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Items: 1 to 50 of 82

1.

Capsaicinoids: Multiple effects on angiogenesis, invasion and metastasis in human cancers.

Friedman JR, Richbart SD, Merritt JC, Brown KC, Denning KL, Tirona MT, Valentovic MA, Miles SL, Dasgupta P.

Biomed Pharmacother. 2019 Aug 9;118:109317. doi: 10.1016/j.biopha.2019.109317. [Epub ahead of print] Review.

2.

Capsaicinoids enhance chemosensitivity to chemotherapeutic drugs.

Friedman JR, Richbart SD, Merritt JC, Perry HE, Brown KC, Akers AT, Nolan NA, Stevenson CD, Hurley JD, Miles SL, Tirona MT, Valentovic MA, Dasgupta P.

Adv Cancer Res. 2019;144:263-298. doi: 10.1016/bs.acr.2019.05.002.

PMID:
31349900
3.

Contrast Induced Acute Kidney Injury and Direct Cytotoxicity of Iodinated Radiocontrast Media on Renal Proximal Tubule Cells.

Ward DB, Valentovic MA.

J Pharmacol Exp Ther. 2019 Aug;370(2):160-171. doi: 10.1124/jpet.119.257337. Epub 2019 May 17.

PMID:
31101680
4.

Rural and urban differences in prenatal exposure to essential and toxic elements.

Cottrell JN, Thomas DS, Mitchell BL, Childress JE, Dawley DM, Harbrecht LE, Jude DA, Valentovic MA.

J Toxicol Environ Health A. 2018;81(23):1214-1223. doi: 10.1080/15287394.2018.1547890. Epub 2018 Nov 22.

PMID:
30465633
5.

Historical Perspective of Nephrotoxicity.

Rankin GO, Valentovic MA.

Toxicol Sci. 2018 Aug 1;164(2):377-378. doi: 10.1093/toxsci/kfy169. Review. No abstract available.

6.

Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics.

Ahmad T, Valentovic MA, Rankin GO.

Biochem Pharmacol. 2018 Jul;153:196-204. doi: 10.1016/j.bcp.2018.02.020. Epub 2018 Feb 16. Review.

7.

Evaluation of Resveratrol in Cancer Patients and Experimental Models.

Valentovic MA.

Adv Cancer Res. 2018;137:171-188. doi: 10.1016/bs.acr.2017.11.006. Epub 2017 Dec 15.

PMID:
29405976
8.

Anticancer Activity of Natural and Synthetic Capsaicin Analogs.

Friedman JR, Nolan NA, Brown KC, Miles SL, Akers AT, Colclough KW, Seidler JM, Rimoldi JM, Valentovic MA, Dasgupta P.

J Pharmacol Exp Ther. 2018 Mar;364(3):462-473. doi: 10.1124/jpet.117.243691. Epub 2017 Dec 15. Review.

9.

Factors Contributing to the Antiviral Effectiveness of Tenofovir.

Murphy RA, Valentovic MA.

J Pharmacol Exp Ther. 2017 Nov;363(2):156-163. doi: 10.1124/jpet.117.243139. Epub 2017 Aug 31. Review.

PMID:
28860352
10.

Role of Free Radicals and Biotransformation in Trichloronitrobenzene-Induced Nephrotoxicity In Vitro.

Rankin GO, Tyree C, Pope D, Tate J, Racine C, Anestis DK, Brown KC, Dial M, Valentovic MA.

Int J Mol Sci. 2017 May 31;18(6). pii: E1165. doi: 10.3390/ijms18061165.

11.

Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity.

Murphy RA, Stafford RM, Petrasovits BA, Boone MA, Valentovic MA.

Int J Mol Sci. 2017 Mar 1;18(3). pii: E531. doi: 10.3390/ijms18030531.

12.

Bioavailability of capsaicin and its implications for drug delivery.

Rollyson WD, Stover CA, Brown KC, Perry HE, Stevenson CD, McNees CA, Ball JG, Valentovic MA, Dasgupta P.

J Control Release. 2014 Dec 28;196:96-105. doi: 10.1016/j.jconrel.2014.09.027. Epub 2014 Oct 12. Review.

13.

S-adenosyl-l-methionine protection of acetaminophen mediated oxidative stress and identification of hepatic 4-hydroxynonenal protein adducts by mass spectrometry.

Brown JM, Kuhlman C, Terneus MV, Labenski MT, Lamyaithong AB, Ball JG, Lau SS, Valentovic MA.

Toxicol Appl Pharmacol. 2014 Dec 1;281(2):174-84. doi: 10.1016/j.taap.2014.08.027. Epub 2014 Sep 22.

14.

Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway.

Lau JK, Brown KC, Dom AM, Witte TR, Thornhill BA, Crabtree CM, Perry HE, Brown JM, Ball JG, Creel RG, Damron CL, Rollyson WD, Stevenson CD, Hardman WE, Valentovic MA, Carpenter AB, Dasgupta P.

Apoptosis. 2014 Aug;19(8):1190-201. doi: 10.1007/s10495-014-1007-y.

15.

Transsulfuration Is a Significant Source of Sulfur for Glutathione Production in Human Mammary Epithelial Cells.

Belalcázar AD, Ball JG, Frost LM, Valentovic MA, Wilkinson J 4th.

ISRN Biochem. 2014;2013:637897.

16.

Resveratrol attenuates cisplatin renal cortical cytotoxicity by modifying oxidative stress.

Valentovic MA, Ball JG, Brown JM, Terneus MV, McQuade E, Van Meter S, Hedrick HM, Roy AA, Williams T.

Toxicol In Vitro. 2014 Mar;28(2):248-57. doi: 10.1016/j.tiv.2013.11.001. Epub 2013 Nov 12.

17.

Role of leukotrienes in N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity in male Fischer 344 rats.

Rankin GO, Hong SK, Anestis DK, Ball JG, Valentovic MA, Graffeo VA.

Toxicology. 2012 Oct 9;300(1-2):92-9. doi: 10.1016/j.tox.2012.06.003. Epub 2012 Jun 15.

18.

Novel protective mechanisms for S-adenosyl-L-methionine against acetaminophen hepatotoxicity: improvement of key antioxidant enzymatic function.

Michael Brown J, Ball JG, Wright MS, Van Meter S, Valentovic MA.

Toxicol Lett. 2012 Aug 3;212(3):320-8. doi: 10.1016/j.toxlet.2012.05.018. Epub 2012 Jun 5.

19.

Characterization of a novel model for investigation of radiocontrast nephrotoxicity.

Harmon RC, Duffy SP, Terneus MV, Ball JG, Valentovic MA.

Nephrol Dial Transplant. 2009 Mar;24(3):763-8. doi: 10.1093/ndt/gfn540. Epub 2008 Oct 7.

PMID:
18840895
20.

Mechanistic aspects of 4-amino-2,6-dichlorophenol-induced in vitro nephrotoxicity.

Rankin GO, Hong SK, Anestis DK, Ball JG, Valentovic MA.

Toxicology. 2008 Mar 12;245(1-2):123-9. doi: 10.1016/j.tox.2007.12.014. Epub 2007 Dec 27.

PMID:
18243470
21.
22.

Nephrotoxicity induced by the R- and S-enantiomers of N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and their sulfate conjugates in male Fischer 344 rats.

Rankin GO, Anestis DK, Valentovic MA, Sun H, Triest WE.

Toxicology. 2007 Oct 30;240(1-2):38-47. Epub 2007 Jul 20.

23.

Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity.

Terneus MV, Kiningham KK, Carpenter AB, Sullivan SB, Valentovic MA.

J Pharmacol Exp Ther. 2007 Jan;320(1):99-107. Epub 2006 Oct 25.

PMID:
17065366
24.

Streptozotocin (STZ) diabetes enhances benzo(alpha)pyrene induced renal injury in Sprague Dawley rats.

Valentovic MA, Alejandro N, Betts Carpenter A, Brown PI, Ramos K.

Toxicol Lett. 2006 Jul 14;164(3):214-20. Epub 2006 Feb 7.

PMID:
16460892
25.

Pyruvate reduces 4-aminophenol in vitro toxicity.

Harmon RC, Kiningham KK, Valentovic MA.

Toxicol Appl Pharmacol. 2006 Jun 1;213(2):179-86. Epub 2005 Dec 15.

PMID:
16343575
26.

Pyruvate attenuates myoglobin in vitro toxicity.

Valentovic MA, Minigh J.

Toxicol Sci. 2003 Aug;74(2):345-51. Epub 2003 May 28.

PMID:
12773762
27.

Characterization of myoglobin toxicity in renal cortical slices from Fischer 344 rats.

Minigh JL, Valentovic MA.

Toxicology. 2003 May 1;187(1):77-87.

PMID:
12679054
28.

Characterization of myoglobin toxicity in renal cortical slices from Fischer 344 rats.

Minigh JL, Valentovic MA.

Toxicology. 2003 Mar 3;184(2-3):113-23. Erratum in: Toxicology. 2003 May 1;187(1):75.

PMID:
12499114
29.

Increased sensitivity of the obese Zucker rat to deoxycorticosterone-salt-induced hypertension.

Morrison RG, Carpenter AB, Moore SK, Mangiarua EI, Valentovic MA, Walker EM Jr, Wehner PS, Rhoten WB, Touchon RC, McCumbee WD.

J Hypertens. 2002 Nov;20(11):2247-55.

PMID:
12409964
30.

Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.

Rankin GO, Hong SK, Anestis DK, Henderson TT, Ball JG, Valentovic MA, Brown PI.

J Toxicol Environ Health A. 2002 Apr 12;65(7):539-56.

PMID:
11939711
31.

Characterization of 2-amino-4,5-dichlorophenol (2A45CP) in vitro toxicity in renal cortical slices from male Fischer 344 rats.

Valentovic MA, Ball JG, Sun H, Rankin GO.

Toxicology. 2002 Mar 20;172(2):113-23.

PMID:
11882351
32.

In vitro nephrotoxicity induced by chloronitrobenzenes in renal cortical slices from Fischer 344 rats.

Hong SK, Anestis DK, Ball JG, Valentovic MA, Rankin GO.

Toxicol Lett. 2002 Mar 24;129(1-2):133-41.

PMID:
11879984
33.

Role of stereochemistry in N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity.

Rankin GO, Sun H, Anestis DK, Noe O 2nd, Ball JG, Valentovic MA, Brown PI, Hubbard JL.

Toxicology. 2001 Nov 30;168(3):241-50.

PMID:
11684321
34.

Gender differences in the potentiation of N-(3,5-dichlorophenyl)succinimide metabolite nephrotoxicity by phenobarbital.

Hong SK, Anestis DK, Valentovic MA, Ball JG, Brown PI, Rankin GO.

J Toxicol Environ Health A. 2001 Oct 12;64(3):241-56.

PMID:
11594702
35.
36.

Nephrotoxic potential of N-(3,5-dichloro-4-fluorophenyl)succinimide in Fischer 344 rats: comparison with N-(3,4,5-trichlorophenyl)succinimide.

Hubbard JL, Noe O 2nd, Egermayer M, Hong SK, Anestis DK, Valentovic MA, Ball JG, Brown PI, Rankin GO.

Toxicology. 1999 Feb 15;132(2-3):127-37.

PMID:
10433376
37.

2-Aminophenol and 4-aminophenol toxicity in renal slices from Sprague-Dawley and Fischer 344 rats.

Valentovic MA, Ball JG.

J Toxicol Environ Health A. 1998 Oct 9;55(3):225-40.

PMID:
9772105
38.

Gender differences in acute N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity in Fischer 344 rats.

Hong SK, Anestis DK, Valentovic MA, Ball JG, Brown PI, Wang RT, Rankin GO.

J Toxicol Environ Health A. 1998 Aug 21;54(8):613-32.

PMID:
9726783
39.

3,4-Dicholoroaniline acute toxicity in male Fischer 344 rats.

Valentovic MA, Yahia T, Ball JG, Hong SK, Brown PI, Rankin GO.

Toxicology. 1997 Dec 26;124(2):125-34.

PMID:
9458002
40.

4-Amino-2,6-dichlorophenol nephrotoxicity in the Fischer 344 rat: protection by ascorbic acid, AT-125, and aminooxyacetic acid.

Hong SK, Anestis DK, Ball JG, Valentovic MA, Brown PI, Rankin GO.

Toxicol Appl Pharmacol. 1997 Nov;147(1):115-25.

PMID:
9356314
41.

Effects of sodium sulfate on acute N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity in the Fischer 344 rat.

Rankin GO, Hong SK, Valentovic MA, Beers KW, Anestis DK, Nicoll DW, Ball JG, Brown PI.

Toxicology. 1997 Nov 21;123(1-2):1-13.

PMID:
9347919
42.

Characterization of methemoglobin formation induced by 3,5-dichloroaniline, 4-amino-2,6-dichlorophenol and 3,5-dichlorophenylhydroxylamine.

Valentovic MA, Rogers BA, Meadows MK, Conner JT, Williams E, Hong SK, Rankin GO.

Toxicology. 1997 Mar 14;118(1):23-36.

PMID:
9074651
43.

In Vitro toxicity of 2- and 4-chloroaniline: comparisons with 4-amino-3-chlorophenol, 2-amino-5-chlorophenol and aminophenols.

Valentovic MA, Ball JG, Hong SK, Rogers BA, Meadows MK, Harmon RC, Rankin GO.

Toxicol In Vitro. 1996 Dec;10(6):713-20.

PMID:
20650255
44.

Nephrotoxicity of 4-amino-2-chlorophenol and 2-amino-4-chlorophenol in the Fischer 344 rat.

Hong SK, Valentovic MA, Anestis DK, Ball JG, Brown PI, Rankin GO.

Toxicology. 1996 Jun 17;110(1-3):47-58.

PMID:
8658559
45.

Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides.

Hong SK, Anestis DK, Hawco NM, Valentovic MA, Brown PI, Rankin GO.

Toxicology. 1996 Jun 17;110(1-3):17-25.

PMID:
8658556
46.

Comparison of cephaloridine renal accumulation and urinary excretion between normoglycemic and diabetic animals.

Valentovic MA, Ball JG, Rogers BA.

Toxicology. 1996 Apr 15;108(1-2):93-9.

PMID:
8644123
47.

Nephrotoxic potential of 2-amino-5-chlorophenol and 4-amino-3-chlorophenol in Fischer 344 rats: comparisons with 2- and 4-chloroaniline and 2- and 4-aminophenol.

Rankin GO, Beers KW, Nicoll DW, Anestis DK, Hong SK, Hubbard JL, Ball JG, Valentovic MA, Brown PI.

Toxicology. 1996 Apr 15;108(1-2):109-23.

PMID:
8644109
48.

Contractile responses and structure of small bronchi isolated from rats after 20 months' exposure to ozone.

Szarek JL, Stewart NL, Zhang JZ, Webb JA, Valentovic MA, Catalano P.

Fundam Appl Toxicol. 1995 Dec;28(2):199-208.

PMID:
8835229
49.

3,5-Dichloroaniline toxicity in Fischer 344 rats pretreated with inhibitors and inducers of cytochrome P450.

Valentovic MA, Lo HH, Brown PI, Rankin GO.

Toxicol Lett. 1995 Aug;78(3):207-14.

PMID:
7624891
50.

Effect of dimethyl sulfoxide on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity.

Rankin GO, Beers KW, Nicoll DW, Anestis DK, Ball JG, Valentovic MA, Brown PI.

Toxicology. 1995 Jun 26;100(1-3):79-88.

PMID:
7624885

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