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Items: 1 to 50 of 197

1.

Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens.

Vigneron A, O'Neill MB, Weiss BL, Savage AF, Campbell OC, Kamhawi S, Valenzuela JG, Aksoy S.

Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2613-2621. doi: 10.1073/pnas.1914423117. Epub 2020 Jan 21.

2.

Amine-binding properties of salivary yellow-related proteins in phlebotomine sand flies.

Sumova P, Sima M, Kalouskova B, Polanska N, Vanek O, Oliveira F, Valenzuela JG, Volf P.

Insect Biochem Mol Biol. 2019 Dec;115:103245. doi: 10.1016/j.ibmb.2019.103245. Epub 2019 Oct 8.

3.

Corrigendum: Immunization of Experimental Dogs With Salivary Proteins From Lutzomyia longipalpis, Using DNA and Recombinant Canarypox Virus Induces Immune Responses Consistent With Protection Against Leishmania infantum.

Abbehusen MMC, Cunha J, Suarez MS, Teixeira C, Almeida VDA, Pereira LDS, Bordoni M, Gil-Santana L, Solcà MDS, Fraga DBM, Fischer L, Bozza PT, Veras PST, Valenzuela JG, Kamhawi S, Andrade BB, Brodskyn CI.

Front Immunol. 2019 Aug 12;10:1828. doi: 10.3389/fimmu.2019.01828. eCollection 2019.

4.

Correction: DNA plasmid coding for Phlebotomus sergenti salivary protein PsSP9, a member of the SP15 family of proteins, protects against Leishmania tropica.

Gholami E, Oliveira F, Taheri T, Seyed N, Gharibzadeh S, Gholami N, Mizbani A, Zali F, Habibzadeh S, Bakhadj DO, Meneses C, Kamyab-Hesari K, Sadeghipour A, Taslimi Y, Khadir F, Kamhawi S, Mazlomi MA, Valenzuela JG, Rafati S.

PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007585. doi: 10.1371/journal.pntd.0007585. eCollection 2019 Jul.

5.

RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus.

Araujo RN, Silva NCS, Mendes-Sousa A, Paim R, Costa GCA, Dias LR, Oliveira K, Sant'Anna MRV, Gontijo NF, Pereira MH, Pessoa GD, Valenzuela JG, Koerich LB, Oliveira F.

Sci Rep. 2019 May 1;9(1):6764. doi: 10.1038/s41598-019-42899-z.

6.

Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes.

Jablonka W, Kim IH, Alvarenga PH, Valenzuela JG, Ribeiro JMC, Andersen JF.

Sci Rep. 2019 Mar 29;9(1):5340. doi: 10.1038/s41598-019-41848-0.

7.

DNA plasmid coding for Phlebotomus sergenti salivary protein PsSP9, a member of the SP15 family of proteins, protects against Leishmania tropica.

Gholami E, Oliveira F, Taheri T, Seyed N, Gharibzadeh S, Gholami N, Mizbani A, Zali F, Habibzadeh S, Bakhadj DO, Meneses C, Kamyab-Hesari K, Sadeghipour A, Taslimi Y, Khadir F, Kamhawi S, Mazlomi MA, Valenzuela JG, Rafati S.

PLoS Negl Trop Dis. 2019 Jan 11;13(1):e0007067. doi: 10.1371/journal.pntd.0007067. eCollection 2019 Jan. Erratum in: PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007585.

8.

Coinfection With Trypanosoma brucei Confers Protection Against Cutaneous Leishmaniasis.

Pereira L, Oliveira F, Townsend S, Metangmo S, Meneses C, Moore IN, Brodskyn CI, Valenzuela JG, Magez S, Kamhawi S.

Front Immunol. 2018 Dec 11;9:2855. doi: 10.3389/fimmu.2018.02855. eCollection 2018.

9.

The PAGODAS protocol: pediatric assessment group of dengue and Aedes saliva protocol to investigate vector-borne determinants of Aedes-transmitted arboviral infections in Cambodia.

Manning JE, Oliveira F, Parker DM, Amaratunga C, Kong D, Man S, Sreng S, Lay S, Nang K, Kimsan S, Sokha L, Kamhawi S, Fay MP, Suon S, Ruhl P, Ackerman H, Huy R, Wellems TE, Valenzuela JG, Leang R.

Parasit Vectors. 2018 Dec 20;11(1):664. doi: 10.1186/s13071-018-3224-7.

10.

Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites.

Luz NF, DeSouza-Vieira T, De Castro W, Vivarini AC, Pereira L, França RR, Silveira-Mattos PS, Costa DL, Teixeira C, Meneses C, Boaventura VS, de Oliveira CI, Lopes UG, Aronson N, Andrade BB, Brodskyn CI, Valenzuela JG, Kamhawi S, Borges VM.

Front Immunol. 2018 Nov 28;9:2779. doi: 10.3389/fimmu.2018.02779. eCollection 2018.

11.

Immunization of Experimental Dogs With Salivary Proteins From Lutzomyia longipalpis, Using DNA and Recombinant Canarypox Virus Induces Immune Responses Consistent With Protection Against Leishmania infantum.

Abbehusen MMC, Cunha J, Suarez MS, Teixeira C, Almeida VDA, Pereira LDS, Bordoni M, Gil-Santana L, Solcà MDS, Fraga DBM, Fischer L, Bozza PT, Veras PST, Valenzuela JG, Kamhawi S, Andrade BB, Brodskyn CI.

Front Immunol. 2018 Nov 16;9:2558. doi: 10.3389/fimmu.2018.02558. eCollection 2018. Erratum in: Front Immunol. 2019 Aug 12;10:1828.

12.

Human antibody reaction against recombinant salivary proteins of Phlebotomus orientalis in Eastern Africa.

Sumova P, Sima M, Spitzova T, Osman ME, Guimaraes-Costa AB, Oliveira F, Elnaiem DA, Hailu A, Warburg A, Valenzuela JG, Volf P.

PLoS Negl Trop Dis. 2018 Dec 4;12(12):e0006981. doi: 10.1371/journal.pntd.0006981. eCollection 2018 Dec.

13.

The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector.

Bourret TJ, Boyle WK, Zalud AK, Valenzuela JG, Oliveira F, Lopez JE.

Cell Microbiol. 2019 Feb;21(2):e12987. doi: 10.1111/cmi.12987. Epub 2019 Jan 4.

14.

Comparative Evolution of Sand Fly Salivary Protein Families and Implications for Biomarkers of Vector Exposure and Salivary Vaccine Candidates.

Coutinho-Abreu IV, Valenzuela JG.

Front Cell Infect Microbiol. 2018 Aug 29;8:290. doi: 10.3389/fcimb.2018.00290. eCollection 2018.

15.

Antibody targeting of a specific region of Pfs47 blocks Plasmodium falciparum malaria transmission.

Canepa GE, Molina-Cruz A, Yenkoidiok-Douti L, Calvo E, Williams AE, Burkhardt M, Peng F, Narum D, Boulanger MJ, Valenzuela JG, Barillas-Mury C.

NPJ Vaccines. 2018 Jul 10;3:26. doi: 10.1038/s41541-018-0065-5. eCollection 2018.

16.

Impact of vector biology research on old and emerging neglected tropical diseases.

Valenzuela JG, Aksoy S.

PLoS Negl Trop Dis. 2018 May 31;12(5):e0006365. doi: 10.1371/journal.pntd.0006365. eCollection 2018 May. No abstract available.

17.

Immunity to LuloHya and Lundep, the salivary spreading factors from Lutzomyia longipalpis, protects against Leishmania major infection.

Martin-Martin I, Chagas AC, Guimaraes-Costa AB, Amo L, Oliveira F, Moore IN, DeSouza-Vieira TS, Sanchez EE, Suntravat M, Valenzuela JG, Ribeiro JMC, Calvo E.

PLoS Pathog. 2018 May 3;14(5):e1007006. doi: 10.1371/journal.ppat.1007006. eCollection 2018 May.

18.

Mosquito Saliva: The Hope for a Universal Arbovirus Vaccine?

Manning JE, Morens DM, Kamhawi S, Valenzuela JG, Memoli M.

J Infect Dis. 2018 Jun 5;218(1):7-15. doi: 10.1093/infdis/jiy179. Review.

19.

Sequential blood meals promote Leishmania replication and reverse metacyclogenesis augmenting vector infectivity.

Serafim TD, Coutinho-Abreu IV, Oliveira F, Meneses C, Kamhawi S, Valenzuela JG.

Nat Microbiol. 2018 May;3(5):548-555. doi: 10.1038/s41564-018-0125-7. Epub 2018 Mar 19.

20.

Ticks, Ixodes scapularis, Feed Repeatedly on White-Footed Mice despite Strong Inflammatory Response: An Expanding Paradigm for Understanding Tick-Host Interactions.

Anderson JM, Moore IN, Nagata BM, Ribeiro JMC, Valenzuela JG, Sonenshine DE.

Front Immunol. 2017 Dec 18;8:1784. doi: 10.3389/fimmu.2017.01784. eCollection 2017.

21.

A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali.

Sangare MB, Coulibaly YI, Coulibaly SY, Coulibaly ME, Traore B, Dicko I, Sissoko IM, Samake S, Traore SF, Nutman TB, Valenzuela JG, Faye O, Kamhawi S, Oliveira F, Semnani RT, Doumbia S.

Parasit Vectors. 2018 Jan 8;11(1):18. doi: 10.1186/s13071-017-2531-8.

22.

Gut Microbes Egested during Bites of Infected Sand Flies Augment Severity of Leishmaniasis via Inflammasome-Derived IL-1β.

Dey R, Joshi AB, Oliveira F, Pereira L, Guimarães-Costa AB, Serafim TD, de Castro W, Coutinho-Abreu IV, Bhattacharya P, Townsend S, Aslan H, Perkins A, Karmakar S, Ismail N, Karetnick M, Meneses C, Duncan R, Nakhasi HL, Valenzuela JG, Kamhawi S.

Cell Host Microbe. 2018 Jan 10;23(1):134-143.e6. doi: 10.1016/j.chom.2017.12.002. Epub 2017 Dec 28.

23.

A defined subunit vaccine that protects against vector-borne visceral leishmaniasis.

Duthie MS, Pereira L, Favila M, Hofmeyer KA, Reed SJ, Metangmo S, Townsend S, Laurance JD, Picone A, Misquith A, Hossain F, Ghosh P, Khan MAA, Guderian J, Bailor HR, Liang H, Vergara J, Oliveira F, Howard RF, Kamhawi S, Mondal D, Coler RN, Valenzuela JG, Reed SG.

NPJ Vaccines. 2017 Aug 21;2:23. doi: 10.1038/s41541-017-0025-5. eCollection 2017.

24.

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis.

Cecílio P, Pérez-Cabezas B, Fernández L, Moreno J, Carrillo E, Requena JM, Fichera E, Reed SG, Coler RN, Kamhawi S, Oliveira F, Valenzuela JG, Gradoni L, Glueck R, Gupta G, Cordeiro-da-Silva A.

PLoS Negl Trop Dis. 2017 Nov 27;11(11):e0005951. doi: 10.1371/journal.pntd.0005951. eCollection 2017 Nov.

25.

Inhibition of the complement system by saliva of Anopheles (Nyssorhynchus) aquasalis.

Mendes-Sousa AF, Vale VF, Queiroz DC, Pereira-Filho AA, da Silva NCS, Koerich LB, Moreira LA, Pereira MH, Sant'Anna MR, Araújo RN, Andersen J, Valenzuela JG, Gontijo NF.

Insect Biochem Mol Biol. 2018 Jan;92:12-20. doi: 10.1016/j.ibmb.2017.11.004. Epub 2017 Nov 8.

26.

Phlebotomus papatasi Yellow-Related and Apyrase Salivary Proteins Are Candidates for Vaccination against Human Cutaneous Leishmaniasis.

Tlili A, Marzouki S, Chabaane E, Abdeladhim M, Kammoun-Rebai W, Sakkouhi R, Belhadj Hmida N, Oliveira F, Kamhawi S, Louzir H, Valenzuela JG, Ben Ahmed M.

J Invest Dermatol. 2018 Mar;138(3):598-606. doi: 10.1016/j.jid.2017.09.043. Epub 2017 Oct 17.

27.

Salivary lipocalin family proteins from Panstrongylus chinai, a vector of Chagas disease.

Kato H, Jochim RC, Gomez EA, Tsunekawa S, Valenzuela JG, Hashiguchi Y.

Data Brief. 2017 Sep 22;15:272-280. doi: 10.1016/j.dib.2017.09.039. eCollection 2017 Dec.

28.

Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4.

Matus V, Valenzuela JG, Hidalgo P, Pozo LM, Panes O, Wozniak A, Mezzano D, Pereira J, Sáez CG.

PLoS One. 2017 Sep 28;12(9):e0185431. doi: 10.1371/journal.pone.0185431. eCollection 2017.

29.

High-Sensitivity Assays for Plasmodium falciparum Infection by Immuno-Polymerase Chain Reaction Detection of PfIDEh and PfLDH Antigens.

Mu J, Andersen JF, Valenzuela JG, Wellems TE.

J Infect Dis. 2017 Sep 15;216(6):713-722. doi: 10.1093/infdis/jix369.

30.

The Sand Fly Salivary Protein Lufaxin Inhibits the Early Steps of the Alternative Pathway of Complement by Direct Binding to the Proconvertase C3b-B.

Mendes-Sousa AF, do Vale VF, Silva NCS, Guimaraes-Costa AB, Pereira MH, Sant'Anna MRV, Oliveira F, Kamhawi S, Ribeiro JMC, Andersen JF, Valenzuela JG, Araujo RN.

Front Immunol. 2017 Aug 31;8:1065. doi: 10.3389/fimmu.2017.01065. eCollection 2017.

31.

Salivary gland transcripts of the kissing bug, Panstrongylus chinai, a vector of Chagas disease.

Kato H, Jochim RC, Gomez EA, Tsunekawa S, Valenzuela JG, Hashiguchi Y.

Acta Trop. 2017 Oct;174:122-129. doi: 10.1016/j.actatropica.2017.06.022. Epub 2017 Jul 6.

32.

Seroconversion to Lutzomyia intermedia LinB-13 as a biomarker for developing cutaneous leishmaniasis.

Carvalho AM, Fukutani KF, Sharma R, Curvelo RP, Miranda JC, Barral A, Carvalho EM, Valenzuela JG, Oliveira F, de Oliveira CI.

Sci Rep. 2017 Jun 9;7(1):3149. doi: 10.1038/s41598-017-03345-0.

33.

Mining a differential sialotranscriptome of Rhipicephalus microplus guides antigen discovery to formulate a vaccine that reduces tick infestations.

Maruyama SR, Garcia GR, Teixeira FR, Brandão LG, Anderson JM, Ribeiro JMC, Valenzuela JG, Horackova J, Veríssimo CJ, Katiki LM, Banin TM, Zangirolamo AF, Gardinassi LG, Ferreira BR, de Miranda-Santos IKF.

Parasit Vectors. 2017 Apr 26;10(1):206. doi: 10.1186/s13071-017-2136-2.

34.

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.

Roatt BM, Aguiar-Soares RD, Reis LE, Cardoso JM, Mathias FA, de Brito RC, da Silva SM, Gontijo NF, Ferreira SA, Valenzuela JG, Corrêa-Oliveira R, Giunchetti RC, Reis AB.

Front Immunol. 2017 Mar 7;8:217. doi: 10.3389/fimmu.2017.00217. eCollection 2017.

35.

Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.

Asojo OA, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, Abdeladhim M, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, Hotez PJ, Zhan B, Oliveira F, Kamhawi S, Valenzuela JG.

PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005374. doi: 10.1371/journal.pntd.0005374. eCollection 2017 Mar.

36.

Correction: Prevalence of Cutaneous Leishmaniasis in Districts of High and Low Endemicity in Mali.

Traoré B, Oliveira F, Faye O, Dicko A, Coulibaly CA, Sissoko IM, Sibiry S, Sogoba N, Sangare MB, Coulibaly YI, Traore P, Traore SF, Anderson JM, Keita S, Valenzuela JG, Kamhawi S, Doumbia S.

PLoS Negl Trop Dis. 2017 Feb 15;11(2):e0005379. doi: 10.1371/journal.pntd.0005379. eCollection 2017 Feb.

37.

The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum.

Kelly PH, Bahr SM, Serafim TD, Ajami NJ, Petrosino JF, Meneses C, Kirby JR, Valenzuela JG, Kamhawi S, Wilson ME.

mBio. 2017 Jan 17;8(1). pii: e01121-16. doi: 10.1128/mBio.01121-16.

38.

Prevalence of Cutaneous Leishmaniasis in Districts of High and Low Endemicity in Mali.

Traoré B, Oliveira F, Faye O, Dicko A, Coulibaly CA, Sissoko IM, Sibiry S, Sogoba N, Sangare MB, Coulibaly YI, Traore P, Traore SF, Anderson JM, Keita S, Valenzuela JG, Kamhawi S, Doumbia S.

PLoS Negl Trop Dis. 2016 Nov 29;10(11):e0005141. doi: 10.1371/journal.pntd.0005141. eCollection 2016 Nov. Erratum in: PLoS Negl Trop Dis. 2017 Feb 15;11(2):e0005379.

39.

Circulating Biomarkers of Immune Activation, Oxidative Stress and Inflammation Characterize Severe Canine Visceral Leishmaniasis.

Solcà MS, Andrade BB, Abbehusen MM, Teixeira CR, Khouri R, Valenzuela JG, Kamhawi S, Bozza PT, Fraga DB, Borges VM, Veras PS, Brodskyn CI.

Sci Rep. 2016 Sep 6;6:32619. doi: 10.1038/srep32619.

40.

Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways.

Silva NC, Vale VF, Franco PF, Gontijo NF, Valenzuela JG, Pereira MH, Sant'Anna MR, Rodrigues DS, Lima WS, Fux B, Araujo RN.

Parasit Vectors. 2016 Aug 11;9(1):445. doi: 10.1186/s13071-016-1726-8.

41.

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica.

Abdeladhim M, V Coutinho-Abreu I, Townsend S, Pasos-Pinto S, Sanchez L, Rasouli M, B Guimaraes-Costa A, Aslan H, Francischetti IM, Oliveira F, Becker I, Kamhawi S, Ribeiro JM, Jochim RC, Valenzuela JG.

PLoS Negl Trop Dis. 2016 Jul 13;10(7):e0004771. doi: 10.1371/journal.pntd.0004771. eCollection 2016 Jul.

42.

Non-infectious environmental antigens as a trigger for the initiation of an autoimmune skin disease.

Qian Y, Culton DA, Jeong JS, Trupiano N, Valenzuela JG, Diaz LA.

Autoimmun Rev. 2016 Sep;15(9):923-30. doi: 10.1016/j.autrev.2016.07.005. Epub 2016 Jul 8. Review.

43.

Differential expression profiles of the salivary proteins SP15 and SP44 from Phlebotomus papatasi.

Hosseini-Vasoukolaei N, Idali F, Khamesipour A, Yaghoobi-Ershadi MR, Kamhawi S, Valenzuela JG, Edalatkhah H, Arandian MH, Mirhendi H, Emami S, Jafari R, Saeidi Z, Jeddi-Tehrani M, Akhavan AA.

Parasit Vectors. 2016 Jun 24;9(1):357. doi: 10.1186/s13071-016-1633-z.

44.

An Inhibitor of the Alternative Pathway of Complement in Saliva of New World Anopheline Mosquitoes.

Mendes-Sousa AF, Queiroz DC, Vale VF, Ribeiro JM, Valenzuela JG, Gontijo NF, Andersen JF.

J Immunol. 2016 Jul 15;197(2):599-610. doi: 10.4049/jimmunol.1600020. Epub 2016 Jun 15.

45.

Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood.

Blatt AZ, Saggu G, Kulkarni KV, Cortes C, Thurman JM, Ricklin D, Lambris JD, Valenzuela JG, Ferreira VP.

J Immunol. 2016 Jun 1;196(11):4671-4680. doi: 10.4049/jimmunol.1600040. Epub 2016 Apr 25.

46.

Seasonal and Physiological Variations of Phlebotomus papatasi Salivary Gland Antigens in Central Iran.

Hosseini-Vasoukolaei N, Mahmoudi AR, Khamesipour A, Yaghoobi-Ershadi MR, Kamhawi S, Valenzuela JG, Arandian MH, Mirhendi H, Emami S, Saeidi Z, Idali F, Jafari R, Jeddi-Tehrani M, Akhavan AA.

J Arthropod Borne Dis. 2015 Jun 27;10(1):39-49. eCollection 2016 Mar.

47.

Inhibition of the classical pathway of the complement system by saliva of Amblyomma cajennense (Acari: Ixodidae).

Franco PF, Silva NC, Fazito do Vale V, Abreu JF, Santos VC, Gontijo NF, Valenzuela JG, Pereira MH, Sant'Anna MR, Gomes AP, Araujo RN.

Exp Parasitol. 2016 May;164:91-6. doi: 10.1016/j.exppara.2016.03.002. Epub 2016 Mar 3.

48.

Overlapping IgG4 Responses to Self- and Environmental Antigens in Endemic Pemphigus Foliaceus.

Qian Y, Jeong JS, Ye J, Dang B, Abdeladhim M, Aoki V, Hans-Filhio G, Rivitti EA, Valenzuela JG, Diaz LA.

J Immunol. 2016 Mar 1;196(5):2041-50. doi: 10.4049/jimmunol.1502233. Epub 2016 Jan 29.

49.

New Insights Into the Transmissibility of Leishmania infantum From Dogs to Sand Flies: Experimental Vector-Transmission Reveals Persistent Parasite Depots at Bite Sites.

Aslan H, Oliveira F, Meneses C, Castrovinci P, Gomes R, Teixeira C, Derenge CA, Orandle M, Gradoni L, Oliva G, Fischer L, Valenzuela JG, Kamhawi S.

J Infect Dis. 2016 Jun 1;213(11):1752-61. doi: 10.1093/infdis/jiw022. Epub 2016 Jan 14.

50.

SALO, a novel classical pathway complement inhibitor from saliva of the sand fly Lutzomyia longipalpis.

Ferreira VP, Fazito Vale V, Pangburn MK, Abdeladhim M, Mendes-Sousa AF, Coutinho-Abreu IV, Rasouli M, Brandt EA, Meneses C, Lima KF, Nascimento Araújo R, Pereira MH, Kotsyfakis M, Oliveira F, Kamhawi S, Ribeiro JM, Gontijo NF, Collin N, Valenzuela JG.

Sci Rep. 2016 Jan 13;6:19300. doi: 10.1038/srep19300.

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