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Items: 22

1.

Control of Antibody Impurities Induced by Riboflavin in Culture Media During Production.

Wallace A, Trimble S, Valliere-Douglass JF, Allen M, Eakin C, Balland A, Reddy P, Treuheit MJ.

J Pharm Sci. 2019 Oct 26. pii: S0022-3549(19)30676-8. doi: 10.1016/j.xphs.2019.10.039. [Epub ahead of print]

PMID:
31669653
2.

Biopharmaceutical Industry Practices for Sequence Variant Analyses of Recombinant Protein Therapeutics.

Valliere-Douglass J, Marzilli L, Deora A, Du Z, He L, Kumar S, Liu YH, Martin-Mueller H, Nwosu C, Stults J, Wang Y, Yaghmour S, Zhou Y.

PDA J Pharm Sci Technol. 2019 Jun 17. pii: pdajpst.2019.010009. doi: 10.5731/pdajpst.2019.010009. [Epub ahead of print]

PMID:
31209169
3.

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.

Li F, Sutherland MK, Yu C, Walter RB, Westendorf L, Valliere-Douglass J, Pan L, Cronkite A, Sussman D, Klussman K, Ulrich M, Anderson ME, Stone IJ, Zeng W, Jonas M, Lewis TS, Goswami M, Wang SA, Senter PD, Law CL, Feldman EJ, Benjamin DR.

Mol Cancer Ther. 2018 Feb;17(2):554-564. doi: 10.1158/1535-7163.MCT-17-0742. Epub 2017 Nov 15.

4.

ELISA reagent coverage evaluation by affinity purification tandem mass spectrometry.

Henry SM, Sutlief E, Salas-Solano O, Valliere-Douglass J.

MAbs. 2017 Oct;9(7):1065-1075. doi: 10.1080/19420862.2017.1349586. Epub 2017 Jul 14.

5.

Localized conformational interrogation of antibody and antibody-drug conjugates by site-specific carboxyl group footprinting.

Pan LY, Salas-Solano O, Valliere-Douglass JF.

MAbs. 2017 Feb/Mar;9(2):307-318. doi: 10.1080/19420862.2016.1268306. Epub 2016 Dec 8.

6.

Characterization of acidic and basic variants of IgG1 therapeutic monoclonal antibodies based on non-denaturing IEF fractionation.

Dada OO, Jaya N, Valliere-Douglass J, Salas-Solano O.

Electrophoresis. 2015 Nov;36(21-22):2695-2702. doi: 10.1002/elps.201500219. Epub 2015 Sep 18.

PMID:
26289680
7.

Antibody structural integrity of site-specific antibody-drug conjugates investigated by hydrogen/deuterium exchange mass spectrometry.

Pan LY, Salas-Solano O, Valliere-Douglass JF.

Anal Chem. 2015 Jun 2;87(11):5669-76. doi: 10.1021/acs.analchem.5b00764. Epub 2015 May 15.

PMID:
25938577
8.

Approaches to Interchain Cysteine-Linked ADC Characterization by Mass Spectrometry.

Valliere-Douglass JF, Hengel SM, Pan LY.

Mol Pharm. 2015 Jun 1;12(6):1774-83. doi: 10.1021/mp500614p. Epub 2014 Dec 17. Review.

PMID:
25474122
9.

Solid-state mAbs and ADCs subjected to heat-stress stability conditions can be covalently modified with buffer and excipient molecules.

Valliere-Douglass JF, Lewis P, Salas-Solano O, Jiang S.

J Pharm Sci. 2015 Feb;104(2):652-65. doi: 10.1002/jps.24276. Epub 2014 Dec 2.

PMID:
25470745
10.

Measurement of in vivo drug load distribution of cysteine-linked antibody-drug conjugates using microscale liquid chromatography mass spectrometry.

Hengel SM, Sanderson R, Valliere-Douglass J, Nicholas N, Leiske C, Alley SC.

Anal Chem. 2014 Apr 1;86(7):3420-5. doi: 10.1021/ac403860c. Epub 2014 Mar 14.

PMID:
24576206
11.

Conformation and dynamics of interchain cysteine-linked antibody-drug conjugates as revealed by hydrogen/deuterium exchange mass spectrometry.

Pan LY, Salas-Solano O, Valliere-Douglass JF.

Anal Chem. 2014 Mar 4;86(5):2657-64. doi: 10.1021/ac404003q. Epub 2014 Feb 21.

PMID:
24512515
12.

Native intact mass determination of antibodies conjugated with monomethyl Auristatin E and F at interchain cysteine residues.

Valliere-Douglass JF, McFee WA, Salas-Solano O.

Anal Chem. 2012 Mar 20;84(6):2843-9. doi: 10.1021/ac203346c. Epub 2012 Mar 2.

PMID:
22384990
13.

Photochemical degradation of citrate buffers leads to covalent acetonation of recombinant protein therapeutics.

Valliere-Douglass JF, Connell-Crowley L, Jensen R, Schnier PD, Trilisky E, Leith M, Follstad BD, Kerr J, Lewis N, Vunnum S, Treuheit MJ, Balland A, Wallace A.

Protein Sci. 2010 Nov;19(11):2152-63. doi: 10.1002/pro.495.

14.

Resolving disulfide structural isoforms of IgG2 monoclonal antibodies by ion mobility mass spectrometry.

Bagal D, Valliere-Douglass JF, Balland A, Schnier PD.

Anal Chem. 2010 Aug 15;82(16):6751-5. doi: 10.1021/ac1013139.

PMID:
20704363
15.

Glutamine-linked and non-consensus asparagine-linked oligosaccharides present in human recombinant antibodies define novel protein glycosylation motifs.

Valliere-Douglass JF, Eakin CM, Wallace A, Ketchem RR, Wang W, Treuheit MJ, Balland A.

J Biol Chem. 2010 May 21;285(21):16012-22. doi: 10.1074/jbc.M109.096412. Epub 2010 Mar 16.

16.

Asparagine-linked oligosaccharides present on a non-consensus amino acid sequence in the CH1 domain of human antibodies.

Valliere-Douglass JF, Kodama P, Mujacic M, Brady LJ, Wang W, Wallace A, Yan B, Reddy P, Treuheit MJ, Balland A.

J Biol Chem. 2009 Nov 20;284(47):32493-506. doi: 10.1074/jbc.M109.014803. Epub 2009 Sep 18.

17.

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.

Yan B, Steen S, Hambly D, Valliere-Douglass J, Vanden Bos T, Smallwood S, Yates Z, Arroll T, Han Y, Gadgil H, Latypov RF, Wallace A, Lim A, Kleemann GR, Wang W, Balland A.

J Pharm Sci. 2009 Oct;98(10):3509-21. doi: 10.1002/jps.21655.

PMID:
19475547
18.

Separation of populations of antibody variants by fine tuning of hydrophobic-interaction chromatography operating conditions.

Valliere-Douglass J, Wallace A, Balland A.

J Chromatogr A. 2008 Dec 19;1214(1-2):81-9. doi: 10.1016/j.chroma.2008.10.078. Epub 2008 Oct 25.

PMID:
19012891
19.

O-fucosylation of an antibody light chain: characterization of a modification occurring on an IgG1 molecule.

Valliere-Douglass JF, Brady LJ, Farnsworth C, Pace D, Balland A, Wallace A, Wang W, Treuheit MJ, Yan B.

Glycobiology. 2009 Feb;19(2):144-52. doi: 10.1093/glycob/cwn116. Epub 2008 Oct 24.

PMID:
18952827
20.

Separation and characterization of an IgG2 antibody containing a cyclic imide in CDR1 of light chain by hydrophobic interaction chromatography and mass spectrometry.

Valliere-Douglass J, Jones L, Shpektor D, Kodama P, Wallace A, Balland A, Bailey R, Zhang Y.

Anal Chem. 2008 May 1;80(9):3168-74. doi: 10.1021/ac702245c. Epub 2008 Mar 21.

PMID:
18355059
21.

Molecular mass analysis of antibodies by on-line SEC-MS.

Brady LJ, Valliere-Douglass J, Martinez T, Balland A.

J Am Soc Mass Spectrom. 2008 Apr;19(4):502-9. doi: 10.1016/j.jasms.2007.12.006. Epub 2008 Jan 4.

22.

Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.

Yan B, Valliere-Douglass J, Brady L, Steen S, Han M, Pace D, Elliott S, Yates Z, Han Y, Balland A, Wang W, Pettit D.

J Chromatogr A. 2007 Sep 14;1164(1-2):153-61. Epub 2007 Jul 5.

PMID:
17640657

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