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Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58⁻K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities.

Sikorra S, Skiba M, Dorner MB, Weisemann J, Weil M, Valdezate S, Davletov B, Rummel A, Dorner BG, Binz T.

Toxins (Basel). 2018 Aug 1;10(8). pii: E311. doi: 10.3390/toxins10080311.


First Insight into the Genome Sequences of Two Linezolid-Resistant Nocardia farcinica Strains Isolated from Patients with Cystic Fibrosis.

Valdezate S, Monzón S, Garrido N, Zaballos A, Medina-Pascual MJ, Azcona-Gutiérrez JM, Vilar B, Cuesta I.

Genome Announc. 2017 Nov 16;5(46). pii: e01212-17. doi: 10.1128/genomeA.01212-17.


First Draft Genome Sequence of a Clinical Strain of Nocardia cerradoensis.

Carrasco G, Monzón S, Jiménez P, Cuesta I, Bartolomé-Alvarez J, Valdezate S.

Genome Announc. 2017 Sep 28;5(39). pii: e00551-17. doi: 10.1128/genomeA.00551-17.


Paenibacillus spp. isolated from human and environmental samples in Spain: detection of 11 new species.

Sáez-Nieto JA, Medina-Pascual MJ, Carrasco G, Garrido N, Fernandez-Torres MA, Villalón P, Valdezate S.

New Microbes New Infect. 2017 May 24;19:19-27. doi: 10.1016/j.nmni.2017.05.006. eCollection 2017 Sep.


Epidemiology and susceptibility to antimicrobial agents of the main Nocardia species in Spain.

Valdezate S, Garrido N, Carrasco G, Medina-Pascual MJ, Villalón P, Navarro AM, Saéz-Nieto JA.

J Antimicrob Chemother. 2017 Mar 1;72(3):754-761. doi: 10.1093/jac/dkw489.


Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis.

Fernández-Natal I, Rodríguez-Lázaro D, Marrodán-Ciordia T, Sáez-Nieto JA, Valdezate S, Rodríguez-Pollán H, Tauch A, Soriano F.

New Microbes New Infect. 2016 Sep 10;14:93-97. eCollection 2016 Nov.


Shortcomings of the Commercial MALDI-TOF MS Database and Use of MLSA as an Arbiter in the Identification of Nocardia Species.

Carrasco G, de Dios Caballero J, Garrido N, Valdezate S, Cantón R, Sáez-Nieto JA.

Front Microbiol. 2016 Apr 21;7:542. doi: 10.3389/fmicb.2016.00542. eCollection 2016.


Traumatic endophthalmitis caused by Nocardia kruczakiae in a patient with traumatic eye injury.

Compte RB, Martínez-Osorio H, Carrasco G, Lorente B, Elizalde J, Valdezate S, Lorente R, Iglesias E, Saez-Nieto JA.

J Ophthalmic Inflamm Infect. 2015 Dec;5(1):36. doi: 10.1186/s12348-015-0067-7. Epub 2015 Nov 25.


Resistance gene pool to co-trimoxazole in non-susceptible Nocardia strains.

Valdezate S, Garrido N, Carrasco G, Villalón P, Medina-Pascual MJ, Saéz-Nieto JA.

Front Microbiol. 2015 Apr 28;6:376. doi: 10.3389/fmicb.2015.00376. eCollection 2015.


Endemic and epidemic Acinetobacter baumannii clones: a twelve-year study in a tertiary care hospital.

Villalón P, Valdezate S, Cabezas T, Ortega M, Garrido N, Vindel A, Medina-Pascual MJ, Saez-Nieto JA.

BMC Microbiol. 2015 Feb 25;15:47. doi: 10.1186/s12866-015-0383-y.


Increase in isolation of Burkholderia contaminans from Spanish patients with cystic fibrosis.

Medina-Pascual MJ, Valdezate S, Carrasco G, Villalón P, Garrido N, Saéz-Nieto JA.

Clin Microbiol Infect. 2015 Feb;21(2):150-6. doi: 10.1016/j.cmi.2014.07.014. Epub 2014 Oct 12.


gyrB analysis as a tool for identifying Nocardia species and exploring their phylogeny.

Carrasco G, Valdezate S, Garrido N, Medina-Pascual MJ, Villalón P, Sáez-Nieto JA.

J Clin Microbiol. 2015 Mar;53(3):997-1001. doi: 10.1128/JCM.03072-14. Epub 2014 Dec 24.


Dermabacter hominis: a usually daptomycin-resistant gram-positive organism infrequently isolated from human clinical samples.

Fernández-Natal I, Sáez-Nieto JA, Medina-Pascual MJ, Albersmeier A, Valdezate S, Guerra-Laso JM, Rodríguez H, Marrodán T, Parras T, Tauch A, Soriano F.

New Microbes New Infect. 2013 Dec;1(3):35-40. doi: 10.1002/2052-2975.31. Epub 2014 Jan 13.


Identification, typing, and phylogenetic relationships of the main clinical Nocardia species in spain according to their gyrB and rpoB genes.

Carrasco G, Valdezate S, Garrido N, Villalón P, Medina-Pascual MJ, Sáez-Nieto JA.

J Clin Microbiol. 2013 Nov;51(11):3602-8. doi: 10.1128/JCM.00515-13. Epub 2013 Aug 21.


Presence of the vanC1 gene in a vancomycin-resistant Enterococcus faecalis strain isolated from ewe bulk tank milk.

de Garnica ML, Valdezate S, Gonzalo C, Saez-Nieto JA.

J Med Microbiol. 2013 Mar;62(Pt 3):494-5. doi: 10.1099/jmm.0.052274-0. Epub 2012 Nov 15. No abstract available.


Two simultaneous botulism outbreaks in Barcelona: Clostridium baratii and Clostridium botulinum.

Lafuente S, Nolla J, Valdezate S, Tortajada C, Vargas-Leguas H, Parron I, Sáez-Nieto JA, Portaña S, Carrasco G, Moguel E, Sabate S, Argelich R, Caylà JA.

Epidemiol Infect. 2013 Sep;141(9):1993-5. doi: 10.1017/S0950268812002592. Epub 2012 Nov 19.


Epidemiology of the Acinetobacter-derived cephalosporinase, carbapenem-hydrolysing oxacillinase and metallo-β-lactamase genes, and of common insertion sequences, in epidemic clones of Acinetobacter baumannii from Spain.

Villalón P, Valdezate S, Medina-Pascual MJ, Carrasco G, Vindel A, Saez-Nieto JA.

J Antimicrob Chemother. 2013 Mar;68(3):550-3. doi: 10.1093/jac/dks448. Epub 2012 Nov 9.


Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006).

Rubio-López V, Valdezate S, Alvarez D, Villalón P, Medina MJ, Salcedo C, Sáez-Nieto JA.

BMC Microbiol. 2012 Sep 21;12:215. doi: 10.1186/1471-2180-12-215.


Meningitis caused by Abiotrophia defectiva: case report and literature review.

Tena D, Solís S, Lainez S, Torralba M, Chacón P, Valdezate S, Sáez-Nieto JA, Bisquert J.

Infection. 2013 Apr;41(2):571-4. doi: 10.1007/s15010-012-0318-6. Epub 2012 Aug 23. Review.


Identification, molecular characterisation and antimicrobial susceptibility of genomovars of the Burkholderia cepacia complex in Spain.

Medina-Pascual MJ, Valdezate S, Villalón P, Garrido N, Rubio V, Saéz-Nieto JA.

Eur J Clin Microbiol Infect Dis. 2012 Dec;31(12):3385-96. doi: 10.1007/s10096-012-1707-6. Epub 2012 Aug 2.


Clonal outbreak of ST17 multidrug-resistant Enterococcus faecium harbouring an Inc18-like::Tn1546 plasmid in a haemo-oncology ward of a Spanish hospital.

Valdezate S, Miranda C, Navarro A, Freitas AR, Cabrera JJ, Carrasco G, Coque TM, Jiménez-Romano E, Saéz-Nieto JA.

J Antimicrob Chemother. 2012 Apr;67(4):832-6. doi: 10.1093/jac/dkr545. Epub 2012 Jan 6.


[Bacterial identification methods in the microbiology laboratory].

Bou G, Fernández-Olmos A, García C, Sáez-Nieto JA, Valdezate S.

Enferm Infecc Microbiol Clin. 2011 Oct;29(8):601-8. doi: 10.1016/j.eimc.2011.03.012. Epub 2011 Jun 17. Review. Spanish.


Clonal diversity of nosocomial epidemic Acinetobacter baumannii strains isolated in Spain.

Villalón P, Valdezate S, Medina-Pascual MJ, Rubio V, Vindel A, Saez-Nieto JA.

J Clin Microbiol. 2011 Mar;49(3):875-82. doi: 10.1128/JCM.01026-10. Epub 2010 Dec 22.


Study of the molecular mechanisms involved in high-level macrolide resistance of Spanish Campylobacter jejuni and Campylobacter coli strains.

Pérez-Boto D, López-Portolés JA, Simón C, Valdezate S, Echeita MA.

J Antimicrob Chemother. 2010 Oct;65(10):2083-8. doi: 10.1093/jac/dkq268. Epub 2010 Jul 20.


Epidemiological and phylogenetic analysis of Spanish human Brucella melitensis strains by multiple-locus variable-number tandem-repeat typing, hypervariable octameric oligonucleotide fingerprinting, and rpoB typing.

Valdezate S, Navarro A, Villalón P, Carrasco G, Saéz-Nieto JA.

J Clin Microbiol. 2010 Aug;48(8):2734-40. doi: 10.1128/JCM.00533-10. Epub 2010 Jun 16.


Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.

Turrientes MC, Baquero MR, Sánchez MB, Valdezate S, Escudero E, Berg G, Cantón R, Baquero F, Galán JC, Martínez JL.

Appl Environ Microbiol. 2010 Mar;76(6):1746-58. doi: 10.1128/AEM.02817-09. Epub 2010 Jan 22.


Molecular screening for rifampicin and fluoroquinolone resistance in a clinical population of Brucella melitensis.

Valdezate S, Navarro A, Medina-Pascual MJ, Carrasco G, Saéz-Nieto JA.

J Antimicrob Chemother. 2010 Jan;65(1):51-3. doi: 10.1093/jac/dkp389.


Emergence of a clonal lineage of Brucella abortus biovar 3 in clinical cases in Spain.

Valdezate S, Navarro A, Rubio V, Garin-Bastuji B, Albert D, Hernandez P, Alonso PM, Saéz-Nieto JA.

J Clin Microbiol. 2009 Aug;47(8):2687-8. doi: 10.1128/JCM.00756-09. Epub 2009 Jun 24. No abstract available.


Isolation of Corynebacterium ureicelerivorans from normally sterile sites in humans.

Fernández-Natal MI, Sáez-Nieto JA, Valdezate S, Rodríguez-Pollán RH, Lapeña S, Cachón F, Soriano F.

Eur J Clin Microbiol Infect Dis. 2009 Jun;28(6):677-81. doi: 10.1007/s10096-008-0677-1. Epub 2008 Dec 17.


Large clonal outbreak of multidrug-resistant CC17 ST17 Enterococcus faecium containing Tn5382 in a Spanish hospital.

Valdezate S, Labayru C, Navarro A, Mantecón MA, Ortega M, Coque TM, García M, Saéz-Nieto JA.

J Antimicrob Chemother. 2009 Jan;63(1):17-20. doi: 10.1093/jac/dkn449. Epub 2008 Nov 11.


Urinary tract infection caused by capnophilic Escherichia coli.

Tena D, González-Praetorius A, Sáez-Nieto JA, Valdezate S, Bisquert J.

Emerg Infect Dis. 2008 Jul;14(7):1163-4. doi: 10.3201/eid1407.071053. No abstract available.


Granulibacter bethesdensis isolated in a child patient with chronic granulomatous disease.

López FC, de Luna FF, Delgado MC, de la Rosa II, Valdezate S, Nieto JA, Casal M.

J Infect. 2008 Sep;57(3):275-7. doi: 10.1016/j.jinf.2008.04.011. Epub 2008 Jun 16.


Nosocomial Outbreaks Caused by Leuconostoc mesenteroides subsp. mesenteroides.

Bou G, Luis Saleta J, Sáez Nieto JA, Tomás M, Valdezate S, Sousa D, Lueiro F, Villanueva R, Jose Pereira M, Llinares P.

Emerg Infect Dis. 2008 Jun;14(6):968-71. doi: 10.3201/eid1406.071095.


Outbreak of Burkholderia cepacia bacteremia caused by contaminated chlorhexidine in a hemodialysis unit.

Romero-Gómez MP, Quiles-Melero MI, Peña García P, Gutiérrez Altes A, García de Miguel MA, Jiménez C, Valdezate S, Sáez Nieto JA.

Infect Control Hosp Epidemiol. 2008 Apr;29(4):377-8. doi: 10.1086/529032. No abstract available.


Antimicrobial resistance and phage and molecular typing of Salmonella strains isolated from food for human consumption in Spain.

Valdezate S, Arroyo M, González-Sanz R, Ramíro R, Herrera-León S, Usera MA, De la Fuente M, Echeita A.

J Food Prot. 2007 Dec;70(12):2741-8.


The isolation of Corynebacterium coyleae from clinical samples: clinical and microbiological data.

Fernández-Natal MI, Sáez-Nieto JA, Fernández-Roblas R, Asencio M, Valdezate S, Lapeña S, Rodríguez-Pollán RH, Guerra JM, Blanco J, Cachón F, Soriano F.

Eur J Clin Microbiol Infect Dis. 2008 Mar;27(3):177-84. Epub 2007 Nov 9.


Epidemiological tracing of Salmonella enterica serotype Abortusovis from Spanish ovine flocks by PFGE fingerprinting.

Valdezate S, Astorga R, Herrera-León S, Perea A, Usera MA, Huerta B, Echeita A.

Epidemiol Infect. 2007 May;135(4):695-702. Epub 2006 Aug 10.


Prevalence and evolution of methicillin-resistant Staphylococcus aureus in Spanish hospitals between 1996 and 2002.

Vindel A, Trincado P, Gómez E, Cabrera R, Boquete T, Solá C, Valdezate S, Saez-Nieto JA.

J Clin Microbiol. 2006 Jan;44(1):266-70.


Outbreak of long-term intravascular catheter-related bacteremia due to Achromobacter xylosoxidans subspecies xylosoxidans in a hemodialysis unit.

Tena D, Carranza R, Barberá JR, Valdezate S, Garrancho JM, Arranz M, Sáez-Nieto JA.

Eur J Clin Microbiol Infect Dis. 2005 Nov;24(11):727-32.


Preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic Stenotrophomonas maltophilia strains.

Valdezate S, Vindel A, Saéz-Nieto JA, Baquero F, Cantón R.

J Antimicrob Chemother. 2005 Jul;56(1):220-3. Epub 2005 May 31.


Salmonella Derby clonal spread from pork.

Valdezate S, Vidal A, Herrera-León S, Pozo J, Rubio P, Usera MA, Carvajal A, Echeita MA.

Emerg Infect Dis. 2005 May;11(5):694-8.


High genetic diversity among Stenotrophomonas maltophilia strains despite their originating at a single hospital.

Valdezate S, Vindel A, Martín-Dávila P, Del Saz BS, Baquero F, Cantón R.

J Clin Microbiol. 2004 Feb;42(2):693-9.


Antimicrobial susceptibility profile of molecular typed cystic fibrosis Stenotrophomonas maltophilia isolates and differences with noncystic fibrosis isolates.

Cantón R, Valdezate S, Vindel A, Sánchez Del Saz B, Maíz L, Baquero F.

Pediatr Pulmonol. 2003 Feb;35(2):99-107.


[Multiresistant pathogens in cystic fibrosis].

Cantón R, Girón R, Martínez-Martínez L, Oliver A, Solé A, Valdezate S, Máiz L.

Arch Bronconeumol. 2002 Aug;38(8):376-85. Review. Spanish. No abstract available.


[An update on the susceptibility of Stenotrophomonas maltophilia].

Sevillano D, Valdezate S, Gómez-Lus ML.

Rev Esp Quimioter. 2001 Jun;14(2):138-54. Review. Spanish. No abstract available.


Antimicrobial susceptibilities of unique Stenotrophomonas maltophilia clinical strains.

Valdezate S, Vindel A, Loza E, Baquero F, Cantón R.

Antimicrob Agents Chemother. 2001 May;45(5):1581-4.


Persistence and variability of Stenotrophomonas maltophilia in cystic fibrosis patients, Madrid, 1991-1998.

Valdezate S, Vindel A, Maiz L, Baquero F, Escobar H, Cantón R.

Emerg Infect Dis. 2001 Jan-Feb;7(1):113-22.


Evaluation of phenotypic and genotypic markers for characterisation of the emerging gastroenteritis pathogen Salmonella hadar.

Valdezate S, Echeita A, Díez R, Usera MA.

Eur J Clin Microbiol Infect Dis. 2000 Apr;19(4):275-81.


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