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Items: 20

1.

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.

Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB, Chang D, Bailey P, Scarpa A, Lawlor R, Chelala C, Keyse SM, Biankin A, Morton JP, Evans TJ, Barry ST, Sansom OJ, Kocher HM, Marshall JF.

J Pathol. 2019 Jul 1. doi: 10.1002/path.5320. [Epub ahead of print]

PMID:
31259422
2.

Reliving, Replaying Lived Experiences Through Auditory Verbal Hallucinations: Implications on Theories and Management.

Vallath S, Luhrmann T, Bunders J, Ravikant L, Gopikumar V.

Front Psychiatry. 2018 Oct 30;9:528. doi: 10.3389/fpsyt.2018.00528. eCollection 2018.

3.

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.

Kolluri KK, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, Williams S, Barthorpe S, Lightfoot H, Busacca S, Sharkey A, Yuan Z, Sage EK, Vallath S, Le Quesne J, Tice DA, Alrifai D, von Karstedt S, Montinaro A, Guppy N, Waller DA, Nakas A, Good R, Holmes A, Walczak H, Fennell DA, Garnett M, Iorio F, Wessels L, McDermott U, Janes SM.

Elife. 2018 Jan 18;7. pii: e30224. doi: 10.7554/eLife.30224.

4.

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.

Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A, Costa-Guerra JA, Violette S, Itamochi H, Ghaem-Maghami S, Vallath S, Marshall JF, Maher J.

Mol Ther. 2017 Oct 4;25(10):2427. doi: 10.1016/j.ymthe.2017.09.018. Epub 2017 Sep 23. No abstract available.

5.

Determining the gaps between Cochrane reviews and trials of effectiveness of interventions for acute respiratory infections: an audit.

Alloo J, Vallath S, Del Mar C, Carter M, Thorning S, Clark J.

Syst Rev. 2017 Apr 13;6(1):82. doi: 10.1186/s13643-017-0472-0.

6.

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.

Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A, Costa-Guerra JA, Violette S, Itamochi H, Ghaem-Maghami S, Vallath S, Marshall JF, Maher J.

Mol Ther. 2017 Jan 4;25(1):259-273. doi: 10.1016/j.ymthe.2016.10.012. Epub 2017 Jan 4. Erratum in: Mol Ther. 2017 Oct 4;25(10):2427.

7.

The integrin αvβ6: a novel target for CAR T-cell immunotherapy?

Whilding LM, Vallath S, Maher J.

Biochem Soc Trans. 2016 Apr 15;44(2):349-55. doi: 10.1042/BST20150249. Review.

PMID:
27068939
8.

CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.

Vallath S, Sage EK, Kolluri KK, Lourenco SN, Teixeira VS, Chimalapati S, George PJ, Janes SM, Giangreco A.

Sci Rep. 2016 Apr 1;6:24006. doi: 10.1038/srep24006.

9.

Ring-shaped variation of the coeliac trunk branches.

Raikos A, Pynadath N, Anguswamy N, Vallath S, Kordali P, Stirling A.

Folia Morphol (Warsz). 2015;74(4):540-3. doi: 10.5603/FM.2015.0120.

PMID:
26620519
10.

Disruptions to processing of self referential emotional material are associated with positive symptoms of schizotypy.

Saunders J, Vallath S, Reed P.

Psychiatry Res. 2015 Oct 30;229(3):809-13. doi: 10.1016/j.psychres.2015.07.086. Epub 2015 Jul 31.

11.

Therapeutic targeting of integrin αvβ6 in breast cancer.

Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR, Haider S, Brouilette K, Saha A, Vallath S, Bowen R, Chelala C, Eccles D, Tapper WJ, Thompson AM, Quinlan P, Jordan L, Gillett C, Brentnall A, Violette S, Weinreb PH, Kendrew J, Barry ST, Hart IR, Jones JL, Marshall JF.

J Natl Cancer Inst. 2014 Jun 28;106(8). pii: dju169. doi: 10.1093/jnci/dju169. Print 2014 Aug.

12.

Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities.

Vallath S, Hynds RE, Succony L, Janes SM, Giangreco A.

Eur Respir J. 2014 Aug;44(2):513-22. doi: 10.1183/09031936.00146413. Epub 2014 Jan 16. Review.

13.

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.

Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL.

Clin Cancer Res. 2014 Jan 15;20(2):344-57. doi: 10.1158/1078-0432.CCR-13-1504. Epub 2013 Oct 22.

14.

Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5.

Coughlan L, Vallath S, Gros A, Giménez-Alejandre M, Van Rooijen N, Thomas GJ, Baker AH, Cascalló M, Alemany R, Hart IR.

Hum Gene Ther. 2012 Sep;23(9):960-79. doi: 10.1089/hum.2011.218. Epub 2012 Aug 27.

PMID:
22708837
15.

Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion.

Allen MD, Vaziri R, Green M, Chelala C, Brentnall AR, Dreger S, Vallath S, Nitch-Smith H, Hayward J, Carpenter R, Holliday DL, Walker RA, Hart IR, Jones JL.

J Pathol. 2011 Apr;223(5):646-58. doi: 10.1002/path.2833. Epub 2011 Feb 21.

PMID:
21341269
16.

Stromal features are predictive of disease mortality in oral cancer patients.

Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N, Violette SM, Weinreb PH, Chester KA, Chana JS, Marshall JF, Hart IR, Hackshaw AK, Piper K, Thomas GJ.

J Pathol. 2011 Mar;223(4):470-81. doi: 10.1002/path.2830. Epub 2011 Jan 5.

PMID:
21294121
17.

Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

Wagstaff JL, Vallath S, Marshall JF, Williamson RA, Howard MJ.

Chem Commun (Camb). 2010 Oct 28;46(40):7533-5. doi: 10.1039/c0cc01846e. Epub 2010 Sep 13.

PMID:
20838674
18.

High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.

Saha A, Ellison D, Thomas GJ, Vallath S, Mather SJ, Hart IR, Marshall JF.

J Pathol. 2010 Sep;222(1):52-63. doi: 10.1002/path.2745.

PMID:
20629113
19.

Biological and clinical implications of nicastrin expression in invasive breast cancer.

Filipović A, Gronau JH, Green AR, Wang J, Vallath S, Shao D, Rasul S, Ellis IO, Yagüe E, Sturge J, Coombes RC.

Breast Cancer Res Treat. 2011 Jan;125(1):43-53. doi: 10.1007/s10549-010-0823-1. Epub 2010 Mar 12.

PMID:
20224929
20.

In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR, Thomas GJ.

J Virol. 2009 Jul;83(13):6416-28. doi: 10.1128/JVI.00445-09. Epub 2009 Apr 15.

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