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Items: 34

1.

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition.

Furukawa T, Scheven MT, Misslinger M, Zhao C, Hoefgen S, Gsaller F, Lau J, Jöchl C, Donaldson I, Valiante V, Brakhage AA, Bromley MJ, Haas H, Hortschansky P.

Nucleic Acids Res. 2020 Feb 22. pii: gkaa109. doi: 10.1093/nar/gkaa109. [Epub ahead of print]

PMID:
32086516
2.

Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin.

Stroe MC, Netzker T, Scherlach K, Krüger T, Hertweck C, Valiante V, Brakhage AA.

Elife. 2020 Feb 21;9. pii: e52541. doi: 10.7554/eLife.52541.

3.

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus.

Manfiolli AO, Siqueira FS, Dos Reis TF, Van Dijck P, Schrevens S, Hoefgen S, Föge M, Straßburger M, de Assis LJ, Heinekamp T, Rocha MC, Janevska S, Brakhage AA, Malavazi I, Goldman GH, Valiante V.

mBio. 2019 Mar 26;10(2). pii: e00215-19. doi: 10.1128/mBio.00215-19.

4.

Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin.

Conrad T, Kniemeyer O, Henkel SG, Krüger T, Mattern DJ, Valiante V, Guthke R, Jacobsen ID, Brakhage AA, Vlaic S, Linde J.

BMC Syst Biol. 2018 Oct 20;12(1):88. doi: 10.1186/s12918-018-0620-8.

5.

Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites.

Fischer J, Müller SY, Netzker T, Jäger N, Gacek-Matthews A, Scherlach K, Stroe MC, García-Altares M, Pezzini F, Schoeler H, Reichelt M, Gershenzon J, Krespach MK, Shelest E, Schroeckh V, Valiante V, Heinzel T, Hertweck C, Strauss J, Brakhage AA.

Elife. 2018 Oct 12;7. pii: e40969. doi: 10.7554/eLife.40969.

6.

Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi.

Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V.

Metab Eng. 2018 Jul;48:44-51. doi: 10.1016/j.ymben.2018.05.014. Epub 2018 May 26.

7.

The Cell Wall Integrity Signaling Pathway and Its Involvement in Secondary Metabolite Production.

Valiante V.

J Fungi (Basel). 2017 Dec 6;3(4). pii: E68. doi: 10.3390/jof3040068. Review.

8.

Rewiring of the Austinoid Biosynthetic Pathway in Filamentous Fungi.

Mattern DJ, Valiante V, Horn F, Petzke L, Brakhage AA.

ACS Chem Biol. 2017 Dec 15;12(12):2927-2933. doi: 10.1021/acschembio.7b00814. Epub 2017 Nov 2.

PMID:
29076725
9.

Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence.

Manfiolli AO, de Castro PA, Dos Reis TF, Dolan S, Doyle S, Jones G, Riaño Pachón DM, Ulaş M, Noble LM, Mattern DJ, Brakhage AA, Valiante V, Silva-Rocha R, Bayram O, Goldman GH.

Cell Microbiol. 2017 Dec;19(12). doi: 10.1111/cmi.12770. Epub 2017 Aug 17.

PMID:
28753224
10.

Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus.

Valiante V, Mattern DJ, Schüffler A, Horn F, Walther G, Scherlach K, Petzke L, Dickhaut J, Guthke R, Hertweck C, Nett M, Thines E, Brakhage AA.

ACS Chem Biol. 2017 May 19;12(5):1227-1234. doi: 10.1021/acschembio.7b00003. Epub 2017 Mar 15.

PMID:
28233494
11.

Correction: Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina).

Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K.

PLoS Genet. 2016 Dec 5;12(12):e1006491. doi: 10.1371/journal.pgen.1006491. eCollection 2016 Dec.

12.

Regulation and Role of Fungal Secondary Metabolites.

Macheleidt J, Mattern DJ, Fischer J, Netzker T, Weber J, Schroeckh V, Valiante V, Brakhage AA.

Annu Rev Genet. 2016 Nov 23;50:371-392. Epub 2016 Oct 5. Review.

PMID:
27732794
13.

Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome Editing.

Weber J, Valiante V, Nødvig CS, Mattern DJ, Slotkowski RA, Mortensen UH, Brakhage AA.

ACS Synth Biol. 2017 Jan 20;6(1):62-68. doi: 10.1021/acssynbio.6b00203. Epub 2016 Sep 13.

PMID:
27611015
14.

The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors.

Valiante V, Baldin C, Hortschansky P, Jain R, Thywißen A, Straßburger M, Shelest E, Heinekamp T, Brakhage AA.

Mol Microbiol. 2016 Oct;102(2):321-335. doi: 10.1111/mmi.13462. Epub 2016 Jul 28.

15.

Draft Genome Sequences of Fungus Aspergillus calidoustus.

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Scherlach K, Martin K, Brakhage AA, Petzke L, Valiante V.

Genome Announc. 2016 Mar 10;4(2). pii: e00102-16. doi: 10.1128/genomeA.00102-16.

16.

Mitogen activated protein kinases SakA(HOG1) and MpkC collaborate for Aspergillus fumigatus virulence.

Bruder Nascimento AC, Dos Reis TF, de Castro PA, Hori JI, Bom VL, de Assis LJ, Ramalho LN, Rocha MC, Malavazi I, Brown NA, Valiante V, Brakhage AA, Hagiwara D, Goldman GH.

Mol Microbiol. 2016 Jun;100(5):841-59. doi: 10.1111/mmi.13354. Epub 2016 Mar 23.

17.

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus.

Altwasser R, Baldin C, Weber J, Guthke R, Kniemeyer O, Brakhage AA, Linde J, Valiante V.

PLoS One. 2015 Sep 10;10(9):e0136932. doi: 10.1371/journal.pone.0136932. eCollection 2015.

18.

Draft Genome Sequence of the Fungus Penicillium brasilianum MG11.

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Brakhage AA, Valiante V.

Genome Announc. 2015 Sep 3;3(5). pii: e00724-15. doi: 10.1128/genomeA.00724-15.

19.

Synthetic biology of fungal natural products.

Mattern DJ, Valiante V, Unkles SE, Brakhage AA.

Front Microbiol. 2015 Jul 30;6:775. doi: 10.3389/fmicb.2015.00775. eCollection 2015. Review.

20.

Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus.

Mattern DJ, Schoeler H, Weber J, Novohradská S, Kraibooj K, Dahse HM, Hillmann F, Valiante V, Figge MT, Brakhage AA.

Appl Microbiol Biotechnol. 2015 Dec;99(23):10151-61. doi: 10.1007/s00253-015-6898-1. Epub 2015 Aug 18.

PMID:
26278536
21.

Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010).

Valiante V, Monteiro MC, Martín J, Altwasser R, El Aouad N, González I, Kniemeyer O, Mellado E, Palomo S, de Pedro N, Pérez-Victoria I, Tormo JR, Vicente F, Reyes F, Genilloud O, Brakhage AA.

Antimicrob Agents Chemother. 2015 Sep;59(9):5145-53. doi: 10.1128/AAC.00683-15. Epub 2015 Jun 8.

22.

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters.

Netzker T, Fischer J, Weber J, Mattern DJ, König CC, Valiante V, Schroeckh V, Brakhage AA.

Front Microbiol. 2015 Apr 20;6:299. doi: 10.3389/fmicb.2015.00299. eCollection 2015.

23.

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence.

Valiante V, Macheleidt J, Föge M, Brakhage AA.

Front Microbiol. 2015 Apr 16;6:325. doi: 10.3389/fmicb.2015.00325. eCollection 2015. Review.

24.

Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation.

Baldin C, Valiante V, Krüger T, Schafferer L, Haas H, Kniemeyer O, Brakhage AA.

Proteomics. 2015 Jul;15(13):2230-43. doi: 10.1002/pmic.201400584. Epub 2015 May 26.

PMID:
25728394
25.

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial mucorales (Mucoromycotina).

Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K.

PLoS Genet. 2014 Aug 14;10(8):e1004496. doi: 10.1371/journal.pgen.1004496. eCollection 2014 Aug. Erratum in: PLoS Genet. 2016 Dec 5;12 (12 ):e1006491.

26.

Synthetic biology tools for bioprospecting of natural products in eukaryotes.

Unkles SE, Valiante V, Mattern DJ, Brakhage AA.

Chem Biol. 2014 Apr 24;21(4):502-508. doi: 10.1016/j.chembiol.2014.02.010. Epub 2014 Mar 13.

27.

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.

Heinekamp T, Thywißen A, Macheleidt J, Keller S, Valiante V, Brakhage AA.

Front Microbiol. 2013 Jan 18;3:440. doi: 10.3389/fmicb.2012.00440. eCollection 2012.

28.

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression.

Müller S, Baldin C, Groth M, Guthke R, Kniemeyer O, Brakhage AA, Valiante V.

BMC Genomics. 2012 Oct 2;13:519. doi: 10.1186/1471-2164-13-519.

29.

Systems biology of fungal infection.

Horn F, Heinekamp T, Kniemeyer O, Pollmächer J, Valiante V, Brakhage AA.

Front Microbiol. 2012 Apr 2;3:108. doi: 10.3389/fmicb.2012.00108. eCollection 2012.

30.

A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin.

Monteiro MC, de la Cruz M, Cantizani J, Moreno C, Tormo JR, Mellado E, De Lucas JR, Asensio F, Valiante V, Brakhage AA, Latgé JP, Genilloud O, Vicente F.

J Biomol Screen. 2012 Apr;17(4):542-9. doi: 10.1177/1087057111433459. Epub 2012 Jan 10.

PMID:
22233645
31.

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus.

Jain R, Valiante V, Remme N, Docimo T, Heinekamp T, Hertweck C, Gershenzon J, Haas H, Brakhage AA.

Mol Microbiol. 2011 Oct;82(1):39-53. doi: 10.1111/j.1365-2958.2011.07778.x. Epub 2011 Aug 30.

32.

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus.

Valiante V, Jain R, Heinekamp T, Brakhage AA.

Fungal Genet Biol. 2009 Dec;46(12):909-18. doi: 10.1016/j.fgb.2009.08.005. Epub 2009 Aug 26.

PMID:
19715768
33.

Comparative genomics of MAP kinase and calcium-calcineurin signalling components in plant and human pathogenic fungi.

Rispail N, Soanes DM, Ant C, Czajkowski R, Grünler A, Huguet R, Perez-Nadales E, Poli A, Sartorel E, Valiante V, Yang M, Beffa R, Brakhage AA, Gow NA, Kahmann R, Lebrun MH, Lenasi H, Perez-Martin J, Talbot NJ, Wendland J, Di Pietro A.

Fungal Genet Biol. 2009 Apr;46(4):287-98. doi: 10.1016/j.fgb.2009.01.002. Epub 2009 Feb 7. Review.

34.

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response.

Valiante V, Heinekamp T, Jain R, Härtl A, Brakhage AA.

Fungal Genet Biol. 2008 May;45(5):618-27. Epub 2007 Sep 25.

PMID:
17981060

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