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The structural bases for agonist diversity in an Arabidopsis thaliana glutamate receptor-like channel.

Alfieri A, Doccula FG, Pederzoli R, Grenzi M, Bonza MC, Luoni L, Candeo A, Romano Armada N, Barbiroli A, Valentini G, Schneider TR, Bassi A, Bolognesi M, Nardini M, Costa A.

Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):752-760. doi: 10.1073/pnas.1905142117. Epub 2019 Dec 23.


Subclinical Pancreatitis as Onset of Systemic Lupus Erythematosus: Case Report and Review of the Literature.

Fasano S, Coscia MA, Valentini G.

J Clin Rheumatol. 2019 Aug 21. doi: 10.1097/RHU.0000000000001133. [Epub ahead of print] No abstract available.


Spatially modulated illumination allows for light sheet fluorescence microscopy with an incoherent source and compressive sensing.

Calisesi G, Castriotta M, Candeo A, Pistocchi A, D'Andrea C, Valentini G, Farina A, Bassi A.

Biomed Opt Express. 2019 Oct 17;10(11):5776-5788. doi: 10.1364/BOE.10.005776. eCollection 2019 Nov 1.


NEMO score in nailfold videocapillaroscopy is a good tool to assess both steady state levels and overtime changes of disease activity in patients with systemic sclerosis: a comparison with the proposed composite indices for this disease status entity.

Pignataro F, Maglione W, Minniti A, Sambataro D, Sambataro G, Campanaro F, Valentini G, Vitali C, Del Papa N.

Arthritis Res Ther. 2019 Nov 29;21(1):258. doi: 10.1186/s13075-019-2032-6.


The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.

Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkıran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidović RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijević V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton JB, Larsen DJ, Omdahl AR, McGuffin LJ, Brackenridge DA, Babbitt PC, Yunes JM, Fontana P, Zhang F, Zhu S, You R, Zhang Z, Dai S, Yao S, Tian W, Cao R, Chandler C, Amezola M, Johnson D, Chang JM, Liao WH, Liu YW, Pascarelli S, Frank Y, Hoehndorf R, Kulmanov M, Boudellioua I, Politano G, Di Carlo S, Benso A, Hakala K, Ginter F, Mehryary F, Kaewphan S, Björne J, Moen H, Tolvanen MEE, Salakoski T, Kihara D, Jain A, Šmuc T, Altenhoff A, Ben-Hur A, Rost B, Brenner SE, Orengo CA, Jeffery CJ, Bosco G, Hogan DA, Martin MJ, O'Donovan C, Mooney SD, Greene CS, Radivojac P, Friedberg I.

Genome Biol. 2019 Nov 19;20(1):244. doi: 10.1186/s13059-019-1835-8.


The association between duration of remission, fatigue, depression and health-related quality of life in Italian patients with systemic lupus erythematosus.

Margiotta DPE, Fasano S, Basta F, Pierro L, Riccardi A, Navarini L, Valentini G, Afeltra A.

Lupus. 2019 Dec;28(14):1705-1711. doi: 10.1177/0961203319884651. Epub 2019 Nov 10.


Novel time-resolved camera based on compressed sensing.

Farina A, Candeo A, Dalla Mora A, Bassi A, Lussana R, Villa F, Valentini G, Arridge S, D'Andrea C.

Opt Express. 2019 Oct 28;27(22):31889-31899. doi: 10.1364/OE.27.031889.


Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study.

Jaeger VK, Tikly M, Xu D, Siegert E, Hachulla E, Airò P, Valentini G, Matucci Cerinic M, Distler O, Cozzi F, Carreira P, Allanore Y, Müller-Ladner U, Ananieva LP, Balbir-Gurman A, Distler JHW, Czirják L, Li M, Henes J, Jimenez SA, Smith V, Damjanov N, Denton CP, DelGaldo F, Saketkoo LA, Walker UA; EUSTAR co-authors .

Rheumatology (Oxford). 2019 Nov 4. pii: kez486. doi: 10.1093/rheumatology/kez486. [Epub ahead of print]


Evaluation of the influence of social, demographic, environmental, work-related factors and/or lifestyle habits on Raynaud's phenomenon: a case-control study.

Prete M, Favoino E, Giacomelli R, Afeltra A, Cantatore FP, Bruno C, Corrado A, Emmi L, Emmi G, Grembiale RD, Navarini L, Marcoccia A, Liakouli V, Riccardi A, Valentini G, Perosa F; GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale).

Clin Exp Med. 2019 Nov 2. doi: 10.1007/s10238-019-00589-0. [Epub ahead of print]


Supersaturating drug delivery system of fixed drug combination: sulfamethoxazole and trimethoprim.

Mendes C, Valentini G, Chamorro Rengifo AF, Pinto JMO, Silva MAS, Parize AL.

Expert Rev Anti Infect Ther. 2019 Oct;17(10):841-850. doi: 10.1080/14787210.2019.1675508. Epub 2019 Oct 10.


Inflammation and Dysmetabolism in Systemic Autoimmune Diseases.

Afeltra A, Abbate A, Valentini G, Giacomelli R.

J Immunol Res. 2019 Jul 22;2019:5438287. doi: 10.1155/2019/5438287. eCollection 2019. No abstract available.


Revised European Scleroderma Trials and Research Group Activity Index is the best predictor of short-term severity accrual.

Fasano S, Riccardi A, Messiniti V, Caramaschi P, Rosato E, Maurer B, Smith V, Siegert E, De Langhe E, Riccieri V, Airó P, Mihai C, Avouac J, Zanatta E, Walker UA, Iannone F, García De la Peña Lefebvre P, Distler JHW, Vacca A, Distler O, Kowal-Bielecka O, Allanore Y, Valentini G.

Ann Rheum Dis. 2019 Dec;78(12):1681-1685. doi: 10.1136/annrheumdis-2019-215787. Epub 2019 Aug 17.


UNIPred-Web: a web tool for the integration and visualization of biomolecular networks for protein function prediction.

Perlasca P, Frasca M, Ba CT, Notaro M, Petrini A, Casiraghi E, Grossi G, Gliozzo J, Valentini G, Mesiti M.

BMC Bioinformatics. 2019 Aug 14;20(1):422. doi: 10.1186/s12859-019-2959-2.


Vasodilators and low-dose acetylsalicylic acid are associated with a lower incidence of distinct primary myocardial disease manifestations in systemic sclerosis: results of the DeSScipher inception cohort study.

Valentini G, Huscher D, Riccardi A, Fasano S, Irace R, Messiniti V, Matucci-Cerinic M, Guiducci S, Distler O, Maurer B, Avouac J, Tarner IH, Frerix M, Riemekasten G, Siegert E, Czirják L, Lóránd V, Denton CP, Nihtyanova S, Walker UA, Jaeger VK, Del Galdo F, Abignano G, Ananieva LP, Gherghe AM, Mihai C, Henes JC, Schmeiser T, Vacca A, Moiseev S, Foeldvari I, Gabrielli A, Krummel-Lorenz B, Rednic S, Allanore Y, Müeller-Ladner U.

Ann Rheum Dis. 2019 Nov;78(11):1576-1582. doi: 10.1136/annrheumdis-2019-215486. Epub 2019 Aug 7.


Undifferentiated connective tissue disease at risk of systemic sclerosis: A weighted score to identify patients who will evolve.

Riccardi A, Marcoccia A, Borgia A, Guastafierro T, Bondanini F, Fasano S, Irace R, Messiniti V, Sanduzzi A, Bocchino M, Ciani A, D'Alto M, Argiento P, De Matteis GM, Spanò A, Valentini G.

Autoimmun Rev. 2019 Sep;18(9):102358. doi: 10.1016/j.autrev.2019.102358. Epub 2019 Jul 16. No abstract available.


Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study.

Iacono D, Fasano S, Pantano I, D'Abrosca V, Ruscitti P, Margiotta DPE, Navarini L, Maruotti N, Grembiale RD, Cantatore FP, Afeltra A, Giacomelli R, Valentini G.

Cardiol Res Pract. 2019 May 2;2019:2748035. doi: 10.1155/2019/2748035. eCollection 2019.


Human osteogenic differentiation in Space: proteomic and epigenetic clues to better understand osteoporosis.

Gambacurta A, Merlini G, Ruggiero C, Diedenhofen G, Battista N, Bari M, Balsamo M, Piccirillo S, Valentini G, Mascetti G, Maccarrone M.

Sci Rep. 2019 Jun 6;9(1):8343. doi: 10.1038/s41598-019-44593-6.


Hyperspectral imaging with a TWINS birefringent interferometer.

Perri A, Nogueira de Faria BE, Ferreira DCT, Comelli D, Valentini G, Preda F, Polli D, de Paula AM, Cerullo G, Manzoni C.

Opt Express. 2019 May 27;27(11):15956-15967. doi: 10.1364/OE.27.015956.


Clinical features of patients with systemic lupus erythematosus according to health-related quality of life, entity of pain, fatigue and depression: a cluster analysis.

Margiotta DPE, Fasano S, Basta F, Pierro L, Riccardi A, Navarini L, Valentini G, Afeltra A.

Clin Exp Rheumatol. 2019 Jul-Aug;37(4):535-539. Epub 2019 May 29.


Hydroxychloroquine significantly reduces serum markers of endothelial injury and NEMO videocapillaroscopy score in systemic sclerosis.

Basta F, Irace R, Borgia A, Messiniti V, Riccardi A, Valentini G, Afeltra A.

Rheumatology (Oxford). 2019 Jul 1;58(7):1303-1305. doi: 10.1093/rheumatology/kez069. No abstract available.


Fluorescence lifetime imaging of intracellular magnesium content in live cells.

Sargenti A, Candeo A, Farruggia G, D'Andrea C, Cappadone C, Malucelli E, Valentini G, Taroni P, Iotti S.

Analyst. 2019 Mar 21;144(6):1876-1880. doi: 10.1039/c8an02379d. Epub 2019 Feb 27.


Degradation of Cadmium Yellow Paint: New Evidence from Photoluminescence Studies of Trap States in Picasso's Femme ( Époque des "Demoiselles d'Avignon").

Comelli D, MacLennan D, Ghirardello M, Phenix A, Schmidt Patterson C, Khanjian H, Gross M, Valentini G, Trentelman K, Nevin A.

Anal Chem. 2019 Mar 5;91(5):3421-3428. doi: 10.1021/acs.analchem.8b04914. Epub 2019 Feb 15.


Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation.

Funck-Brentano C, Bacchieri A, Valentini G, Pace S, Tommasini S, Voiriot P, Ubben D, Duparc S, Evene E, Felices M, Corsi M.

Sci Rep. 2019 Jan 28;9(1):777. doi: 10.1038/s41598-018-37112-6.


In Vivo Light Sheet Fluorescence Microscopy of Calcium Oscillations in Arabidopsis thaliana.

Romano Armada N, Doccula FG, Candeo A, Valentini G, Costa A, Bassi A.

Methods Mol Biol. 2019;1925:87-101. doi: 10.1007/978-1-4939-9018-4_8.


Anti-carbamylated protein antibodies and skin involvement in patients with systemic sclerosis: An intriguing association.

Favoino E, Prete M, Vettori S, Corrado A, Cantatore FP, Valentini G, Perosa F.

PLoS One. 2018 Dec 31;13(12):e0210023. doi: 10.1371/journal.pone.0210023. eCollection 2018.


Hemodynamic changes after acute fluid loading in patients with systemic sclerosis without pulmonary hypertension.

D'Alto M, Romeo E, Argiento P, Mattera Iacono A, Vettori S, Riccardi A, Allanore Y, D'Andrea A, Rea G, Bossone E, Valentini G, Naeije R, Golino P.

Pulm Circ. 2019 Jan-Mar;9(1):2045894018816089. doi: 10.1177/2045894018816089. Epub 2018 Nov 13.


A GPU-based algorithm for fast node label learning in large and unbalanced biomolecular networks.

Frasca M, Grossi G, Gliozzo J, Mesiti M, Notaro M, Perlasca P, Petrini A, Valentini G.

BMC Bioinformatics. 2018 Oct 15;19(Suppl 10):353. doi: 10.1186/s12859-018-2301-4.


Copper-64: a real theranostic agent.

Gutfilen B, Souza SA, Valentini G.

Drug Des Devel Ther. 2018 Oct 2;12:3235-3245. doi: 10.2147/DDDT.S170879. eCollection 2018. Review.


Low mortality rate in Italian rheumatoid arthritis patients from a tertiary center: putative implication of a low anti-carbamylated protein antibodies prevalence.

Iacono D, Favoino E, Borgia A, Fasano S, Pantano I, D'Abrosca V, Picillo G, Grembiale RD, Perosa F, Valentini G.

Open Access Rheumatol. 2018 Sep 6;10:129-134. doi: 10.2147/OARRR.S163731. eCollection 2018.


Prolonged remission is associated with a reduced risk of cardiovascular disease in patients with systemic lupus erythematosus: a GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study.

Fasano S, Margiotta DPE, Pierro L, Navarini L, Riccardi A, Afeltra A, Valentini G.

Clin Rheumatol. 2019 Feb;38(2):457-463. doi: 10.1007/s10067-018-4286-9. Epub 2018 Sep 7.


Time-Resolved Photoluminescence Microscopy Combined with X-ray Analyses and Raman Spectroscopy Sheds Light on the Imperfect Synthesis of Historical Cadmium Pigments.

Ghirardello M, Mosca S, Marti-Rujas J, Nardo L, Burnstock A, Nevin A, Bondani M, Toniolo L, Valentini G, Comelli D.

Anal Chem. 2018 Sep 18;90(18):10771-10779. doi: 10.1021/acs.analchem.8b01666. Epub 2018 Aug 30.


A water-filled garment to protect astronauts during interplanetary missions tested on board the ISS.

Baiocco G, Giraudo M, Bocchini L, Barbieri S, Locantore I, Brussolo E, Giacosa D, Meucci L, Steffenino S, Ballario A, Barresi B, Barresi R, Benassai M, Ravagnolo L, Narici L, Rizzo A, Carrubba E, Carubia F, Neri G, Crisconio M, Piccirillo S, Valentini G, Barbero S, Giacci M, Lobascio C, Ottolenghi A.

Life Sci Space Res (Amst). 2018 Aug;18:1-11. doi: 10.1016/j.lssr.2018.04.002. Epub 2018 Apr 26.


Post-veraison trimming slow down sugar accumulation without modifying phenolic ripening in Sangiovese vines.

Valentini G, Allegro G, Pastore C, Colucci E, Filippetti I.

J Sci Food Agric. 2019 Feb;99(3):1358-1365. doi: 10.1002/jsfa.9311. Epub 2018 Oct 8.


The non-additive effects of body size on nest architecture in a polymorphic ant.

Kwapich CL, Valentini G, Hölldobler B.

Philos Trans R Soc Lond B Biol Sci. 2018 Aug 19;373(1753). pii: 20170235. doi: 10.1098/rstb.2017.0235.


Brief Report: Smoking in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study.

Jaeger VK, Valentini G, Hachulla E, Cozzi F, Distler O, Airó P, Czirják L, Allanore Y, Siegert E, Rosato E, Matucci-Cerinic M, Caimmi C, Henes J, Carreira PE, Smith V, Del Galdo F, Denton CP, Ullman S, De Langhe E, Riccieri V, Alegre-Sancho JJ, Rednic S, Müller-Ladner U, Walker UA; EUSTAR coauthors.

Arthritis Rheumatol. 2018 Nov;70(11):1829-1834. doi: 10.1002/art.40557. Epub 2018 Sep 24.


Time-resolved multispectral imaging based on an adaptive single-pixel camera.

Rousset F, Ducros N, Peyrin F, Valentini G, D'Andrea C, Farina A.

Opt Express. 2018 Apr 16;26(8):10550-10558. doi: 10.1364/OE.26.010550.


Time domain diffuse Raman spectrometer based on a TCSPC camera for the depth analysis of diffusive media.

Konugolu Venkata Sekar S, Mosca S, Tannert S, Valentini G, Martelli F, Binzoni T, Prokazov Y, Turbin E, Zuschratter W, Erdmann R, Pifferi A.

Opt Lett. 2018 May 1;43(9):2134-2137. doi: 10.1364/OL.43.002134.


Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood.

Charlier B, Pingeon M, Dal Piaz F, Conti V, Valentini G, Filippelli A, Izzo V.

Biomed Chromatogr. 2018 Aug;32(8):e4258. doi: 10.1002/bmc.4258. Epub 2018 May 16.


Macrophage Activation Syndrome in Patients Affected by Adult-onset Still Disease: Analysis of Survival Rates and Predictive Factors in the Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale Cohort.

Ruscitti P, Iacono D, Ciccia F, Emmi G, Cipriani P, Grembiale RD, Perosa F, Emmi L, Triolo G, Giacomelli R, Valentini G.

J Rheumatol. 2018 Jun;45(6):864-872. doi: 10.3899/jrheum.170955. Epub 2018 Apr 15.


The incidence of cardiovascular events in Italian patients with systemic lupus erythematosus is lower than in North European and American cohorts: implication of disease-associated and traditional risk factors as emerged by a 16-year retrospective GIRRCS study: GIRRCS=Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale.

Fasano S, Margiotta DP, Gualtierotti R, Corrado A, Berardicurti O, Iacono D, Pierro L, Riccardi A, Giacomelli R, Cantatore FP, Meroni PL, Afeltra A, Valentini G.

Medicine (Baltimore). 2018 Apr;97(15):e0370. doi: 10.1097/MD.0000000000010370.


Esophageal high-resolution impedance manometry alterations in asymptomatic patients with systemic sclerosis: prevalence, associations with disease features, and prognostic value.

Vettori S, Tolone S, Capocotta D, Chieffo R, Giacco V, Valentini G, Docimo L.

Clin Rheumatol. 2018 May;37(5):1239-1247. doi: 10.1007/s10067-018-4026-1. Epub 2018 Feb 13.


Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group.

Adler S, Huscher D, Siegert E, Allanore Y, Czirják L, DelGaldo F, Denton CP, Distler O, Frerix M, Matucci-Cerinic M, Mueller-Ladner U, Tarner IH, Valentini G, Walker UA, Villiger PM, Riemekasten G; EUSTAR co-workers on behalf of the DeSScipher project research group within the EUSTAR network.

Arthritis Res Ther. 2018 Jan 30;20(1):17. doi: 10.1186/s13075-018-1517-z.


Time-Resolved Photoluminescence Microscopy for the Analysis of Semiconductor-Based Paint Layers.

Comelli D, Artesani A, Nevin A, Mosca S, Gonzalez V, Eveno M, Valentini G.

Materials (Basel). 2017 Nov 21;10(11). pii: E1335. doi: 10.3390/ma10111335.


Mortality in Italian patients with rheumatoid arthritis: evidence for a low mortality rate from cancer and infections in patients followed up at a tertiary center.

Iacono D, Fasano S, D'Abrosca V, Pantano I, Valentini G.

Open Access Rheumatol. 2017 Nov 3;9:185-189. doi: 10.2147/OARRR.S148270. eCollection 2017.


Efficacy and Tolerability Outcomes of a Phase II, Randomized, Open-Label, Multicenter Study of a New Water-Dispersible Pediatric Formulation of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in African Infants.

Gargano N, Madrid L, Valentini G, D'Alessandro U, Halidou T, Sirima S, Tshefu A, Mtoro A, Gesase S; Eurartesim Dispersible Study Group, Bassat Q.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e00596-17. doi: 10.1128/AAC.00596-17. Print 2018 Jan.


Subclinical atherosclerosis and history of cardiovascular events in Italian patients with rheumatoid arthritis: Results from a cross-sectional, multicenter GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study.

Ruscitti P, Margiotta DPE, Macaluso F, Iacono D, D'Onofrio F, Emmi G, Atzeni F, Prete M, Perosa F, Sarzi-Puttini P, Emmi L, Cantatore FP, Triolo G, Afeltra A, Giacomelli R, Valentini G.

Medicine (Baltimore). 2017 Oct;96(42):e8180. doi: 10.1097/MD.0000000000008180.


Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods.

Notaro M, Schubach M, Robinson PN, Valentini G.

BMC Bioinformatics. 2017 Oct 12;18(1):449. doi: 10.1186/s12859-017-1854-y.


Cardiac involvement in undifferentiated connective tissue disease at risk for systemic sclerosis (otherwise referred to as very early-early systemic sclerosis): a TDI study.

D'Alto M, Riccardi A, Argiento P, Di Stefano I, Romeo E, Iacono AM, D'Andrea A, Fasano S, Sanduzzi A, Bocchino M, Docimo L, Tolone S, Russo MG, Valentini G.

Clin Exp Med. 2018 May;18(2):237-243. doi: 10.1007/s10238-017-0477-y. Epub 2017 Oct 9.


Primary prevention of cardiovascular disease in patients with systemic lupus erythematosus: case series and literature review.

Fasano S, Margiotta DP, Navarini L, Pierro L, Pantano I, Riccardi A, Afeltra A, Valentini G.

Lupus. 2017 Dec;26(14):1463-1472. doi: 10.1177/0961203317722847. Epub 2017 Aug 8. Review.


A Photoluminescence Study of the Changes Induced in the Zinc White Pigment by Formation of Zinc Complexes.

Artesani A, Gherardi F, Nevin A, Valentini G, Comelli D.

Materials (Basel). 2017 Mar 25;10(4). pii: E340. doi: 10.3390/ma10040340.

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