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Items: 1 to 50 of 216

1.

Neuropathic-like knee pain and associated risk factors: a cross-sectional study in a UK community sample.

Fernandes GS, Valdes AM, Walsh DA, Zhang W, Doherty M.

Arthritis Res Ther. 2018 Sep 27;20(1):215. doi: 10.1186/s13075-018-1717-6.

2.

Contribution of central and peripheral risk factors to prevalence, incidence and progression of knee pain: a community-based cohort study.

Sarmanova A, Fernandes GS, Richardson H, Valdes AM, Walsh DA, Zhang W, Doherty M.

Osteoarthritis Cartilage. 2018 Aug 10. pii: S1063-4584(18)31388-8. doi: 10.1016/j.joca.2018.07.013. [Epub ahead of print]

3.

Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis.

Valdes AM, Ravipati S, Pousinis P, Menni C, Mangino M, Abhishek A, Chapman V, Barrett DA, Doherty M.

J Lipid Res. 2018 Sep;59(9):1763-1770. doi: 10.1194/jlr.P085118. Epub 2018 Jul 9.

4.

Bidirectional association between disturbed sleep and neuropathic pain symptoms: a prospective cohort study in post-total joint replacement participants.

Stocks J, Tang NK, Walsh DA, Warner SC, Harvey HL, Jenkins W, Abhishek A, Doherty M, Valdes AM.

J Pain Res. 2018 Jun 6;11:1087-1093. doi: 10.2147/JPR.S149830. eCollection 2018.

5.

Big data boost for osteoarthritis genetics.

Gonzalez A, Valdes AM.

Nat Rev Rheumatol. 2018 Jul;14(7):387-388. doi: 10.1038/s41584-018-0023-7. No abstract available.

PMID:
29899548
6.

Role of the gut microbiota in nutrition and health.

Valdes AM, Walter J, Segal E, Spector TD.

BMJ. 2018 Jun 13;361:k2179. doi: 10.1136/bmj.k2179. No abstract available.

7.

The fecal metabolome as a functional readout of the gut microbiome.

Zierer J, Jackson MA, Kastenmüller G, Mangino M, Long T, Telenti A, Mohney RP, Small KS, Bell JT, Steves CJ, Valdes AM, Spector TD, Menni C.

Nat Genet. 2018 Jun;50(6):790-795. doi: 10.1038/s41588-018-0135-7. Epub 2018 May 28.

PMID:
29808030
8.
9.

Gut microbial diversity is associated with lower arterial stiffness in women.

Menni C, Lin C, Cecelja M, Mangino M, Matey-Hernandez ML, Keehn L, Mohney RP, Steves CJ, Spector TD, Kuo CF, Chowienczyk P, Valdes AM.

Eur Heart J. 2018 Jul 1;39(25):2390-2397. doi: 10.1093/eurheartj/ehy226.

10.

Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes.

Blanco FJ, Valdes AM, Rego-Pérez I.

Nat Rev Rheumatol. 2018 Jun;14(6):327-340. doi: 10.1038/s41584-018-0001-0. Review.

PMID:
29670212
11.

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Jan Hottenga J, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG, Hinds DA, Kayser M, Spector TD; International Visible Trait Genetics Consortium; International Visible Trait Genetics Consortium.

Nat Genet. 2018 May;50(5):652-656. doi: 10.1038/s41588-018-0100-5. Epub 2018 Apr 16.

12.

Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress.

Metrustry SJ, Karhunen V, Edwards MH, Menni C, Geisendorfer T, Huber A, Reichel C, Dennison EM, Cooper C, Spector T, Jarvelin MR, Valdes AM.

PLoS One. 2018 Mar 22;13(3):e0194316. doi: 10.1371/journal.pone.0194316. eCollection 2018.

13.

Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts.

Menni C, Gudelj I, Macdonald-Dunlop E, Mangino M, Zierer J, Bešić E, Joshi PK, Trbojević-Akmačić I, Chowienczyk PJ, Spector TD, Wilson JF, Lauc G, Valdes AM.

Circ Res. 2018 May 25;122(11):1555-1564. doi: 10.1161/CIRCRESAHA.117.312174. Epub 2018 Mar 13.

14.

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Jiang X, O'Reilly PF, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Berry D, Kestenbaum B, Zheng J, Luan J, Sofianopoulou E, Streeten EA, Albanes D, Lutsey PL, Yao L, Tang W, Econs MJ, Wallaschofski H, Völzke H, Zhou A, Power C, McCarthy MI, Michos ED, Boerwinkle E, Weinstein SJ, Freedman ND, Huang WY, Van Schoor NM, van der Velde N, Groot LCPGM, Enneman A, Cupples LA, Booth SL, Vasan RS, Liu CT, Zhou Y, Ripatti S, Ohlsson C, Vandenput L, Lorentzon M, Eriksson JG, Shea MK, Houston DK, Kritchevsky SB, Liu Y, Lohman KK, Ferrucci L, Peacock M, Gieger C, Beekman M, Slagboom E, Deelen J, Heemst DV, Kleber ME, März W, de Boer IH, Wood AC, Rotter JI, Rich SS, Robinson-Cohen C, den Heijer M, Jarvelin MR, Cavadino A, Joshi PK, Wilson JF, Hayward C, Lind L, Michaëlsson K, Trompet S, Zillikens MC, Uitterlinden AG, Rivadeneira F, Broer L, Zgaga L, Campbell H, Theodoratou E, Farrington SM, Timofeeva M, Dunlop MG, Valdes AM, Tikkanen E, Lehtimäki T, Lyytikäinen LP, Kähönen M, Raitakari OT, Mikkilä V, Ikram MA, Sattar N, Jukema JW, Wareham NJ, Langenberg C, Forouhi NG, Gundersen TE, Khaw KT, Butterworth AS, Danesh J, Spector T, Wang TJ, Hyppönen E, Kraft P, Kiel DP.

Nat Commun. 2018 Jan 17;9(1):260. doi: 10.1038/s41467-017-02662-2.

15.

Genetic and microbiome influence on lipid metabolism and dyslipidemia.

Matey-Hernandez ML, Williams FMK, Potter T, Valdes AM, Spector TD, Menni C.

Physiol Genomics. 2018 Feb 1;50(2):117-126. doi: 10.1152/physiolgenomics.00053.2017. Epub 2017 Dec 20.

PMID:
29341867
16.

Association between ultrasound-detected synovitis and knee pain: a population-based case-control study with both cross-sectional and follow-up data.

Sarmanova A, Hall M, Fernandes GS, Bhattacharya A, Valdes AM, Walsh DA, Doherty M, Zhang W.

Arthritis Res Ther. 2017 Dec 19;19(1):281. doi: 10.1186/s13075-017-1486-7.

17.

Neuropathic pain-like symptoms and pre-surgery radiographic severity contribute to patient satisfaction 4.8 years post-total joint replacement.

Warner SC, Richardson H, Jenkins W, Kurien T, Doherty M, Valdes AM.

World J Orthop. 2017 Oct 18;8(10):761-769. doi: 10.5312/wjo.v8.i10.761. eCollection 2017 Oct 18.

18.

Triggers of acute attacks of gout, does age of gout onset matter? A primary care based cross-sectional study.

Abhishek A, Valdes AM, Jenkins W, Zhang W, Doherty M.

PLoS One. 2017 Oct 12;12(10):e0186096. doi: 10.1371/journal.pone.0186096. eCollection 2017.

19.

Prevalence of tooth forms and their gender correlation.

Mahn E, Walls S, Jorquera G, Valdés AM, Val A, Sampaio CS.

J Esthet Restor Dent. 2018 Jan;30(1):45-50. doi: 10.1111/jerd.12341. Epub 2017 Sep 29.

PMID:
28960683
20.

Knee pain and related health in the community study (KPIC): a cohort study protocol.

Fernandes GS, Sarmanova A, Warner S, Harvey H, Akin-Akinyosoye K, Richardson H, Frowd N, Marshall L, Stocks J, Hall M, Valdes AM, Walsh D, Zhang W, Doherty M.

BMC Musculoskelet Disord. 2017 Sep 21;18(1):404. doi: 10.1186/s12891-017-1761-4.

21.

Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women.

Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM.

Sci Rep. 2017 Sep 11;7(1):11079. doi: 10.1038/s41598-017-10382-2.

22.

Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans.

Valdes AM, Ravipati S, Menni C, Abhishek A, Metrustry S, Harris J, Nessa A, Williams FMK, Spector TD, Doherty M, Chapman V, Barrett DA.

Sci Rep. 2017 Sep 7;7(1):10748. doi: 10.1038/s41598-017-09516-3.

23.

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.

den Hollander W, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB.

Ann Rheum Dis. 2017 Dec;76(12):2046-2053. doi: 10.1136/annrheumdis-2017-211214. Epub 2017 Aug 30.

24.

Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain.

Menni C, Migaud M, Kastenmüller G, Pallister T, Zierer J, Peters A, Mohney RP, Spector TD, Bagnardi V, Gieger C, Moore SC, Valdes AM.

Obesity (Silver Spring). 2017 Sep;25(9):1618-1624. doi: 10.1002/oby.21922. Epub 2017 Jul 31.

25.

First validation of the gout activity score against gout impact scale in a primary care based gout cohort.

La-Crette J, Jenkins W, Fernandes G, Valdes AM, Doherty M, Abhishek A.

Joint Bone Spine. 2018 May;85(3):323-325. doi: 10.1016/j.jbspin.2017.05.010. Epub 2017 May 17.

PMID:
28528279
26.

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.

Warner SC, Walsh DA, Laslett LL, Maciewicz RA, Soni A, Hart DJ, Zhang W, Muir KR, Dennison EM, Leaverton P, Rampersaud E, Cooper C, Spector TD, Cicuttini FM, Arden NK, Jones G, Doherty M, Valdes AM.

Eur J Pain. 2017 Aug;21(7):1277-1284. doi: 10.1002/ejp.1027. Epub 2017 May 11.

27.

Molecular pathways associated with blood pressure and hexadecanedioate levels.

Menni C, Metrustry SJ, Ehret G, Dominiczak AF, Chowienczyk P, Spector TD, Padmanabhan S, Valdes AM.

PLoS One. 2017 Apr 12;12(4):e0175479. doi: 10.1371/journal.pone.0175479. eCollection 2017.

28.

Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling.

Pallister T, Jackson MA, Martin TC, Glastonbury CA, Jennings A, Beaumont M, Mohney RP, Small KS, MacGregor A, Steves CJ, Cassidy A, Spector TD, Menni C, Valdes AM.

Int J Obes (Lond). 2017 Jul;41(7):1106-1113. doi: 10.1038/ijo.2017.70. Epub 2017 Mar 15.

29.

Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain.

Menni C, Jackson MA, Pallister T, Steves CJ, Spector TD, Valdes AM.

Int J Obes (Lond). 2017 Jul;41(7):1099-1105. doi: 10.1038/ijo.2017.66. Epub 2017 Mar 13.

30.

Familial aggregation of rheumatoid arthritis and co-aggregation of autoimmune diseases in affected families: a nationwide population-based study.

Kuo CF, Grainge MJ, Valdes AM, See LC, Yu KH, Shaw SWS, Luo SF, Zhang W, Doherty M.

Rheumatology (Oxford). 2017 Jun 1;56(6):928-933. doi: 10.1093/rheumatology/kew500.

31.

Mixing omics: combining genetics and metabolomics to study rheumatic diseases.

Menni C, Zierer J, Valdes AM, Spector TD.

Nat Rev Rheumatol. 2017 Mar;13(3):174-181. doi: 10.1038/nrrheum.2017.5. Epub 2017 Feb 2. Review.

PMID:
28148918
32.

Mitochondrial DNA haplogroups and ageing mechanisms in osteoarthritis.

Valdes AM, Goldring MB.

Ann Rheum Dis. 2017 Jun;76(6):939-941. doi: 10.1136/annrheumdis-2016-210783. Epub 2017 Jan 9. No abstract available.

PMID:
28069577
33.

Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene.

Warner SC, van Meurs JB, Schiphof D, Bierma-Zeinstra SM, Hofman A, Uitterlinden AG, Richardson H, Jenkins W, Doherty M, Valdes AM.

Eur J Hum Genet. 2017 Apr;25(4):446-451. doi: 10.1038/ejhg.2016.196. Epub 2017 Jan 4.

34.

Familial Aggregation and Heritability of Schizophrenia and Co-aggregation of Psychiatric Illnesses in Affected Families.

Chou IJ, Kuo CF, Huang YS, Grainge MJ, Valdes AM, See LC, Yu KH, Luo SF, Huang LS, Tseng WY, Zhang W, Doherty M.

Schizophr Bull. 2017 Sep 1;43(5):1070-1078. doi: 10.1093/schbul/sbw159.

35.

Genetic association studies in osteoarthritis: is it fairytale?

Warner SC, Valdes AM.

Curr Opin Rheumatol. 2017 Jan;29(1):103-109. Review.

PMID:
27755178
36.

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, Zhang W, Kraaij R, Rivadeneira F, Barrett-Connor E, Maciewicz RA, Arden N, Nelissen RG, Kloppenburg M, Jordan JM, Nevitt MC, Slagboom EP, Hart DJ, Lafeber F, Styrkarsdottir U, Zeggini E, Evangelou E, Spector TD, Uitterlinden AG, Lane NE, Meulenbelt I, Valdes AM, van Meurs JB.

PLoS Genet. 2016 Oct 4;12(10):e1006260. doi: 10.1371/journal.pgen.1006260. eCollection 2016 Oct.

37.

Association of Beta-Blocker Use With Less Prevalent Joint Pain and Lower Opioid Requirement in People With Osteoarthritis.

Valdes AM, Abhishek A, Muir K, Zhang W, Maciewicz RA, Doherty M.

Arthritis Care Res (Hoboken). 2017 Jul;69(7):1076-1081. doi: 10.1002/acr.23091. Epub 2017 Jun 7.

38.

Analysis and Visualization Tool for Targeted Amplicon Bisulfite Sequencing on Ion Torrent Sequencers.

Pabinger S, Ernst K, Pulverer W, Kallmeyer R, Valdes AM, Metrustry S, Katic D, Nuzzo A, Kriegner A, Vierlinger K, Weinhaeusel A.

PLoS One. 2016 Jul 28;11(7):e0160227. doi: 10.1371/journal.pone.0160227. eCollection 2016.

39.

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Prins BP, Abbasi A, Wong A, Vaez A, Nolte I, Franceschini N, Stuart PE, Guterriez Achury J, Mistry V, Bradfield JP, Valdes AM, Bras J, Shatunov A; PAGE Consortium; International Stroke Genetics Consortium; Systemic Sclerosis consortium; Treat OA consortium; DIAGRAM Consortium; CARDIoGRAMplusC4D Consortium; ALS consortium; International Parkinson’s Disease Genomics Consortium; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; CKDGen consortium; GERAD1 Consortium; International Consortium for Blood Pressure; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Inflammation Working Group of the CHARGE Consortium, Lu C, Han B, Raychaudhuri S, Bevan S, Mayes MD, Tsoi LC, Evangelou E, Nair RP, Grant SF, Polychronakos C, Radstake TR, van Heel DA, Dunstan ML, Wood NW, Al-Chalabi A, Dehghan A, Hakonarson H, Markus HS, Elder JT, Knight J, Arking DE, Spector TD, Koeleman BP, van Duijn CM, Martin J, Morris AP, Weersma RK, Wijmenga C, Munroe PB, Perry JR, Pouget JG, Jamshidi Y, Snieder H, Alizadeh BZ.

PLoS Med. 2016 Jun 21;13(6):e1001976. doi: 10.1371/journal.pmed.1001976. eCollection 2016 Jun.

40.

Intercritical circulating levels of neo-epitopes reflecting matrixmetalloprotease-driven degradation as markers of gout and frequent gout attacks.

Valdes AM, Manon-Jensen T, Abhishek A, Jenkins W, Siebuhr AS, Karsdal MA, Doherty S, Zhang W, Richardson H, Doherty M, Bay-Jensen AC.

Rheumatology (Oxford). 2016 Sep;55(9):1642-6. doi: 10.1093/rheumatology/kew235. Epub 2016 Jun 2.

PMID:
27256715
41.

Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health.

Menni C, Migaud M, Glastonbury CA, Beaumont M, Nikolaou A, Small KS, Brosnan MJ, Mohney RP, Spector TD, Valdes AM.

Obesity (Silver Spring). 2016 Jun;24(6):1380-8. doi: 10.1002/oby.21488. Epub 2016 Apr 30.

42.

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study.

Altmaier E, Menni C, Heier M, Meisinger C, Thorand B, Quell J, Kobl M, Römisch-Margl W, Valdes AM, Mangino M, Waldenberger M, Strauch K, Illig T, Adamski J, Spector T, Gieger C, Suhre K, Kastenmüller G.

PLoS One. 2016 Apr 27;11(4):e0153163. doi: 10.1371/journal.pone.0153163. eCollection 2016.

43.

Association of Serum Uric Acid and Disease Duration With Frequent Gout Attacks: A Case-Control Study.

Abhishek A, Valdes AM, Zhang W, Doherty M.

Arthritis Care Res (Hoboken). 2016 Oct;68(10):1573-7. doi: 10.1002/acr.22855. Epub 2016 Sep 2.

44.

Low omega-3 fatty acid levels associate with frequent gout attacks: a case control study.

Abhishek A, Valdes AM, Doherty M.

Ann Rheum Dis. 2016 Apr;75(4):784-5. doi: 10.1136/annrheumdis-2015-208767. Epub 2015 Dec 29. No abstract available.

PMID:
26715654
45.

DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins.

Tsai PC, Van Dongen J, Tan Q, Willemsen G, Christiansen L, Boomsma DI, Spector TD, Valdes AM, Bell JT.

Twin Res Hum Genet. 2015 Dec;18(6):635-46. doi: 10.1017/thg.2015.76. Epub 2015 Nov 13.

PMID:
26563994
46.

KIR haplotypes are associated with late-onset type 1 diabetes in European-American families.

Traherne JA, Jiang W, Valdes AM, Hollenbach JA, Jayaraman J, Lane JA, Johnson C, Trowsdale J, Noble JA.

Genes Immun. 2016 Jan-Feb;17(1):8-12. doi: 10.1038/gene.2015.44. Epub 2015 Oct 22.

47.

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population.

Sekula P, Goek ON, Quaye L, Barrios C, Levey AS, Römisch-Margl W, Menni C, Yet I, Gieger C, Inker LA, Adamski J, Gronwald W, Illig T, Dettmer K, Krumsiek J, Oefner PJ, Valdes AM, Meisinger C, Coresh J, Spector TD, Mohney RP, Suhre K, Kastenmüller G, Köttgen A.

J Am Soc Nephrol. 2016 Apr;27(4):1175-88. doi: 10.1681/ASN.2014111099. Epub 2015 Oct 8.

48.

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families.

Kuo CF, Grainge MJ, Valdes AM, See LC, Luo SF, Yu KH, Zhang W, Doherty M.

JAMA Intern Med. 2015 Sep;175(9):1518-26. doi: 10.1001/jamainternmed.2015.3528.

PMID:
26193127
49.

Use of prescription analgesic medication and pain catastrophizing after total joint replacement surgery.

Valdes AM, Warner SC, Harvey HL, Fernandes GS, Doherty S, Jenkins W, Wheeler M, Doherty M.

Semin Arthritis Rheum. 2015 Oct;45(2):150-5. doi: 10.1016/j.semarthrit.2015.05.004. Epub 2015 May 20.

PMID:
26092331
50.

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate.

Menni C, Graham D, Kastenmüller G, Alharbi NH, Alsanosi SM, McBride M, Mangino M, Titcombe P, Shin SY, Psatha M, Geisendorfer T, Huber A, Peters A, Wang-Sattler R, Xu T, Brosnan MJ, Trimmer J, Reichel C, Mohney RP, Soranzo N, Edwards MH, Cooper C, Church AC, Suhre K, Gieger C, Dominiczak AF, Spector TD, Padmanabhan S, Valdes AM.

Hypertension. 2015 Aug;66(2):422-9. doi: 10.1161/HYPERTENSIONAHA.115.05544. Epub 2015 Jun 1.

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