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Items: 1 to 50 of 125

1.

Cell-free circulating epimarks in cancer monitoring.

Duforestel M, Briand J, Bougras-Cartron G, Heymann D, Frenel JS, Vallette FM, Cartron PF.

Epigenomics. 2020 Jan;12(2):145-155. doi: 10.2217/epi-2019-0170. Epub 2020 Jan 9.

PMID:
31916450
2.

Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma.

Rabé M, Dumont S, Álvarez-Arenas A, Janati H, Belmonte-Beitia J, Calvo GF, Thibault-Carpentier C, Séry Q, Chauvin C, Joalland N, Briand F, Blandin S, Scotet E, Pecqueur C, Clairambault J, Oliver L, Perez-Garcia V, Nadaradjane A, Cartron PF, Gratas C, Vallette FM.

Cell Death Dis. 2020 Jan 6;11(1):19. doi: 10.1038/s41419-019-2200-2.

3.

Diuron exposure and Akt overexpression promote glioma formation through DNA hypomethylation.

Briand J, Nadaradjane A, Bougras-Cartron G, Olivier C, Vallette FM, Cartron PF.

Clin Epigenetics. 2019 Nov 14;11(1):159. doi: 10.1186/s13148-019-0759-1.

4.

Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis.

Valès S, Bacola G, Biraud M, Touvron M, Bessard A, Geraldo F, Dougherty KA, Lashani S, Bossard C, Flamant M, Duchalais E, Marionneau-Lambot S, Oullier T, Oliver L, Neunlist M, Vallette FM, Van Landeghem L.

EBioMedicine. 2019 Nov;49:172-188. doi: 10.1016/j.ebiom.2019.09.045. Epub 2019 Oct 26.

5.

Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner.

Duforestel M, Nadaradjane A, Bougras-Cartron G, Briand J, Olivier C, Frenel JS, Vallette FM, Lelièvre SA, Cartron PF.

Front Genet. 2019 Sep 27;10:885. doi: 10.3389/fgene.2019.00885. eCollection 2019.

6.

NKG2D Controls Natural Reactivity of Vγ9Vδ2 T Lymphocytes against Mesenchymal Glioblastoma Cells.

Chauvin C, Joalland N, Perroteau J, Jarry U, Lafrance L, Willem C, Retière C, Oliver L, Gratas C, Gautreau-Rolland L, Saulquin X, Vallette FM, Vié H, Scotet E, Pecqueur C.

Clin Cancer Res. 2019 Dec 1;25(23):7218-7228. doi: 10.1158/1078-0432.CCR-19-0375. Epub 2019 Sep 10.

PMID:
31506386
7.

Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.

Leveque X, Hochane M, Geraldo F, Dumont S, Gratas C, Oliver L, Gaignier C, Trichet V, Layrolle P, Heymann D, Herault O, Vallette FM, Olivier C.

Stem Cells. 2019 Aug;37(8):1083-1094. doi: 10.1002/stem.3014. Epub 2019 Apr 17.

8.

miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker.

Nadaradjane A, Briand J, Bougras-Cartron G, Disdero V, Vallette FM, Frenel JS, Cartron PF.

Mol Ther Nucleic Acids. 2018 Dec 7;13:642-650. doi: 10.1016/j.omtn.2018.09.007. Epub 2018 Sep 13.

9.

Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: myth or reality?

Brown HK, Tellez-Gabriel M, Cartron PF, Vallette FM, Heymann MF, Heymann D.

Drug Discov Today. 2019 Mar;24(3):763-772. doi: 10.1016/j.drudis.2018.11.017. Epub 2018 Nov 26. Review.

10.

Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer.

Vallette FM, Olivier C, Lézot F, Oliver L, Cochonneau D, Lalier L, Cartron PF, Heymann D.

Biochem Pharmacol. 2019 Apr;162:169-176. doi: 10.1016/j.bcp.2018.11.004. Epub 2018 Nov 9. Review.

11.

IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors.

Joalland N, Chauvin C, Oliver L, Vallette FM, Pecqueur C, Jarry U, Scotet E.

J Immunother. 2018 Jun;41(5):224-231. doi: 10.1097/CJI.0000000000000225.

PMID:
29683891
12.

Pharmacological targeting of apelin impairs glioblastoma growth.

Harford-Wright E, Andre-Gregoire G, Jacobs KA, Treps L, Le Gonidec S, Leclair HM, Gonzalez-Diest S, Roux Q, Guillonneau F, Loussouarn D, Oliver L, Vallette FM, Foufelle F, Valet P, Davenport AP, Glen RC, Bidere N, Gavard J.

Brain. 2017 Nov 1;140(11):2939-2954. doi: 10.1093/brain/awx253.

13.

HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide.

Séry Q, Rabé M, Oliver L, Vallette FM, Gratas C.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1377-1383. doi: 10.1016/j.bbrc.2017.09.162. Epub 2017 Sep 29.

PMID:
28970067
14.

Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.

Oizel K, Chauvin C, Oliver L, Gratas C, Geraldo F, Jarry U, Scotet E, Rabe M, Alves-Guerra MC, Teusan R, Gautier F, Loussouarn D, Compan V, Martinou JC, Vallette FM, Pecqueur C.

Clin Cancer Res. 2017 Oct 15;23(20):6292-6304. doi: 10.1158/1078-0432.CCR-16-3102. Epub 2017 Jul 18.

15.

Sensitization of EGFR Wild-Type Non-Small Cell Lung Cancer Cells to EGFR-Tyrosine Kinase Inhibitor Erlotinib.

Raimbourg J, Joalland MP, Cabart M, de Plater L, Bouquet F, Savina A, Decaudin D, Bennouna J, Vallette FM, Lalier L.

Mol Cancer Ther. 2017 Aug;16(8):1634-1644. doi: 10.1158/1535-7163.MCT-17-0075. Epub 2017 May 18.

16.

Low-Dose Pesticide Mixture Induces Senescence in Normal Mesenchymal Stem Cells (MSC) and Promotes Tumorigenic Phenotype in Premalignant MSC.

Hochane M, Trichet V, Pecqueur C, Avril P, Oliver L, Denis J, Brion R, Amiaud J, Pineau A, Naveilhan P, Heymann D, Vallette FM, Olivier C.

Stem Cells. 2017 Mar;35(3):800-811. doi: 10.1002/stem.2539. Epub 2016 Nov 23.

17.

The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death.

Petit E, Cartron PF, Oliver L, Vallette FM.

Cell Signal. 2017 Jan;30:171-178. doi: 10.1016/j.cellsig.2016.11.008. Epub 2016 Nov 12.

18.

Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth.

Cheray M, Pacaud R, Nadaradjane A, Oliver L, Vallette FM, Cartron PF.

Theranostics. 2016 Aug 25;6(11):1988-1999. eCollection 2016.

19.

Stereotaxic administrations of allogeneic human Vγ9Vδ2 T cells efficiently control the development of human glioblastoma brain tumors.

Jarry U, Chauvin C, Joalland N, Léger A, Minault S, Robard M, Bonneville M, Oliver L, Vallette FM, Vié H, Pecqueur C, Scotet E.

Oncoimmunology. 2016 Mar 30;5(6):e1168554. doi: 10.1080/2162402X.2016.1168554. eCollection 2016 Jun.

20.

D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH.

Oizel K, Gratas C, Nadaradjane A, Oliver L, Vallette FM, Pecqueur C.

Cell Death Dis. 2015 Mar 26;6:e1704. doi: 10.1038/cddis.2015.13.

21.

Radiation-induced PGE2 sustains human glioma cells growth and survival through EGF signaling.

Brocard E, Oizel K, Lalier L, Pecqueur C, Paris F, Vallette FM, Oliver L.

Oncotarget. 2015 Mar 30;6(9):6840-9.

22.

Histone H3 phosphorylation in GBM: a new rational to guide the use of kinase inhibitors in anti-GBM therapy.

Pacaud R, Cheray M, Nadaradjane A, Vallette FM, Cartron PF.

Theranostics. 2015 Jan 1;5(1):12-22. doi: 10.7150/thno.8799. eCollection 2015.

23.

Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness.

Cheray M, Nadaradjane A, Bonnet P, Routier S, Vallette FM, Cartron PF.

Epigenomics. 2014 Jun;6(3):267-75. doi: 10.2217/epi.14.18.

PMID:
25111481
24.

DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1.

Pacaud R, Sery Q, Oliver L, Vallette FM, Tost J, Cartron PF.

Biochimie. 2014 Sep;104:36-49. doi: 10.1016/j.biochi.2014.05.005. Epub 2014 Jun 18.

PMID:
24952347
25.

Bioactive lipids and the control of Bax pro-apoptotic activity.

Mignard V, Lalier L, Paris F, Vallette FM.

Cell Death Dis. 2014 May 29;5:e1266. doi: 10.1038/cddis.2014.226. Review.

26.

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma.

Gratas C, Séry Q, Rabé M, Oliver L, Vallette FM.

Oncotarget. 2014 May 15;5(9):2428-35.

27.

Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis.

Cartron PF, Petit E, Bellot G, Oliver L, Vallette FM.

Cell Signal. 2014 Sep;26(9):1928-34. doi: 10.1016/j.cellsig.2014.04.021. Epub 2014 May 2.

PMID:
24794530
28.

Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells.

Galan-Moya EM, Treps L, Oliver L, Chneiweiss H, Vallette FM, Bidère N, Gavard J.

PLoS One. 2014 Mar 28;9(3):e93505. doi: 10.1371/journal.pone.0093505. eCollection 2014.

29.

The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures.

Pacaud R, Brocard E, Lalier L, Hervouet E, Vallette FM, Cartron PF.

Sci Rep. 2014 Mar 18;4:4230. doi: 10.1038/srep04230.

30.

Control of glioma cell death and differentiation by PKM2-Oct4 interaction.

Morfouace M, Lalier L, Oliver L, Cheray M, Pecqueur C, Cartron PF, Vallette FM.

Cell Death Dis. 2014 Jan 30;5:e1036. doi: 10.1038/cddis.2013.561.

31.

Identification of TET1 Partners That Control Its DNA-Demethylating Function.

Cartron PF, Nadaradjane A, Lepape F, Lalier L, Gardie B, Vallette FM.

Genes Cancer. 2013 May;4(5-6):235-41. doi: 10.1177/1947601913489020.

32.

Antioxidants delay clinical signs and systemic effects of ENU induced brain tumors in rats.

Hervouet E, Staehlin O, Pouliquen D, Debien E, Cartron PF, Menanteau J, Vallette FM, Olivier C.

Nutr Cancer. 2013;65(5):686-94. doi: 10.1080/01635581.2013.789541.

PMID:
23859036
33.

Specific inhibition of one DNMT1-including complex influences tumor initiation and progression.

Cheray M, Pacaud R, Nadaradjane A, Vallette FM, Cartron PF.

Clin Epigenetics. 2013 Jun 28;5(1):9. doi: 10.1186/1868-7083-5-9.

34.

Targeting metabolism to induce cell death in cancer cells and cancer stem cells.

Pecqueur C, Oliver L, Oizel K, Lalier L, Vallette FM.

Int J Cell Biol. 2013;2013:805975. doi: 10.1155/2013/805975. Epub 2013 Feb 12.

35.

Differentiation-related response to DNA breaks in human mesenchymal stem cells.

Oliver L, Hue E, Séry Q, Lafargue A, Pecqueur C, Paris F, Vallette FM.

Stem Cells. 2013 Apr;31(4):800-7. doi: 10.1002/stem.1336.

36.

HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression.

Cartron PF, Blanquart C, Hervouet E, Gregoire M, Vallette FM.

Mol Oncol. 2013 Jun;7(3):452-63. doi: 10.1016/j.molonc.2012.11.004. Epub 2012 Dec 21.

37.

DNA methylation and apoptosis resistance in cancer cells.

Hervouet E, Cheray M, Vallette FM, Cartron PF.

Cells. 2013 Jul 18;2(3):545-73. doi: 10.3390/cells2030545.

38.

Prognostic impact of the expression/phosphorylation of the BH3-only proteins of the BCL-2 family in glioblastoma multiforme.

Cartron PF, Loussouarn D, Campone M, Martin SA, Vallette FM.

Cell Death Dis. 2012 Nov 15;3:e421. doi: 10.1038/cddis.2012.150.

39.

Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and promising therapeutic applications.

Morfouace M, Lalier L, Bahut M, Bonnamain V, Naveilhan P, Guette C, Oliver L, Gueguen N, Reynier P, Vallette FM.

J Biol Chem. 2012 Sep 28;287(40):33664-74. Epub 2012 Jul 10.

40.

Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells.

Oliver L, Hue E, Priault M, Vallette FM.

Stem Cells Dev. 2012 Oct 10;21(15):2779-88. doi: 10.1089/scd.2012.0124. Epub 2012 Jun 13.

PMID:
22519885
41.

Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle.

Hervouet E, Nadaradjane A, Gueguen M, Vallette FM, Cartron PF.

Cell Div. 2012 Feb 20;7:5. doi: 10.1186/1747-1028-7-5.

42.

Folate supplementation limits the tumourigenesis in rodent models of gliomagenesis.

Cartron PF, Hervouet E, Debien E, Olivier C, Pouliquen D, Menanteau J, Loussouarn D, Martin SA, Campone M, Vallette FM.

Eur J Cancer. 2012 Oct;48(15):2431-41. doi: 10.1016/j.ejca.2012.01.002. Epub 2012 Feb 8.

PMID:
22325970
43.

ABT-737 and/or folate reverse the PDGF-induced alterations in the mitochondrial apoptotic pathway in low-grade glioma patients.

Debien E, Hervouet E, Gautier F, Juin P, Vallette FM, Cartron PF.

Clin Epigenetics. 2011 Aug;2(2):369-381. Epub 2011 May 15.

44.

Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation.

Oliver L, Hue E, Rossignol J, Bougras G, Hulin P, Naveilhan P, Heymann D, Lescaudron L, Vallette FM.

PLoS One. 2011 May 12;6(5):e19820. doi: 10.1371/journal.pone.0019820.

45.

Increase in intracellular PGE2 induces apoptosis in Bax-expressing colon cancer cell.

Lalier L, Pedelaborde F, Braud C, Menanteau J, Vallette FM, Olivier C.

BMC Cancer. 2011 Apr 27;11:153. doi: 10.1186/1471-2407-11-153.

46.

Proximity ligation in situ assay for monitoring the global DNA methylation in cells.

Hervouet E, Hulin P, Vallette FM, Cartron PF.

BMC Biotechnol. 2011 Apr 6;11:31. doi: 10.1186/1472-6750-11-31.

47.

Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.

Gautier F, Guillemin Y, Cartron PF, Gallenne T, Cauquil N, Le Diguarher T, Casara P, Vallette FM, Manon S, Hickman JA, Geneste O, Juin P.

Mol Cell Biol. 2011 Feb;31(4):832-44. doi: 10.1128/MCB.00161-10. Epub 2010 Dec 20.

48.

Prostaglandins antagonistically control Bax activation during apoptosis.

Lalier L, Cartron PF, Olivier C, Logé C, Bougras G, Robert JM, Oliver L, Vallette FM.

Cell Death Differ. 2011 Mar;18(3):528-37. doi: 10.1038/cdd.2010.128. Epub 2010 Oct 22.

49.

Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells.

Hervouet E, Lalier L, Debien E, Cheray M, Geairon A, Rogniaux H, Loussouarn D, Martin SA, Vallette FM, Cartron PF.

PLoS One. 2010 Jun 29;5(6):e11333. doi: 10.1371/journal.pone.0011333.

50.

Dnmt1/Transcription factor interactions: an alternative mechanism of DNA methylation inheritance.

Hervouet E, Vallette FM, Cartron PF.

Genes Cancer. 2010 May;1(5):434-43. doi: 10.1177/1947601910373794.

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