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Items: 37


A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.

Almeida-Souza L, Frank RAW, García-Nafría J, Colussi A, Gunawardana N, Johnson CM, Yu M, Howard G, Andrews B, Vallis Y, McMahon HT.

Cell. 2018 Jul 12;174(2):325-337.e14. doi: 10.1016/j.cell.2018.05.020. Epub 2018 Jun 7.


Endophilin marks and controls a clathrin-independent endocytic pathway.

Boucrot E, Ferreira AP, Almeida-Souza L, Debard S, Vallis Y, Howard G, Bertot L, Sauvonnet N, McMahon HT.

Nature. 2015 Jan 22;517(7535):460-5. doi: 10.1038/nature14067. Epub 2014 Dec 17.


GRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctions.

Lucken-Ardjomande Häsler S, Vallis Y, Jolin HE, McKenzie AN, McMahon HT.

J Cell Sci. 2014 Nov 1;127(Pt 21):4602-19. doi: 10.1242/jcs.147694. Epub 2014 Sep 4.


Hsc70-induced changes in clathrin-auxilin cage structure suggest a role for clathrin light chains in cage disassembly.

Young A, Stoilova-McPhie S, Rothnie A, Vallis Y, Harvey-Smith P, Ranson N, Kent H, Brodsky FM, Pearse BM, Roseman A, Smith CJ.

Traffic. 2013 Sep;14(9):987-96. doi: 10.1111/tra.12085. Epub 2013 Jun 20.


Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells.

Arsenault J, Ferrari E, Niranjan D, Cuijpers SA, Gu C, Vallis Y, O'Brien J, Davletov B.

J Neurochem. 2013 Jul;126(2):223-33. doi: 10.1111/jnc.12284. Epub 2013 May 20.


Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.

Sánchez-Barrena MJ, Vallis Y, Clatworthy MR, Doherty GJ, Veprintsev DB, Evans PR, McMahon HT.

PLoS One. 2012;7(12):e52401. doi: 10.1371/journal.pone.0052401. Epub 2012 Dec 20. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/3bdc487b-5e25-4cd7-a354-b2952eec943d.


Assembly of protein building blocks using a short synthetic peptide.

Ferrari E, Soloviev M, Niranjan D, Arsenault J, Gu C, Vallis Y, O'Brien J, Davletov B.

Bioconjug Chem. 2012 Mar 21;23(3):479-84. doi: 10.1021/bc2005208. Epub 2012 Feb 10.


Endophilin drives the fast mode of vesicle retrieval in a ribbon synapse.

Llobet A, Gallop JL, Burden JJE, Çamdere G, Chandra P, Vallis Y, Hopkins CR, Lagnado L, McMahon HT.

J Neurosci. 2011 Jun 8;31(23):8512-8519. doi: 10.1523/JNEUROSCI.6223-09.2011.


FCHo proteins are nucleators of clathrin-mediated endocytosis.

Henne WM, Boucrot E, Meinecke M, Evergren E, Vallis Y, Mittal R, McMahon HT.

Science. 2010 Jun 4;328(5983):1281-4. doi: 10.1126/science.1188462. Epub 2010 May 6.


The acetyltransferase activity of the bacterial toxin YopJ of Yersinia is activated by eukaryotic host cell inositol hexakisphosphate.

Mittal R, Peak-Chew SY, Sade RS, Vallis Y, McMahon HT.

J Biol Chem. 2010 Jun 25;285(26):19927-34. doi: 10.1074/jbc.M110.126581. Epub 2010 Apr 29.


The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway.

Lundmark R, Doherty GJ, Howes MT, Cortese K, Vallis Y, Parton RG, McMahon HT.

Curr Biol. 2008 Nov 25;18(22):1802-8. doi: 10.1016/j.cub.2008.10.044.


Arf family GTP loading is activated by, and generates, positive membrane curvature.

Lundmark R, Doherty GJ, Vallis Y, Peter BJ, McMahon HT.

Biochem J. 2008 Sep 1;414(2):189-94. doi: 10.1042/BJ20081237.


Solitary and repetitive binding motifs for the AP2 complex alpha-appendage in amphiphysin and other accessory proteins.

Olesen LE, Ford MG, Schmid EM, Vallis Y, Babu MM, Li PH, Mills IG, McMahon HT, Praefcke GJ.

J Biol Chem. 2008 Feb 22;283(8):5099-109. Epub 2007 Nov 6.


Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.

Daumke O, Lundmark R, Vallis Y, Martens S, Butler PJ, McMahon HT.

Nature. 2007 Oct 18;449(7164):923-7. No abstract available.


Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

Gill DJ, Teo H, Sun J, Perisic O, Veprintsev DB, Vallis Y, Emr SD, Williams RL.

Biochem Soc Symp. 2007;(74):47-57. Review.


ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes.

Teo H, Gill DJ, Sun J, Perisic O, Veprintsev DB, Vallis Y, Emr SD, Williams RL.

Cell. 2006 Apr 7;125(1):99-111.


Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis.

Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, Babu MM, Mills IG, McMahon HT.

EMBO J. 2004 Nov 10;23(22):4371-83. Epub 2004 Oct 21.


BAR domains as sensors of membrane curvature: the amphiphysin BAR structure.

Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJ, Evans PR, McMahon HT.

Science. 2004 Jan 23;303(5657):495-9. Epub 2003 Nov 26.


Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter.

Tate CG, Haase J, Baker C, Boorsma M, Magnani F, Vallis Y, Williams DC.

Biochim Biophys Acta. 2003 Feb 17;1610(1):141-53.


EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.

Mills IG, Praefcke GJ, Vallis Y, Peter BJ, Olesen LE, Gallop JL, Butler PJ, Evans PR, McMahon HT.

J Cell Biol. 2003 Jan 20;160(2):213-22. Epub 2003 Jan 21.


Curvature of clathrin-coated pits driven by epsin.

Ford MG, Mills IG, Peter BJ, Vallis Y, Praefcke GJ, Evans PR, McMahon HT.

Nature. 2002 Sep 26;419(6905):361-6.


GTPase activity of dynamin and resulting conformation change are essential for endocytosis.

Marks B, Stowell MH, Vallis Y, Mills IG, Gibson A, Hopkins CR, McMahon HT.

Nature. 2001 Mar 8;410(6825):231-5.


Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes.

Ford MG, Pearse BM, Higgins MK, Vallis Y, Owen DJ, Gibson A, Hopkins CR, Evans PR, McMahon HT.

Science. 2001 Feb 9;291(5506):1051-5.


Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4.

Haley JE, Abogadie FC, Fernandez-Fernandez JM, Dayrell M, Vallis Y, Buckley NJ, Brown DA.

J Neurosci. 2000 Nov 1;20(21):RC105.


The structure and function of the beta 2-adaptin appendage domain.

Owen DJ, Vallis Y, Pearse BM, McMahon HT, Evans PR.

EMBO J. 2000 Aug 15;19(16):4216-27.


A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.

Owen DJ, Vallis Y, Noble ME, Hunter JB, Dafforn TR, Evans PR, McMahon HT.

Cell. 1999 Jun 11;97(6):805-15.


Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis.

Vallis Y, Wigge P, Marks B, Evans PR, McMahon HT.

Curr Biol. 1999 Mar 11;9(5):257-60.


Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.

Owen DJ, Wigge P, Vallis Y, Moore JD, Evans PR, McMahon HT.

EMBO J. 1998 Sep 15;17(18):5273-85.


The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons.

Haley JE, Abogadie FC, Delmas P, Dayrell M, Vallis Y, Milligan G, Caulfield MP, Brown DA, Buckley NJ.

J Neurosci. 1998 Jun 15;18(12):4521-31.


Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis.

Wigge P, Köhler K, Vallis Y, Doyle CA, Owen D, Hunt SP, McMahon HT.

Mol Biol Cell. 1997 Oct;8(10):2003-15.


Assembly of GABAA receptors composed of alpha1 and beta2 subunits in both cultured neurons and fibroblasts.

Gorrie GH, Vallis Y, Stephenson A, Whitfield J, Browning B, Smart TG, Moss SJ.

J Neurosci. 1997 Sep 1;17(17):6587-96.


Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain.

Wigge P, Vallis Y, McMahon HT.

Curr Biol. 1997 Aug 1;7(8):554-60.


Use of antisense-generating plasmids to probe the function of signal transduction proteins in primary neurons.

Abogadie FC, Vallis Y, Buckley NJ, Caulfield MP.

Methods Mol Biol. 1997;83:217-25. Review. No abstract available.


Muscarinic M-current inhibition via G alpha q/11 and alpha-adrenoceptor inhibition of Ca2+ current via G alpha o in rat sympathetic neurones.

Caulfield MP, Jones S, Vallis Y, Buckley NJ, Kim GD, Milligan G, Brown DA.

J Physiol. 1994 Jun 15;477 ( Pt 3):415-22.


Injection of antisera into cells to study G-protein regulation of channel function.

McFadzean I, Caulfield MP, Vallis Y, Brown DA.

Methods Enzymol. 1994;238:357-64. No abstract available.


Bradykinin enhances excitability in cultured rat sensory neurones by a GTP-dependent mechanism.

McGuirk SM, Vallis Y, Pasternak CA, Dolphin AC.

Neurosci Lett. 1989 Apr 24;99(1-2):85-9.


Characteristics of lymphocyte chromatin from Alzheimer's disease patients and from young and old normal individuals.

Smith TA, Vallis Y, Neary D, Itzhaki RF.

Gerontology. 1989;35(5-6):268-74.


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