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The clinical profiles of female patients with Fabry disease in Latin America: A Fabry Registry analysis of natural history data from 169 patients based on enzyme replacement therapy status.

Martins AM, Cabrera G, Molt F, Suárez-Obando F, Valdés RA, Varas C, Yang M, Politei JM.

JIMD Rep. 2019 Aug 5;49(1):107-117. doi: 10.1002/jmd2.12071. eCollection 2019 Sep.


Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.

Ngoungoure VLN, Muñoz P, Tizabi Y, Valdes R, Moundipa PF, Segura-Aguilar J.

Clin Pharmacol Transl Med. 2019;3(1):125-133. Epub 2019 Apr 8.


Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets.

Cuyàs E, Castillo D, Llorach-Parés L, Lozano-Sánchez J, Verdura S, Nonell-Canals A, Brunet J, Bosch-Barrera J, Joven J, Valdés R, Sanchez-Martinez M, Segura-Carretero A, Menendez JA.

Food Chem Toxicol. 2019 Sep;131:110529. doi: 10.1016/j.fct.2019.05.037. Epub 2019 May 29.


End-stage renal disease-financial costs and years of life lost in Panama: a cost-analysis study.

Moreno Velásquez I, Tribaldos Causadias M, Valdés R, Gómez B, Motta J, Cuero C, Herrera-Ballesteros V.

BMJ Open. 2019 May 27;9(5):e027229. doi: 10.1136/bmjopen-2018-027229.


Cell-free DNA diagnostics: current and emerging applications in oncology.

Muluhngwi P, Valdes R Jr, Fernandez-Botran R, Burton E, Williams B, Linder MW.

Pharmacogenomics. 2019 Apr;20(5):357-380. doi: 10.2217/pgs-2018-0174. Epub 2019 Apr 15.


Patients with acute cervical insufficiency without intra-amniotic infection/inflammation treated with cerclage have a good prognosis.

Mönckeberg M, Valdés R, Kusanovic JP, Schepeler M, Nien JK, Pertossi E, Silva P, Silva K, Venegas P, Guajardo U, Romero R, Illanes SE.

J Perinat Med. 2019 Jul 26;47(5):500-509. doi: 10.1515/jpm-2018-0388.


Comparison of two identification and susceptibility test kits for Ureaplasma spp and Mycoplasma hominis in amniotic fluid of patients at high risk for intra-amniotic infection.

Kusanovic JP, Vargas P, Ferrer F, Díaz F, Córdova V, Martinovic C, Valdés R, Rosas A, Luna D, Silva P, Silva K, Nilo ME, Silva MJ, Espejo E, Zambrano MA, García J, Parra-Lara LG, Escobar MF.

J Matern Fetal Neonatal Med. 2019 Feb 20:1-9. doi: 10.1080/14767058.2019.1572742. [Epub ahead of print]


Coli Surface Antigen 26 Acts as an Adherence Determinant of Enterotoxigenic Escherichia coli and Is Cross-Recognized by Anti-CS20 Antibodies.

Cádiz L, Torres A, Valdés R, Vera G, Gutiérrez D, Levine MM, Montero DA, O'Ryan M, Rasko DA, Stine OC, Vidal R, Del Canto F.

Front Microbiol. 2018 Oct 16;9:2463. doi: 10.3389/fmicb.2018.02463. eCollection 2018.


Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 antigen.

Sordo Y, Suárez M, Caraballo R, Sardina T, Brown E, Duarte C, Lugo J, Gil L, Perez D, Oliva A, Vargas M, Santana E, Valdés R, Rodríguez MP.

Biologicals. 2018 Mar;52:67-71. doi: 10.1016/j.biologicals.2017.12.004. Epub 2018 Jan 5.


An ELISA for quantification of recombinant human EGF in production process samples, serum and urine.

Leyva A, Santana H, Font M, Pérez B, Valdés R.

Biologicals. 2018 Jan;51:12-17. doi: 10.1016/j.biologicals.2017.12.001. Epub 2017 Dec 12.


Model analysis of bidirectional interference in two-stage labeled-ligand immunoassays.

Lewin ER, Dasgupta A, Valdes R Jr, Stickle DF.

Clin Biochem. 2017 Dec;50(18):1188-1197. doi: 10.1016/j.clinbiochem.2017.08.005. Epub 2017 Aug 10.


Demonstration of the Maintaining of the Validated State of a System Used to Generate Water for Injection by Thermocompression Distillation.

Leyva A, Bisquet I, De La Cruz T, Del Arco L, Ríos J, Valdés R, Robles S, Ugarte F, Montané M.

PDA J Pharm Sci Technol. 2017 Nov-Dec;71(6):454-461. doi: 10.5731/pdajpst.2017.007773. Epub 2017 Jul 20.


Transabdominal collection of amniotic fluid "sludge" and identification of Candida albicans intra-amniotic infection.

Kusanovic JP, Romero R, Martinovic C, Silva K, Erez O, Maymon E, Díaz F, Ferrer F, Valdés R, Córdova V, Vargas P, Nilo ME, Le Cerf P.

J Matern Fetal Neonatal Med. 2018 May;31(10):1279-1284. doi: 10.1080/14767058.2017.1315095. Epub 2017 May 3.


Two-color pyrometry for low amplitude periodic heating.

Bennett TD, Silveira VB, Valdes R.

Rev Sci Instrum. 2017 Feb;88(2):024903. doi: 10.1063/1.4975927.


Arborizing vessels in a targetoid hemosiderotic hemangioma: mistaken dermoscopic diagnosis of basal cell carcinoma.

Enei ML, Paschoal FM, Valdes R.

Dermatol Pract Concept. 2017 Jan 31;7(1):43-47. doi: 10.5826/dpc.0701a08. eCollection 2017 Jan.


Chaperone-Usher Pili Loci of Colonization Factor-Negative Human Enterotoxigenic Escherichia coli.

Del Canto F, O'Ryan M, Pardo M, Torres A, Gutiérrez D, Cádiz L, Valdés R, Mansilla A, Martínez R, Hernández D, Caro B, Levine MM, Rasko DA, Hill CM, Pop M, Stine OC, Vidal R.

Front Cell Infect Microbiol. 2017 Jan 6;6:200. doi: 10.3389/fcimb.2016.00200. eCollection 2016.


Confirmed clinical case of chronic kidney disease of nontraditional causes in agricultural communities in Central America: a case definition for surveillance.

Ferreiro A, Álvarez-Estévez G, Cerdas-Calderón M, Cruz-Trujillo Z, Mena E, Reyes M, Sandoval-Diaz M, Sánchez-Polo V, Valdés R, Ordúnez P.

Rev Panam Salud Publica. 2016 Nov;40(5):301-308.



Reynolds KK, Valdes R Jr.

Clin Lab Med. 2016 Sep;36(3):xi-xiii. doi: 10.1016/j.cll.2016.06.001. No abstract available.


Fundamentals of Pharmacogenetics in Personalized, Precision Medicine.

Valdes R Jr, Yin DT.

Clin Lab Med. 2016 Sep;36(3):447-59. doi: 10.1016/j.cll.2016.05.006. Epub 2016 Jul 2. Review.


Liquid Biopsies in Oncology and the Current Regulatory Landscape.

Strotman LN, Millner LM, Valdes R Jr, Linder MW.

Mol Diagn Ther. 2016 Oct;20(5):429-36. doi: 10.1007/s40291-016-0220-5. Review.


Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responses.

Millar JA, Valdés R, Kacharia FR, Landfear SM, Cambronne ED, Raghavan R.

Front Microbiol. 2015 Aug 7;6:794. doi: 10.3389/fmicb.2015.00794. eCollection 2015.


Coating thermal diffusivity and effusivity measurement optimization using regression-based sensitivity.

Valdes R, Bennett TD.

Rev Sci Instrum. 2015 Jan;86(1):015108. doi: 10.1063/1.4905573.


Increased lung and bladder cancer incidence in adults after in utero and early-life arsenic exposure.

Steinmaus C, Ferreccio C, Acevedo J, Yuan Y, Liaw J, Durán V, Cuevas S, García J, Meza R, Valdés R, Valdés G, Benítez H, VanderLinde V, Villagra V, Cantor KP, Moore LE, Perez SG, Steinmaus S, Smith AH.

Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1529-38. doi: 10.1158/1055-9965.EPI-14-0059. Epub 2014 May 23.


Epigenetic primer for diagnostic applications: a window into personalized medicine.

McNally B, Linder M, Valdes R Jr.

Per Med. 2014 May;11(3):323-337. doi: 10.2217/pme.14.21.


[Acrodermatitis enteropathica: report of one case].

Valdés R, Mauret M, Castro Á.

Rev Med Chil. 2013 Nov;141(11):1480-3. doi: 10.4067/S0034-98872013001100017. Review. Spanish.


Identification of the intracellular gate for a member of the equilibrative nucleoside transporter (ENT) family.

Valdés R, Elferich J, Shinde U, Landfear SM.

J Biol Chem. 2014 Mar 28;289(13):8799-809. doi: 10.1074/jbc.M113.546960. Epub 2014 Feb 4.


Platelet serotonin concentration and clinical status in alcohol withdrawal syndrome, preliminary results.

Llinás SG, Caballero AJ, Peñalver JC, Valdés R.

MEDICC Rev. 2014 Jan;16(1):37-42.


Respiratory disease and particulate air pollution in Santiago Chile: contribution of erosion particles from fine sediments.

Garcia-Chevesich PA, Alvarado S, Neary DG, Valdes R, Valdes J, Aguirre JJ, Mena M, Pizarro R, Jofré P, Vera M, Olivares C.

Environ Pollut. 2014 Apr;187:202-5. doi: 10.1016/j.envpol.2013.12.028. Epub 2014 Jan 31.


Factors associated to depression in renal transplant recipients in Panama.

Vásquez V, Novarro N, Valdés RA, Britton GB.

Indian J Psychiatry. 2013 Jul;55(3):273-8. doi: 10.4103/0019-5545.117148.


Circulating tumor cells: a review of present methods and the need to identify heterogeneous phenotypes.

Millner LM, Linder MW, Valdes R Jr.

Ann Clin Lab Sci. 2013 Summer;43(3):295-304. Review.


[Bacteremia and pneumonia due to Alcaligenes xylosoxidans in a immunocompetent patient].

Villamil I, Valdés R, Villacán MJ, Masa L.

Rev Chilena Infectol. 2013 Jun;30(3):329. doi: 10.4067/S0716-10182013000300011. Spanish. No abstract available.


Argyria mimicking a blue nevis: dermoscopy features.

Enei ML, Paschoal FM, Valdés R.

An Bras Dermatol. 2013 May-Jun;88(3):452-5. doi: 10.1590/abd1806-4841.20132022.


Case-control study of arsenic in drinking water and kidney cancer in uniquely exposed Northern Chile.

Ferreccio C, Smith AH, Durán V, Barlaro T, Benítez H, Valdés R, Aguirre JJ, Moore LE, Acevedo J, Vásquez MI, Pérez L, Yuan Y, Liaw J, Cantor KP, Steinmaus C.

Am J Epidemiol. 2013 Sep 1;178(5):813-8. doi: 10.1093/aje/kwt059. Epub 2013 Jun 13.


Nosocomial ventilator-associated pneumonia in Cuban intensive care units: bacterial species and antibiotic resistance.

Medell M, Hart M, Duquesne A, Espinosa F, Valdés R.

MEDICC Rev. 2013 Apr;15(2):26-9.


Association between serum uric acid levels and cardiovascular risk among university workers from the State of Mexico: a nested case-control study.

Cerecero P, Hernández-Prado B, Denova E, Valdés R, Vázquez G, Camarillo E, Huitrón G.

BMC Public Health. 2013 May 1;13:415. doi: 10.1186/1471-2458-13-415.


Cysteine cross-linking defines the extracellular gate for the Leishmania donovani nucleoside transporter 1.1 (LdNT1.1).

Valdés R, Shinde U, Landfear SM.

J Biol Chem. 2012 Dec 28;287(53):44036-45. doi: 10.1074/jbc.M112.414433. Epub 2012 Nov 13.


[Sex-hormone binding globulin (SHBG) levels during pregnancy as predictors for pre-eclampsia and fetal growth restriction].

Valdés R E, Lattes A K, Muñoz S H, Cumsille MA.

Rev Med Chil. 2012 May;140(5):589-94. doi: 10.4067/S0034-98872012000500005. Spanish.


Improvements to surrogate data methods for nonstationary time series.

Lucio JH, Valdés R, Rodríguez LR.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 May;85(5 Pt 2):056202. Epub 2012 May 9.


Clinical and microbiological characterization of pneumonia in mechanically ventilated patients.

Medell M, Hart M, Marrero O, Espinosa F, Montes de Oca Z, Valdés R.

Braz J Infect Dis. 2012 Sep-Oct;16(5):442-7. doi: 10.1016/j.bjid.2012.08.005. Epub 2012 Sep 10.


Basal cell carcinoma appearing in a facial nevus sebaceous of Jadassohn: dermoscopic features.

Enei ML, Paschoal FM, Valdés G, Valdés R.

An Bras Dermatol. 2012 Jul-Aug;87(4):640-2.


Prospective pilot trial of PerMIT versus standard anticoagulation service management of patients initiating oral anticoagulation.

Borgman MP, Pendleton RC, McMillin GA, Reynolds KK, Vazquez S, Freeman A, Wilson A, Valdes R Jr, Linder MW.

Thromb Haemost. 2012 Sep;108(3):561-9. doi: 10.1160/TH12-03-0159. Epub 2012 Jul 26.


A diagnostic informatics approach for stratifying risk outcome based on combined genotype effects.

Yang L, Valdes R Jr, Taubert D, Linder MW.

Ther Drug Monit. 2012 Jun;34(3):283-8. doi: 10.1097/FTD.0b013e31824cf0ca.


Application of a risk analysis method to different technologies for producing a monoclonal antibody employed in hepatitis B vaccine manufacturing.

Milá L, Valdés R, Tamayo A, Padilla S, Ferro W.

Biologicals. 2012 Mar;40(2):118-28. doi: 10.1016/j.biologicals.2011.12.004. Epub 2012 Jan 28.


Validation of model virus removal and inactivation capacity of an erythropoietin purification process.

Pérez M, Rodríguez E, Rodríguez M, Paez R, Ruibal I, Noa E, García O, Moya G, Martínez M, Marcelo J, Martínez A, Dubal M, Navea L, Valdés R.

Biologicals. 2011 Nov;39(6):430-7. doi: 10.1016/j.biologicals.2011.09.006. Epub 2011 Oct 8.


Imbalanced low-grade inflammation and endothelial activation in patients with type 2 diabetes mellitus and erectile dysfunction.

Araña Rosaínz Mde J, Ojeda MO, Acosta JR, Elías-Calles LC, González NO, Herrera OT, García Álvarez CT, Rodríguez EM, Báez ME, Seijas EÁ, Valdés RF.

J Sex Med. 2011 Jul;8(7):2017-30. doi: 10.1111/j.1743-6109.2011.02277.x. Epub 2011 May 6.


Chronic toxicity, genotoxic assay, and phytochemical analysis of four traditional medicinal plants.

Castañeda Sortibrán A, Téllez MG, Ocotero VM, Carballo-Ontiveros MA, García AM, Valdés RJ, Gutiérrez ER, Rodríguez-Arnaiz R.

J Med Food. 2011 Sep;14(9):1018-22. doi: 10.1089/jmf.2010.0178. Epub 2011 May 9.


Novel and sensitive ELISA for the rapid quantification of recombinant p64K protein.

Leyva A, Sánchez JC, Alvarez D, Pérez B, López L, Paz S, Torres E, González T, Font M, Hernández N, Valdés R.

J Pharm Biomed Anal. 2011 Jun 1;55(3):403-8. doi: 10.1016/j.jpba.2011.01.041. Epub 2011 Mar 3.


[Acute viral hepatitis during pregnancy].

Valdés R E, Sepúlveda M A, Candia P P, Lattes A K.

Rev Chilena Infectol. 2010 Dec;27(6):505-12. doi: /S0716-10182010000700003. Epub 2011 Jan 7. Review. Spanish.


Effects of indole-3-acetic acid on Botrytis cinerea isolates obtained from potted plants.

Martínez JA, Valdés R, Gómez-Bellot MJ, Bañón S.

Commun Agric Appl Biol Sci. 2011;76(4):643-51.


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