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Silent coronary artery disease in asymptomatic patients with severe aortic stenosis and normal exercise testing.

Banovic M, Iung B, Brkovic V, Nikolic S, Mitrovic P, Van Camp G, Penicka M, Simic D, Kockova R, Aleksandric S, Asanin M, Nedeljkovic I, Popovic D, Putnik S, Jaukovic M, Bartunek J.

Coron Artery Dis. 2019 Oct 1. doi: 10.1097/MCA.0000000000000801. [Epub ahead of print]


Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model.

Croes L, Fransen E, Hylebos M, Buys K, Hermans C, Broeckx G, Peeters M, Pauwels P, Op de Beeck K, Van Camp G.

Cancers (Basel). 2019 Aug 20;11(8). pii: E1214. doi: 10.3390/cancers11081214.


Glutamatergic postsynaptic density in early life stress programming: Topographic gene expression of mGlu5 receptors and Homer proteins.

Buonaguro EF, Morley-Fletcher S, Avagliano C, Vellucci L, Iasevoli F, Bouwalerh H, Van Camp G, Nicoletti F, Maccari S, de Bartolomeis A.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Aug 9;96:109725. doi: 10.1016/j.pnpbp.2019.109725. [Epub ahead of print]


Clinical applications of (epi)genetics in gastroenteropancreatic neuroendocrine neoplasms: Moving towards liquid biopsies.

Boons G, Vandamme T, Peeters M, Van Camp G, Op de Beeck K.

Rev Endocr Metab Disord. 2019 Jul 31. doi: 10.1007/s11154-019-09508-w. [Epub ahead of print] Review.


Impact of non-invasive anatomical testing on optimal medical prescription in patients with suspected coronary artery disease.

Devuyst S, Gigase A, Spapen J, Brouwers S, Couck T, Sonck J, Mizukami T, Gigante C, de Raedt H, Schelfaut D, Heggermont W, De Bruyne B, Penicka M, Van Camp G, Collet C.

Cardiovasc Diagn Ther. 2019 Jun;9(3):221-228. doi: 10.21037/cdt.2019.04.10.


Perinatal Stress Programs Sex Differences in the Behavioral and Molecular Chronobiological Profile of Rats Maintained Under a 12-h Light-Dark Cycle.

Morley-Fletcher S, Mairesse J, Van Camp G, Reynaert ML, Gatta E, Marrocco J, Bouwalerh H, Nicoletti F, Maccari S.

Front Mol Neurosci. 2019 May 1;12:89. doi: 10.3389/fnmol.2019.00089. eCollection 2019.


Cardiac Resynchronization Therapy Optimization: A Comprehensive Approach.

Katbeh A, Van Camp G, Barbato E, Galderisi M, Trimarco B, Bartunek J, Vanderheyden M, Penicka M.

Cardiology. 2019;142(2):116-128. doi: 10.1159/000499192. Epub 2019 May 22. Review.


Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer.

Ibrahim J, Op de Beeck K, Fransen E, Croes L, Beyens M, Suls A, Vanden Berghe W, Peeters M, Van Camp G.

Cancer Med. 2019 May;8(5):2133-2145. doi: 10.1002/cam4.2103. Epub 2019 Apr 16.


Insufficient evidence for a role of SERPINF1 in otosclerosis.

Valgaeren H, Sommen M, Beyens M, Vandeweyer G, Schrauwen I, Schepers A, Schatteman I, Topsakal V, Dhooge I, Kunst H, Zanetti D, Huber AM, Hoischen A, Fransen E, Van Camp G.

Mol Genet Genomics. 2019 Aug;294(4):1001-1006. doi: 10.1007/s00438-019-01558-8. Epub 2019 Apr 9.


A systematic review of hearing and vestibular function in carriers of the Pro51Ser mutation in the COCH gene.

JanssensdeVarebeke S, Topsakal V, Van Camp G, Van Rompaey V.

Eur Arch Otorhinolaryngol. 2019 May;276(5):1251-1262. doi: 10.1007/s00405-019-05322-x. Epub 2019 Feb 26.


Giant pseudoaneurysm of the left ventricle.

Gigase A, Spapen J, Penicka M, Van Camp G.

Int J Cardiovasc Imaging. 2019 Jun;35(6):1161-1162. doi: 10.1007/s10554-019-01558-0. Epub 2019 Feb 23. No abstract available.


Imaging of Myocardial Fibrosis and Its Functional Correlates in Aortic Stenosis: A Review and Clinical Potential.

Katbeh A, Ondrus T, Barbato E, Galderisi M, Trimarco B, Van Camp G, Vanderheyden M, Penicka M.

Cardiology. 2018;141(3):141-149. doi: 10.1159/000493164. Epub 2018 Dec 5. Review.


Cell-Free DNA From Metastatic Pancreatic Neuroendocrine Tumor Patients Contains Tumor-Specific Mutations and Copy Number Variations.

Boons G, Vandamme T, Peeters M, Beyens M, Driessen A, Janssens K, Zwaenepoel K, Roeyen G, Van Camp G, Op de Beeck K.

Front Oncol. 2018 Nov 1;8:467. doi: 10.3389/fonc.2018.00467. eCollection 2018.


Variants affecting diverse domains of MEPE are associated with two distinct bone disorders, a craniofacial bone defect and otosclerosis.

Schrauwen I, Valgaeren H, Tomas-Roca L, Sommen M, Altunoglu U, Wesdorp M, Beyens M, Fransen E, Nasir A, Vandeweyer G, Schepers A, Rahmoun M, van Beusekom E, Huentelman MJ, Offeciers E, Dhooghe I, Huber A, Van de Heyning P, Zanetti D, De Leenheer EMR, Gilissen C, Hoischen A, Cremers CW, Verbist B, de Brouwer APM, Padberg GW, Pennings R, Kayserili H, Kremer H, Van Camp G, van Bokhoven H.

Genet Med. 2019 May;21(5):1199-1208. doi: 10.1038/s41436-018-0300-5. Epub 2018 Oct 5.


Tumor-specific genetic variants can be detected in circulating cell-free DNA of malignant pleural mesothelioma patients.

Hylebos M, Op de Beeck K, Pauwels P, Zwaenepoel K, van Meerbeeck JP, Van Camp G.

Lung Cancer. 2018 Oct;124:19-22. doi: 10.1016/j.lungcan.2018.07.028. Epub 2018 Jul 21.


Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway.

Fetoni AR, Zorzi V, Paciello F, Ziraldo G, Peres C, Raspa M, Scavizzi F, Salvatore AM, Crispino G, Tognola G, Gentile G, Spampinato AG, Cuccaro D, Guarnaccia M, Morello G, Van Camp G, Fransen E, Brumat M, Girotto G, Paludetti G, Gasparini P, Cavallaro S, Mammano F.

Redox Biol. 2018 Oct;19:301-317. doi: 10.1016/j.redox.2018.08.002. Epub 2018 Aug 7.


Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms.

Vandamme T, Beyens M, Boons G, Schepers A, Kamp K, Biermann K, Pauwels P, De Herder WW, Hofland LJ, Peeters M, Van Camp G, Op de Beeck K.

Endocr Relat Cancer. 2019 Jan 1;26(1):1-12. doi: 10.1530/ERC-18-0120.


Molecular analysis of an asbestos-exposed Belgian family with a high prevalence of mesothelioma.

Hylebos M, Op de Beeck K, van den Ende J, Pauwels P, Lammens M, van Meerbeeck JP, Van Camp G.

Fam Cancer. 2018 Oct;17(4):569-576. doi: 10.1007/s10689-018-0095-1.


Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.

Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T.

J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25.


Role of Targeted Next Generation Sequencing in the Etiological Work-Up of Congenitally Deaf Children.

Boudewyns A, van den Ende J, Sommen M, Wuyts W, Peeters N, Van de Heyning P, Van Camp G.

Otol Neurotol. 2018 Jul;39(6):732-738. doi: 10.1097/MAO.0000000000001847.


Consequences of a double hit of stress during the perinatal period and midlife in female rats: Mismatch or cumulative effect?

Van Camp G, Cigalotti J, Bouwalerh H, Mairesse J, Gatta E, Palanza P, Maccari S, Morley-Fletcher S.

Psychoneuroendocrinology. 2018 Jul;93:45-55. doi: 10.1016/j.psyneuen.2018.04.004. Epub 2018 Apr 14.


Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer.

Croes L, Beyens M, Fransen E, Ibrahim J, Vanden Berghe W, Suls A, Peeters M, Pauwels P, Van Camp G, Op de Beeck K.

Clin Epigenetics. 2018 Apr 11;10:51. doi: 10.1186/s13148-018-0479-y. eCollection 2018.


GLI2 promoter hypermethylation in saliva of children with a respiratory allergy.

Langie SAS, Moisse M, Szarc Vel Szic K, Van Der Plas E, Koppen G, De Prins S, Louwies T, Nelen V, Van Camp G, Lambrechts D, Schoeters G, Vanden Berghe W, De Boever P.

Clin Epigenetics. 2018 Apr 11;10:50. doi: 10.1186/s13148-018-0484-1. eCollection 2018.


Reduced maternal behavior caused by gestational stress is predictive of life span changes in risk-taking behavior and gene expression due to altering of the stress/anti-stress balance.

Gatta E, Mairesse J, Deruyter L, Marrocco J, Van Camp G, Bouwalerh H, Lo Guidice JM, Morley-Fletcher S, Nicoletti F, Maccari S.

Neurotoxicology. 2018 May;66:138-149. doi: 10.1016/j.neuro.2018.04.005. Epub 2018 Apr 6.


Effect of Primary Tumor Location on Second- or Later-line Treatment Outcomes in Patients With RAS Wild-type Metastatic Colorectal Cancer and All Treatment Lines in Patients With RAS Mutations in Four Randomized Panitumumab Studies.

Boeckx N, Koukakis R, Op de Beeck K, Rolfo C, Van Camp G, Siena S, Tabernero J, Douillard JY, André T, Peeters M.

Clin Colorectal Cancer. 2018 Sep;17(3):170-178.e3. doi: 10.1016/j.clcc.2018.03.005. Epub 2018 Mar 8.


Mutation and Methylation Analysis of Circulating Tumor DNA Can Be Used for Follow-up of Metastatic Colorectal Cancer Patients.

Boeckx N, Op de Beeck K, Beyens M, Deschoolmeester V, Hermans C, De Clercq P, Garrigou S, Normand C, Monsaert E, Papadimitriou K, Laurent-Puig P, Pauwels P, Van Camp G, Taly V, Peeters M.

Clin Colorectal Cancer. 2018 Jun;17(2):e369-e379. doi: 10.1016/j.clcc.2018.02.006. Epub 2018 Feb 22.


The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats.

Morley-Fletcher S, Zuena AR, Mairesse J, Gatta E, Van Camp G, Bouwalerh H, Riozzi B, Battaglia G, Pittaluga A, Olivero G, Mocaer E, Bretin S, Nicoletti F, Maccari S.

Neuropharmacology. 2018 Jun;135:284-296. doi: 10.1016/j.neuropharm.2018.03.018. Epub 2018 Mar 23.


Hemangioma of the mitral valve as a rare, incidental finding in an adult female.

Castelein T, Van Praet F, Van Der Steen K, Van Camp G.

Acta Cardiol. 2019 Apr;74(2):180-181. doi: 10.1080/00015385.2018.1453451. Epub 2018 Mar 20. No abstract available.


Bi-allelic inactivating variants in the COCH gene cause autosomal recessive prelingual hearing impairment.

JanssensdeVarebeke SPF, Van Camp G, Peeters N, Elinck E, Widdershoven J, Cox T, Deben K, Ketelslagers K, Crins T, Wuyts W.

Eur J Hum Genet. 2018 Apr;26(4):587-591. doi: 10.1038/s41431-017-0066-2. Epub 2018 Feb 15.


Resolving Apparent Inconsistencies Between Area, Flow, and Gradient Measurements in Patients With Aortic Valve Stenosis and Preserved Left Ventricular Ejection Fraction.

Mo Y, Penicka M, Di Gioia G, Barbato E, Ondrus T, Vanderheyden M, De Bruyne B, Bartunek J, Van Camp G.

Am J Cardiol. 2018 Mar 15;121(6):751-757. doi: 10.1016/j.amjcard.2017.11.047. Epub 2017 Dec 25.


Large-scale copy number analysis reveals variations in genes not previously associated with malignant pleural mesothelioma.

Hylebos M, Van Camp G, Vandeweyer G, Fransen E, Beyens M, Cornelissen R, Suls A, Pauwels P, van Meerbeeck JP, Op de Beeck K.

Oncotarget. 2017 Dec 1;8(69):113673-113686. doi: 10.18632/oncotarget.22817. eCollection 2017 Dec 26.


A Pilot Study for Left Atrial Appendage Occlusion Guided by 3-Dimensional Rotational Angiography Alone.

De Potter T, Chatzikyriakou S, Silva E, Van Camp G, Penicka M.

JACC Cardiovasc Interv. 2018 Jan 22;11(2):223-224. doi: 10.1016/j.jcin.2017.08.053. No abstract available.


The predictive value of primary tumor location in patients with metastatic colorectal cancer: A systematic review.

Boeckx N, Janssens K, Van Camp G, Rasschaert M, Papadimitriou K, Peeters M, Op de Beeck K.

Crit Rev Oncol Hematol. 2018 Jan;121:1-10. doi: 10.1016/j.critrevonc.2017.11.003. Epub 2017 Nov 7. Review.


Prognostic Implications of Magnetic Resonance-Derived Quantification in Asymptomatic Patients With Organic Mitral Regurgitation: Comparison With Doppler Echocardiography-Derived Integrative Approach.

Penicka M, Vecera J, Mirica DC, Kotrc M, Kockova R, Van Camp G.

Circulation. 2018 Mar 27;137(13):1349-1360. doi: 10.1161/CIRCULATIONAHA.117.029332. Epub 2017 Dec 21.


pyAmpli: an amplicon-based variant filter pipeline for targeted resequencing data.

Beyens M, Boeckx N, Van Camp G, Op de Beeck K, Vandeweyer G.

BMC Bioinformatics. 2017 Dec 14;18(1):554. doi: 10.1186/s12859-017-1985-1.


Summary of 2017 ESC guidelines on valvular heart disease, peripheral artery disease, STEMI and on dual antiplatelet therapy.

Van Camp G, De Backer T, Beauloye C, Desmet W, Claeys MJ.

Acta Cardiol. 2018 Oct;73(5):419-425. doi: 10.1080/00015385.2017.1410352. Epub 2017 Dec 11.


The Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): A protocol update.

Banovic M, Iung B, Bartunek J, Penicka M, Vanderheyden M, Casselman F, van Camp G, Nikolic S, Putnik S.

Am Heart J. 2018 Jan;195:153-154. doi: 10.1016/j.ahj.2017.10.005. Epub 2017 Oct 14. No abstract available.


A new perspective on the genetics of keratoconus: why have we not been more successful?

Valgaeren H, Koppen C, Van Camp G.

Ophthalmic Genet. 2018 Apr;39(2):158-174. doi: 10.1080/13816810.2017.1393831. Epub 2017 Nov 7. Review.


Aortic valve replacement improves survival in severe aortic stenosis with gradient-area mismatch.

Mo Y, Van Camp G, Di Gioia G, Barbato E, Ondrus T, Casselman F, Vanderheyden M, De Bruyne B, Bartunek J, Penicka M.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):569-575. doi: 10.1093/ejcts/ezx362.


MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

Deben C, Op de Beeck K, Van den Bossche J, Jacobs J, Lardon F, Wouters A, Peeters M, Van Camp G, Rolfo C, Deschoolmeester V, Pauwels P.

J Cancer. 2017 Jul 15;8(12):2154-2162. doi: 10.7150/jca.19254. eCollection 2017.


Correction: Whole-Genome Saliva and Blood DNA Methylation Profiling in Individuals with a Respiratory Allergy.

Langie SAS, Szarc Vel Szic K, Declerck K, Traen S, Koppen G, Van Camp G, Schoeters G, Berghe WV, De Boever P.

PLoS One. 2017 Aug 7;12(8):e0183088. doi: 10.1371/journal.pone.0183088. eCollection 2017.


Prolonged Right Ventricular Ejection Delay in Brugada Syndrome Depends on the Type of SCN5A Variant - Electromechanical Coupling Through Tissue Velocity Imaging as a Bridge Between Genotyping and Phenotyping.

Van Malderen SCH, Daneels D, Kerkhove D, Peeters U, Theuns DAMJ, Droogmans S, Van Camp G, Weytjens C, Biervliet M, Bonduelle M, Van Dooren S, Brugada P.

Circ J. 2017 Dec 25;82(1):53-61. doi: 10.1253/circj.CJ-16-1279. Epub 2017 Aug 4.


Minimally invasive mitral valve annuloplasty confers a long-term survival benefit compared with state-of-the-art treatment in heart failure with functional mitral regurgitation.

Penicka M, Kotrc M, Ondrus T, Mo Y, Casselman F, Vanderheyden M, Van Camp G, Van Praet F, Bartunek J.

Int J Cardiol. 2017 Oct 1;244:235-241. doi: 10.1016/j.ijcard.2017.06.029. Epub 2017 Jun 8.


Molecular diagnostics for hereditary hearing loss in children.

Sommen M, Wuyts W, Van Camp G.

Expert Rev Mol Diagn. 2017 Aug;17(8):751-760. doi: 10.1080/14737159.2017.1340834. Epub 2017 Jun 19. Review.


Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies.

Boeckx N, Koukakis R, Op de Beeck K, Rolfo C, Van Camp G, Siena S, Tabernero J, Douillard JY, André T, Peeters M.

Ann Oncol. 2017 Aug 1;28(8):1862-1868. doi: 10.1093/annonc/mdx119.


DFNA5 promoter methylation a marker for breast tumorigenesis.

Croes L, de Beeck KO, Pauwels P, Vanden Berghe W, Peeters M, Fransen E, Van Camp G.

Oncotarget. 2017 May 9;8(19):31948-31958. doi: 10.18632/oncotarget.16654.


Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk-an exploratory study.

Declerck K, Remy S, Wohlfahrt-Veje C, Main KM, Van Camp G, Schoeters G, Vanden Berghe W, Andersen HR.

Clin Epigenetics. 2017 Apr 5;9:35. doi: 10.1186/s13148-017-0336-4. eCollection 2017.


A Pilot Genome-Wide Association Study Identifies Potential Metabolic Pathways Involved in Tinnitus.

Gilles A, Van Camp G, Van de Heyning P, Fransen E.

Front Neurosci. 2017 Mar 2;11:71. doi: 10.3389/fnins.2017.00071. eCollection 2017.


Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.

Deben C, Van den Bossche J, Van Der Steen N, Lardon F, Wouters A, de Beeck KO, Hermans C, Jacobs J, Peeters M, Van Camp G, Rolfo C, Deschoolmeester V, Pauwels P.

Tumour Biol. 2017 Feb;39(2):1010428317694327. doi: 10.1177/1010428317694327.


Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.

Picher MM, Gehrt A, Meese S, Ivanovic A, Predoehl F, Jung S, Schrauwen I, Dragonetti AG, Colombo R, Van Camp G, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1717-E1726. doi: 10.1073/pnas.1617533114. Epub 2017 Feb 9.

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