;9(6):1218-33. doi: 10.1016/j.molonc.2015.02.006. Epub 2015 Mar 4.

12.

Complement receptor 1 coding variant p.Ser1610Thr in Alzheimer's disease and related endophenotypes.

Van Cauwenberghe C, Bettens K, Engelborghs S, Vandenbulcke M, Van Dongen J, Vermeulen S, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K.

Neurobiol Aging. 2013 Sep;34(9):2235.e1-6. doi: 10.1016/j.neurobiolaging.2013.03.008. Epub 2013 Apr 10.

PMID:
23582656
13.

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, Zommer N, Hamdane M, Bellenguez C, Dartigues JF, Hauw JJ, Letronne F, Ayral AM, Sleegers K, Schellens A, Broeck LV, Engelborghs S, De Deyn PP, Vandenberghe R, O'Donovan M, Owen M, Epelbaum J, Mercken M, Karran E, Bantscheff M, Drewes G, Joberty G, Campion D, Octave JN, Berr C, Lathrop M, Callaerts P, Mann D, Williams J, Buée L, Dewachter I, Van Broeckhoven C, Amouyel P, Moechars D, Dermaut B, Lambert JC; GERAD consortium.

Mol Psychiatry. 2013 Nov;18(11):1225-34. doi: 10.1038/mp.2013.1. Epub 2013 Feb 12.

14.

C9orf72 G4C2 repeat expansions in Alzheimer's disease and mild cognitive impairment.

Cacace R, Van Cauwenberghe C, Bettens K, Gijselinck I, van der Zee J, Engelborghs S, Vandenbulcke M, Van Dongen J, Bäumer V, Dillen L, Mattheijssens M, Peeters K, Cruts M, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K.

Neurobiol Aging. 2013 Jun;34(6):1712.e1-7. doi: 10.1016/j.neurobiolaging.2012.12.019. Epub 2013 Jan 24.

PMID:
23352322
15.

Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism.

Hazrati LN, Van Cauwenberghe C, Brooks PL, Brouwers N, Ghani M, Sato C, Cruts M, Sleegers K, St George-Hyslop P, Van Broeckhoven C, Rogaeva E.

Neurobiol Aging. 2012 Dec;33(12):2949.e5-2949.e12. doi: 10.1016/j.neurobiolaging.2012.07.001. Epub 2012 Jul 21.

PMID:
22819390
16.

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.

Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O'Donovan M, Valdivieso F, Caffarra P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P.

Mol Psychiatry. 2013 Apr;18(4):461-70. doi: 10.1038/mp.2012.14. Epub 2012 Mar 20. Erratum in: Mol Psychiatry. 2013 Apr;18(4):521. Caffara, P [corrected to Caffarra, P].

17.

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

Gijselinck I, Van Langenhove T, van der Zee J, Sleegers K, Philtjens S, Kleinberger G, Janssens J, Bettens K, Van Cauwenberghe C, Pereson S, Engelborghs S, Sieben A, De Jonghe P, Vandenberghe R, Santens P, De Bleecker J, Maes G, Bäumer V, Dillen L, Joris G, Cuijt I, Corsmit E, Elinck E, Van Dongen J, Vermeulen S, Van den Broeck M, Vaerenberg C, Mattheijssens M, Peeters K, Robberecht W, Cras P, Martin JJ, De Deyn PP, Cruts M, Van Broeckhoven C.

Lancet Neurol. 2012 Jan;11(1):54-65. doi: 10.1016/S1474-4422(11)70261-7. Epub 2011 Dec 7. Erratum in: Lancet Neurol. 2012 Feb;11(2):125.

PMID:
22154785
18.

Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.

Brouwers N, Van Cauwenberghe C, Engelborghs S, Lambert JC, Bettens K, Le Bastard N, Pasquier F, Montoya AG, Peeters K, Mattheijssens M, Vandenberghe R, Deyn PP, Cruts M, Amouyel P, Sleegers K, Van Broeckhoven C.

Mol Psychiatry. 2012 Feb;17(2):223-33. doi: 10.1038/mp.2011.24. Epub 2011 Mar 15.

19.

Fractal analysis of amyloid plaques in Alzheimer's disease patients and mouse models.

Pirici D, Van Cauwenberghe C, Van Broeckhoven C, Kumar-Singh S.

Neurobiol Aging. 2011 Sep;32(9):1579-87. doi: 10.1016/j.neurobiolaging.2009.10.010. Epub 2009 Dec 16.

PMID:
20015575

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