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Items: 1 to 50 of 170


Drugs, sleep, and the addicted brain.

Valentino RJ, Volkow ND.

Neuropsychopharmacology. 2019 Jul 16. doi: 10.1038/s41386-019-0465-x. [Epub ahead of print] Review. No abstract available.


Corticotropin-Releasing Factor (CRF) circuit modulation of cognition and motivation.

Hupalo S, Bryce CA, Bangasser DA, Berridge CW, Valentino RJ, Floresco SB.

Neurosci Biobehav Rev. 2019 Aug;103:50-59. doi: 10.1016/j.neubiorev.2019.06.010. Epub 2019 Jun 15. Review.


Editorial for neurobiology of stress special issue on stress and substance abuse throughout development.

Valentino RJ.

Neurobiol Stress. 2019 Jun 3;11:100178. doi: 10.1016/j.ynstr.2019.100178. eCollection 2019 Nov. No abstract available.


Age- and sex-dependent impact of repeated social stress on morphology of rat prefrontal cortex pyramidal neurons.

Urban KR, Geng E, Bhatnagar S, Valentino RJ.

Neurobiol Stress. 2019 Apr 13;10:100165. doi: 10.1016/j.ynstr.2019.100165. eCollection 2019 Feb.


Neurochemically distinct circuitry regulates locus coeruleus activity during female social stress depending on coping style.

Reyes BAS, Zhang XY, Dufourt EC, Bhatnagar S, Valentino RJ, Van Bockstaele EJ.

Brain Struct Funct. 2019 May;224(4):1429-1446. doi: 10.1007/s00429-019-01837-5. Epub 2019 Feb 14.


Sex differences in morphine-induced trafficking of mu-opioid and corticotropin-releasing factor receptors in locus coeruleus neurons.

Enman NM, Reyes BAS, Shi Y, Valentino RJ, Van Bockstaele EJ.

Brain Res. 2019 Mar 1;1706:75-85. doi: 10.1016/j.brainres.2018.11.001. Epub 2018 Nov 2.


Untangling the complexity of opioid receptor function.

Valentino RJ, Volkow ND.

Neuropsychopharmacology. 2018 Dec;43(13):2514-2520. doi: 10.1038/s41386-018-0225-3. Epub 2018 Sep 24. Review.


Brainstem network dynamics underlying the encoding of bladder information.

Manohar A, Curtis AL, Zderic SA, Valentino RJ.

Elife. 2017 Dec 4;6. pii: e29917. doi: 10.7554/eLife.29917.


Central Network Dynamics Regulating Visceral and Humoral Functions.

Valentino RJ, Guyenet P, Hou XH, Herman M.

J Neurosci. 2017 Nov 8;37(45):10848-10854. doi: 10.1523/JNEUROSCI.1833-17.2017. Review.


Sex-biased cellular signaling: molecular basis for sex differences in neuropsychiatric diseases.

Valentino RJ, Bangasser DA.

Dialogues Clin Neurosci. 2016 Dec;18(4):385-393. Review.


Age- and Sex-Dependent Impact of Repeated Social Stress on Intrinsic and Synaptic Excitability of the Rat Prefrontal Cortex.

Urban KR, Valentino RJ.

Cereb Cortex. 2017 Jan 1;27(1):244-253. doi: 10.1093/cercor/bhw388.


Sex Differences in μ-Opioid Receptor Regulation of the Rat Locus Coeruleus and Their Cognitive Consequences.

Guajardo HM, Snyder K, Ho A, Valentino RJ.

Neuropsychopharmacology. 2017 May;42(6):1295-1304. doi: 10.1038/npp.2016.252. Epub 2016 Nov 9.


Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling.

Bangasser DA, Dong H, Carroll J, Plona Z, Ding H, Rodriguez L, McKennan C, Csernansky JG, Seeholzer SH, Valentino RJ.

Mol Psychiatry. 2017 Aug;22(8):1126-1133. doi: 10.1038/mp.2016.185. Epub 2016 Oct 18.


Individual differences in the locus coeruleus-norepinephrine system: Relevance to stress-induced cardiovascular vulnerability.

Wood CS, Valentino RJ, Wood SK.

Physiol Behav. 2017 Apr 1;172:40-48. doi: 10.1016/j.physbeh.2016.07.008. Epub 2016 Jul 14. Review.


The brain norepinephrine system, stress and cardiovascular vulnerability.

Wood SK, Valentino RJ.

Neurosci Biobehav Rev. 2017 Mar;74(Pt B):393-400. doi: 10.1016/j.neubiorev.2016.04.018. Epub 2016 Apr 27. Review.


Stress increases GABAergic neurotransmission in CRF neurons of the central amygdala and bed nucleus stria terminalis.

Partridge JG, Forcelli PA, Luo R, Cashdan JM, Schulkin J, Valentino RJ, Vicini S.

Neuropharmacology. 2016 Aug;107:239-250. doi: 10.1016/j.neuropharm.2016.03.029. Epub 2016 Mar 22.


Social Stress Engages Neurochemically-Distinct Afferents to the Rat Locus Coeruleus Depending on Coping Strategy.

Reyes BA, Zitnik G, Foster C, Van Bockstaele EJ, Valentino RJ.

eNeuro. 2015 Nov 26;2(6). pii: ENEURO.0042-15.2015. doi: 10.1523/ENEURO.0042-15.2015. eCollection 2015 Nov-Dec.


Adolescent Social Stress Produces an Enduring Activation of the Rat Locus Coeruleus and Alters its Coherence with the Prefrontal Cortex.

Zitnik GA, Curtis AL, Wood SK, Arner J, Valentino RJ.

Neuropsychopharmacology. 2016 Apr;41(5):1376-85. doi: 10.1038/npp.2015.289. Epub 2015 Sep 11.


Endogenous opioids: opposing stress with a cost.

Valentino RJ, Van Bockstaele E.

F1000Prime Rep. 2015 May 12;7:58. doi: 10.12703/P7-58. eCollection 2015. Review.


Bilateral single-site intracerebral injection of a nonpathogenic herpes simplex virus-1 vector decreases anxiogenic behavior in MPS VII mice.

Liu W, Griffin G, Clarke T, Parente MK, Valentino RJ, Wolfe JH, Fraser NW.

Mol Ther Methods Clin Dev. 2015 Jan 28;2:14059. doi: 10.1038/mtm.2014.59. eCollection 2015.


Putting the past behind us: Social stress-induced urinary retention can be overcome.

Weiss DA, Butler SJ, Fesi J, Long CJ, Valentino RJ, Canning DA, Zderic SA.

J Pediatr Urol. 2015 Aug;11(4):188-94. doi: 10.1016/j.jpurol.2015.04.018. Epub 2015 May 27.


Corticotropin-releasing Factor in the Rat Dorsal Raphe Nucleus Promotes Different Forms of Behavioral Flexibility Depending on Social Stress History.

Snyder KP, Hill-Smith TE, Lucki I, Valentino RJ.

Neuropsychopharmacology. 2015 Oct;40(11):2517-25. doi: 10.1038/npp.2015.98. Epub 2015 Apr 13.


The impact of social stress during adolescence or adulthood and coping strategy on cognitive function of female rats.

Snyder K, Barry M, Plona Z, Ho A, Zhang XY, Valentino RJ.

Behav Brain Res. 2015 Jun 1;286:175-83. doi: 10.1016/j.bbr.2015.02.047. Epub 2015 Mar 5.


Inflammatory Factors Mediate Vulnerability to a Social Stress-Induced Depressive-like Phenotype in Passive Coping Rats.

Wood SK, Wood CS, Lombard CM, Lee CS, Zhang XY, Finnell JE, Valentino RJ.

Biol Psychiatry. 2015 Jul 1;78(1):38-48. doi: 10.1016/j.biopsych.2014.10.026. Epub 2014 Nov 25.


Endogenous Opioids: The Downside of Opposing Stress.

Valentino RJ, Van Bockstaele E.

Neurobiol Stress. 2015 Jan 1;1:23-32.


Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice.

Hwa LS, Shimamoto A, Kayyali T, Norman KJ, Valentino RJ, DeBold JF, Miczek KA.

Addict Biol. 2016 Jan;21(1):111-24. doi: 10.1111/adb.12189. Epub 2014 Sep 28.


Repeated social stress increases reward salience and impairs encoding of prediction by rat locus coeruleus neurons.

Chaijale NN, Snyder K, Arner J, Curtis AL, Valentino RJ.

Neuropsychopharmacology. 2015 Jan;40(2):513-23. doi: 10.1038/npp.2014.200. Epub 2014 Aug 11.


Using high resolution imaging to determine trafficking of corticotropin-releasing factor receptors in noradrenergic neurons of the rat locus coeruleus.

Reyes BA, Bangasser DA, Valentino RJ, Van Bockstaele EJ.

Life Sci. 2014 Sep 1;112(1-2):2-9. doi: 10.1016/j.lfs.2014.07.017. Epub 2014 Jul 21. Review.


Cognitive impact of social stress and coping strategy throughout development.

Snyder KP, Barry M, Valentino RJ.

Psychopharmacology (Berl). 2015 Jan;232(1):185-95. doi: 10.1007/s00213-014-3654-7. Epub 2014 Jun 24.


Sex differences in stress-related psychiatric disorders: neurobiological perspectives.

Bangasser DA, Valentino RJ.

Front Neuroendocrinol. 2014 Aug;35(3):303-19. doi: 10.1016/j.yfrne.2014.03.008. Epub 2014 Apr 12. Review.


Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice.

Toth M, Gresack JE, Bangasser DA, Plona Z, Valentino RJ, Flandreau EI, Mansuy IM, Merlo-Pich E, Geyer MA, Risbrough VB.

Neuropsychopharmacology. 2014 May;39(6):1409-19. doi: 10.1038/npp.2013.336. Epub 2013 Dec 11.


Neuropeptide regulation of the locus coeruleus and opiate-induced plasticity of stress responses.

Van Bockstaele EJ, Valentino RJ.

Adv Pharmacol. 2013;68:405-20. doi: 10.1016/B978-0-12-411512-5.00019-1. Review.


Sex-specific cell signaling: the corticotropin-releasing factor receptor model.

Valentino RJ, Van Bockstaele E, Bangasser D.

Trends Pharmacol Sci. 2013 Aug;34(8):437-44. doi: 10.1016/ Epub 2013 Jul 11. Review.


Social stress engages opioid regulation of locus coeruleus norepinephrine neurons and induces a state of cellular and physical opiate dependence.

Chaijale NN, Curtis AL, Wood SK, Zhang XY, Bhatnagar S, Reyes BA, Van Bockstaele EJ, Valentino RJ.

Neuropsychopharmacology. 2013 Sep;38(10):1833-43. doi: 10.1038/npp.2013.117. Epub 2013 May 10.


Manganese-enhanced magnetic resonance imaging (MEMRI) reveals brain circuitry involved in responding to an acute novel stress in rats with a history of repeated social stress.

Bangasser DA, Lee CS, Cook PA, Gee JC, Bhatnagar S, Valentino RJ.

Physiol Behav. 2013 Oct 2;122:228-36. doi: 10.1016/j.physbeh.2013.04.008. Epub 2013 May 2.


A corticotropin-releasing factor receptor antagonist improves urodynamic dysfunction produced by social stress or partial bladder outlet obstruction in male rats.

Wood SK, McFadden K, Griffin T, Wolfe JH, Zderic S, Valentino RJ.

Am J Physiol Regul Integr Comp Physiol. 2013 Jun 1;304(11):R940-50. doi: 10.1152/ajpregu.00257.2012. Epub 2013 Apr 3.


Cellular adaptations of dorsal raphe serotonin neurons associated with the development of active coping in response to social stress.

Wood SK, Zhang XY, Reyes BA, Lee CS, Van Bockstaele EJ, Valentino RJ.

Biol Psychiatry. 2013 Jun 1;73(11):1087-94. doi: 10.1016/j.biopsych.2013.01.026. Epub 2013 Feb 26.


Altered locus coeruleus-norepinephrine function following single prolonged stress.

George SA, Knox D, Curtis AL, Aldridge JW, Valentino RJ, Liberzon I.

Eur J Neurosci. 2013 Mar;37(6):901-9. doi: 10.1111/ejn.12095. Epub 2012 Dec 20.


Sex-biased stress signaling: the corticotropin-releasing factor receptor as a model.

Valentino RJ, Bangasser D, Van Bockstaele EJ.

Mol Pharmacol. 2013 Apr;83(4):737-45. doi: 10.1124/mol.112.083550. Epub 2012 Dec 13. Review.


Overexpression of corticotropin-releasing factor in Barrington's nucleus neurons by adeno-associated viral transduction: effects on bladder function and behavior.

McFadden K, Griffin TA, Levy V, Wolfe JH, Valentino RJ.

Eur J Neurosci. 2012 Nov;36(10):3356-64. doi: 10.1111/j.1460-9568.2012.08250.x. Epub 2012 Aug 8.


Increased vulnerability of the brain norepinephrine system of females to corticotropin-releasing factor overexpression.

Bangasser DA, Reyes BA, Piel D, Garachh V, Zhang XY, Plona ZM, Van Bockstaele EJ, Beck SG, Valentino RJ.

Mol Psychiatry. 2013 Feb;18(2):166-73. doi: 10.1038/mp.2012.24. Epub 2012 Apr 17.


Sex differences in molecular and cellular substrates of stress.

Bangasser DA, Valentino RJ.

Cell Mol Neurobiol. 2012 Jul;32(5):709-23. doi: 10.1007/s10571-012-9824-4. Epub 2012 Apr 10. Review.


Depressive and cardiovascular disease comorbidity in a rat model of social stress: a putative role for corticotropin-releasing factor.

Wood SK, McFadden KV, Grigoriadis D, Bhatnagar S, Valentino RJ.

Psychopharmacology (Berl). 2012 Jul;222(2):325-36. doi: 10.1007/s00213-012-2648-6. Epub 2012 Feb 10.


Predator stress engages corticotropin-releasing factor and opioid systems to alter the operating mode of locus coeruleus norepinephrine neurons.

Curtis AL, Leiser SC, Snyder K, Valentino RJ.

Neuropharmacology. 2012 Mar;62(4):1737-45. doi: 10.1016/j.neuropharm.2011.11.020. Epub 2011 Dec 23.


Corticotropin-releasing factor in the norepinephrine nucleus, locus coeruleus, facilitates behavioral flexibility.

Snyder K, Wang WW, Han R, McFadden K, Valentino RJ.

Neuropsychopharmacology. 2012 Jan;37(2):520-30. doi: 10.1038/npp.2011.218. Epub 2011 Oct 12.


Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy.

Carroll JC, Iba M, Bangasser DA, Valentino RJ, James MJ, Brunden KR, Lee VM, Trojanowski JQ.

J Neurosci. 2011 Oct 5;31(40):14436-49. doi: 10.1523/JNEUROSCI.3836-11.2011.


Molecular and cellular sex differences at the intersection of stress and arousal.

Valentino RJ, Reyes B, Van Bockstaele E, Bangasser D.

Neuropharmacology. 2012 Jan;62(1):13-20. doi: 10.1016/j.neuropharm.2011.06.004. Epub 2011 Jun 21. Review.


Collateralized dorsal raphe nucleus projections: a mechanism for the integration of diverse functions during stress.

Waselus M, Valentino RJ, Van Bockstaele EJ.

J Chem Neuroanat. 2011 Jul;41(4):266-80. doi: 10.1016/j.jchemneu.2011.05.011. Epub 2011 May 30. Review.


Sexual dimorphism in locus coeruleus dendritic morphology: a structural basis for sex differences in emotional arousal.

Bangasser DA, Zhang X, Garachh V, Hanhauser E, Valentino RJ.

Physiol Behav. 2011 Jun 1;103(3-4):342-51. doi: 10.1016/j.physbeh.2011.02.037. Epub 2011 Mar 6.


The bladder-brain connection: putative role of corticotropin-releasing factor.

Valentino RJ, Wood SK, Wein AJ, Zderic SA.

Nat Rev Urol. 2011 Jan;8(1):19-28. doi: 10.1038/nrurol.2010.203. Epub 2010 Dec 7. Review.

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