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Items: 1 to 50 of 186

1.

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.

Olafsson S, Stridh P, Bos SD, Ingason A, Euesden J, Sulem P, Thorleifsson G, Gustafsson O, Johannesson A, Geirsson AJ, Thorsson AV, Sigurgeirsson B, Ludviksson BR, Olafsson E, Kristjansdottir H, Jonasson JG, Olafsson JH, Orvar KB, Benediktsson R, Bjarnason R, Kristjansdottir S, Gislason T, Valdimarsson T, Mikaelsdottir E, Sigurdsson S, Jonsson S, Rafnar T, Aarsland D, Djurovic S, Fladby T, Knudsen GP, Celius EG, Myhr KM, Grondal G, Steinsson K, Valdimarsson H, Bjornsson S, Bjornsdottir US, Bjornsson ES, Nilsson B, Andreassen OA, Alfredsson L, Hillert J, Kockum IS, Masson G, Thorsteinsdottir U, Gudbjartsson DF, Stefansson H, Hjaltason H, Harbo HF, Olsson T, Jonsdottir I, Stefansson K.

NPJ Genom Med. 2017 Aug 8;2:24. doi: 10.1038/s41525-017-0027-2. eCollection 2017.

2.

Patient-reported Outcomes and Clinical Response in Patients with Moderate-to-severe Plaque Psoriasis Treated with Tonsillectomy: A Randomized Controlled Trial.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Sigurdsson MI, Petersen H, Gudjonsson JE, Johnston A, Valdimarsson H.

Acta Derm Venereol. 2017 Mar 10;97(3):340-345. doi: 10.2340/00015555-2562.

3.

HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Petersen H, Sigurdsson MI, Gudjonsson JE, Johnston A, Valdimarsson H.

J Am Acad Dermatol. 2016 Nov;75(5):889-896. doi: 10.1016/j.jaad.2016.06.061. Epub 2016 Aug 9.

4.

Throat Infections are Associated with Exacerbation in a Substantial Proportion of Patients with Chronic Plaque Psoriasis.

Thorleifsdottir RH, Eysteinsdóttir JH, Olafsson JH, Sigurdsson MI, Johnston A, Valdimarsson H, Sigurgeirsson B.

Acta Derm Venereol. 2016 Aug 23;96(6):788-91. doi: 10.2340/00015555-2408.

5.

The role of Th17/Tc17 peripheral blood T cells in psoriasis and their positive therapeutic response.

Eysteinsdóttir JH, Sigurgeirsson B, Ólafsson JH, Fridriksson T, Agnarsson BA, Davíðsson S, Valdimarsson H, Lúðvíksson BR.

Scand J Immunol. 2013 Dec;78(6):529-37. doi: 10.1111/sji.12114.

6.

The association of sore throat and psoriasis might be explained by histologically distinctive tonsils and increased expression of skin-homing molecules by tonsil T cells.

Sigurdardottir SL, Thorleifsdottir RH, Valdimarsson H, Johnston A.

Clin Exp Immunol. 2013 Oct;174(1):139-51. doi: 10.1111/cei.12153.

7.

Defective immunoglobulin A (IgA) glycosylation and IgA deposits in patients with IgA nephropathy.

Kolka R, Valdimarsson H, Bodvarsson M, Hardarson S, Jonsson T.

APMIS. 2013 Sep;121(9):890-7. doi: 10.1111/apm.12051. Epub 2013 Feb 11.

PMID:
23398317
8.

The role of the palatine tonsils in the pathogenesis and treatment of psoriasis.

Sigurdardottir SL, Thorleifsdottir RH, Valdimarsson H, Johnston A.

Br J Dermatol. 2013 Feb;168(2):237-42. doi: 10.1111/j.1365-2133.2012.11215.x. Epub 2012 Dec 13. Review.

9.

Psoriatic arthritis and onycholysis -- results from the cross-sectional Reykjavik psoriatic arthritis study.

Love TJ, Gudjonsson JE, Valdimarsson H, Gudbjornsson B.

J Rheumatol. 2012 Jul;39(7):1441-4. doi: 10.3899/jrheum.111298. Epub 2012 May 15.

PMID:
22589259
10.

Improvement of psoriasis after tonsillectomy is associated with a decrease in the frequency of circulating T cells that recognize streptococcal determinants and homologous skin determinants.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Sigurdsson MI, Petersen H, Arnadottir S, Gudjonsson JE, Johnston A, Valdimarsson H.

J Immunol. 2012 May 15;188(10):5160-5. doi: 10.4049/jimmunol.1102834. Epub 2012 Apr 9.

11.

A long-term follow-up of allergic diseases in Iceland.

Finnbogadóttir AF, Árdal B, Eiríksson H, Hrafnkelsson B, Valdimarsson H, Lúðvíksson BR, Haraldsson Á.

Pediatr Allergy Immunol. 2012 Mar;23(2):181-5. doi: 10.1111/j.1399-3038.2011.01234.x. Epub 2012 Feb 2.

PMID:
22300372
12.

The anti-microbial peptide LL-37 modulates immune responses in the palatine tonsils where it is exclusively expressed by neutrophils and a subset of dendritic cells.

Sigurdardottir SL, Thorleifsdottir RH, Guzman AM, Gudmundsson GH, Valdimarsson H, Johnston A.

Clin Immunol. 2012 Feb;142(2):139-49. doi: 10.1016/j.clim.2011.09.013. Epub 2011 Oct 7.

PMID:
22036268
13.

Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers.

Saevarsdottir S, Ding B, Steinsson K, Grondal G, Valdimarsson H, Alfredsson L, Klareskog L, Padyukov L.

Arthritis Res Ther. 2011 Apr 15;13(2):R65. doi: 10.1186/ar3321.

14.

Seasonal changes in migratory and predatory activity of two species of gadoid preying on inshore northern shrimp Pandalus borealis.

Björnsson B, Reynisson P, Solmundsson J, Valdimarsson H.

J Fish Biol. 2011 Apr;78(4):1110-31. doi: 10.1111/j.1095-8649.2011.02923.x. Epub 2011 Mar 11.

PMID:
21463310
15.

Small joint involvement in psoriatic arthritis is associated with onycholysis: the Reykjavik Psoriatic Arthritis Study.

Love TJ, Gudjonsson JE, Valdimarsson H, Gudbjornsson B.

Scand J Rheumatol. 2010 Aug;39(4):299-302. doi: 10.3109/03009741003604559.

PMID:
20476857
16.

Psoriasis--as an autoimmune disease caused by molecular mimicry.

Valdimarsson H, Thorleifsdottir RH, Sigurdardottir SL, Gudjonsson JE, Johnston A.

Trends Immunol. 2009 Oct;30(10):494-501. doi: 10.1016/j.it.2009.07.008. Epub 2009 Sep 24. Review.

PMID:
19781993
17.

Effect of rheumatoid factor on mortality and coronary heart disease.

Tomasson G, Aspelund T, Jonsson T, Valdimarsson H, Felson DT, Gudnason V.

Ann Rheum Dis. 2010 Sep;69(9):1649-54. doi: 10.1136/ard.2009.110536. Epub 2009 Jul 23.

18.

Association of three systemic lupus erythematosus susceptibility factors, PD-1.3A, C4AQ0, and low levels of mannan-binding lectin, with autoimmune manifestations in Icelandic multicase systemic lupus erythematosus families.

Kristjansdottir H, Saevarsdottir S, Gröndal G, Alarcón-Riquelme ME, Erlendsson K, Valdimarsson H, Steinsson K.

Arthritis Rheum. 2008 Dec;58(12):3865-72. doi: 10.1002/art.24129.

19.

Do non-steroidal anti-inflammatory drugs influence chronic inflammation? The effects of piroxicam on chronic antigen-induced arthritis in rats.

Sigurdardottir SL, Freysdottir J, Vikingsdottir T, Valdimarsson H, Vikingsson A.

Scand J Rheumatol. 2008 Nov-Dec;37(6):469-76. doi: 10.1080/03009740802225876.

PMID:
19005999
20.

Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection.

Eisen DP, Dean MM, Boermeester MA, Fidler KJ, Gordon AC, Kronborg G, Kun JF, Lau YL, Payeras A, Valdimarsson H, Brett SJ, Ip WK, Mila J, Peters MJ, Saevarsdottir S, van Till JW, Hinds CJ, McBryde ES.

Clin Infect Dis. 2008 Aug 15;47(4):510-6. doi: 10.1086/590006.

PMID:
18611155
21.

Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation.

Johnston A, Arnadottir S, Gudjonsson JE, Aphale A, Sigmarsdottir AA, Gunnarsson SI, Steinsson JT, Elder JT, Valdimarsson H.

Br J Dermatol. 2008 Aug;159(2):342-50. doi: 10.1111/j.1365-2133.2008.08655.x. Epub 2008 Jun 28.

22.

The genetic basis of psoriasis.

Valdimarsson H.

Clin Dermatol. 2007 Nov-Dec;25(6):563-7. Review.

PMID:
18021893
23.

The pharmacokinetic profile of plasma-derived mannan-binding lectin in healthy adult volunteers and patients with Staphylococcus aureus septicaemia.

Bang P, Laursen I, Thornberg K, Schierbeck J, Nielsen B, Valdimarsson H, Koch C, Christiansen M.

Scand J Infect Dis. 2008;40(1):44-8. Epub 2007 Jul 27.

PMID:
17852940
24.

Psoriatic arthritis in Reykjavik, Iceland: prevalence, demographics, and disease course.

Love TJ, Gudbjornsson B, Gudjonsson JE, Valdimarsson H.

J Rheumatol. 2007 Oct;34(10):2082-8. Epub 2007 Aug 1.

PMID:
17696270
25.

Patients with rheumatoid arthritis have higher levels of mannan-binding lectin than their first-degree relatives and unrelated controls.

Saevarsdottir S, Steinsson K, Grondal G, Valdimarsson H.

J Rheumatol. 2007 Aug;34(8):1692-5. Epub 2007 Jun 15.

PMID:
17610322
26.

Mouse models of psoriasis.

Gudjonsson JE, Johnston A, Dyson M, Valdimarsson H, Elder JT.

J Invest Dermatol. 2007 Jun;127(6):1292-308. Epub 2007 Apr 12. Review.

27.

Mannan-binding lectin may facilitate the clearance of circulating immune complexes--implications from a study on C2-deficient individuals.

Saevarsdottir S, Steinsson K, Ludviksson BR, Grondal G, Valdimarsson H.

Clin Exp Immunol. 2007 May;148(2):248-53. Epub 2007 Mar 5.

28.

[Allergy and asthma in Icelandic children - an epidemiological study.].

Eiríksson H, Ardal B, Lúðvíksson BR, Sigfússon A, Valdimarsson H, Haraldsson A.

Laeknabladid. 2000 Feb;86(2):102-7. Icelandic.

PMID:
17018913
29.

[Alternative medicine [Editorial].].

Valdimarsson HB.

Laeknabladid. 2002 Mar;88(3):185-6. Icelandic. No abstract available.

PMID:
16940647
30.

Distinct clinical differences between HLA-Cw*0602 positive and negative psoriasis patients--an analysis of 1019 HLA-C- and HLA-B-typed patients.

Gudjonsson JE, Karason A, Runarsdottir EH, Antonsdottir AA, Hauksson VB, Jónsson HH, Gulcher J, Stefansson K, Valdimarsson H.

J Invest Dermatol. 2006 Apr;126(4):740-5.

31.

Mannan-binding lectin and complement C4A in Icelandic multicase families with systemic lupus erythematosus.

Saevarsdottir S, Kristjansdottir H, Grondal G, Vikingsdottir T, Steinsson K, Valdimarsson H.

Ann Rheum Dis. 2006 Nov;65(11):1462-7. Epub 2006 Jan 26.

32.

The effects of tobacco smoking and rheumatoid factor seropositivity on disease activity and joint damage in early rheumatoid arthritis.

Manfredsdottir VF, Vikingsdottir T, Jonsson T, Geirsson AJ, Kjartansson O, Heimisdottir M, Sigurdardottir SL, Valdimarsson H, Vikingsson A.

Rheumatology (Oxford). 2006 Jun;45(6):734-40. Epub 2006 Jan 10.

PMID:
16403829
33.

Influence of the Atlantic subpolar gyre on the thermohaline circulation.

Hátún H, Sandø AB, Drange H, Hansen B, Valdimarsson H.

Science. 2005 Sep 16;309(5742):1841-4.

34.

Genetics of psoriasis in Iceland: evidence for linkage of subphenotypes to distinct Loci.

Karason A, Gudjonsson JE, Jónsson HH, Hauksson VB, Runarsdottir EH, Stefansson K, Valdimarsson H, Gulcher JR.

J Invest Dermatol. 2005 Jun;124(6):1177-85.

35.

Narrowband-UVB irradiation decreases the production of pro-inflammatory cytokines by stimulated T cells.

Sigmundsdottir H, Johnston A, Gudjonsson JE, Valdimarsson H.

Arch Dermatol Res. 2005 Jul;297(1):39-42. Epub 2005 May 12.

PMID:
15889264
36.

Childhood levels of immunoglobulins and mannan-binding lectin in relation to infections and allergy.

Thórarinsdóttir HK, Lúdvíksson BR, Víkingsdóttir T, Leópoldsdóttir MO, Ardal B, Jónsson T, Valdimarsson H, Arason GJ.

Scand J Immunol. 2005 May;61(5):466-74.

37.

Allergic diseases and asthma in relation to serum immunoglobulins and salivary immunoglobulin A in pre-school children: a follow-up community-based study.

Lúdvíksson BR, Arason GJ, Thorarensen O, Ardal B, Valdimarsson H.

Clin Exp Allergy. 2005 Jan;35(1):64-9.

PMID:
15649268
38.

The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules.

Johnston A, Gudjonsson JE, Sigmundsdottir H, Ludviksson BR, Valdimarsson H.

Clin Immunol. 2005 Feb;114(2):154-63.

PMID:
15639649
39.

Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk.

Saevarsdottir S, Oskarsson OO, Aspelund T, Eiriksdottir G, Vikingsdottir T, Gudnason V, Valdimarsson H.

J Exp Med. 2005 Jan 3;201(1):117-25. Epub 2004 Dec 28.

40.
41.

Psoriasis: a complex clinical and genetic disorder.

Valdimarsson H, Karason A, Gudjonsson JE.

Curr Rheumatol Rep. 2004 Aug;6(4):314-6. Review.

PMID:
15251084
42.

The potential role of mannan-binding lectin in the clearance of self-components including immune complexes.

Saevarsdottir S, Vikingsdottir T, Valdimarsson H.

Scand J Immunol. 2004 Jul-Aug;60(1-2):23-9. Review.

43.

Methotrexate markedly reduces the expression of vascular E-selectin, cutaneous lymphocyte-associated antigen and the numbers of mononuclear leucocytes in psoriatic skin.

Sigmundsdottir H, Johnston A, Gudjonsson JE, Bjarnason B, Valdimarsson H.

Exp Dermatol. 2004 Jul;13(7):426-34.

PMID:
15217363
44.
45.

Patients with systemic lupus erythematosus are deficient in complement-dependent prevention of immune precipitation.

Arason GJ, Steinsson K, Kolka R, Víkingsdóttir T, D'Ambrogio MS, Valdimarsson H.

Rheumatology (Oxford). 2004 Jun;43(6):783-9. Epub 2004 Mar 30.

PMID:
15054157
46.

Human plasma-derived mannose-binding lectin: a phase I safety and pharmacokinetic study.

Valdimarsson H, Vikingsdottir T, Bang P, Saevarsdottir S, Gudjonsson JE, Oskarsson O, Christiansen M, Blou L, Laursen I, Koch C.

Scand J Immunol. 2004 Jan;59(1):97-102.

47.

Immunopathogenic mechanisms in psoriasis.

Gudjonsson JE, Johnston A, Sigmundsdottir H, Valdimarsson H.

Clin Exp Immunol. 2004 Jan;135(1):1-8. Review.

48.

Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study.

Gudjonsson JE, Thorarinsson AM, Sigurgeirsson B, Kristinsson KG, Valdimarsson H.

Br J Dermatol. 2003 Sep;149(3):530-4.

PMID:
14510985
49.

Infusion of plasma-derived mannan-binding lectin (MBL) into MBL-deficient humans.

Valdimarsson H.

Biochem Soc Trans. 2003 Aug;31(Pt 4):768-9.

PMID:
12887300
50.

The effects of ultraviolet B treatment on the expression of adhesion molecules by circulating T lymphocytes in psoriasis.

Sigmundsdottir H, Gudjonsson JE, Valdimarsson H.

Br J Dermatol. 2003 May;148(5):996-1000.

PMID:
12786832

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