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Items: 42

1.

Flow-enhanced vascularization and maturation of kidney organoids in vitro.

Homan KA, Gupta N, Kroll KT, Kolesky DB, Skylar-Scott M, Miyoshi T, Mau D, Valerius MT, Ferrante T, Bonventre JV, Lewis JA, Morizane R.

Nat Methods. 2019 Mar;16(3):255-262. doi: 10.1038/s41592-019-0325-y. Epub 2019 Feb 11.

2.

CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells.

Gupta N, Susa K, Yoda Y, Bonventre JV, Valerius MT, Morizane R.

Curr Protoc Stem Cell Biol. 2018 May;45(1):e50. doi: 10.1002/cpsc.50. Epub 2018 Apr 26.

3.

Disparate levels of beta-catenin activity determine nephron progenitor cell fate.

Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ.

Dev Biol. 2018 Aug 1;440(1):13-21. doi: 10.1016/j.ydbio.2018.04.020. Epub 2018 Apr 26.

4.

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.

Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A.

Dev Cell. 2017 May 22;41(4):349-365.e3. doi: 10.1016/j.devcel.2017.04.022.

5.

Repair after nephron ablation reveals limitations of neonatal neonephrogenesis.

Tögel F, Valerius MT, Freedman BS, Iatrino R, Grinstein M, Bonventre JV.

JCI Insight. 2017 Jan 26;2(2):e88848. doi: 10.1172/jci.insight.88848.

6.

(Re)Building a Kidney.

Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA.

J Am Soc Nephrol. 2017 May;28(5):1370-1378. doi: 10.1681/ASN.2016101077. Epub 2017 Jan 17.

7.

Human Kidney Organoids: Nephron Models of Development and Disease.

Valerius MT.

Transplantation. 2016 Jun;100(6):1171-2. doi: 10.1097/TP.0000000000001233. No abstract available.

PMID:
27203586
8.

SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration.

Masuzaki R, Zhao S, Valerius MT, Tsugawa D, Oya Y, Ray KC, Karp SJ.

J Biol Chem. 2016 Feb 12;291(7):3346-58. doi: 10.1074/jbc.M115.703264. Epub 2015 Dec 23.

9.

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.

Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV.

Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715.

10.

Nephron organoids derived from human pluripotent stem cells model kidney development and injury.

Morizane R, Lam AQ, Freedman BS, Kishi S, Valerius MT, Bonventre JV.

Nat Biotechnol. 2015 Nov;33(11):1193-200.

11.

IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.

Baek JH, Zeng R, Weinmann-Menke J, Valerius MT, Wada Y, Ajay AK, Colonna M, Kelley VR.

J Clin Invest. 2015 Aug 3;125(8):3198-214. doi: 10.1172/JCI81166. Epub 2015 Jun 29.

12.

Node retraction during patterning of the urinary collecting duct system.

Lindström NO, Chang CH, Valerius MT, Hohenstein P, Davies JA.

J Anat. 2015 Jan;226(1):13-21. doi: 10.1111/joa.12239. Epub 2014 Oct 8.

13.

Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.

Lam AQ, Freedman BS, Morizane R, Lerou PH, Valerius MT, Bonventre JV.

J Am Soc Nephrol. 2014 Jun;25(6):1211-25. doi: 10.1681/ASN.2013080831. Epub 2013 Dec 19.

14.

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM.

Front Neurosci. 2012 Sep 12;6:130. doi: 10.3389/fnins.2012.00130. eCollection 2012.

15.

Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks.

Park JS, Ma W, O'Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon JA, Wong WH, McMahon AP.

Dev Cell. 2012 Sep 11;23(3):637-51. doi: 10.1016/j.devcel.2012.07.008. Epub 2012 Aug 16.

16.

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.

Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP.

Development. 2012 May;139(10):1863-73. doi: 10.1242/dev.074005.

17.

Orphan nuclear receptor Nur77 promotes acute kidney injury and renal epithelial apoptosis.

Balasubramanian S, Jansen M, Valerius MT, Humphreys BD, Strom TB.

J Am Soc Nephrol. 2012 Apr;23(4):674-86. doi: 10.1681/ASN.2011070646. Epub 2012 Feb 16.

18.

Bowman's β-catenin.

Valerius MT.

J Am Soc Nephrol. 2012 Jan;23(1):3-4. doi: 10.1681/ASN.2011111106. Epub 2011 Dec 8. No abstract available.

19.

Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells.

Boyle SC, Kim M, Valerius MT, McMahon AP, Kopan R.

Development. 2011 Oct;138(19):4245-54. doi: 10.1242/dev.070433. Epub 2011 Aug 18.

20.

The rejection barrier to induced pluripotent stem cells.

Balasubramanian S, Kota SK, Valerius MT.

J Am Soc Nephrol. 2011 Sep;22(9):1583-6. doi: 10.1681/ASN.2011070707. Epub 2011 Aug 11. No abstract available.

21.

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney.

Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J.

Kidney Int. 2011 Feb;79(3):317-30. doi: 10.1038/ki.2010.385. Epub 2010 Oct 13.

22.

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis.

Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS.

Am J Pathol. 2010 Jan;176(1):85-97. doi: 10.2353/ajpath.2010.090517. Epub 2009 Dec 11.

23.

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.

Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH.

Dev Biol. 2009 Aug 15;332(2):273-86. doi: 10.1016/j.ydbio.2009.05.578. Epub 2009 Jun 6.

24.

Atlas of gene expression in the developing kidney at microanatomic resolution.

Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS.

Dev Cell. 2008 Nov;15(5):781-91. doi: 10.1016/j.devcel.2008.09.007. Erratum in: Dev Cell. 2009 Mar;16(3):482. Yu, Jing [added].

25.

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development.

Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP.

Cell Stem Cell. 2008 Aug 7;3(2):169-81. doi: 10.1016/j.stem.2008.05.020.

26.

Intrinsic epithelial cells repair the kidney after injury.

Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV.

Cell Stem Cell. 2008 Mar 6;2(3):284-91. doi: 10.1016/j.stem.2008.01.014.

27.

Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation.

Valerius MT, McMahon AP.

Gene Expr Patterns. 2008 May;8(5):297-306. doi: 10.1016/j.gep.2008.02.001. Epub 2008 Feb 9.

28.

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.

Park JS, Valerius MT, McMahon AP.

Development. 2007 Jul;134(13):2533-9. Epub 2007 May 30.

29.

A high-resolution anatomical ontology of the developing murine genitourinary tract.

Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, Beverdam A, Bertram JF, Capel B, Chiu HS, Clements D, Cullen-McEwen L, Fleming J, Gilbert T, Herzlinger D, Houghton D, Kaufman MH, Kleymenova E, Koopman PA, Lewis AG, McMahon AP, Mendelsohn CL, Mitchell EK, Rumballe BA, Sweeney DE, Valerius MT, Yamada G, Yang Y, Yu J.

Gene Expr Patterns. 2007 Jun;7(6):680-99. Epub 2007 Mar 23. Erratum in: Gene Expr Patterns. 2007 Dec;8(1):47-50.

30.

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R.

Development. 2007 Feb;134(4):801-11. Epub 2007 Jan 17.

31.

Mouse brain organization revealed through direct genome-scale TF expression analysis.

Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q.

Science. 2004 Dec 24;306(5705):2255-7.

32.

Recent genetic studies of mouse kidney development.

Yu J, McMahon AP, Valerius MT.

Curr Opin Genet Dev. 2004 Oct;14(5):550-7. Review.

PMID:
15380247
33.

Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.

Valerius MT, Patterson LT, Feng Y, Potter SS.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8090-5.

34.

Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation.

Valerius MT, Patterson LT, Witte DP, Potter SS.

Mech Dev. 2002 Mar;112(1-2):219-32.

35.

Using progenitor cells and gene chips to define genetic pathways.

Potter SS, Valerius MT, Brunskill EW.

Methods Mol Biol. 2002;185:269-84. Review. No abstract available.

PMID:
11768995
36.

Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation.

Valerius MT, Patterson LT, Witte DP, Potter SS.

Mech Dev. 2002 Jan;110(1-2):151-64. Corrected and republished in: Mech Dev. 2002 Mar;112(1-2):219-32.

37.

Spx1, a novel X-linked homeobox gene expressed during spermatogenesis.

Branford WW, Zhao GQ, Valerius MT, Weinstein M, Birkenmeier EH, Rowe LB, Potter SS.

Mech Dev. 1997 Jul;65(1-2):87-98.

38.

An enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymus.

Haynes TL, Thomas MB, Dusing MR, Valerius MT, Potter SS, Wiginton DA.

Nucleic Acids Res. 1996 Dec 15;24(24):5034-44.

39.

Gsh-1, an orphan Hox gene, is required for normal pituitary development.

Li H, Zeitler PS, Valerius MT, Small K, Potter SS.

EMBO J. 1996 Feb 15;15(4):714-24.

40.

Gsh-1: a novel murine homeobox gene expressed in the central nervous system.

Valerius MT, Li H, Stock JL, Weinstein M, Kaur S, Singh G, Potter SS.

Dev Dyn. 1995 Jul;203(3):337-51.

41.

Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequences.

Aronow BJ, Ebert CA, Valerius MT, Potter SS, Wiginton DA, Witte DP, Hutton JJ.

Mol Cell Biol. 1995 Feb;15(2):1123-35.

42.

A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy.

Kern MJ, Witte DP, Valerius MT, Aronow BJ, Potter SS.

Nucleic Acids Res. 1992 Oct 11;20(19):5189-95.

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